Clinical Trials Sponsored by Lung Clinic Hemer

Total 719 results

National Heart, Lung, and Blood Institute (NHLBI)

Completed

MRI to Detect Embolism Following Angiography and Angioplasty-Stenting of the Renal Artery

Renal Artery Obstruction | Kidney Disease

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Effects of Salt Intake on the Nervous Systems of Patients With Salt-Sensitive High Blood Pressure

Hypertension | Hyperaldosteronism

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Investigation Into the Use of Ultrasound Technique in the Evaluation of Heart Disease

Healthy | Hypertrophic Cardiomyopathy | Left Ventricular Hypertrophy

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Higher-Dose Ezetimibe to Treat Homozygous Sitosterolemia

Heart Diseases | Metabolism, Inborn Errors

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Safety and Dosing Evaluation of REG1 Anticoagulation System

Healthy

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Analysis of Heart Muscle Function Following Exercise in Patients With Heart Disease

Healthy

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Magnetic Resonance Imaging of Narrowed Arteries

Arteriosclerosis

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

The Effect of Exercise on Stem Cell Mobilization and Heart Function in Patients Undergoing Cardiac Rehabilitation

Coronary Arteriosclerosis

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

The Role of Heart Stiff and Weak Atrium on Exercise Capacity in Patients With Hypertrophic Cardiomyopathy

Cardiomyopathy, Hypertrophic

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

MRI Evaluation of Chest Pain

Myocardial Infarction | Coronary Disease | Chest Pain

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Collection of Liver Tissue for Virologic Studies

Virus Disease

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Eculizumab to Treat Paroxysmal Nocturnal Hemoglobinuria

Hemoglobinuria, Paroxysmal

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Effect of Insulin on Endothelin-Dependent Vascular Tone in the Forearm Circulation

Hyperinsulinemia

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Signs and Symptoms Associated With Molecular Defects in Genetically Inherited Heart Disease

Congenital Heart Defect

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Determination of Variances in Exhaled Nitric Oxide Output in Normal Healthy Male Volunteers Consuming High and Low Nitrate/Nitrite Diets

Healthy

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

An Epidemiological Study of Subjects With Immune Thrombocytopenic Purpura to Evaluate the Relationship Between Platelet Counts, Endogenous Thrombopoietin Levels, Endogenous Anti-Thrombopoietin Antibodies, and Selected Autoimmune Markers

Purpura, Thrombocytopenic, Idiopathic | Immune Thrombocytopenic Purpura

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Treatment of T-Large Granular Lymphocyte (T-LGL) Lymphoproliferative Disorders With Cyclosporine

Anemia | Thrombocytopenia | Neutropenia | Leukemia, T-Cell | Lymphocytosis

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

A Comparison of Two Treatments: Pacemaker and Percutaneous Transluminal Septal Ablation for Hypertrophic Cardiomyopathy

Hypertrophic Cardiomyopathy

United States
National Heart, Lung, and Blood Institute (NHLBI)
National Institutes of Health Clinical Center (CC)

Recruiting

Early Detection of Infectious and Noninfectious Lung Diseases Following Allogeneic Hematopoietic Stem Cell Transplantation

Allogeneic Hematopoietic Stem Cell Transplantation (HSCT)

United States
National Heart, Lung, and Blood Institute (NHLBI)

Not yet recruiting

Study to Evaluate the Safety and Tolerability of Escalating Doses of Fostamatinib in Subjects With Stable Sickle Cell Disease

Sickle Cell Disease | Sickle Cell Disorders | Hb-SS Disease | Hemoglobin S | Disease Sickle Cell Anemia | Hemoglobin Beta Thalassemia Disease

United States
National Heart, Lung, and Blood Institute (NHLBI)

Recruiting

Observational Study of Cardiac Arrhythmias During Treatment With BTK Inhibitors or Venetoclax

Mantle Cell Lymphoma | Chronic Lymphocytic Leukemia (CLL) | Sudden Cardiac Death | Hematologic Malignancies | Cardiac Arrhythmias | Waldenstr(SqrRoot)(Delta)m s Macroglobulinemia

United States
National Heart, Lung, and Blood Institute (NHLBI)

Recruiting

Using Fostamatinib to Treat Post-Hematopoietic Stem Cell Transplant Immune-mediated Cytopenias

Immune Mediated Anemia | Immune Mediated Thrombocytopenia | Chronic GVHD

United States
National Heart, Lung, and Blood Institute (NHLBI)

Recruiting

Controls and Healthy Vasculature Initiative

Healthy Volunteers | Vascular And Immunologic Diseases

United States
National Heart, Lung, and Blood Institute (NHLBI)

Recruiting

Characterization of Tissue-Specific Immune Responses to Bronchoscopic Instillation of Mycobacterial Antigens Into the Human Lung

Healthy | Latent Tuberculosis Infection (LTBI)

United States
National Heart, Lung, and Blood Institute (NHLBI)

Recruiting

Gene First Approach to Connective Tissue Disease

Vascular Diseases | Connective Tissue Diseases | Abnormal Elastogenesis

United States
National Heart, Lung, and Blood Institute (NHLBI)

Recruiting

Geospatial Analysis of Neighborhood Environmental Stress in Relation to Biological Markers of Cardiovascular Health and Health Behaviors in Women

Cardiovascular (CV) Risk

United States
National Heart, Lung, and Blood Institute (NHLBI)

Recruiting

Genotype -Phenotype Correlation of PKLR Variants With Pyruvate Kinase, 2,3-Diphosphglycerate and Adenosine Triphosphate Activities in Red Blood Cells of People With Sickle Cell Disease

Sickle Cell | PKLR Variants | Adenosine Triphosphate Activities

United States
National Heart, Lung, and Blood Institute (NHLBI)

Recruiting

Low-Dose Danazol for the Treatment of Telomere Related Diseases

Telomere Disease

United States
National Heart, Lung, and Blood Institute (NHLBI)

Recruiting

Discovery of Sirolimus Sensitive Biomarkers in Blood

Lymphangioleiomyomatosis

United States
National Heart, Lung, and Blood Institute (NHLBI)

Recruiting

Unrelated Umbilical Cord Blood Transplantation for Severe Aplastic Anemia and Hypo-plastic MDS Using CordIn(TM), Umbilical Cord Blood-Derived Ex Vivo Expanded Stem and Progenitor Cells to Expedite Engraftment and Improve Transplant Outcome

Myelodysplastic Syndrome (MDS) | Severe Aplastic Anemia | Hypo-Plastic MDS

United States
National Heart, Lung, and Blood Institute (NHLBI)

Recruiting

Impact of Elastin Mediated Vascular Stiffness on End Organs

Cardiovascular Disease | Williams Syndrome | Supravalvular Aortic Stenosis

United States
National Heart, Lung, and Blood Institute (NHLBI)

Recruiting

Williams Syndrome (WS) and Supravalvar Aortic Stenosis (SVAS) DNA and Tissue Bank

Cardiovascular Disease | Williams Syndrome | Supravalvular Aortic Stenosis

United States
National Heart, Lung, and Blood Institute (NHLBI)

Recruiting

Nebulized or Inhaled Albuterol for Lymphangioleiomyomatosis

Lymphangioleiomyomatosis

United States
National Heart, Lung, and Blood Institute (NHLBI)

Recruiting

Characterization of Patients With Uncommon Presentations and/or Uncommon Diseases Associated With the Cardiovascular System

Parkinson's Disease | Atherosclerosis | Cardiomyopathy | Li-Fraumeni Syndrome | Cardiovascular Capacity

United States
National Heart, Lung, and Blood Institute (NHLBI)

Recruiting

Natural History Study of Monoclonal B Cell Lymphocytosis (MBL), Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CLL/SLL), Lymphoplasmacytic Lymphoma (LPL)/Waldenstrom Macroglobulinemia (WM), and Splenic Marginal Zone Lymphoma (SMZL)

Waldenstrom Macroglobulinemia | Lymphoplasmacytic Lymphoma | Small Lymphocytic Lymphoma | CLL (Chronic Lymphocytic Leukemia) | Monoclonal B-Cell Lymphocytosis

United States
National Heart, Lung, and Blood Institute (NHLBI)

Recruiting

Collection of Lung Fluid and Tissue Samples for Research

Respiratory Tract Diseases | Leukocyte Disorders | Bronchoscopy

United States
National Heart, Lung, and Blood Institute (NHLBI)

Recruiting

Causes and Natural History of Dyslipidemias

Atherosclerosis | Hypercholesterolemia

United States
National Heart, Lung, and Blood Institute (NHLBI)

Recruiting

Collection of Tissue Specimens From Patients With Solid Tumors or Blood Disorders and Their HLA-Compatible Family Members

Neoplasms | Hematologic Neoplasms | Healthy Volunteers

United States
National Heart, Lung, and Blood Institute (NHLBI)

Recruiting

Genetic Basis of Immunodeficiency

Severe Combined Immunodeficiency

United States
National Heart, Lung, and Blood Institute (NHLBI)

Recruiting

Blood Collection for Research Related to Certain Diseases Involving Blood Vessels

Sickle Cell Disease

United States
National Heart, Lung, and Blood Institute (NHLBI)

Recruiting

Study of the Disease Process of Lymphangioleiomyomatosis

Pneumothorax | Tuberous Sclerosis | Lung Disease | Lymphangioleiomyomatosis

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

CADASIL Disease Discovery

Cardiovascular Disease | Arterial Stiffness | Germline Mutation in the NOTCH 3 Gene | Pathogenesis of CADASIL | Clinical Phenotype of CADASIL

United States
National Heart, Lung, and Blood Institute (NHLBI)

Enrolling by invitation

Data Collection of Standard Care and Evaluation of NHLBI Patients and Donors

Hematologic Diseases | Wide Spectrum of Diseases

United States
National Heart, Lung, and Blood Institute (NHLBI)

Enrolling by invitation

Investigating the Mechanistic Effects of Mitapivat in Subjects With Sickle Cell Disease

Sickle Cell Anemia | Sickle Beta Thalassemia | Sickle Cell Thalassemia | Sickle Beta Zero Thalassemia | Sickle Cell Pain | Hbss | Hbsc | Sickle Cell Syndrome Variant

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Lipoprotein Metabolism in Normal Volunteers and Patients With High Levels of Lipoproteins

Dyslipidemia | Hypercholesterolemia | Hyperlipidemia | Hypolipoproteinemia

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Pathophysiology of Acute Pain in Patients With Sickle Cell Disease

Sickle Cell Disease

United States
National Heart, Lung, and Blood Institute (NHLBI)

Active, not recruiting

Venous Thrombosis Biomarkers in Sickle Cell Disease and Sickle Cell Trait

Venous Thrombosis | Sickle Cell Disease | Venous Thromboembolism | Sickle Cell Trait | Hypercoagulable State

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Intravenous ACP-501 for Familial LCAT Deficiency (rhLCAT)

Familial LCAT Deficiency

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Cellular and Molecular Characterization of the Immune Response in Healthy NIH Employees atBaseline, and After Immunization With the H1N1 or Seasonal Influenza Vaccines

Influenza | Healthy Volunteers

United States
National Heart, Lung, and Blood Institute (NHLBI)

Active, not recruiting

Evaluation of Lipoproteins

Evaluation of Plasma Lipoproteins

United States

Clinical Trials Sponsored by Lung Clinic Hemer

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