Search clinical trials for: pharmacokinetic (PK)

Total 14168 results

AstraZeneca

Completed

Pharmacokinetic, Safety and Tolerability Study of Aclidinium/Formoterol Fixed Dose Combination and Formoterol in Patients With Moderate to Severe Chronic Obstructive Pulmonary Disease (COPD)

Chronic Obstructive Pulmonary Disease (COPD)

United States
Acorda Therapeutics

Completed

A Pharmacokinetic Study to Assess Dose Proportionality, Safety and Tolerability of Diazepam Nasal Spray in Healthy Adult Volunteers

Healthy

United States
Biotech Pharmaceutical Co., Ltd.

Unknown

Pharmacokinetics Study of Nimotuzumab in Patients With Solid Tumors

Solid Tumors

China
University of Turku

Completed

Population Pharmacokinetics of Dexmedetomidine in ICU Patients (Dex-Pop-PK)

Pharmacokinetics

Finland
Teva Branded Pharmaceutical Products R&D, Inc.

Completed

A Study to Assess the Pharmacokinetics, Safety, and Tolerability of Single and Multiple Doses of Rasagiline

Parkinson's Disease

United States
Ventrus Biosciences, Inc

Unknown

An Open-Label, Single- and Multi-Dose Pharmacokinetic (PK) Study of Oral Diltiazem and Topical Diltiazem Hydrochloride

Adult Subjects With Anal Fissures.

United States
The Miriam Hospital
Eunice Kennedy Shriver National Institute of Child Health and Human Development...

Unknown

Pharmacokinetics of Anti-TB Drugs in HIV/TB Co-infected Children in Ghana

HIV | Tuberculosis

Ghana
Javelin Pharmaceuticals

Completed

Study to Assess the Safety, Tolerability and Pharmacokinetic Profile of MNS075 (Intranasal Morphine)

Healthy

United States
Javelin Pharmaceuticals

Completed

Study to Compare the Pharmacokinetics of IV Diclofenac Sodium (2 Doses)Versus Oral Diclofenac Potassium

Healthy

United States
Pharmaxis

Completed

A Pharmacokinetic and Bioavailability Study of Mannitol for Inhalation Using Normal Subjects

Healthy Volunteers
Drugs for Neglected Diseases
University of Oxford; KEMRI-Wellcome Trust Collaborative Research Program

Completed

Intravenous and Oral Fosfomycin in Hospitalised Neonates With Clinical Sepsis (NeoFosfo)

Neonatal SEPSIS

Kenya
Novartis Pharmaceuticals

Completed

Study to Evaluate Treatment Compliance, Efficacy and Safety of an Improved Deferasirox Formulation (Granules) in Pediatric Patients (2-<18 Years Old) With Iron Overload

Transfusion-dependent Anemia

Egypt, Hungary, Turkey, United States, Bulgaria, Italy, Belgium, Russian Federation, Philippines, France, Malaysia, India, Oman, Panama, Lebanon, Thailand, Tunisia
Obstetrix Medical Group

Completed

Progesterone (17P, Makena®) for Prolongation of Pregnancy in Women With Preterm Rupture of the Membranes (PROM) (17PinPROM)

Preterm Delivery

United States
University of California, Los Angeles
Gilead Sciences; University of Cape Town; Desmond Tutu HIV Foundation

Completed

PK of TAF and TDF for PrEP in Pregnant and Postpartum Women (PrEP-PP PK)

Hiv

South Africa
Hoffmann-La Roche

Completed

A Pharmacokinetics (PK) Study to Investigate the Effect of Rifampin on PK of Vemurafenib (Zelboraf)

Malignant Melanoma, Neoplasms

United States, South Africa, Croatia, Brazil, Egypt
Robert Flavell, MD, PhD
Bristol-Myers Squibb; U.S. Army Medical Research Acquisition Activity

Recruiting

Magnetic Resonance (MR) Imaging With Hyperpolarized Bicarbonate (13C) to Measure Tissue pH in Prostate Cancer

Prostate Cancer | Localized Prostate Carcinoma

United States
The Aurum Institute NPC
Johns Hopkins University; University of California

Completed

Safety Tolerability DDI Short Course Treatment of LTBI Infection With High-dose Rifapentine and Isoniazid or Standard Isoniazid Preventive Therapy in HIV+ Patients (DOLPHIN & DOLPHIN TOO) (IMPAACT4TB)

HIV Infections | Respiratory Tract Infections

South Africa
Pakistan Institute of Living and Learning

Active, not recruiting

Integrated Mental Healthcare Plan for Management of Depression and Self-harm in Pakistan (PRIME-PK)

Depression | Self Harm

Pakistan
Lihir Medical Centre

Completed

PK PD Study of IDA and Azithromycin for NTDs ( ComboNTDs )

Trauma | Lymphatic Filariasis | Yaws

Papua New Guinea
University Hospital, Gasthuisberg

Completed

Evaluation of Adding Small Amounts of Oxygen to the CO2 Pneumoperitoneum Upon Pain and Inflammation

Pain | Inflammation

Belgium
AstraZeneca

Completed

A Study to Assess the Safety, Efficacy and Tolerability of AZD8233 Treatment in Participants With Hyperlipidaemia (SOLANO)

Hyperlipidaemia

Denmark, Netherlands, Spain, Czechia, United States, Slovakia, Hungary, Poland
M.D. Anderson Cancer Center
Myriad Genetic Laboratories, Inc.

Withdrawn

Correlation of Genomic Variation in Enzymes Responsible for Metabolism of Capecitabine With Drug Metabolism

Breast Cancer
The Aurum Institute NPC
Johns Hopkins University

Recruiting

Rifapentine and Isoniazid TB Preventive Therapy (3HP) for Children Taking Dolutegravir-based Antiretroviral Treatment (DOLPHIN KIDS) (DOLPHIN KIDS)

HIV | Tuberculosis

South Africa
Biogen

Completed

Peginterferon Beta-1a (BIIB017) Autoinjector Pharmacokinetic Study in Healthy Volunteers

Multiple Sclerosis | Healthy

United States
University of California, San Francisco

Completed

Drug Interaction Study Between Antimalarial and Anti-HIV Medications

HIV Infections | Malaria

United States
Nicklaus Children's Hospital f/k/a Miami Children...

Terminated

Liposomal Bupivacaine Pharmacokinetic Study After Median Sternotomy Incision Infiltration in a Pediatric Cardiac Surgery (CohortI-II)

Cardiac Conditions

United States
EMD Serono Research & Development Institute, Inc.
Merck KGaA, Darmstadt, Germany

Completed

Phase 1 Trial of MSC2490484A, an Inhibitor of a DNA-dependent Protein Kinase, in Combination With Radiotherapy

Advanced Solid Tumors

United States, Germany, Norway, Netherlands, Belgium, Denmark, Sweden, Switzerland
Celgene

Completed

Influence of Ketoconazole on the Pharmacokinetics of Romidepsin in Patients With Advanced Cancer

Hematologic Malignancy | Malignant Lymphoma

United States, United Kingdom
Medtronic Vascular

Completed

The ENDEAVOR Pharmacokinetic (PK) Registry: The Medtronic Endeavor Drug Eluting Coronary Stent System (ENDEAVOR PK)

Coronary Artery Disease

United States
Pfizer

Completed

A Single Dose Study In Japanese And Western Healthy Subjects To Investigate The Safety, Tolerability And Pharmacokinetics Of PF-04991532

Glucose Metabolism Disorders | Diabetes Mellitus, Type 2 | Diabetes Mellitus

United States
Celgene

Completed

Influence of Rifampin on the Pharmacokinetics of Romidepsin in Patients With Advanced Cancer

Hematologic Malignancy | Malignant Lymphoma

United States, United Kingdom
AstraZeneca

Completed

AZD7687 Multiple Ascending Dose Study

Overweight | Obese

United Kingdom
Pfizer

Completed

Relative Bioavailability Study

Healthy

United States
Helsinki University Central Hospital

Active, not recruiting

Effect of Aerosol Filtering on Infectious Diseases in Day Care

Diarrhea | Upper Respiratory Tract Infection

Finland
Hasselt University
KU Leuven; Vrije Universiteit Brussel

Completed

Validation Study CARES (OPSA-PK)

Cancer

Belgium
Health Ever Bio-Tech Co., Ltd.

Unknown

Pharmacokinetics of MCS in Healthy Volunteers (MCS-2-US-pk)

Healthy
Sequella, Inc.

Completed

Safety, Tolerability And Pharmacokinetics Study Of Single Doses Of PNU-100480 In Healthy Adults

Tuberculosis

United States
Amgen

Completed

Compare Actions in Healthy Volunteer of 50 mg Etanercept Injection Using an Auto-injector Device and Manual Injection

Healthy Men and Women
Hektoen Institute for Medical Research
National Institute of Mental Health (NIMH)

Completed

Transgender Youth and PrEP: PK, Safety, Uptake & Adherence - PK Study

HIV/AIDS | Gender | Behavior and Behavior Mechanisms

United States
PharmaEssentia

Completed

The Pharmacokinetics of P1101 + Ribavirin in Interferon Treatment-Naïve Subjects With Chronic Hepatitis C Virus (HCV) Genotype 2 Infection

Hepatitis C, Chronic

Taiwan
Pfizer

Completed

Safety And Pharmacokinetics Study Of PF-04287881 In Healthy Adults

Respiratory Tract Infections

United States
Merck Healthcare KGaA, Darmstadt, Germany, an affiliate...

Completed

Effect of Food on Peposertib PK

Healthy

Germany
Alexza Pharmaceuticals, Inc.

Completed

Staccato Fentanyl Single and Multidose PK

Breakthrough Pain

United States
The HIV Netherlands Australia Thailand Research...
Radboud University Medical Center; Chulalongkorn University; amfAR, The Foundation... and other collaborators

Completed

Abacavir and Lamivudine PK in Children

HIV

Thailand
Mayo Clinic
National Institute of Neurological Disorders and Stroke (NINDS)

Recruiting

Long-term Effects of COVID-19

COVID-19 | SAR-CoV-2

United States
Michael Hoelscher
Radboud University Medical Center; University College, London; University of...

Recruiting

PanACEA - STEP2C -01

Pulmonary Tuberculosis | Other Specified Pulmonary Tuberculosis

Gabon, South Africa, Tanzania, Malawi, Uganda, Mozambique
Radboud University Medical Center
Merck Sharp & Dohme LLC; ZonMw: The Netherlands Organisation for Health Research...

Recruiting

Study on PhArmacokinetics of First liNe Antiretrovirals in Healthy Breastfeeding Volunteers (PANNA-B PK)

Hiv

Netherlands
Brugmann University Hospital

Recruiting

Does the Thrombin Generation Test Performed During the Pharmacokinetic Profile of the Substitutive Factor VIII Bring Benefits to the Personalized Treatment of Pediatric Patients and Adult Hemophilia A Patients Under Prophylaxis ?

Hemophilia

Belgium
Alebund Pty Ltd

Completed

A Safety, Tolerability, and Pharmacokinetics Study of AP303 in Healthy Subjects

Healthy Subjects

Australia
Philip Morris Products S.A.

Completed

Nicotine Pharmacokinetics of THS Single Use of a Regular or a Menthol Stick Compared to CIG

Smoking, Tobacco

United Kingdom

Search clinical trials for: pharmacokinetic (PK)

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