Search clinical trials for: Vascular endothelial growth factor (VEGF)

Total 83504 results

Jonsson Comprehensive Cancer Center
Genentech, Inc.

Completed

Bevacizumab and Temozolomide in Treating Older Patients With Newly-Diagnosed Glioblastoma Multiforme or Gliosarcoma

Glioblastoma | Gliosarcoma | Giant Cell Glioblastoma

United States
University Medical Center Groningen
UMC Utrecht

Completed

VEGF-targeted Fluorescent Tracer Imaging in Breast Cancer

Breast Cancer

Netherlands
National Cancer Institute (NCI)

Terminated

Aflibercept for Relapsed Multiple Myeloma

Stage II Multiple Myeloma | Stage III Multiple Myeloma

United States
The First Affiliated Hospital with Nanjing Medical...

Unknown

Day Regimes of CONbercept on CytokinEs of PDR Patients Undergoing Vitrectomy - Trial (CONCEPT) (CONCEPT)

Proliferative Diabetic Retinopathy | VEGF Overexpression

China
National Cancer Institute (NCI)
Eastern Cooperative Oncology Group; Cancer and Leukemia Group B; North Central...

Active, not recruiting

Doxorubicin Hydrochloride, Cyclophosphamide, and Paclitaxel With or Without Bevacizumab in Treating Patients With Lymph Node-Positive or High-Risk, Lymph Node-Negative Breast Cancer

Breast Adenocarcinoma

United States, Peru, South Africa
National Cancer Institute (NCI)

Active, not recruiting

A Study to Determine Whether Chemotherapy and Atezolizumab is Better Than Chemotherapy, Bevacizumab and Atezolizumab in Patients With Advanced Liver Cancer

Combined Hepatocellular Carcinoma and Cholangiocarcinoma | Stage III Liver Cancer | Stage IV Liver Cancer

United States
University of Sao Paulo

Completed

Prospective, Randomized Clinical Trial Comparing Macular Photocoagulation With or Without Intravitreal Bevacizumab or Triamcinolone for the Treatment of Diabetic Macular Edema (IBeTA)

Diabetic Macular Edema
University of Sao Paulo

Unknown

Intravitreal Triamcinolone Acetonide Versus Intravitreal Bevacizumab for Refractory Diabetic Macular Edema (IBEME Study) (IBEME)

Diabetic Macular Edema

Brazil
Wuhan Union Hospital, China

Completed

The Effects of VEGF-B Signaling Pathway in Obesity and Metabolic Disease (Obesity)

Obesity | Metabolic Disease

China
M.D. Anderson Cancer Center

Completed

Hepatic Arterial Infusion Oxaliplatin, Capecitabine With or Without Bevacizumab

Advanced Cancers

United States
Pusan National University Hospital
Bayer

Completed

Effect of Intravitreal VEGF-Trap Eye on Polypoidal Choroidal Vasculopathy (VAULT)

Polypoidal Choroidal Vasculopathy | Exudative Age-related Macular Degeneration

Korea, Republic of
Hellenic Oncology Research Group
University Hospital of Crete

Terminated

Combination of Erlotinib and Bevacizumab as Second-line Treatment in Patients With Non-small Cell Lung Cancer

Non-small-cell Lung Cancer

Greece
Keyvan Koushan

Completed

Treatment of Diabetic Macular Edema With Aflibercept and Micropulse Laser (DAM)

Diabetic Macular Edema

Canada
Taipei Medical University WanFang Hospital

Unknown

Study the Novel Functions and Molecular Mechanisms of Vascular Endothelial Growth Factor-C (VEGF-C) in Acute Myeloid Leukemia (AML)

Acute Myeloid Leukemia

Taiwan
Chang Gung Memorial Hospital

Unknown

The Role of Angiopoietin, Tie-2, and Vascular Endothelial Growth Factor (VEGF) in Sepsis-Induced Multiple Organ Dysfunction Syndrome (MODS)

Sepsis | Multiple Organ Dysfunction Syndrome

Taiwan
National Cancer Institute (NCI)

Completed

Aflibercept in Treating Patients With Recurrent and/or Metastatic Thyroid Cancer That Did Not Respond to Radioactive Iodine Therapy

Recurrent Thyroid Gland Carcinoma | Stage III Thyroid Gland Papillary Carcinoma | Stage IV Thyroid Gland Papillary Carcinoma | Stage III Thyroid Gland Follicular Carcinoma | Stage IV Thyroid Gland Follicular Carcinoma

United States
Raj K. Maturi, MD
Allergan

Completed

Anti-Vascular Endothelial Growth Factor (Anti-VEGF) Alone Versus Ozurdex Given Every 3 Months for Treatment of Persistent Diabetic Macular Edema

Diabetic Macular Edema

United States
Hospices Civils de Lyon

Completed

BABH Study: Efficacy and Safety of Bevacizumab on Severe Bleedings Associated With Hemorrhagic Hereditary Telangiectasia (HHT). (BABH)

Telangiectasia, Hereditary Hemorrhagic | Rendu Osler Disease

France
Universiti Sains Malaysia

Completed

Intralesional Ranibizumab on Pterygium Vascularity, Size and Recurrence Rate: a Pilot Study

Pterygium
GlaxoSmithKline

Completed

A Study To Evaluate The Safety, Tolerability And Pk Of Pazopanib Eye Drops In Healthy Adult And Elderly Subjects.

Macular Degeneration | Age-related Macular Degeneration

United States
Alcon Research

Completed

ESBA1008 Microvolume Study

Exudative Age-Related Macular Degeneration
Icahn School of Medicine at Mount Sinai
Centers for Disease Control and Prevention; U.S. Department of Education

Completed

Effects of Aerobic Exercise on Cognition, Mood and Fatigue Following TBI

Traumatic Brain Injury

United States
National Cancer Institute (NCI)

Recruiting

Testing of Bevacizumab, Erlotinib, and Atezolizumab in Combination for Advanced-Stage Kidney Cancer

Renal Cell Carcinoma | Stage III Renal Cell Cancer AJCC v8 | Stage IV Renal Cell Cancer AJCC v8 | Papillary Renal Cell Carcinoma | Hereditary Leiomyomatosis and Renal Cell Carcinoma | Sporadic Papillary Renal Cell Carcinoma

United States
Ning Jin

Active, not recruiting

Riluzole in Combination With mFOLFOX6 and Bevacizumab in Treating Patients With Metastatic Colorectal Cancer

Metastatic Colorectal Carcinoma | Stage IV Colorectal Cancer AJCC v8 | Stage IVA Colorectal Cancer AJCC v8 | Stage IVB Colorectal Cancer AJCC v8 | Stage IVC Colorectal Cancer AJCC v8

United States
Regeneron Pharmaceuticals

Not yet recruiting

An Observational Study to Investigate the Use of Aflibercept 8 mg to Treat Adult Patients With Neovascular Age-Related Macular Degeneration (nAMD) and Diabetic Macular Edema (DME) in a Real-World Setting (SPECTRUM-US)

Visual Impairment | Diabetic Macular Edema (DME) | Neovascular Age-related Macular Degeneration (nAMD) | Wet Age-related Macular Degeneration (AMD)
GlaxoSmithKline

Completed

An Extension to Study MD7108240

Macular Degeneration

Italy, United States, Australia
Bayer
Regeneron Pharmaceuticals

Completed

A Study to Evaluate the Effectiveness of Intravitreal Aflibercept in Patients With Diabetic Macular Edema and/or Macular Edema Secondary to Retinal Vein Occlusion, Which Either Have or Have Not Been Pretreated for Their Disease (AURIGA)

Macular Edema

Germany, Italy, Russian Federation, Taiwan, China, Egypt, France, Kuwait, Lebanon, Saudi Arabia, United Arab Emirates
GlaxoSmithKline

Completed

To Evaluate the Pharmacodynamics, Safety, and Pharmacokinetics of Pazopanib Drops in Adult Subjects With Neovascular AMD

Macular Degeneration

Italy, United States, Belgium, Australia
National Cancer Institute (NCI)
Indiana University School of Medicine

Active, not recruiting

Sunitinib for Advanced Thymus Cancer Following Earlier Treatment

Thymoma | Thymus Neoplasms

United States
National Cancer Institute (NCI)

Completed

VEGF Trap and Docetaxel in Treating Patients With Persistent or Recurrent Ovarian Epithelial Cancer, Primary Peritoneal Cancer, or Fallopian Tube Cancer

Fallopian Tube Cancer | Recurrent Ovarian Epithelial Cancer | Malignant Tumor of Peritoneum

United States
Bayer

Completed

A Study to Assess the Effectiveness of Aflibercept in Routine Clinical Practice in Patients With Diabetic Macular Oedema (DRAKO)

Macular Edema

United Kingdom
University of Zurich

Completed

VEGF-antagonism and Endothelial Function in Age-related Macular Degeneration (AMD)

Macular Degeneration

Switzerland
Greater Houston Retina Research

Completed

Rubeosis Anti-VEGF (RAVE) Trial for Ischemic Central Retinal Vein Occlusion

Ischemic Central Retinal Vein Occlusion

United States
Medical University of Warsaw

Unknown

The Search for Viral and Bacterial Etiology of Varicocele (ViBaVa)

Bacterial Infections | Varicocele | Viral Infection | Sonic Hedgehog Expression | VEGF Expression

Poland
Bayer
Regeneron Pharmaceuticals

Completed

Vascular Endothelial Growth Factor (VEGF) Trap-Eye: Investigation of Efficacy and Safety in Wet Age-Related Macular Degeneration (AMD) (VIEW 2)

Macular Degeneration

Belgium, Israel, Italy, Spain, Korea, Republic of, Switzerland, Germany, Portugal, Japan, France, Australia, Netherlands, India, Austria, Brazil, Poland, United Kingdom, Singapore, Hungary, Latvia, Mexico, Czech Republic, Colombia, Ar... and more
Institute of Cardiology, Warsaw, Poland

Completed

Vascular Endothelial Growth Factor (VEGF), Platelet Derived Growth Factor (PDGF), Hepatocyte Growth Factor (HGF) in Patients With Acute Coronary Syndrome (ACS)

Acute Coronary Syndrome

Poland
Retina Macula Institute
Allergan

Completed

Efficacy of an Intravitreal DEX Implant in Retinal Vein Occlusion Following Treatment With Anti-VEGF Injections.

Macular Edema | Retinal Vein Occlusion

United States
Fujian Cancer Hospital

Not yet recruiting

Serplulimab Combined With Anti-VEGF Antibody in Advanced Lung Adenocarcinoma

Lung Adenocarcinoma | PD-1 Inhibitor | Stage IV Non-small Cell Lung Cancer | VEGF
National Cancer Institute (NCI)
NCIC Clinical Trials Group; Cancer and Leukemia Group B; North Central Cancer... and other collaborators

Active, not recruiting

Chemotherapy With or Without Bevacizumab in Treating Patients With Stage IB, Stage II, or Stage IIIA Non-small Cell Lung Cancer That Was Removed By Surgery

Stage IB Lung Non-Small Cell Carcinoma AJCC v7 | Stage IIA Lung Non-Small Cell Carcinoma AJCC v7 | Stage IIB Lung Non-Small Cell Carcinoma AJCC v7 | Stage IIIA Lung Non-Small Cell Cancer AJCC v7

United States, Canada, Ireland, Peru, South Africa
The University of Hong Kong
National University Hospital, Singapore; Korea University; Kyungpook National... and other collaborators

Unknown

To Compare Anti-VEGF Monotherapy With Anti-VEGF and EPM Grid Laser Combination Therapy for Diabetic Macular Edema (END-DME)

Diabetic Macula Edema

China
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Recruiting

Combination Chemotherapy and Bevacizumab With the NovoTTF-100L(P) System in Treating Participants With Advanced, Recurrent, or Refractory Hepatic Metastatic Cancer

Metastatic Malignant Neoplasm in the Liver | Advanced Malignant Neoplasm | Refractory Malignant Neoplasm | Colorectal Carcinoma Metastatic in the Liver

United States
National Cancer Institute (NCI)

Completed

Ziv-aflibercept in Treating Patients With Locally Advanced, Unresectable, or Metastatic Gynecologic Soft Tissue Sarcoma

Fallopian Tube Cancer | Uterine Carcinosarcoma | Stage IV Ovarian Epithelial Cancer | Ovarian Sarcoma | Recurrent Uterine Sarcoma | Stage III Uterine Sarcoma | Stage IV Uterine Sarcoma | Recurrent Ovarian Epithelial Cancer | Stage III Ovarian Epithelial Cancer | Ovarian Carcinosarcoma | Female Reproductive... and other conditions

United States, Canada
National Cancer Institute (NCI)

Completed

Aflibercept in Treating Young Patients With Relapsed or Refractory Solid Tumors

Unspecified Childhood Solid Tumor, Protocol Specific

United States
Sudhalkar Eye Hospital

Not yet recruiting

Anti-VEGF Therapy Versus Dexamethasone Implant for DME

Clinically Significant Macular Edema Due to Diabetes Mellitus

Germany
Medical University of Vienna

Completed

Heavy Metals, Angiogenesis Factors and Osteopontin in Coronary Artery Disease (CAD)

Coronary Artery Disease | Ischemic Heart Disease | Heavy Metal Toxicity

Austria
National Cancer Institute (NCI)

Active, not recruiting

Testing the PD-1 Antibody, MK3475, Given With Ziv-aflibercept in Patients With Advanced Cancer

Sarcoma | Metastatic Renal Cell Carcinoma | Metastatic Melanoma | Recurrent Renal Cell Carcinoma | Recurrent Melanoma | Stage IV Renal Cell Cancer AJCC v8 | Metastatic Malignant Solid Neoplasm | Metastatic Colorectal Carcinoma | Stage IV Colorectal Cancer AJCC v8 | Clinical Stage IV Cutaneous Melanoma... and other conditions

United States, Canada
ECOG-ACRIN Cancer Research Group
National Cancer Institute (NCI)

Recruiting

Testing Pump Chemotherapy in Addition to Standard of Care Chemotherapy Versus Standard of Care Chemotherapy Alone for Patients With Unresectable Colorectal Liver Metastases: The PUMP Trial

Metastatic Malignant Neoplasm in the Liver | Metastatic Colorectal Carcinoma | Stage IV Colorectal Cancer AJCC v8 | Unresectable Colorectal Carcinoma

United States
Università degli Studi di Brescia
Ciro Costagliola; Francesco Semeraro; Roberto dell'Omo; Mario R Romano; Fabiana Aceto and other collaborators

Completed

VEGF and PEDF in Patients With Myopic Choroidal Neovascularization

Myopic Choroidal Neovascularization | VEGF Aqueous Level | PEDF Aqueous Level

Italy
M.D. Anderson Cancer Center
Novartis

Active, not recruiting

Sequential Two-agent Assessment in Renal Cell Carcinoma Therapy: The START Trial

Kidney Cancer

United States
Institute of Vision, Brasil

Unknown

VEGF Gene Association With Response to Neovascular Age-related Macular Degeneration With Anti-VEGF Agents

Macular Degeneration

Brazil

Search clinical trials for: Vascular endothelial growth factor (VEGF)

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