Clinical Trials Sponsored by Alfasigma S.p.A.

Total 669 results

Fidia Farmaceutici s.p.a.

Completed

A Multicentre Clinical Investigation to Assess Efficacy and Safety of Intra-articular Injections of Hyaluronic Acid Combined With Chondroitin Sulfate in Knee Osteoarthritis

Osteo Arthritis Knee

Czechia
Fidia Farmaceutici s.p.a.

Completed

Performance and Safety of Hyalo Gyn Gel on the Treatment of Vaginal Atrophy in Postmenopausal Women

Vulvovaginal Atrophy

Slovakia
Chiesi Farmaceutici S.p.A.

Terminated

A Study to Investigate Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Single and Repeat Doses of CHF6297 in Healthy Subjects and Patients With COPD (CHF6297 FIH)

Chronic Obstructive Pulmonary Disease

United Kingdom
Chiesi Farmaceutici S.p.A.

Completed

Functional Respiratory Imaging Study (FRI) (FRI)

Chronic Obstructive Pulmonary Disease

Belgium, Hungary
AGC Biologics S.p.A.

Completed

Study of NGR-hTNF in Combination With Doxorubicin in Solid Tumors

Cancer

Italy, Netherlands
AGC Biologics S.p.A.

Completed

Study of NGR-hTNF as Single Agent in Patients Affected by Advanced or Metastatic Malignant Pleural Mesothelioma (NGR010)

Malignant Pleural Mesothelioma

Italy
AGC Biologics S.p.A.

Completed

Study of NGR-hTNF Administered at High Doses in Patient With Advanced or Metastatic Solid Tumour

Solid Tumors

Italy
Dompé Farmaceutici S.p.A

Completed

A 2 Weeks Study to Evaluate Tolerability, Safety, Permanence on the Ocular Surface and Efficacy of Two Concentrations of Lubricin Eye Drops Versus Sodium Hyaluronate 0.18% Eye Drops in Patients With Ocular Discomfort Following Refractive Surgery

Ocular Discomfort

Italy
Dompé Farmaceutici S.p.A

Completed

Pilot Study of Reparixin for Early Allograft Dysfunction Prevention in Liver Transplantation

Early Allograft Dysfunction | Ischemia-reperfusion Injury in Liver Transplant

Belarus, Russian Federation
Chiesi Farmaceutici S.p.A.

Completed

A Study Comparing the Efficacy and Safety of CHF 1535 (BDP +FF) Inhalation Powder, Administered Via the NEXT Inhaler, Versus CHF 1535 (BDP +FF), Administered Via a pMDI, in Moderate to Severe Asthma

Asthma

Germany
Chiesi Farmaceutici S.p.A.

Completed

Multicentre, Open Label, Randomized, Two-arm, Parallel-group Study to Assess Efficacy and Safety of ENVARSUS® Compared With Tacrolimus Used as Per Current Clinical Practice in the Initial Maintenance Setting in de Novo Kidney Transplant Patients (STEADY)

End Stage Renal Disease

Italy
Chiesi Farmaceutici S.p.A.

Completed

An Open Label Placebo Study to Assess the Inhalation Profile in Asthmatic Patients Using the Nexthaler® Dry Powder Inhaler (DPI) Device (NEXThalerPIF)

Asthma

Italy
Chiesi Farmaceutici S.p.A.

Completed

Efficacy of CHF1535 Via NEXT DPI Versus pMDI and BDP DPI100µg on PeakExpiratoryFlow in Asthmatic Patients (Neptune)

Asthma

Poland
Chiesi Farmaceutici S.p.A.

Completed

Next DPI LABA, Multicentre, 5-way Cross-over, Adult Asthmatic Patients

Asthma

United Kingdom
Chiesi Farmaceutici S.p.A.

Completed

Efficacy and Tolerability of Beclomethasone Plus Salbutamol in HFA pMDI Fixed Combination vs Beclomethasone Plus Salbutamol in CFC pMDI Fixed Combination in a 12-week Treatment Period of Adult Patients With Uncontrolled Asthma

Bronchial Asthma

Spain, Italy, Russian Federation, Ukraine
Chiesi Farmaceutici S.p.A.

Completed

A Study in Patients With Chronic Obstructive Pulmonary Disease (FUTURE)

Chronic Obstructive Pulmonary Disease

Italy
Chiesi Farmaceutici S.p.A.

Completed

Safety, Tolerability and Efficacy of 28-day Inhaled CHF 6001 DPI in COPD Patients

COPD

United Kingdom, Ireland
Chiesi Farmaceutici S.p.A.

Completed

A Study in Patients With Asthma (NELSON)

Asthma

Italy
AGC Biologics S.p.A.

Completed

Study of NGR-hTNF in Combination With Cisplatin in Solid Tumor

Solid Tumors

Italy
AGC Biologics S.p.A.

Completed

Study of NGR-hTNF as Single Agent in Patients Affected by Advanced or Metastatic Hepatocellular Carcinoma (HCC)

Hepatocellular Carcinoma

Italy
Janssen-Cilag S.p.A.

Completed

Survey on QUality of Life In myeloDisplasia (SQUID)

Myelodysplastic Syndromes
Janssen-Cilag S.p.A.

Completed

A Study to Compare Brachial Artery Reactivity and Cardiovascular Risk of a Treatment Simplification by Darunavir/Ritonavir (DRV/r) 800/100 mg Versus a Triple Combination Therapy Containing DRV/r in HIV-1 Infected Patients (MONARCH)

Human Immunodeficiency Virus 1
Janssen-Cilag S.p.A.

Completed

Paliperidone Extended Release in Schizophrenia Participants With Duration of Illness Less Than 10 Years

Schizophrenia
PH&T S.p.A.

Unknown

Demonstrate the Therapeutic Clinical Equivalence of Two Mometasone Nasal Sprays (PHT-01-12)

Nasal Obstruction | Sneezing | Itching

Argentina
Chiesi Farmaceutici S.p.A.

Completed

Prevalence and Reversibility of Lung Hyperinflation in Asthma (Dist'air2)

Asthma

France
Chiesi Farmaceutici S.p.A.

Completed

Observational Study on the Prophylactic Use of Curosurf in Neonatal Respiratory Distress Syndrome (RDS)

Respiratory Distress Syndrome, Newborn

France
Lenzi Egisto S.P.A.

Completed

Efficacy Study of TEPSO® Socks in Improving Palmoplantar Psoriasis

Palmoplantar Psoriasis

Italy
Chiesi Farmaceutici S.p.A.

Completed

Evaluation of Possible Effects on the QTc Interval of CHF 4226 pMDI in Healthy Volunteers (CT14)

Chronic Obstructive Pulmonary Disease

United States
Montecatone Rehabilitation Institute S.p.A.

Recruiting

Hunova® Randomized Controlled Trial for Trunk Control Improvement in Spinal Cord Injured Patients

Spinal Cord Injury

Italy
Montecatone Rehabilitation Institute S.p.A.

Recruiting

Active tDCS Versus Sham tDCS for Upper Limb Recovery in Incomplete Tetraplegic Patients

Spinal Cord Injury Cervical

Italy
Protalix
Chiesi Farmaceutici S.p.A.

Completed

Study of the Safety and Efficacy of PRX-102 Compared to Agalsidase Beta on Renal Function (BALANCE)

Fabry Disease

United States, Netherlands, Hungary, United Kingdom, Czechia, Norway, Slovenia, Spain, Finland, France, Italy, Switzerland
Protalix
Chiesi Farmaceutici S.p.A.

Completed

Dose-ranging Study of PRX-102 in Adult Fabry Disease Patients

Fabry Disease

United States, Serbia, Spain, United Kingdom, Australia, Paraguay
Philogen S.p.A.
Boehringer Ingelheim

Completed

Trial to Find and Investigate a Safe Dose of F16IL2 and BI 836858 in Patients With AML Relapse After Allogeneic Hematopoietic Stem Cell Transplantation (PHIBI)

Acute Myeloid Leukemia (AML) Relapse

Germany
Chiesi Farmaceutici S.p.A.
Cromsource

Completed

Trial on Safety and Efficacy of Velmanase Alfa Treatment in Pediatric Patients With Alpha-Mannosidosis (rhLaman-08)

Alpha-Mannosidosis

France, Denmark, Austria, Germany, Italy
Kamada, Ltd.
Kedrion S.p.A.

Completed

Post-marketing Study of KamRAB Administered as a Single Dose With Active Rabies Vaccine in Children Exposed to Rabies

Rabies

United States
Nathura S.p.A
Evidilya S.r.l.

Completed

A New Class IIb MD in Proctological Disorders

Proctological Disorders

Italy
Chiesi Farmaceutici S.p.A.
Cromsource

Completed

Envarsus® Once Daily With Everolimus in Elderly Kidney Transplant Recipients: Pharmacokinetic and Clinical Study

Kidney Transplantation

Italy
Montecatone Rehabilitation Institute S.p.A.

Completed

Locomotor Training With Exoskeleton EKSO-GT in Patients With Incomplete Motor Spinal Cord Injury in a Hospital Setting

Spinal Cord Injuries

Italy
sigma-tau i.f.r. S.p.A.

Completed

Propionyl-L-Carnitine in Ulcerative Colitis

Ulcerative Colitis

Italy, Lithuania, Poland, Russian Federation
Philogen S.p.A.
Eudax S.r.l.

Completed

A Dose Finding and Efficacy Study of the Tumour Targeting Human 131I-F16SIP Monoclonal Antibody in Patients With Cancer

Cancer

Italy
sigma-tau i.f.r. S.p.A.

Completed

Efficacy of Rostafuroxin in the Treatment of Essential Hypertension

Essential Hypertension

Belgium
International Biomedical Systems S.p.A.

Unknown

European Multicenter, Randomized, Comparative Efficacy/Safety Study of the Mar-Tyn TiN-Coated Stent (MARTIN)

Coronary Artery Disease | Angioplasty, Transluminal, Percutaneous Coronary | Stents

Germany, Italy, Netherlands, Switzerland
Guerbet
Bracco Imaging S.p.A.

Recruiting

Evaluation of Gadopiclenol for Magnetic Resonance Imaging (MRI) in Japanese Adults and Children

CNS Lesion | Lesion in Body Region

Japan
Nathura S.p.A
Evidilya S.r.l.

Recruiting

Performance and Safety of Class IIb MD Celegyn® in VVA

Vulvovaginal Atrophy

Italy
Dompé Farmaceutici S.p.A
Cromsource

Completed

Study to Evaluate Safety, Tolerability & PK of rhNGF in Healthy Volunteers

Healthy Volunteers

United States
Giuliani S.p.A
FitBiomics, Inc.

Completed

Efficacy of a Mix of Probiotics in Athletes Performance (GIU-PPA-0420)

Healthy

Italy
Protalix
Chiesi Farmaceutici S.p.A.

Completed

Safety, Efficacy, & PK of PRX-102 in Patients With Fabry Disease Administered Intravenously Every 4 Weeks (BRIGHT)

Fabry Disease

United States, Denmark, Belgium, United Kingdom, Norway, Italy, Czechia
Protalix
Chiesi Farmaceutici S.p.A.

Completed

Extension Study of PRX-102 for up to 60 Months

Fabry Disease

United States, Spain, United Kingdom, Paraguay
sigma-tau i.f.r. S.p.A.

Completed

A Pharmacokinetic/Pharmacodynamic Study of Eurartesim Dispersible Formulation in Infants With P.Falciparum Malaria

Malaria,Falciparum

Burkina Faso, Congo, The Democratic Republic of the, Gambia, Mozambique, Tanzania
Philogen S.p.A.
Syneos Health

Completed

A Dose Finding Pharmacokinetic Study of the Tumour-targeting Human L19IL2 Monoclonal Antibody-Cytokine Fusion Protein in Patients With Advanced Solid Tumours

Advanced Solid Tumours

Italy, Germany

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