Search clinical trials for: orphan tumors

Total 16184 results

Russian Academy of Medical Sciences

Recruiting

MelPRO-0322 (CRISTINA Trial) [miCrobiome pRedIctS aPD1 effecTivnes In melaNoma pAtietns] (CRISTINA)

Melanoma Stage Iii | Melanoma, Skin

Russian Federation
Boundless Bio

Recruiting

Study of the RNR Inhibitor BBI-825 in Subjects With Tumors With Resistance Gene Amplifications (STARMAP)

Solid Tumor

United States
Tianjin Medical University Cancer Institute and...

Recruiting

Single-center, Prospective Study on the Identification and Delineation of Brain and Lung Tumors and At-Risk Organs, and Functional Testing of Surrounding Tissues Based on Dual-Energy CT

Image Quality and Contouring Accuracy of the Tumor in Radiotherapy

China
Nanjing First Hospital, Nanjing Medical University

Recruiting

Endostar Combined With SBRT and Envafolimab in the Treatment of Advanced Gastrointestinal Tumors

Gastrointestinal Neoplasms

China
Erasmus Medical Center
Hospices Civils de Lyon; Maastro Clinic, The Netherlands

Recruiting

Artificial Intelligence Prediction Tool in Thymic Epithelial Tumors (INTHYM)

Thymic Carcinoma | Thymoma | Thymic Epithelial Tumor | Thymoma and Thymic Carcinoma

Netherlands
Pasithea Therapeutics Corp.

Recruiting

PAS-004 in Patients With Advanced Solid Tumors

Advanced Solid Tumors | RAS Mutation | NF1 Mutation | RAF Mutation

United States
Seattle Children's Hospital
Children's Hospital of Philadelphia

Not yet recruiting

Efficacy and Safety of Phentermine/Topiramate in Youth With Hypothalamic Obesity

Craniopharyngioma | Hypothalamic Obesity | Hypothalamic Tumor

United States
Zealand University Hospital

Not yet recruiting

Physical Attendance Versus Telephone or Video Follow-up in Patients With Non-functioning Pituitary Tumors. (PITCARE)

Non-Functional Pituitary Adenoma
Dana-Farber Cancer Institute
World Cancer Research Fund International

Not yet recruiting

Exercise and Diet Interventions During Immunotherapy in Melanoma Patients

Skin Cancer | Melanoma (Skin) | Advanced Melanoma

United States
Iacopo Sardi

Recruiting

Evaluate the Role of Anthracycline After Radio Therapy in Patients With Glioblastoma (pGBM).

Glioblastoma

Italy
Regor Pharmaceuticals Inc.

Recruiting

A Phase I Study of RGT-419B in Patients With HR-Positive, HER2-Negative Advanced Breast Cancer or Other Solid Tumors

Breast Cancer | Advanced Solid Tumor

China
Fondazione Policlinico Universitario Agostino Gemelli...

Not yet recruiting

Spatial Profile of Tumors (PROST)

Solid Tumors

Italy
Numab Therapeutics AG

Recruiting

NM32-2668 in Adult Patients With Selected Advanced Solid Tumors

Renal Cell Carcinoma | Mesothelioma, Malignant | Adenocarcinoma of Lung | Triple Negative Breast Cancer | Endometrial Cancer | Fallopian Tube Carcinoma | Peritoneal Carcinoma | Leiomyosarcoma | Liposarcoma | Ovarian Carcinoma | Adenocarcinoma of the Stomach | Melanoma, Malignant | Adenocarcinoma - Gastroesophageal...

United States
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.

Recruiting

TQB2928 Injection Combined With Penpulimab in Treatment of Advanced Malignant Tumors.

Advanced Malignant Neoplasm

China
H. Lee Moffitt Cancer Center and Research Institute

Recruiting

Biomarker Driven Patient Selection Neoadjuvant Anti-PD1 or Combinations for Locoregionally Advanced Melanoma

Melanoma | Advanced Melanoma | Melanoma Stage IV | Melanoma Stage III

United States
Federal Research Institute of Pediatric Hematology...
University Medical Center, Kazakhstan

Recruiting

Abdominal Neuroblastoma Laparoscopic Surgery Risk Factors Stratification (ANLAP-R)

Neuroblastoma | Ganglioneuroblastoma | Ganglioneuroma

Russian Federation
Odense University Hospital
Aarhus University Hospital; University of Copenhagen; Aalborg University Hospital

Recruiting

Shared Decision Making in Melanoma Patients Receiving Adjuvant Therapy

Malignant Melanoma

Denmark
Beijng Immunoah Pharma Tech Co., Ltd.

Recruiting

Safety/Tolerability, PK and Efficacy of IMB071703 Injection in Patients With Advanced Solid Tumors

Recurrent or Metastatic, Advanced Solid Tumors

China
SUNHO（China）BioPharmaceutical CO., Ltd.

Not yet recruiting

A Clinical Trial to Evaluate Effect of IBD0333 in Patients With Advanced Malignant Tumors

MTD
Dong-A ST Co., Ltd.

Not yet recruiting

Clinical Trial to Investigate Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Efficacy of DA-4505 as a Single Agent and in Combination With Pembrolizumab in Adult Patients With Locally Advanced or Metastatic Solid Tumors

Locally Advanced or Metastatic Solid Tumors
NHS Grampian
University of Aberdeen

Recruiting

FCI in Post-operative Low Grade Gliomas

Glioma

United Kingdom
Aristotle University Of Thessaloniki

Not yet recruiting

Predictive Factors for Medullary Thyroid Cancer Aggressiveness (MYELO)

Medullary Thyroid Cancer

China, Switzerland, Spain, Greece, United States, Austria, Belgium, Brazil, Bulgaria, Colombia, Croatia, France, India, Iraq, Italy, Jordan, Morocco, Poland, Serbia, Slovakia, Thailand, Turkey, Ukraine, Vietnam
SystImmune Inc.

Recruiting

Open Label Study to Evaluate BL-M07D1 in HER2 Expressing Malignant Solid Tumors

Cervical Cancer | Ovarian Cancer | Endometrial Cancer | Urothelial Carcinoma | Biliary Tract Cancer

United States
Peking University First Hospital

Not yet recruiting

PET Imaging of 68Ga-Her2-affibody in Tumors With High Her2 Expression

Neoplasms

China
BioRay Pharmaceutical Co., Ltd.

Not yet recruiting

A Study of BRY805 in Participants With Advanced Solid Tumors

Advanced Solid Tumor

China
South Egypt Cancer Institute
Assiut University; Shefa Al-orman Children Cancer Hospital

Recruiting

Study of Wilms Tumors Among Patients of Shefa Al-Orman Children Cancer Hospital

Wilms Tumor

Egypt
3H (Suzhou) Pharmaceuticals Co., Ltd.

Not yet recruiting

A First-in-human Study of 3HP-2827 in Patients With Unresectable or Metastatic Solid Tumors With FGFR2 Alterations

Solid Tumors With FGFR2 Alterations, Adult

United States
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Sun Yat-sen University; The Third Affiliated Hospital of Guangzhou Medical... and other collaborators

Recruiting

AI-Assisted System for Accurate Diagnosis and Prognosis of Breast Phyllodes Tumors

Artificial Intelligence | Diagnosis | Phyllodes Breast Tumor | Multiomics | Prognostic Cancer Model

China
Pfizer

Recruiting

A Study of PF-07820435 as a Single Agent and in Combination in Participants With Advanced Solid Tumors

Melanoma | Neoplasms | Renal Cell Carcinoma | Non-small-cell Lung Cancer | Squamous Cell Carcinoma of the Head and Neck | Urothelial Carcinoma | Colorectal Carcinoma | Ovarian Carcinoma

United States, Japan, Puerto Rico
West China Hospital

Recruiting

Lactobacillus Reuteri Alleviates Oral Mucositis in Patients Undergoing Radiotherapy for Malignant Head and Neck Tumors

Oral Mucositis (Ulcerative) Due to Radiation

China
Medical University of Vienna

Recruiting

Uveal Melanoma - Comparative Study

Uveal Melanoma

Austria
The First Affiliated Hospital with Nanjing Medical...

Recruiting

Efficacy and Safety of TMZ Plus 6-MP in the Patients With Recurrent Glioblastoma

Cancer | Glioblastoma | Temozolomide

China
National Cancer Center, China

Recruiting

Lateral Pelvic Lymph Node Dissection for Rectal Neuroendocrine Neoplasms Undergoing Laparoscopic Total Mesenteric Excision

Rectal Neuroendocrine Neoplasm

China
Jasper Gerritsen
Massachusetts General Hospital; Universitaire Ziekenhuizen KU Leuven; University... and other collaborators

Recruiting

The RECSUR-study: Resection Versus Best Oncological Treatment for Recurrent Glioblastoma (ENCRAM 2302) (RECSUR)

Glioblastoma | Glioblastoma Multiforme | Recurrent Glioblastoma | Glioblastoma, IDH-wildtype | Glioblastoma Multiforme, Adult | Glioblastoma Multiforme of Brain | Astrocytoma of Brain | Astrocytoma, Malignant

United States, Germany, Netherlands, Switzerland, Belgium
Medical University of Vienna

Recruiting

Longitudinal Follow-Up of Patients Treated With Hypofractionated Stereotactic Photon Radiotherapy Due to Uveal Melanoma

Uveal Melanoma

Austria
Duke University

Not yet recruiting

Biobanking Upper Gastrointestinal Tumors to Evaluate Response (BURGER With BACON)

GastroEsophageal Cancer

United States
Cardenal Herrera University

Recruiting

Consequences on the Gait Pattern of Patients With Distal Femur Megaprostheses (IMU-DFM)

Distal Femoral Musculoskeletal Tumors

Spain
Chinese University of Hong Kong
Agilis Robotics Limited

Not yet recruiting

First-in-Human Trial of a Novel Endoluminal Robotic System for En-Bloc Resection of Bladder Tumours

Bladder Cancer
Bavarian Cancer Registry
Bavarian Association of Statutory Health Insurance Accredited Physicians

Not yet recruiting

Risk Factors for Neuroendocrine Neoplasms

Neuroendocrine Neoplasm of Lung | Neuroendocrine Neoplasm of Gastrointestinal Tract (Disorder)
Innovent Biologics (Suzhou) Co. Ltd.

Recruiting

A Study of IBI363 in Subjects With Advanced Solid Malignancies

Solid Tumors

United States
Azienda Ospedaliera di Perugia

Not yet recruiting

Impact of Anti PD-1 Therapy in Children, Adolescents and Young Adults (CAYA) Melanoma Patients (MELCAYA)

Advanced Melanoma | Early Melanoma

Italy, Sweden, France, Germany, Netherlands, Poland, Spain
Suzhou Zelgen Biopharmaceuticals Co.,Ltd

Not yet recruiting

Dose Escalation Study of ZG006 in Participants With Advanced Small Cell Lung Cancer or Neuroendocrine Carcinoma, Followed by Dose Expansion Study in Participants With Advanced Small Cell Lung Cancer

Small Cell Lung Cancer | Neuroendocrine Cancer

China
Latticon Antibody Therapeutics, Inc

Recruiting

A First-in-Human, Phase 1/2 Study of LAT010 in Patients With Advanced Solid Tumors (LIGHTSPEED-1) (LIGHTSPEED-1)

Advanced Solid Tumor

United States
Karolinska University Hospital

Recruiting

Resection or Ablation of Small Kidney Tumors (RESTART)

Kidney Cancer

Sweden
HRYZ Biotech Co.

Not yet recruiting

MASCT-I Combined With Doxorubicin and Ifosfamide for First-line Treatment of Advanced Soft Tissue Sarcoma

Leiomyosarcoma | Fibrosarcoma | Liposarcoma | Angiosarcoma | Synovial Sarcoma | Endometrial Stromal Sarcoma | Undifferentiated Pleomorphic Sarcoma | Epithelioid Sarcoma | Desmoplastic Small Round Cell Tumor | Malignant Peripheral Nerve Sheath Tumors | Pleomorphic Rhabdomyosarcoma

China
Xencor, Inc.

Recruiting

Phase 1, Safety and Tolerability Study of XmAb®541 in Advanced Solid Tumors

Testicular Germ Cell Tumor | Ovarian Cancer | Endometrial Cancer | Ovarian Germ Cell Tumor | Germ Cell Tumor

United States
The Netherlands Cancer Institute
Agenus Inc.

Recruiting

Pan-tumor Neoadjuvant Basket Study of Immune Check-point Inhibition and Novel Immuno-oncology Combinations (NEOASIS)

Resectable MMR-deficient Solid Tumors | Resectable MMR-proficient Solid Tumors

Netherlands
ANRS, Emerging Infectious Diseases

Not yet recruiting

Impact of Long-acting Injectable Cabotegravir for HIV PrEP in MSM in France. (CABOPrEP)

Prevention

France
Pure Biologics S.A.
Presage Biosciences

Recruiting

A Study of the Intratumoral Microdose Administration of PBA-0405 in Patients With Solid Tumors

Triple Negative Breast Cancer | Head and Neck Squamous Cell Carcinoma | Soft Tissue Sarcoma Adult

United States
Biond Biologics

Not yet recruiting

A Study of BND-35 in Participants With Advanced Solid Tumors

Cancer

Israel

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