Search clinical trials for: Proton Pump Inhibitors

Total 68001 results

AstraZeneca
Parexel

Completed

Study to Assess the Effect of Food and Acid Reducing Agents on the Absorption of Capivasertib in Healthy Participants

Solid and Hematological Malignancies

Germany
GlaxoSmithKline

Completed

GSK1325756 Relative Bioavailability Study in Healthy Elderly Subjects

Pulmonary Disease, Chronic Obstructive

United States
Fundación Pública Andaluza para la Investigación...

Unknown

Response to Oral Lansoprazole of Inorganic Pyrophosphate Levels in Patients With Grönblad-Stranberg Disease (Pseudoxanthoma Elasticum) (FIMPXE2016-01)

Grönblad-Stranberg Disease (Pseudoxanthoma Elasticum)

Spain
Radboud University Medical Center
Merck Sharp & Dohme LLC

Completed

Pharmacokinetic Study of the HCV Protease Inhibitor Bo-cePRevir and the Proton Pump Inhibitor OMeprazOle (PROMO) (PROMO)

HCV Infections | Gastric Acid-related Disorders

Netherlands
Newcastle-upon-Tyne Hospitals NHS Trust
Newcastle University

Completed

Pilot Trial Of Omeprazole in Idiopathic Pulmonary Fibrosis (IPF) (PPIPF)

Idiopathic Pulmonary Fibrosis

United Kingdom
Genentech, Inc.

Completed

A Study to Evaluate the Effect of a Proton-Pump Inhibitor (Rabeprazole) on the Relative Bioavailability of Cobimetinib in Healthy Participants

Healthy Volunteer
AstraZeneca

Completed

Safety and Efficacy Study to Determine Anti-Asthmatic Effect of Esomeprazole Magnesium; Nexium Reflux Asthma (RELAX)

Asthma | GERD

United States, Bulgaria, Czech Republic, France, Italy, Poland, Germany, Canada, Hungary, Slovakia, Argentina, Mexico, Portugal, Switzerland
Zealand University Hospital

Terminated

The Clinical Significance of Acid Rebound in Functional Dyspepsia (CLARIFY)

Functional Dyspepsia

Denmark
Eisai Inc.

Completed

Maintenance Intermittent Therapy for Symptomatic GERD Patients

Gastroesophageal Reflux Disease

United States
University of Western Ontario, Canada

Completed

Evaluation of Methods for the Determination of Chromogranin A in Routine Blood Samples

Neuroendocrine Carcinoma (Carcinoid)

Canada
David A. Johnson, MD
AstraZeneca

Completed

Gastroesophageal Reflux Disease (GERD)/Nighttime Heartburn and Driving Performance

GERD

United States
Inje University

Withdrawn

Double-dose Rabeprazole Accelerates and Sustains the Control of Symptoms in Patients With NERD (DRNERD)

Gastroesophageal Reflux Disease

Korea, Republic of
AstraZeneca

Completed

Reflux Esophagitis Phase III Study (Initial Treatment)

Reflux Esophagitis

Japan
Nantes University Hospital

Completed

Comparison of Antisecretory Effect of a Single Dose of Rabeprazole 20 mg and Omeprazole 20 mg in Obese Subjects (Oberab)

Gastroesophageal Reflux

France
Dr. Reddy's Laboratories Limited

Completed

Bioequivalence Study of Omeprazole Magnesium 20 mg DR Capsule Under Fed Conditions

Healthy

India
Eisai Inc.

Completed

E3810-A001-312: Efficacy and Safety of 10 mg Rabeprazole for Treating Heartburn in Frequent Sufferers

Heartburn

United States
Zhongshan Hospital Xiamen University

Unknown

Camrelizumab Combined With Apatinib in the Treatment of Patients With Advanced Gastric Cancer and Colorectal Cancer

Colorectal Cancer Recurrent

China
Third Military Medical University

Unknown

Apatinib and Chemotherapy Sequential Treatment With Cervical Cancer

Cervical Cancer

China
The University of Hong Kong

Terminated

Effect of Second-look Endoscopy on Peptic Ulcer Rebleeding in Patients With Early Resumption of Antiplatelet Agents

Gastric Ulcer Induced by Anti-platelet Agent | Duodenal Ulcer Induced by Anti-platelet Agent | OGD

China, Hong Kong
Icahn School of Medicine at Mount Sinai

Completed

High Dose Dual Therapy vs Clarithromycin Triple Therapy for Treatment Naive H Pylori Infection in an Urban Population

Helicobacter Pylori Infection

United States
Shanghai Jiao Tong University School of Medicine

Completed

Efficiency Study of Clarithromycin and Bismuth-containing Quadruple Therapy to Treat H.Pylori

Functional Dyspepsia | Peptic Ulcer | Helicobacter Pylori

China
Sun Yat-sen University

Unknown

Study on the Adverse Drug Reactions (ADRs) of Apatinib and Their Biomarker Correlations

Stage IV Cancer

China
Beijing Friendship Hospital

Unknown

A Study of Apatinib Combined With S1 in Patients With Advanced Gastric Cancer

Gastric Cancer

China
Celgene

Not yet recruiting

Study to Evaluate Safety, Drug Levels, Food and Relative Bioavailability of BMS-986365 in Healthy Adult Male Participants

Healthy Participants

United States
Rush University Medical Center

Recruiting

Esomeprazole and Radiation Induced Esophagitis (EERENs)

Locally Advanced Lung Carcinoma | Radiation Esophagitis

United States
Merck KGaA, Darmstadt, Germany

Completed

Effect of a Proton Pump Inhibitor on the PK of Tepotinib

Healthy

Germany
Boehringer Ingelheim

Completed

A Study in Healthy Men to Test How Esomeprazole Influences the Amount of BI 1819479 in the Blood

Healthy

Germany
Zhang Xiaofeng,MD

Active, not recruiting

A RCT of the Efficacy of Tegoprazan 50mg QD in the Treatment of Helicobacter Pylori Infection ( TATH-1 ) (TATH-1)

Helicobacter Pylori Infection | Proton Pump Inhibitor | Vonoprazan

China
Stanford University

Completed

Effect of Proton Pump Inhibitors on Endothelial Function (PPI)

Endothelial Dysfunction

United States
Eli Lilly and Company
Loxo Oncology, Inc.

Completed

A Study of Effect of Food and a Proton Pump Inhibitor on Selpercatinib (LY3527723) in Healthy Participants

Healthy

United States
Peking University First Hospital

Unknown

Phase I Study of Continuous Administration of Salvianolic Acid A Tablet

Diabetes

China
University Hospital Inselspital, Berne
Rigshospitalet, Copenhagen, Denmark (Prof. Moller, Dr. Krag)

Completed

Sup-Icu RENal (SIREN) (SIREN)

Critical Illness | Acute Kidney Injury | Renal Replacement Therapy | End-stage Renal Disease | Proton Pump Inhibitor

Denmark, Switzerland
Seoul National University Hospital

Completed

Lansoprazole in Preterm Infants With Gastroesophageal Reflux (GER)

Gastroesophageal Reflux | Premature Infants

Korea, Republic of
HK inno.N Corporation

Completed

Study to Evaluate the Safety and Efficacy of CJ-12420 in Patients With Erosive Esophagitis

GERD | Erosive Esophagitis

Korea, Republic of
Coordinación de Investigación en Salud, Mexico

Completed

Pantoprazole on Insulin Secretion in Diabetes (IBP)

Type 2 Diabetes

Mexico
Hospital Authority, Hong Kong
The University of Hong Kong

Completed

Prospective Double-blinded Randomized Controlled Trial of 12-weeks High Dose Rabeprazole (Pariet) in the Treatment of Reflux Laryngitis in Chinese Patients

Gastroesophageal Reflux | Laryngitis

China
Janssen Korea, Ltd., Korea

Completed

An Efficacy Study to Compare the Treatment Effects of Rabeprazole and Lansoprazole Depending on the Genotyping of CYP2C19 in Treating Reflux Esophagitis

Reflux Esophagitis
The Catholic University of Korea
Janssen Korea, Ltd., Korea

Completed

Effects of Oral Rabeprazole on the Prevention of Ulcer Bleeding Following Endoscopic Mucosal Resection

Early Gastric Adenocarcinoma | Adenocarcinoma, Tubular

Korea, Republic of
Mayo Clinic

Withdrawn

Predictors of Proton Pump Inhibitor (PPI) Response in Eosinophilic Esophagitis

Gastroesophageal Reflux Disease | Dysphagia | Eosinophilic Esophagitis
AstraZeneca

Completed

Esomeprazole In Patients With Gastric Acid Hypersecretory States Including Idiopathic Hypersecretion and Zollinger-Ellison Syndrome

Zollinger-Ellison Syndrome

United States, France
Dr. Reddy's Laboratories Limited

Completed

Omeprazole Delayed Release (DR) Capsules Bioequivalence Study of Dr. Reddys Under Fasting Conditions

Healthy
Hospital Authority, Hong Kong
The University of Hong Kong

Unknown

The Use of Proton Pump Inhibitor for the Treatment of Non-erosive Gastro-oesophageal Reflux Disease in Chinese Population

Gastroesophageal Reflux

China
AstraZeneca

Completed

Reflux Esophagitis Phase III Study (Maintenance Treatment)

Reflux Esophagitis

Japan
AstraZeneca

Completed

A Multicenter, Randomized, Double-Blind Parallel-Group, Placebo-Controlled Efficacy Study Comparing 4 Weeks of Treatment With Esomeprazole 20 mg Once Daily to Placebo qd for the Resolution of Upper Abdominal Pain in Patients With Symptomatic Gastroesophageal Reflux Disease (sGERD)

Symptomatic Gastroesophageal Reflux Disease (sGERD)
Phillip Song, MD

Withdrawn

Efficacy Study of Botulinum Toxin (BOTOX) Injections to Treat Vocal Fold Granulomas

Granuloma | Contact Ulcer of Vocal Folds | Granuloma of Vocal Cords | Granuloma, Laryngeal

United States
Sun Yat-sen University
Jiangsu HengRui Medicine Co., Ltd.

Unknown

Camrelizumab(SHR-1210) Combined With Apatinib in the Treatment of Advanced Metastatic Colorectal Cancer

Metastatic Colorectal Cancer

China
Cerevel Therapeutics, LLC

Not yet recruiting

A Trial to Evaluate the Effect of Esomeprazole on the Pharmacokinetics of Emraclidine in Healthy Adult Participants

Healthy Participants
Midwest Biomedical Research Foundation
Kansas City Veteran Affairs Medical Center

Completed

Diagnosis of Acid Reflux Disease Using Novel Imaging: A Prospective Study

Non-erosive Reflux Disease

United States, United Kingdom
Bayer

Completed

A Study to Learn How a Proton Pump Inhibitor Affects the Way Elinzanetant (BAY 3427080) Moves Into, Through and Out of the Body, and How Much of it Gets Absorbed by the Body When Taken as a Single and Small Radioactive Dose in Healthy Adults

Hot Flashes | Vasomotor Symptoms as a Sex Hormone-dependent Disorder in Women and Men

Netherlands
Rijnstate Hospital
Erasmus Medical Center

Completed

Rectal and Oral Omeprazole Treatment of Reflux Disease in Infants.

Gastroesophageal Reflux | Hernia, Diaphragmatic | Esophageal Atresia

Netherlands

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