Search clinical trials for: therapeutic vaccine

Total 21967 results

Genexine, Inc.

Unknown

Phase 2 Clinical Trial to Evaluate the Safety and Efficacy of Plasmid DNA Therapeutic Vaccine(GX-188E)

Cervical Intraepithelial Neoplasia

Korea, Republic of, Estonia, Ukraine
Genexine, Inc.

Completed

Dose-finding, Safety Study of Plasmid DNA Therapeutic Vaccine to Treat Cervical Intraepithelial Neoplasia

Cervical Intraepithelial Neoplasia

Korea, Republic of
Genexine, Inc.

Unknown

Safety and Efficacy of GX-188E DNA Therapeutic Vaccine Administered by Electroporation After Observation (GX-188E)

Cervical Intraepithelial Neoplasia 3

Korea, Republic of
National Institute of Allergy and Infectious Diseases...

Completed

Safety and Immune Response to a Prime-Boost Vaccination Schedule in HIV-infected Patients

HIV

United States
UNC Lineberger Comprehensive Cancer Center
National Cancer Institute (NCI); Susan G. Komen Breast Cancer Foundation

Terminated

Vaccine Therapy, Trastuzumab, and Vinorelbine in Treating Women With Locally Recurrent or Metastatic Breast Cancer

Breast Cancer

United States
Dendreon

Completed

Sequencing of Sipuleucel-T and ADT in Men With Non-metastatic Prostate Cancer

Prostate Cancer | Prostatic Neoplasm | Prostatic Adenocarcinoma

United States
Chang Gung Memorial Hospital

Completed

Hepatitis B Vaccine in Chronic Hepatitis B Patients With Low Serum HBsAg

Chronic Hepatitis B

Taiwan
MabVax Therapeutics, Inc.

Completed

Trivalent Ganglioside Vaccine With Immunological Adjuvant or Immunological Adjuvant Alone in Metastatic Sarcoma Patients Who Are Rendered Disease Free

Sarcoma

United States
Bionor Immuno AS
Celgene Corporation

Completed

Safety and Efficacy of Romidepsin and the Therapeutic Vaccine Vacc-4x for Reduction of the Latent HIV-1 Reservoir (REDUC)

HIV I Infection

Denmark
Abivax S.A.

Completed

Clinical Efficacy of ABX203 Therapeutic Vaccine in HBeAg Negative Patients With Chronic Hepatitis B

Chronic Hepatitis B

New Zealand, Australia
Opexa Therapeutics, Inc.

Completed

Dose-Escalation Study of T Cell Vaccine in Multiple Sclerosis (DES)

Multiple Sclerosis, Relapsing-Remitting | Multiple Sclerosis, Secondary Progressive

United States
National Institute of Allergy and Infectious Diseases...

Completed

Therapeutic HIV Vaccine and Interleukin-2 to Increase the Immune System's Response to HIV

HIV Infections

United States
Genticel

Completed

Phase II Study of HPV Therapeutic Vaccine in HPV Infected Women With Normal Cytology or ASCUS/LSIL (RHEIA-VAC)

Genital Infection Viral | HUMAN PAPILLOMA VIRUS

Belgium, Spain, Finland, France, United Kingdom, Germany, Netherlands
Institut National de la Santé Et de la Recherche...

Completed

Efficacy of Bilhvax in Association With Praziquantel for Prevention of Clinical Recurrences of Schistosoma Haematobium (Bilhvax3)

Urinary Schistosomiasis | Schistosoma Haematobium

Senegal
Novartis Vaccines

Completed

Phase 2, Observer-Blind, Placebo-Controlled, Randomized, Multi-Center Extension Study to Evaluate the Safety and Immunogenicity of a Booster Dose of a MenABCWY Vaccine Administered 24 Months Following the Primary Series to Adolescents and Young Adults Who Participated in V102_03 (NCT01272180)

Meningococcal Disease

United States, Poland
University of Arkansas
National Cancer Institute (NCI)

Completed

A Phase I Clinical Trial of an HPV Therapeutic Vaccine

Human Papillomavirus

United States
University of Missouri-Columbia

Withdrawn

Therapeutic Treatment With Human Papillomavirus Quadrivalent Vaccine for Recurrent Respiratory Papillomatosis

Recurrent Respiratory Papillomatosis

United States
BTG International Inc.
Encorium

Terminated

Safety and Efficacy Study of Angiotensin Therapeutic Vaccine in Subjects With Mild to Moderate Hypertension

Hypertension | Cardiovascular Disease

United Kingdom
Recombio SL
Eurofarma Laboratorios S.A.; Laboratorio Elea Phoenix S.A.; Innogene Kalbiotech... and other collaborators

Unknown

Immunotherapy With Racotumomab in Advanced Lung Cancer

NSCLC | Lung Cancer, Non-small Cell

Brazil, Indonesia, Argentina, Cuba, Philippines, Singapore, Thailand
French National Agency for Research on AIDS and...
GlaxoSmithKline

Terminated

Lamivudine and Therapeutic Vaccine Evaluation in Senegalese Patients With Chronic Hepatitis B Infection (ANRS 12100 HEPADAK-2)

Hepatitis B

Senegal
Celldex Therapeutics

Completed

A Study of CDX-1401 in Patients With Malignancies Known to Express NY-ESO-1

Advanced Malignancies

United States
Sharon Riddler
National Institute of Allergy and Infectious Diseases (NIAID)

Completed

Autologous Dendritic Cell Vaccine in HIV1 Infection

HIV Infections

United States
Pfizer

Completed

A Trial to Assess the Lot Consistency, Safety, Tolerability and Immunogenicity of Bivalent rLP2086 Vaccine When Given to Healthy Subjects Aged ≥10 to <19 Years

Meningococcal Vaccine

United States, Canada, Finland, Italy, Poland, United Kingdom, Czech Republic, Germany
Centers for Disease Control and Prevention, China
Beijing Ditan Hospital; National Institutes for Food and Drug Control, China

Unknown

Clinical Trial of Recombinant Adenovirus Type 5 AIDS Vaccine

Acquired Immunodeficiency Syndrome

China
Sanofi Pasteur, a Sanofi Company

Terminated

Study of a Multi-Antigen Therapeutic Vaccine in Patients With Metastatic Melanoma

Melanoma | Cancer

Canada, United States
Opexa Therapeutics, Inc.

Terminated

Open Label Extension of Prior TERMS Study to Treat Relapsing Forms of Multiple Sclerosis (OLTERMS)

Clinically Isolated Syndrome | Multiple Sclerosis, Relapsing-Remitting

United States
Barbara Ensoli, MD
Italian Ministry of Foreign Affairs - General Direction for Cooperation and...

Completed

A Phase Il of a Therapeutic, Recombinant, Biologically Active HIV-1 Tat Protein Vaccine in HIV-Infected, Anti-Tat Negative, ARV-Treated Adult Volunteers (ISS T-003)

HIV Infections

South Africa
Barbara Ensoli, MD

Completed

Immunogenicity and Safety Trial of the HIV-1 Tat Vaccine (ISS T-002)

HIV Infections

Italy
Barbara Ensoli, MD

Completed

Observational Study on Anti-Tat Immune Response in HIV-1-infected Asymptomatic Adult Subjects (ISS OBS T-003)

HIV Infections

Italy
Rabih Said
Agenus Inc.

Withdrawn

Pilot Study to Evaluate the Effects of a Vaccine (HSPPC-96) Combined With Ipilimumab in Patients With Advanced Melanoma

Melanoma

United States
Michael Morse, MD
National Cancer Institute (NCI)

Completed

Vaccine Therapy in Treating Patients With Liver or Lung Metastases From Colorectal Cancer

Colorectal Cancer | Metastatic Cancer

United States
Laboratorio Pablo Cassará S.R.L.
National Council of Scientific and Technical Research, Argentina; Fundacion... and other collaborators

Unknown

Phase II/III Clinical Study CSF470 Plus BCG Plus GM-CSF vs IFN Alpha 2b in Stage IIB, IIC and III Melanoma Patients

Cutaneous Melanoma

Argentina
Second Military Medical University
Zhejiang Cancer Hospital; Changhai Hospital; First People's Hospital of Hangzhou and other collaborators

Unknown

Trial of Antigen Pulsed Dendritic Cells (APDC) in Metastatic Colorectal Cancer

Metastatic Colorectal Cancer
Bioven Europe

Terminated

A Randomized Trial to Study the Safety and Efficacy of EGF Cancer Vaccination in Late-stage (IIIB/IV) Non-small Cell Lung Cancer Patients (NSCLC)

Carcinoma, Non-Small-Cell Lung

United Kingdom
University Hospital Erlangen

Completed

Vaccine Therapy in Treating Patients With Stage III or Stage IV Melanoma

Melanoma (Skin)

Germany
ReiThera Srl
University of Oxford

Completed

Study of a Novel Therapeutic Vaccine for Hepatitis C Virus

Hepatitis C

United Kingdom
GlobeImmune

Completed

Safety and Efficacy of the Therapeutic Vaccine GI-4000 in Combination With Gemcitabine Versus Placebo for the Treatment of Non-metastatic, Post-resection Pancreas Cancer

Pancreas Cancer

United States, India
Immunomic Therapeutics, Inc.

Completed

A Safety and Immunogenicity Phase IC Study of CryJ2 -DNA-LAMP Plasmid Vaccine for Assessment of Intradermal (ID) Route of Administration Using the Biojector 2000 Device

Allergic Rhinitis

United States
Pfizer

Withdrawn

Safety And Efficacy Study Of CP-675,206 In HIV-Infected Patients

Human Immunodeficiency Virus
National Institute of Allergy and Infectious Diseases...

Completed

A Study of the Safety and Effectiveness of an HIV Vaccine for HIV-Positive Patients Receiving Anti-HIV Drugs for at Least 2 Years

HIV Infections

United States
Dartmouth-Hitchcock Medical Center
National Cancer Institute (NCI)

Completed

Vaccine Therapy in Treating Patients With Stage III or Stage IV Melanoma

Melanoma (Skin)

United States
Hopital Foch
Saint-Louis Hospital, Paris, France; INSERM UMR912-SE4S, Marseille, France

Completed

Representations and Acceptability of HIV Therapeutic Vaccine in a Cohort of HIV-1 Infected Outpatients Followed at Hospital (RAVVIH)

HIV

France
National Cancer Institute (NCI)

Terminated

Neoadjuvant Intravesical Vaccine Therapy in Treating Patients With Bladder Carcinoma Who Are Undergoing Cystectomy

Stage III Bladder Cancer | Stage IV Bladder Cancer | Recurrent Bladder Carcinoma | Bladder Adenocarcinoma | Bladder Squamous Cell Carcinoma | Bladder Urothelial Carcinoma | Stage I Bladder Cancer | Stage II Bladder Cancer

United States
Abramson Cancer Center of the University of Pennsylvania
National Cancer Institute (NCI)

Completed

Vaccine Therapy in Treating Patients Who Are Undergoing Surgery for Ductal Carcinoma In Situ of the Breast

Breast Cancer

United States
Robert L. Murphy
National Institute of Allergy and Infectious Diseases (NIAID); Merck Sharp... and other collaborators

Completed

Therapeutic Intensification Plus Immunomodulation to Decrease the HIV-1 Viral Reservoir (EraMune02)

HIV Infection

United States
Vaccinex Inc.
PPD

Completed

Evaluation of Safety, Tolerability, PK & PD of Intravenous VX15/2503 in Patients With Advanced Solid Tumors

Solid Tumors

United States
Biogen
Acorda Therapeutics

Completed

A Pharmacokinetics (PK) and Safety Study of Oral Fampridine-PR 10 mg in Chinese, Japanese, and Caucasian Adult Healthy Volunteers

Healthy

Hong Kong, Australia
GlobeImmune

Completed

Safety and Efficacy of the Therapeutic Vaccine GI-5005 Combined With Pegylated Interferon Plus Ribavirin Standard of Care Therapy Versus Standard of Care Alone in Patients With Genotype 1 Chronic Hepatitis C Infection

Genotype 1 Chronic Hepatitis C

United States
University of Southern California
National Cancer Institute (NCI)

Terminated

Vaccine Therapy Followed by Biological Therapy in Treating Patients With Stage III or Stage IV Melanoma

Melanoma (Skin)

United States
Immunomic Therapeutics, Inc.

Completed

A Safety and Immunogenicity Phase I Study of CryJ2-DNA-Lysosomal Associated Membrane Protein (CryJ2 -DNA-LAMP) Plasmid

Allergic Rhinoconjunctivitis

United States

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