Clinical Trials Sponsored by MGH Institute of Health Professions

Total 19154 results

National Institute of Mental Health (NIMH)

Completed

An Investigation of the Antidepressant Efficacy of the 5-HT2A Antagonist, M100907, in Combination With Citalopram in Treatment Resistant Depression

Depressive Disorder

United States
National Institute of Mental Health (NIMH)

Completed

Effects of Hydrocortisone in Patients With Post-Traumatic Stress Disorder

Healthy | Post-Traumatic Stress Disorders

United States
National Institute of Mental Health (NIMH)

Completed

Role of Substance P in Post-Traumatic Stress Disorder

Post-Traumatic Stress Disorder

United States
National Institute of Mental Health (NIMH)

Completed

Use of [18F]FECNT in Positron Emission Tomography

Healthy

United States
National Institute of Mental Health (NIMH)

Completed

Cortical Excitability in Obsessive-Compulsive and Related Disorders

Healthy | Obsessive Compulsive Disorder

United States
National Institute of Mental Health (NIMH)

Completed

I-123 Brain Studies of Serotonin Metabolism in Psychiatric Patients and Normal Volunteers

Healthy | Schizophrenia | Obsessive Compulsive Disorder | Tourette Syndrome | Mental Disorder

United States
National Institute of Mental Health (NIMH)

Completed

L-5-HTP-Related EMS

Eosinophilia-Myalgia Syndrome

United States
National Institute of Mental Health (NIMH)

Completed

Neuroimaging of Dopamine Metabolism in Normal and Psychiatric Patients

Healthy | Schizophrenia

United States
National Institute of Mental Health (NIMH)

Completed

Study of the Hypothalmic-Pituitary-Adrenal (HPA) Axis and Its Role in Major Depression

Mood Disorders | Healthy | Fatigue Syndrome, Chronic

United States
National Institute of Mental Health (NIMH)

Completed

Clonazepam and Paroxetine for Rapid Treatment of Post-Traumatic Stress Disorder

Post Traumatic Stress Disorder

United States
National Institute of Mental Health (NIMH)

Completed

Effects of Stress Hormones on Emotion and Cognition

Healthy

United States
National Institute of Mental Health (NIMH)

Completed

Preventive Measures for Childhood-Onset Obsessive-Compulsive Disorder and Tic Disorders (PANDAS Subgroup)

Obsessive Compulsive Disorder | Tic Disorder | Streptococcal Infection | Mental Disorder Diagnosed in Childhood

United States
National Institute of Mental Health (NIMH)

Completed

Serotonin Transporters in Alcoholism

Alcoholism

United States
National Institute of Mental Health (NIMH)

Completed

Imaging of Brain Receptors in Healthy Volunteers and in Patients With Schizophrenia

Schizophrenia

United States
National Institute of Mental Health (NIMH)

Completed

Effects of Sex Hormones on Circadian Rhythm in Men and Women

Depressive Disorder | Bipolar Disorder | Circadian Rhythm

United States
National Institute of Mental Health (NIMH)

Completed

Propranolol for the Treatment of Acute Stress Disorder

Stress Disorders, Traumatic, Acute

United States
National Institute of Mental Health (NIMH)

Completed

Clozapine for Treatment-Resistant Mania

Bipolar Disorder

United States
National Institute of Mental Health (NIMH)

Completed

The Effect of GnRH on Pitutitary Hormones in Menstrual-Cycle Mood Related Disorders

Mental Disorders | Depressive Disorder | Mood Disorders | Healthy

United States
National Institute of Mental Health (NIMH)

Completed

Neuropsychiatric Effects of Interferon-Alpha and Ribavirin

Mental Disorder

United States
National Institute of Mental Health (NIMH)

Completed

Brain Structure and Function Before and After Treatment for Post-Traumatic Stress Disorder

Stress Disorders, Post-Traumatic

United States
National Institute of Mental Health (NIMH)

Completed

Effect of Transcranial Magnetic Stimulation on Memory

Healthy | Healthy Volunteer | HV

United States
National Institute of Mental Health (NIMH)

Completed

Study of the Psychological Development of Children of Parents With and Without Affective Disorders

Bipolar Disorder | Mood Disorder | Involutional Depression

United States
National Institute of Mental Health (NIMH)

Completed

Neuroimaging of St. John's Wort-Induced Changes of Serotonin Metabolism in Normal Subjects

Healthy | Mood Disorder

United States
Ottawa Heart Institute Research Corporation
Canadian Institutes of Health Research (CIHR); Medtronic

Completed

Resynchronization/Defibrillation for Ambulatory Heart Failure Trial (RAFT)

Heart Failure, Congestive

Canada, Netherlands, Australia, Turkey, Denmark, Germany, Belgium
Montreal Heart Institute
Canadian Institutes of Health Research (CIHR); Abbott Medical Devices

Completed

Evaluation of Resynchronization Therapy for Heart Failure (EARTH) (EARTH)

Heart Failure

Canada
Montreal Heart Institute
Canadian Institutes of Health Research (CIHR); Abbott Medical Devices

Terminated

Evaluation of Resynchronization Therapy for Heart Failure (EARTH)

Heart Failure

Canada
National Jewish Health
National Heart, Lung, and Blood Institute (NHLBI); National Institutes of Health...

Completed

Tailored Treatment to Enhance Risk Perception in Sleep Apnea

Obstructive Sleep Apnea (OSA)

United States
National Institute of Mental Health (NIMH)

Recruiting

[18F]PF-06445974 to Image PDE4B in Major Depressive Disorder Using PET

Depression

United States
National Institute of Mental Health (NIMH)

Recruiting

Transcranial Magnetic Stimulation for Youth With Treatment-Resistant Major Depressive Disorder

Major Depressive Disorder

United States
American University
National Institute of Mental Health (NIMH); National Institutes of Health (NIH)

Recruiting

Cerebellum and Autism: Regional Specialization for Social and Executive Functions

Autism Spectrum Disorder | Autism

United States
National Institute of Mental Health (NIMH)

Recruiting

Long-term Observation of Participants With Mood Disorders

Depression | Suicide Risk

United States
National Institute of Mental Health (NIMH)

Recruiting

Role of GABAergic Transmission in Auditory Processing in Autism Spectrum Disorder

Autism Spectrum Disorder

United States
National Institute of Mental Health (NIMH)

Recruiting

PET Imaging of Cyclooxygenase in Participants With Major Depressive Disorder (MDD)

Depression

United States
National Institute of Mental Health (NIMH)

Recruiting

Effects of an ER Beta Agonist (Lilly Compound LY500307) on Estradiol-Withdrawal-Induced Mood Symptoms in Women With Past Perimenopausal Depression

Perimenopause-Related Depression

United States
National Institute of Mental Health (NIMH)

Recruiting

Neurobiology of Suicide

Depression | Healthy Volunteers

United States
National Institute of Mental Health (NIMH)

Recruiting

Checking Out Checking In: The Development and Validation of an Electronic Screening Tool for Pediatric Psychosocial Distress

Cancer

United States
National Institute of Mental Health (NIMH)

Recruiting

Brain Stimulation and Vision Testing

fMRI | Dorsal Pathway | Ventral Pathway

United States
National Institute of Mental Health (NIMH)

Recruiting

Functional Relevance of Dopamine Receptors in Healthy Controls and Patients With Schizophrenia: Characterization Through [11C]NNC-112 and [18F]Fallypride Positron Emission Tomography

Schizophrenia | Schizoaffective Disorder

United States
National Institute of Mental Health (NIMH)

Recruiting

The Neurodevelopmental and Behavioral Phenotyping Screening Protocol

Autism | Neurologic Disorders | Neurodegenerative Disease | Neurobehavioral Manifestation

United States
National Institute of Mental Health (NIMH)

Recruiting

MRS Measurement of Glutamate and GABA Metabolism in Brain

Normal Physiology

United States
National Institute of Mental Health (NIMH)

Recruiting

Studies of Brain Function and Course of Illness in Pediatric Bipolar Disorder

Mood Disorder

United States
National Institute of Mental Health (NIMH)
National Institutes of Health Clinical Center (CC)

Recruiting

Genetic Study of Schizophrenia

Schizophrenia | Schizoaffective Disorder

United States
National Institute of Mental Health (NIMH)

Completed

Studies of Frontal Lobe Brain Functioning in Schizophrenia

Schizophrenia | Parkinson Disease | Healthy Subjects

United States
National Institute of Mental Health (NIMH)

Active, not recruiting

Cognitive Neuroscience of Autism Spectrum Disorders

Children | Mental Retardation | Autism Spectrum Disorders | Asperger's Disorder | Adult

United States
National Institute of Mental Health (NIMH)

Completed

Perimenopause-Related Mood and Behavioral Disorders

Mood Disorder

United States
National Institute of Mental Health (NIMH)

Completed

Evaluation of a Novel PET Radioligand to Image Cyclooxygenase-1 (COX-1)

Normal Physiology

United States
National Institute of Mental Health (NIMH)

Terminated

[11C]-(R)-Rolipram to Measure cAMP Signaling Before and After Ketamine

Depression

United States
National Institute of Mental Health (NIMH)

Completed

[18F]SF12051 for Imaging the 18-kDa Translocator Protein (TSPO) in Brain and Whole Body of Healthy Subjects

Healthy

United States
National Institute of Mental Health (NIMH)

Completed

Impact on Anxiety and Motivation of COVID-19 and Predictors of Individual Responses

Anxiety | Healthy Volunteers

United States
National Institute of Mental Health (NIMH)

Completed

Cognitive vs. Emotional Psychopharmacological Manipulations of Fear vs. Anxiety

Anxiety Disorder

United States

Clinical Trials Sponsored by MGH Institute of Health Professions

Sponsors and Collaborators

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CROs in Italy

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Rare Diseases

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