Clinical Trials Sponsored by Jeanne Hoffman

Total 2971 results

Hoffmann-La Roche

Completed

A Study of Aleglitazar in Monotherapy in Patients With Type 2 Diabetes Mellitus Who Are Drug-Naïve to Anti-Hyperglycemic Therapy

Diabetes Mellitus Type 2

Hong Kong, China, Malaysia
Hoffmann-La Roche

Unknown

An Observational Study on Long-Term Effectiveness and Safety of RoActemra/Actemra (Tocilizumab) in Daily Practice in Patients With Rheumatoid Arthritis (ICHIBAN)

Rheumatoid Arthritis

Germany
Hoffmann-La Roche

Completed

A Study of RO4917838 (Bitopertin) in Patients With Sub-optimally Controlled Symptoms of Schizophrenia (WN25305)

Schizophrenia

United States, China, Italy, Bulgaria, Russian Federation, Japan, Czech Republic
Hoffmann-La Roche

Completed

A Study of RO4905417 in Patients With Non ST-Elevation Myocardial Infarction (Non-STEMI) Undergoing Percutaneous Coronary Intervention

Myocardial Infarction

Poland, United States, Netherlands, Canada
Hoffmann-La Roche

Completed

A Study to Evaluate the Effect of Aleglitazar on Cardiac Energetics and Function in Patients With Type 2 Diabetes Mellitus and no History of Coronary Artery Disease

Diabetes Mellitus Type 2

United Kingdom
Hoffmann-La Roche

Completed

A Study to Measure Serum Periostin, Asthma-Related Biomarkers and Response to Prednisolone in Adult and Adolescent Patients With Severe Oral Corticosteroid-Dependent Asthma

Asthma

United Kingdom
Hoffmann-La Roche

Completed

A Study of R547 in Patients With Advanced Solid Tumors.

Neoplasms

United States
Hoffmann-La Roche

Completed

A Study of Daclizumab (Zenapax) in Combination With Mycophenolate Mofetil (CellCept) and Sirolimus in Prevention of Acute Rejection in Heart Transplant Participants

Heart Transplantation

Spain
Hoffmann-La Roche

Completed

A Study of Dalcetrapib in Patients With Stable Coronary Heart Disease, With Coronary Heart Disease Risk Equivalents or at Elevated Risk for Cardiovascular Disease

Cardiovascular Disease, Coronary Heart Disease, Dyslipidemia, Peripheral Arterial Disease (PAD)

China, United States, Spain, Netherlands, Canada, France, Mexico, Poland, Hungary, Australia, Denmark, United Kingdom, Czech Republic
Hoffmann-La Roche

Withdrawn

PRIMADOS Study:A Study of Avastin (Bevacizumab) Plus Docetaxel for First Line Treatment of Patients With Metastatic Breast Cancer

Breast Cancer
Hoffmann-La Roche

Completed

A Study of Ritonavir-Boosted Danoprevir (RO5190591) in Combination With Pegasys and Ribavirin in Patients With Chronic Hepatitis C Genotype 1

Hepatitis C, Chronic

New Zealand, Poland, France
Hoffmann-La Roche

Completed

An Observational Study of Avastin and Conventional Chemotherapy in Patients >/= 70 Years of Age With Previously Untreated Metastatic Colorectal Cancer (AVAPLUS)

Colorectal Cancer

Belgium
Hoffmann-La Roche

Completed

A Study on The Effect of Multiple Dose Carbamazepine on Single Dose Pharmacokinetics of RO4917838 in Healthy Volunteers

Healthy Volunteer

France
Hoffmann-La Roche

Completed

A Study With Aleglitazar in Patients With a Recent Acute Coronary Syndrome and Type 2 Diabetes Mellitus

Diabetes Mellitus Type 2

Australia, France, Spain, Sweden, China, Korea, Republic of, United States, Canada, Germany, Ireland, Mexico, Poland, India, Denmark, Hungary, United Kingdom, New Zealand, Malaysia, Netherlands, Russian Federation, Thailand, Romania, Ita... and more
Hoffmann-La Roche

Withdrawn

A Study of the Safety of Individualized Combination Therapy With Copegus (Ribavirin) and Pegasys (Peginterferon Alfa-2a) in Patients With Chronic Hepatitis C (MASTER)

Hepatitis C, Chronic
Hoffmann-La Roche

Completed

VICTOR Study - A Study of Valcyte (Valganciclovir po) Compared to Ganciclovir iv in Patients With Cytomegalovirus (CMV) Disease Who Are Solid Organ Transplant Recipients

Cytomegalovirus Infections

Spain, Australia, Ireland, India, Italy, Canada, Belgium, Switzerland, Estonia, Austria, United Kingdom, Brazil, Mexico, Norway, Latvia, Turkey, Croatia, Serbia, Poland, New Zealand, Venezuela
Hoffmann-La Roche

Completed

A Study of the Effect of Carbamazepine on the Pharmacokinetics of RO4917523 in Healthy Volunteers

Healthy Volunteer

France
Hoffmann-La Roche

Completed

A Study of Ibandronate [Bonviva/Boniva] and Alendronate in Female Patients With Post-Menopausal Osteoporosis

Postmenopausal Osteoporosis

Germany
Hoffmann-La Roche

Completed

A Dose- and Efficacy-Finding Study of RO5323441 in Combination With Avastin (Bevacizumab) in Patients With Recurrent Glioblastoma

Glioblastoma Multiforme

Switzerland, France, United Kingdom, Denmark
Hoffmann-La Roche

Completed

A Study of the Elimination, Pharmacokinetics, and Metabolism of RO5424802

Healthy Volunteer

Netherlands
Hoffmann-La Roche

Completed

A Study of Administration of Trastuzumab (Herceptin) by a Single-use Injection Device Versus a Handheld Syringe

Healthy Volunteer

New Zealand
Hoffmann-La Roche

Completed

A Study of Danoprevir in Combination With Low-Dose Ritonavir in Healthy Subjects

Healthy Volunteer

France
Hoffmann-La Roche

Completed

A Study to Assess Use of Zenapax (Daclizumab) and CellCept (Mycophenolate Mofetil) to Improve Kidney Function in Kidney Transplant Patients

Kidney Transplantation

Belgium, Spain, Sweden, Germany, United States, France, Canada, United Kingdom, Australia, Poland, Norway, Mexico
Hoffmann-La Roche

Completed

A Pharmacokinetic Study of RO4917523 in Healthy Japanese and Caucasian Subjects

Healthy Volunteer

United States
Hoffmann-La Roche

Completed

A Retrospective Biomarker Study of Stored Samples Obtained From Patients With Chronic Hepatitis B

Hepatitis B, Chronic

Hong Kong, Taiwan, Singapore, Korea, Republic of, New Zealand, France, Thailand, Russian Federation, Australia, Italy
Hoffmann-La Roche

Completed

A Retrospective Observational Study on Compliance in Patients With Rheumatoid Arthritis on Treatment With RoActemra/Actemra (Tocilizumab) in Clinical Practice (REMISSION II)

Rheumatoid Arthritis

Greece
Hoffmann-La Roche

Completed

A Study of RO4917838 (Bitopertin) in Patients With Acute Exacerbation of Schizophrenia

Schizophrenia

United States, Slovakia, Romania, Russian Federation, Ukraine
Hoffmann-La Roche

Completed

A Study of PEGASYS (Peginterferon Alfa-2a [40KD]) in Patients With Hepatitis B e Antigen (HBeAg)-Negative Chronic Hepatitis B Virus (HBV)

Hepatitis B, Chronic

Bulgaria
Hoffmann-La Roche

Completed

A Study on Safety, Tolerability and Pharmacokinetics of RO5303253 in Healthy Volunteers and Patients With Chronic Hepatitis C Genotype 1

Hepatitis C, Chronic, Healthy Volunteer

New Zealand
Hoffmann-La Roche

Completed

A Study of Xeloda (Capecitabine) in Patients With Advanced and/or Metastatic Colorectal Cancer

Colorectal Cancer

United States
Hoffmann-La Roche

Completed

A Study of the Effect of Multiple Doses of Itraconazole and Fluoxetine on the Pharmacokinetics of a Single Dose of RO5285119 in Healthy Subjects

Healthy Volunteer

Netherlands
Hoffmann-La Roche

Completed

A Study of RO4917838 (Bitopertin) in Patients With Persistent, Predominant Negative Symptoms of Schizophrenia (WN25309)

Schizophrenia

Germany, Spain, Turkey, Canada, United States, Netherlands, Chile, Brazil, Taiwan, Poland, Ukraine, Slovakia, Lithuania, Latvia
Hoffmann-La Roche

Completed

A Study to Assess the Safety and Efficacy of Tocilizumab in Patients With Active Rheumatoid Arthritis

Rheumatoid Arthritis

France, Italy, Spain, United States, Australia, Canada, Mexico, South Africa, Portugal, Slovenia, Serbia, Israel, Lithuania, Argentina, China, Denmark, Norway, Peru
Hoffmann-La Roche

Completed

QUALITE Study - A Study of Fuzeon (Enfuvirtide) in Treatment-Experienced Patients With Human Immunodeficiency Virus-1 (HIV-1) Infection

HIV Infections

United States, Puerto Rico
Hoffmann-La Roche

Completed

An Observational Study of RoActemra/Actemra (Tocilizumab) in Patients With Rheumatoid Arthritis Who Have an Inadequate Response to DMARDs

Rheumatoid Arthritis

Slovakia
Hoffmann-La Roche

Completed

A Study of Single Dose Inclacumab in Japanese Healthy Volunteers Compared to Caucasian Healthy Volunteers

Healthy Volunteer

United States
Hoffmann-La Roche

Completed

A Study of RO5093151 in Patients With Ocular Hypertension Or Open Angle Glaucoma

Hypertension, Glaucoma, Open-Angle

United States, Bulgaria, Czech Republic, Hungary
Hoffmann-La Roche

Completed

Observational Study on Predictors of Response to Invirase (Saquinavir) Treatment in Treatment-naïve Patients With HIV Infection

HIV Infections

Poland
Hoffmann-La Roche

Completed

A Multiple Ascending Dose Study of R1450 in Patients With Alzheimer Disease.

Alzheimer's Disease

Sweden, Israel, Denmark, Netherlands, United Kingdom
Hoffmann-La Roche

Completed

A Study on the Effect of Renal Impairment on the Pharmacokinetics of RO4917838

Healthy Volunteer

France, Russian Federation
Hoffmann-La Roche

Completed

A Study of RO5428029 in Healthy Volunteers and Patients With Chronic Hepatitis C

Hepatitis C, Chronic, Healthy Volunteer

Poland, France, Netherlands
Hoffmann-La Roche

Withdrawn

A Study of The Safety Profile of First-line Avastin (Bevacizumab) in Combination With Paclitaxel in Patients With Locally Recurrent or Metastatic Her2-negative Breast Cancer (AVATAX)

Breast Cancer
Hoffmann-La Roche

Completed

An Observational Study on The Prediction of Adverse Events in Patients With Chronic Hepatitis C Receiving a Long-Acting Interferon Plus Ribavirin (GUARD-C)

Hepatitis C, Chronic

Belgium, Greece, Slovakia, Hungary, Italy, Korea, Republic of, Poland, Romania, Bosnia and Herzegovina, Serbia, Brazil, Morocco, Portugal, India, Egypt, Pakistan, Lebanon, Kuwait, Macedonia, The Former Yugoslav Republic of, Qatar and more
Hoffmann-La Roche

Completed

A Pharmacodynamic and Pharmacokinetic Study of RO5508887 in Healthy Volunteers

Healthy Volunteer

United States
Hoffmann-La Roche

Completed

A Study of Mircera for the Treatment of Anemia in Dialysis Patients

Anemia

Spain, United States, Czech Republic, Canada, Greece, Switzerland, Thailand, Poland, Russian Federation, Sweden, South Africa, Norway, Brazil
Hoffmann-La Roche

Completed

A Study of DPP-IV Inhibitor in Patients With Type 2 Diabetes

Diabetes Mellitus Type 2

Mexico, United States, Estonia, Bulgaria, Latvia, Romania, Lithuania, Puerto Rico, Costa Rica
Hoffmann-La Roche

Completed

A Study of RG7625 in Healthy Volunteers

Healthy Volunteer

Netherlands
Hoffmann-La Roche

Completed

A Single Ascending And Multiple Ascending Dose Study of RO5271983 in Healthy Volunteers

Healthy Volunteer

New Zealand
Hoffmann-La Roche

Completed

A Study of RO4917838 (Bitopertin) in Patients With Sub-optimally Controlled Symptoms of Schizophrenia (WN25306)

Schizophrenia

Germany, Spain, Turkey, Canada, United States, Netherlands, Chile, Brazil, Taiwan, Poland, Ukraine, Slovakia, Lithuania, Latvia
Hoffmann-La Roche

Completed

A Safety, Pharmacokinetics and Pharmacodynamics Study of RO6811135 in Patients With Type 2 Diabetes Mellitus

Diabetes Mellitus Type 2

United States

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