Search clinical trials for: temodar

Total 367 results

Dana-Farber Cancer Institute
National Cancer Institute (NCI); Boston Children's Hospital; Celgene Corporation

Completed

Thalidomide and Temozolomide in Relapsed or Progressive CNS Disease or Neuroblastoma

Neuroblastoma | Central Nervous System Tumor, Pediatric

United States
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Irinotecan and Temozolomide in Treating Young Patients With Recurrent Neuroblastoma

Neuroblastoma

United States, Canada, Australia
Exelixis

Completed

Safety Study of XL184 (Cabozantinib) in Combination With Temozolomide and Radiation Therapy in the Initial Treatment of Adults With Glioblastoma

Glioblastoma | Gliosarcoma | Giant Cell Glioblastoma

United States
Duke University
Pfizer

Completed

Ph. II Treatment of Adults w Primary Malignant Glioma w Irinotecan + Temozolomide

Glioblastoma

United States
Duke University
Schering-Plough; Keryx / AOI Pharmaceuticals, Inc.

Completed

Ph I 5-day Temozolomide + O6-BG in Treatment of Pts w Recurrent / Progressive GBM

Glioblastoma | Gliosarcoma

United States
Duke University
National Institutes of Health (NIH); Keryx / AOI Pharmaceuticals, Inc.

Completed

Ph. II Temozolomide + O6-BG in Treatment of Pts w Temozolomide-Resistant Malignant Glioma

Glioblastoma Multiforme | Anaplastic Glioma

United States
National Cancer Institute (NCI)

Completed

ABT-888 and Temozolomide in Treating Young Patients With Recurrent or Refractory CNS Tumors

Recurrent Childhood Medulloblastoma | Recurrent Childhood Ependymoma | Childhood Atypical Teratoid/Rhabdoid Tumor | Childhood Choroid Plexus Tumor | Childhood Craniopharyngioma | Childhood Ependymoblastoma | Childhood Grade I Meningioma | Childhood Grade II Meningioma | Childhood Grade III Meningioma | Childhood High-grade Cerebellar Astrocytoma and other conditions

United States
National Cancer Institute (NCI)

Completed

Aflibercept, Radiation Therapy, and Temozolomide in Treating Patients With Newly Diagnosed or Recurrent Glioblastoma Multiforme, Gliosarcoma, or Other Malignant Glioma

Adult Anaplastic Astrocytoma | Adult Anaplastic Oligodendroglioma | Adult Giant Cell Glioblastoma | Adult Glioblastoma | Adult Gliosarcoma | Adult Mixed Glioma | Recurrent Adult Brain Tumor

United States
Duke University
Genentech, Inc.; Schering-Plough

Completed

Avastin in Combination With Radiation (XRT) & Temozolomide, Followed by Avastin, Temozolomide and Irinotecan for Glioblastoma (GBM) and Gliosarcomas

Glioblastoma | Brain Tumor | Gliosarcoma

United States
National Cancer Institute (NCI)

Completed

Temsirolimus, Irinotecan Hydrochloride, and Temozolomide in Treating Younger Patients With Relapsed or Refractory Solid Tumors

Unspecified Childhood Solid Tumor, Protocol Specific

United States, Canada
Katy Peters
Genentech, Inc.

Completed

Avastin/Temozolomide/Irinotecan for Unresectable/Multifocal Glioblastoma Multiforme

Glioblastoma Multiforme | Gliosarcoma

United States
Patrick Y. Wen, MD
Massachusetts General Hospital; University of Pennsylvania; Brigham and Women... and other collaborators

Completed

Dose-Intense Temozolomide in Recurrent Glioblastoma

Glioblastoma | Gliosarcoma

United States
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Temozolomide in Treating Young Patients With Refractory or Recurrent Leukemia

Leukemia

Canada, United States
Northwestern University
Millennium Pharmaceuticals, Inc.

Completed

Presurgery Bortezomib for Recurrent Malignant Gliomas Followed by Postop Bortezomib & Temozolomide

Brain and Central Nervous System Tumors

United States
Marmara University
Schering-Plough

Completed

Efficacy of Protracted Temozolomide in Patients With Progressive High Grade Glioma

Glioblastoma | Astrocytoma | Oligodendroglioma | Brain Tumor, Recurrent

Turkey
Isarna Therapeutics GmbH

Completed

Phase IIb Clinical Trial With TGF-β2 Antisense Compound AP 12009 for Recurrent or Refractory High-grade Glioma

Glioblastoma | Anaplastic Astrocytoma

Germany, Austria, Georgia, India, Israel, Russian Federation
Katy Peters
GlaxoSmithKline; Schering-Plough

Completed

Ph I Oral Topotecan and Temozolomide for Patients With Malignant Gliomas

Glioblastoma | Gliosarcoma | Anaplastic Astrocytoma

United States
National Cancer Institute (NCI)

Completed

Temozolomide and O6-Benzylguanine in Treating Children With Recurrent Brain Tumors

Recurrent Childhood Medulloblastoma | Recurrent Childhood Ependymoma | Childhood Choroid Plexus Tumor | Childhood Craniopharyngioma | Childhood Ependymoblastoma | Childhood Grade I Meningioma | Childhood Grade II Meningioma | Childhood Grade III Meningioma | Childhood High-grade Cerebellar Astrocytoma | Childhood High-grade Cerebral Astrocytoma and other conditions

United States
California Pacific Medical Center Research Institute

Completed

Biochemotherapy and Bevacizumab Followed by Consolidation Therapy With Ipilimumab for Metastatic Melanoma (BBI)

Metastatic Melanoma

United States
National Cancer Institute (NCI)

Completed

Erlotinib and Temozolomide With Radiation Therapy in Treating Patients With Glioblastoma Multiforme or Other Brain Tumors

Adult Giant Cell Glioblastoma | Adult Glioblastoma | Adult Gliosarcoma

United States
Duke University
Genentech, Inc.

Completed

Ph II Bev + Either Temozolomide/Etoposide for GBM Pts Who Have Failed Bev + Irinotecan

Glioblastoma | Gliosarcoma

United States
Duke University
Bayer; Schering-Plough

Completed

Ph. 2 Sorafenib + Protracted Temozolomide in Recurrent GBM

Recurrent Glioblastoma Multiforme

United States
Katy Peters
Merck Sharp & Dohme LLC; Genentech, Inc.

Completed

Suberoylanilide Hydroxamic Acid (SAHA), Bevacizumab, Daily Temozolomide for Recurrent Malignant Gliomas

Glioblastoma | Brain Tumor

United States
Duke University
Pharmacia; Keryx / AOI Pharmaceuticals, Inc.

Completed

Ph. I Temozolomide + O6-BG + Irinotecan in Treatment of Pts w Recurrent / Progressive Cerebral Anaplastic Gliomas

Glioblastoma | Gliosarcoma

United States
National Cancer Institute (NCI)

Completed

Erlotinib and Temozolomide in Treating Young Patients With Recurrent or Refractory Solid Tumors

Recurrent Childhood Medulloblastoma | Recurrent Childhood Ependymoma | Recurrent Neuroblastoma | Recurrent Osteosarcoma | Recurrent Childhood Rhabdomyosarcoma | Previously Treated Childhood Rhabdomyosarcoma | Recurrent Childhood Soft Tissue Sarcoma | Recurrent Childhood Malignant Germ Cell Tumor | Recurrent... and other conditions

United States
Duke University
Genentech, Inc.; Schering-Plough

Completed

Bevacizumab in Combination With Metronomic Temozolomide for Recurrent Malignant Glioma

Glioblastoma Multiforme

United States
Duke University
Genentech, Inc.; Schering-Plough

Completed

Avastin in Combination With Temozolomide for Unresectable or Multifocal GBMs and Gliosarcomas

Glioblastoma | Gliosarcoma

United States
Instituto Nacional de Cancerologia de Mexico

Completed

Whole Brain Radiotherapy With or Without Temozolomide at Daily Fixed-dose for Brain Metastases Treatment

Brain Neoplasms

Mexico
National Cancer Institute (NCI)

Completed

Vorinostat and Temozolomide in Treating Young Patients With Relapsed or Refractory Primary Brain Tumors or Spinal Cord Tumors

Recurrent Childhood Medulloblastoma | Recurrent Childhood Ependymoma | Childhood Atypical Teratoid/Rhabdoid Tumor | Extra-adrenal Paraganglioma | Childhood Choroid Plexus Tumor | Childhood Craniopharyngioma | Childhood Ependymoblastoma | Childhood Grade I Meningioma | Childhood Grade II Meningioma | Childhood... and other conditions

United States, Canada
Sanofi

Completed

A Study of XL765 (SAR245409) in Combination With Temozolomide With and Without Radiation in Adults With Malignant Gliomas

Glioblastoma Multiforme | Malignant Gliomas | Mixed Gliomas

United States
National Cancer Institute (NCI)

Completed

Temsirolimus, Temozolomide, and Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma Multiforme

Adult Giant Cell Glioblastoma | Adult Glioblastoma | Adult Gliosarcoma

United States
Duke University
Schering-Plough

Completed

PH I Addition of Farnesyl Transferase Inhibitor to Temozolomide for Pts w Gr 3 & 4 Malignant Gliomas

Glioblastoma | Gliosarcoma | Anaplastic Astrocytoma

United States
National Cancer Institute (NCI)

Completed

Temozolomide and Thalidomide in Treating Patients With Brain Metastases Secondary to Melanoma

Recurrent Melanoma | Stage IV Melanoma | Tumors Metastatic to Brain

United States
M.D. Anderson Cancer Center

Completed

Cisplatin, Temozolomide, Abraxane, With Interleukin-2 and Interferon for Metastatic Melanoma (BCAA)

Melanoma

United States
David Peereboom
National Cancer Institute (NCI)

Completed

Radiation Therapy, Temozolomide, and Erlotinib in Treating Patients With Newly Diagnosed Glioblastoma Multiforme

CNS Tumor, Adult

United States
Abbott

Completed

To Evaluate the Safety of Veliparib in Combination With Temozolomide in Subjects With Solid Tumors

Solid Tumor Cancers

United States
Annick Desjardins
Bristol-Myers Squibb

Withdrawn

Ph. I Dasatinib/Protracted Temozolomide in Recurrent Malignant Glioma

Glioma | Glioblastoma Multiforme | Gliosarcoma | Anaplastic Astrocytoma | Anaplastic Oligodendroglioma

United States
Columbia University
Celgene Corporation; Schering-Plough

Unknown

Phase I Dose-Escalation Study Of Azacitidine In Combination With Temozolomide

Soft Tissue Sarcoma | Mesothelioma

United States
University of Florida

Terminated

Study of Temozolomide to Treat Newly Diagnosed Brain Metastases

Brain Metastases

United States
The University of Texas Health Science Center at...
National Cancer Institute (NCI); Cancer Therapy and Research Center, Texas

Completed

Chemotherapy in Treating Patients With Advanced Solid Tumors

Unspecified Adult Solid Tumor, Protocol Specific

United States
Ludwig-Maximilians - University of Munich
Deutsche Krebshilfe e.V., Bonn (Germany)

Completed

Usefulness of Therapy Monitoring by Means of [(18)F]Fluoroethyltyrosine-Positron Emission Tomography (FET-PET) in Glioblastoma Multiforme Patients

Glioblastoma Multiforme

Germany
M.D. Anderson Cancer Center

Completed

Aerosol L9-NC and Temozolomide in Ewing's Sarcoma

Ewing's Sarcoma

United States
M.D. Anderson Cancer Center
Aventis Pharmaceuticals

Completed

Taxotere/Temodar/Cisplatin Study in Melanoma Patients

Metastatic Melanoma

United States
Tufts Medical Center

Terminated

Safety Study of High Dose Temozolomide to Treat Relapsed/Refractory Central Nervous System (CNS) Malignancy (CN-306)

Neoplasm Metastasis | Central Nervous System Neoplasms

United States
Mt. Sinai Medical Center, Miami
Northern California Melanoma Center

Completed

Temozolomide Plus Bevacizumab in Patients With Metastatic Melanoma Involving the Central Nervous System (MEL0107)

Melanoma

United States
Myrexis Inc.

Completed

Verubulin, Radiation Therapy, and Temozolomide to Treat Patients With Newly Diagnosed Glioblastoma Multiforme

Glioblastoma Multiforme

United States
M.D. Anderson Cancer Center
Schering-Plough; Enzon Pharmaceuticals, Inc.

Terminated

DepoCyt Plus Temozolomide in Patients With Neoplastic Meningitis

Neoplastic Meningitis

United States
Keryx / AOI Pharmaceuticals, Inc.

Terminated

A Phase II Study of Temozolomide and O6-Benzylguanine (O6-BG) in Patients With Temozolomide-Resistant Anaplastic Glioma

Glioma | Astrocytoma | Oligoastrocytoma | Oligodendroglioma

United States
M.D. Anderson Cancer Center

Terminated

Dietary Methionine Restriction Plus Temozolomide for Recurrent GBM

Glioblastoma Multiforme

United States
M.D. Anderson Cancer Center

Completed

6-TG, Capecitabine and Celecoxib Plus TMZ or CCNU for Anaplastic Glioma Patients

Brain Cancer | Glioblastoma Multiforme | Anaplastic Glioma of Brain

United States

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