Clinical Trials Sponsored by Léa Gouaux

Total 7754 results

Hoffmann-La Roche

Completed

A Long-Term Safety Extension Study of WA19926 in Participants With Rheumatoid Arthritis

Rheumatoid Arthritis

Hungary
Hoffmann-La Roche

Terminated

A Study of Subcutaneous Mircera, Versus no Erythropoiesis-Stimulating Agent (ESA) Therapy, in the Treatment of Anemia in Patients With Chronic Kidney Disease After Kidney Transplant

Anemia

France, United Kingdom, Germany, Spain, Belgium, Italy
Hoffmann-La Roche

Completed

A Non-Interventional Study of RoActemra/Actemra (Tocilizumab) Treatment in Patients With Rheumatoid Arthritis

Rheumatoid Arthritis

Panama, Costa Rica, Dominican Republic, Guatemala
Hoffmann-La Roche

Completed

A Study of RO5095932 in Patients With Type 2 Diabetes Mellitus

Diabetes Mellitus Type 2

United States
Hoffmann-La Roche

Completed

A Study of The Effects of Multiple Doses of Ketoconazole on Single Dose Pharmacokinetics of RO4602522 in Healthy Male Volunteers

Healthy Volunteer

Netherlands
Hoffmann-La Roche

Completed

A Study of the Effect of Fluvoxamine on the Pharmacokinetics of RO4917523 in Healthy Volunteers

Healthy Volunteer

France
Hoffmann-La Roche

Completed

An Observational Study on the Safety Profile of MabThera/Rituxan (Rituximab) in Combination With Chemotherapy in Patients With B Cell-lineage Chronic Lymphocytic Leukaemia (MABERYC)

Lymphocytic Leukemia, Chronic

Spain
Hoffmann-La Roche

Completed

A Single Center Study to Evaluate the Penetration of RO7033877 Into the Lung in Healthy Volunteers

Healthy Volunteer

United States
Hoffmann-La Roche

Completed

An Observational Study of Tarceva (Erlotinib) in Previously Treated Patients With Advanced Non-Small Cell Lung Cancer With Wild-Type Epidermal Growth Factor Receptor (EGFR) Gene (WILT)

Non-Squamous Non-Small Cell Lung Cancer

Spain
Hoffmann-La Roche

Completed

A Study of Combination Treatment With Pegasys (Peginterferon Alfa) and Copegus (Ribavirin)in Patients With Chronic Hepatitis C

Hepatitis C, Chronic

Israel
Hoffmann-La Roche

Completed

A Study of Hepatitis C Virus (HCV) Polymerase Inhibitor Pro-Drug in Combination With PEGASYS With or Without COPEGUS in Patients With Chronic Hepatitis C (CHC) Genotype 1 Infection.

Hepatitis C, Chronic

United States, Puerto Rico
Hoffmann-La Roche

Completed

Safety of Herceptin/Trastuzumab in Metastatic Breast Cancer

Breast Cancer, Metastatic Breast Cancer

Serbia
Hoffmann-La Roche

Completed

A Study on The Potential of Aleglitazar to Reduce Cardiovascular Risk in Patients With Stable Cardiovascular Disease and Glucose Abnormalities

Cardiovascular Disease, Diabetes Mellitus Type 2

Germany, Spain, Korea, Republic of, United States, Colombia, Mexico, Hungary, Canada, Austria, Estonia, Malaysia, Australia, Poland, Thailand, Czech Republic, Latvia, Italy, Romania, Russian Federation, Chile, Lithuania, Sweden, United... and more
Hoffmann-La Roche

Completed

A Long-Term Extension Study of RoActemra/Actemra (Tocilizumab) in Patients With Juvenile Idiopathic Arthritis Who Completed WA19977 Core Study

Juvenile Idiopathic Arthritis

Germany
Hoffmann-La Roche

Completed

A Study of P38 Inhibitor (4) in Patients With Active Rheumatoid Arthritis (RA) on Stable Methotrexate Therapy

Rheumatoid Arthritis

Germany, Poland, United States, Australia, Brazil, Canada, Estonia, Greece, Ireland, Mexico, New Zealand, South Africa, Spain, United Kingdom
Hoffmann-La Roche

Completed

A Study of the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of RO5545965 in Healthy Volunteers

Healthy Volunteer

Netherlands
Hoffmann-La Roche

Completed

A Study of Xeloda (Capecitabine) in Breast Cancer Patients With Central Nervous System (CNS) Progression

Breast Cancer

France
Hoffmann-La Roche

Completed

A Study of Xeloda (Capecitabine) in Patients With Advanced and/or Metastatic Colorectal Cancer

Colorectal Cancer

United States
Hoffmann-La Roche

Completed

An Observational Study of Tarceva (Erlotinib) in First Line in Patients With Advanced EGFR Mutation-Positive Non-Small Cell Lung Cancer (GERTAC)

Non-Squamous Non-Small Cell Lung Cancer

Germany
Hoffmann-La Roche

Terminated

A Non-Interventional Study of RoActemra/Actemra (Tocilizumab) in Monotherapy in Patients With Rheumatoid Arthritis (MONACO)

Rheumatoid Arthritis

Portugal
Hoffmann-La Roche

Completed

A Study of RO5285119 in Healthy Volunteers

Healthy Volunteer

France
Hoffmann-La Roche

Completed

A Study Comparing Mircera and Epoetin Beta for the Treatment of Anemia in Dialysis Patients With Chronic Kidney Disease.

Anemia

China, Hong Kong
Hoffmann-La Roche

Completed

A Study of the Effect of Taspoglutide on Gastric Emptying in Patients With Type 2 Diabetes

Diabetes Mellitus Type 2

Germany, United Kingdom
Hoffmann-La Roche

Completed

TESRA: (Treatment of Emphysema With a Gamma-Selective Retinoid Agonist)

Emphysema

United States, South Africa, Hungary, Poland, Bulgaria, Latvia, Israel, Italy, Czech Republic, United Kingdom, Ukraine, Iceland
Hoffmann-La Roche

Completed

A Study on the Effect of Renal Function on the Pharmacakokinetics of RO5024048 (Parent of Prodrug RO5024048) Following Multiple Oral Dose Administration of RO5024048

Healthy Volunteer

New Zealand, United States
Hoffmann-La Roche

Completed

A Study on the Effects of Valproate on the Pharmacokinetics of RO4917838 in Healthy Volunteers

Healthy Volunteer

France
Hoffmann-La Roche

Completed

A Study of Hepatitis C Virus (HCV) Polymerase Inhibitor Pro-Drug in Combination With PEGASYS Plus COPEGUS Compared With PEGASYS Plus COPEGUS in Patients With Chronic Hepatitis C Genotype 1 Infection.

Hepatitis C, Chronic

Australia, France, Italy, Spain, Germany, United States, Canada, Austria, Puerto Rico
Hoffmann-La Roche

Completed

A Study of Ibandronate (Bondronat) in Participants With Malignant Bone Disease

Pain; Bone Neoplasms; Neoplasm Metastasis

Bulgaria
Hoffmann-La Roche

Completed

A Study of Aleglitazar in Combination With Metformin in Patients With Type 2 Diabetes Mellitus Who Are Inadequately Controlled With Metformin Monotherapy

Diabetes Mellitus Type 2

Korea, Republic of, China
Hoffmann-La Roche

Completed

A Pharmacokinetic Study of RO4917838 in Healthy Chinese Volunteers

Healthy Volunteer

China
Hoffmann-La Roche

Completed

A Study of Aleglitazar in Combination With Oral Contraceptive Healthy Volunteers

Healthy Volunteer

United Kingdom
Hoffmann-La Roche

Completed

A Retrospective Chart Review on the Use of Biologics in Monotherapy for the Treatment of Patients With Rheumatoid Arthritis

Rheumatoid Arthritis

United Kingdom
Hoffmann-La Roche

Terminated

An Observational Study of Pegasys (Peginterferon Alfa-2a) in Patients With Chronic Hepatitis B Who Have Failed Antiviral Treatment With Nucleoside (Nucleotide) Analogues

Hepatitis B, Chronic

Poland
Hoffmann-La Roche

Completed

A Study of Ibandronate (Bonviva) in Patients With Post-Menopausal Osteoporosis

Postmenopausal Osteoporosis

United States
Hoffmann-La Roche

Completed

A Phase 1 Clinical Study in Healthy Volunteers to Investigate the Drug-drug Interaction Between Multiple Doses of RO7033877 and Multiple Doses of Colistin Methanesulfonate Sodium (CMS)

Healthy Volunteer

Netherlands
Hoffmann-La Roche

Completed

A Study of RO5429083 Alone or in Combination With Cytarabine in Patients With Acute Myelogenous Leukemia

Myelogenous Leukemia, Acute

France, Germany, Italy
Hoffmann-La Roche

Completed

A Study to Evaluate the Bioequivalence of Tocilizumab Following Subcutaneous Administration Via an Autoinjector (AI 1000-G2) Versus a Pre-Filled Syringe in Healthy Volunteers

Healthy Volunteer

United States
Hoffmann-La Roche

Completed

A Single Dose Study of Radiolabeled RO4602522 in Healthy Volunteers

Healthy Volunteer

Netherlands
Hoffmann-La Roche

Completed

A Study Evaluating the Efficacy and Safety of Lebrikizumab in Adult Patients With Mild to Moderate Asthma

Asthma

United States, South Africa, Russian Federation, Puerto Rico, New Zealand, Poland, Bulgaria, Romania, Brazil, Canada, United Kingdom, Czech Republic, Georgia, Slovakia
Hoffmann-La Roche

Completed

A Study of Capecitabine (Xeloda) in Participants With Advanced or Metastatic Gastric Cancer

Gastric Cancer

Hong Kong, Colombia, Russian Federation, Peru, Korea, Republic of, China, Mexico, Brazil, Argentina, Guatemala, Uruguay, Malaysia, Belize, Panama
Hoffmann-La Roche

Completed

A Study of Capecitabine (Xeloda) and Peginterferon Alfa-2a (Pegasys) in Treatment-Naive Participants With Advanced Liver Cancer

Carcinoma, Hepatocellular

China, Thailand, Taiwan
Hoffmann-La Roche

Completed

PRIOR Study - A Study of Ibandronate (Boniva) in Postmenopausal Women With Osteoporosis or Osteopenia

Postmenopausal Osteoporosis

United States
Hoffmann-La Roche

Completed

An Observational Study of Glucocorticoid Use in Patients With Rheumatoid Arthritis on Treatment With RoActemra/Actemra (Tocilizumab)

Rheumatoid Arthritis

France
Hoffmann-La Roche

Completed

A Single-center Study to Investigate How Quickly and to What Extent a Radioactive Dose of RO5285119 is Absorbed, Metabolized and Eliminated From the Body of Healthy Male Volunteers

Healthy Volunteer

Netherlands
Hoffmann-La Roche

Terminated

A Multiple Ascending Dose Study of the mTOR Inhibitor (RAD001) in Combination With R1507 in Patients With Advanced Solid Tumors

Neoplasms

Italy, United States
Hoffmann-La Roche

Completed

A Study of RO4989991 in Patients With Allergic Rhinitis

Asthma

United States
Hoffmann-La Roche

Completed

An Observational Study of Pegasys (Peginterferon Alfa-2a) in Patients With HBeAg-Positive or HBeAg-Negative Chronic Hepatitis B

Hepatitis B, Chronic

Germany
Hoffmann-La Roche

Completed

A Study of RO5024048 in Combination With Ritonavir-Boosted Danoprevir With or Without Copegus (Ribavirin) in Interferon-Naïve Patients With Chronic Hepatitis C Genotype 1 (INFORM-SVR)

Hepatitis C, Chronic

France, Germany, United States, New Zealand
Hoffmann-La Roche

Completed

A Dose-Finding and Exploratory Study of RO5323441 in Combination With Sorafenib in Patients With Hepatocellular Carcinoma

Carcinoma, Hepatocellular

Singapore
Hoffmann-La Roche

Completed

A Study of Danoprevir/Ritonavir and Copegus With RO5024048 and/or Pegasys in Patients With Chronic Hepatitis C

Hepatitis C, Chronic

United States, Spain, France, Canada, Germany, Austria, Australia, Brazil, United Kingdom, Italy, Mexico, Poland, Puerto Rico

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