Search clinical trials for: Single-ascending dose

Total 20922 results

Melanoma Institute Australia
Bristol-Myers Squibb

Not yet recruiting

Neoadjuvant Nivolumab and Relatlimab in Cutaneous Squamous Cell Carcinoma

Cutaneous Squamous Cell Carcinoma
Gerbera Therapeutics, Inc.

Not yet recruiting

A Study to Assess the Efficacy, Safety, and Tolerability of Oral NORA520 in Adults With Severe Postpartum Depression (NuMom)

Postpartum Depression | Depression, Postpartum | Postnatal Depression | Post-partum Depression | Post-Natal Depression

United States
Loyola University

Recruiting

Ketamine as a Supplement to Local Anesthesia for Minor Procedures (INK-MP)

Abscess | Pain, Procedural | Minor Laceration

United States
Samuel Lunenfeld Research Institute, Mount Sinai...

Recruiting

Comparing the Dose-response Profiles of Uterotonics After Initial Carbetocin Administration - an Ex-vivo Study in Desensitized Human Myometrium

Postpartum Hemorrhage

Canada
Nemysis Ltd
RDC Clinical Pty Ltd

Recruiting

Safety and Effectiveness of Iron Hydroxide Adipate Tartrate (IHAT) in Iron Deficient Premenopausal Women

Iron-deficiency

Australia
Albert Einstein College of Medicine
American Cancer Society, Inc.

Not yet recruiting

Centralized Screening Unit (CSU) at Montefiore-Einstein

Lung Cancer

United States
Agios Pharmaceuticals, Inc.

Recruiting

A Safety Study of Single and Multiple Doses of AG-181 in Healthy Participants

Healthy Volunteers

United States
Serum Institute of India Pvt. Ltd.
Bill and Melinda Gates Foundation

Not yet recruiting

Clinical Study to Evaluate SIIPL qHPV Vaccine (CERVAVAC®) in Women Living With HIV Aged 15-25 Years

Human Papillomavirus Infection

Kenya, Mozambique, South Africa
Advesya SAS

Not yet recruiting

An Adaptive Open-label Multicentre Phase 1/2 Trial, to Determine the Recommended Phase 2 Dose of CCTx-001, and to Assess Safety, Tolerability, and Clinical Activity in Patients With Relapsed/Refractory Acute Myeloid Leukaemia (RESOLVE AML001)

Acute Myeloid Leukemia, in Relapse | Acute Myeloid Leukemia Refractory

France, Sweden, Spain, Germany
The Netherlands Cancer Institute

Recruiting

A Pilot Study of Dose dE-eScalaTion IN prostATe radIOtherapy usiNg the MRL (DESTINATION)

Prostate Cancer

Netherlands
Vigonvita Life Sciences

Recruiting

Safety and Pharmacokinetics Study of Multiple Ascending Doses and Food Effect of LV232 Capsules

Healthy Subjects

China
Xi'an Xintong Pharmaceutical Research Co.,Ltd.

Recruiting

Safety, Tolerability Phase Ia Study of XT1061 in Single and Multiple Doses in Healthy Subjects (XT1061)

Chronic Hepatitis b

China
AstraZeneca

Recruiting

A Study Evaluating the Efficacy of Budesonide, Glycopyrronium and Formoterol Fumarate Metered Dosed Inhaler on Cardiopulmonary Outcomes in Chronic Obstructive Pulmonary Disease (THARROS)

COPD (Chronic Obstructive Pulmonary Disease)

France, Denmark, Italy, Spain, United States, Canada, Argentina, Japan, Colombia, Germany, Peru, Brazil, China, India, Thailand, Austria, Serbia, Malaysia, Philippines, Poland, Taiwan, Greece, Norway, Sweden, Mexico, Romania, Korea, Republic... and more
Alisse Hauspurg
National Heart, Lung, and Blood Institute (NHLBI)

Recruiting

Treatment With Aspirin After Preeclampsia: TAP Trial (TAP)

Cardiovascular Diseases | Vascular Diseases | Toxemia | Hypertension | Pregnancy Complications | Eclampsia | Pre-Eclampsia | Hypertensive Disorder of Pregnancy | Gestational Hypertension | Hypertension, Pregnancy Induced | Hypertension;Pre-Eclamptic

United States
Veru Inc.

Recruiting

Dose-Finding Study Evaluating Effect on Body Composition of Enobosarm in Patients Taking a GLP-1 for Chronic Weight Mgmt

Obesity | Muscle Loss

United States
Yuhan Corporation

Recruiting

Study to Evaluate the Efficacy and Safety of TEL/AML/CTD in Elderly Patients With Essential Hypertension

Essential Hypertension

Korea, Republic of
Denali Therapeutics Inc.

Recruiting

A Phase 1, Open-label Study of the Absorption, Metabolism, and Excretion of [14C]-DNL343 Following a Single Oral Dose in Healthy Male Participants

Healthy Volunteers

United States
Florida Atlantic University

Not yet recruiting

Machine Learning and 3D Image-based Modeling for Body Weight Estimation.

Weight, Body | Drug Dose | No Specific Conditions | Weight-Estimation
Suzhou Zelgen Biopharmaceuticals Co.,Ltd

Not yet recruiting

Dose Escalation Study of ZG006 in Participants With Advanced Small Cell Lung Cancer or Neuroendocrine Carcinoma, Followed by Dose Expansion Study in Participants With Advanced Small Cell Lung Cancer

Small Cell Lung Cancer | Neuroendocrine Cancer

China
Boehringer Ingelheim

Recruiting

A Study to Test Different Doses of BI 1569912 in People With Depression Who Take Anti-depressive Medicine

Depressive Disorder, Major

United States
University Hospital, Basel, Switzerland

Recruiting

Effects of Intravenous [Pyr1]Apelin-13 on Healthy Volunteers With Artificially Induced SIAD (ESCAPE)

Hyponatremia | SIAD - Syndrome of Inappropriate Antidiuresis

Switzerland
GEN İlaç ve Sağlık Ürünleri A.Ş.
Sulfateq B.V.

Recruiting

A First-In-Human Study of Single and Multiple Ascending Doses of Oral SUL-238 in Healthy Subjects

Healthy Subjects

Turkey
Jiangsu Aidea Pharmaceutical Co., Ltd
Chengdu Aidea Pharmaceutical Technology Co., Ltd

Recruiting

Single Ascending Dose, Food Effects and Drug-Drug Interactions of ACC017 Tablets in Healthy Adult Participants

Healthy Adult Participants

China
Rovi Pharmaceuticals Laboratories

Recruiting

Pharmacokinetics, Safety and Tolerability of Different Formulations and Dose Strengths of Quarterly Risperidone (QUAR) in Patients With Schizophrenia (QUARTZ)

Schizophrenia

Jordan
Drexel University

Recruiting

The Effects of an Acute Dose of a Betalain-rich Concentrate on Repeated-sprint Cycling Performance and Recovery. (BET_RSE)

Nutraceuticals

United States
ANRS, Emerging Infectious Diseases

Not yet recruiting

Impact of Long-acting Injectable Cabotegravir for HIV PrEP in MSM in France. (CABOPrEP)

Prevention

France
University of Mississippi Medical Center
The Craig H. Neilsen Foundation; Methodist Rehabilitation Center

Not yet recruiting

Neuromodulation to Reduce Muscle Stiffness Following Spinal Cord Injury

Spinal Cord Injuries | Spinal Cord Injury | Spinal Cord Injury Cervical | Spinal Cord Injury Thoracic

United States
Leiden University Medical Center
Dutch Colorectal Cancer Group; Stichting Darmkanker

Not yet recruiting

DOSAGE Study: Upfront Dose-Reduced Chemotherapy in Older Patients With Metastatic Colorectal Cancer (DOSAGE)

Colorectal Cancer | Metastatic Cancer | Older Patients | Candidates for Palliative Chemotherapy

Netherlands
Biora Therapeutics, Inc.

Recruiting

BT-600 Single and Multiple Ascending Oral Doses in Healthy Adult Subjects

Healthy

United States
University of Manitoba

Not yet recruiting

Croup Dosing Study

Croup
Polarean, Inc.
Aerogen

Recruiting

Comparison of Bronchodilator Response From Three Different Aerosol Delivery Methods in Patients With COPD Using Hyperpolarized Xe 129 MRI Ventilation Imaging

Chronic Obstructive Pulmonary Disease

United States
Ain Shams University

Not yet recruiting

Low Dose Atropine Eye Drops in Myopic Egyptian Children (LAMP)

Myopia Progression | Axial Length, Eye | Sclera Thickness

Egypt
Cairo University

Not yet recruiting

Fractional Carbon Dioxide Laser: A Novel Therapeutic Option for Lichen Simplex Chronicus

Lichen Simplex Chronicus

Egypt
Edward Geissler
Chiesi Pharmaceuticals GmbH

Recruiting

Tacrolimus C:D Ratio Measured in Renal Transplant Recipients Treated With Once-daily Prolonged-release Drugs (TaC:Drop)

Immunosuppression

Germany
Central Hospital, Nancy, France

Not yet recruiting

Pre-therapeutic 68Ga-PSMA PET AI Based Dose Prediction for 177Lu-PSMA Targeted Radionuclide Therapy (PADL)

Radionucleide Therapy
Universitat de Lleida
Pharmactive Biotech Products S.L.U

Recruiting

ABG+/GarlACE Effects on Cardiovascular Risk Factors in Subjects With Grade I Hypertension (GARDOSE)

Hypertension

Spain
Amneal Pharmaceuticals, LLC
CBCC Global Inc.; Amneal EU, Limited

Not yet recruiting

A Randomized, Double-blind, Parallel-group, Two-arm, Multiple Dose, Multicenter, Bioequivalence Study With Clinical Endpoint in the Treatment of Subjects With Chronic Open-angle Glaucoma or Ocular Hypertension in Both Eyes

Ocular Hypertension | Open-angle Glaucoma

United States
University of Alabama at Birmingham

Not yet recruiting

Trial of 2 Step ATG for Prevention of Acute GVHD Post Allogeneic Stem Cell Transplant

Myeloproliferative Disorders | Acute Leukemia | Myelodysplastic Syndrome

United States
Instituto de Investigación Hospital Universitario...
Instituto de Salud Carlos III

Not yet recruiting

Efficacy, Safety and Cost-efficacy of a Pre-emptive Genotyping Strategy in Patients Receiving Statins (PREVESTATGx)

Cardiovascular Diseases | Dyslipidemias | Statin Adverse Reaction | Pharmacogenic Myopathy

Spain
SPA Società Prodotti Antibiotici S.p.A.
Pharmaceutical Development and Services

Recruiting

Clinical Trial to Assess Efficacy, Tolerability of Rising Doses of Clodronate in Painful Knee Osteoarthritis Patients

Osteoarthritis of Knee

Italy
Medical University of Warsaw

Recruiting

Efficacy and Safety of Low-dose Sesame Oral Immunotherapy in Pediatric Patients

Food Allergy

Poland
M.D. Anderson Cancer Center

Not yet recruiting

Low-Dose Sirolimus to Increase Hematopoietic Function in Patients With RUNX1 Familial Platelet Disorder

Familial Platelet Disorder | Hematopoietic

United States
Egymedicalpedia

Recruiting

Low Dose Aspirin for Prevention of Early Pregnancy Loss

Pre-Eclampsia

Egypt
Tomsk National Research Medical Center of the Russian...

Recruiting

High-dose Inhaled NO Therapy for the pREvenvention of NP After Cardiac Surgery Under CPB

Nosocomial Pneumonia

Russian Federation
Tasly Pharmaceutical Group Co., Ltd

Recruiting

A Study of the Effectiveness and Safety of JS1-1-01 in Patients With Moderate to Severe Depression

Depression

China
Universidade Federal de Sao Carlos

Not yet recruiting

Pain Science Education Administered in Full or Fractioned Dosage Modes for Temporomandibular Disorders

Temporomandibular Joint Disorders

Brazil
GigaGen, Inc.
National Cancer Institute (NCI)

Recruiting

A Dose Escalation and Expansion Study of GIGA-564 in Participants With Locally Advanced or Metastatic Solid Tumor Malignancies

Advanced or Metastatic Solid Tumor Malignancies

United States
Wenzhou Central Hospital

Not yet recruiting

A Randomized Controlled Trial of Auricular Acupressure in Treating Estazolam-dependent Insomnia (ESAAEDI)

Estazolam-dependent Insomnia
Aummune Ltd.

Recruiting

Study of AM003 in Patients With Locally Advanced and Metastatic Solid Tumors

Solid Tumor

Israel
BrodenBio Co., Ltd.

Recruiting

A Phase 1 Study of BB102 in Participants With Advanced Solid Tumors

Advanced Solid Tumor

China

Search clinical trials for: Single-ascending dose

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