Clinical Trials Sponsored by Pharmaceutical Research Network

Total 2618 results

SWOG Cancer Research Network
National Cancer Institute (NCI)

Active, not recruiting

Combination Treatment (Talazoparib Plus Avelumab) for Stage IV or Recurrent Non-Squamous Non-Small Cell Lung Cancer With STK11 Gene Mutation (A LUNG-MAP Treatment Trial)

Stage IVA Lung Cancer AJCC v8 | Stage IVB Lung Cancer AJCC v8 | Stage IV Lung Cancer AJCC v8 | Advanced Lung Non-Squamous Non-Small Cell Carcinoma | Recurrent Lung Non-Squamous Non-Small Cell Carcinoma

United States
SWOG Cancer Research Network
National Cancer Institute (NCI)

Active, not recruiting

S1602: Different Strains of BCG With or Without Vaccine in High Grade Non- Muscle Invasive Bladder Cancer

Stage 0is Bladder Urothelial Carcinoma | Stage I Bladder Urothelial Carcinoma | Stage 0 Bladder Urothelial Carcinoma

United States
SWOG Cancer Research Network
National Cancer Institute (NCI)

Active, not recruiting

Testing the Use of Combination Immunotherapy Treatment (N-803 [ALT-803] Plus Pembrolizumab) Against the Usual Treatment for Advanced Non-small Cell Lung Cancer (A Lung-MAP Treatment Trial)

Stage IVA Lung Cancer AJCC v8 | Stage IVB Lung Cancer AJCC v8 | Stage III Lung Cancer AJCC v8 | Stage IV Lung Cancer AJCC v8 | Stage IIIA Lung Cancer AJCC v8 | Stage IIIB Lung Cancer AJCC v8 | Stage IIIC Lung Cancer AJCC v8 | Advanced Lung Non-Small Cell Carcinoma | Recurrent Lung Non-Small Cell Carcinoma

United States
SWOG Cancer Research Network
National Cancer Institute (NCI)

Active, not recruiting

Lung-MAP: Nivolumab With or Without Ipilimumab as Second-Line Therapy in Treating Patients With Recurrent Stage IV Squamous Cell Lung Cancer and No Matching Biomarkers

Recurrent Squamous Cell Lung Carcinoma | Stage IV Squamous Cell Lung Carcinoma AJCC v7

United States, Canada
SWOG Cancer Research Network
National Cancer Institute (NCI)

Active, not recruiting

S0931, Everolimus in Treating Patients With Kidney Cancer Who Have Undergone Surgery (S0931)

Kidney Cancer

United States, Puerto Rico
SWOG Cancer Research Network
National Cancer Institute (NCI)

Active, not recruiting

S1403, Afatinib Dimaleate With or Without Cetuximab in Treating Patients With Newly Diagnosed Stage IV or Recurrent, EGFR Mutation Positive Non-small Cell Lung Cancer

Recurrent Non-Small Cell Lung Carcinoma | Stage IV Non-Small Cell Lung Cancer

United States
SWOG Cancer Research Network
National Cancer Institute (NCI)

Active, not recruiting

S1702 Isatuximab in Treating Patients With Relapsed or Refractory Primary Amyloidosis

Nausea | Constipation | Diarrhea | Purpura | Lymphadenopathy | Gastrointestinal Hemorrhage | Hepatomegaly | Primary Systemic Amyloidosis | Amorphous, Eosinophilic, and Acellular Deposit | Early Satiety | Macroglossia | Recurrent Primary Amyloidosis | Refractory Primary Amyloidosis

United States
SWOG Cancer Research Network
National Cancer Institute (NCI)

Active, not recruiting

Testing the Addition of Ruxolitinib to the Usual Treatment (Tyrosine Kinase Inhibitors) for Chronic Myeloid Leukemia

Chronic Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive

United States
European Myeloma Network
Sanofi; Amgen; EMN Research Italy

Active, not recruiting

Isa-KRd vs KRd in Newly Diagnosed Multiple Myeloma Patients Eligible for Autologous Stem Cell Transplantation (IsKia TRIAL) (IsKia)

Multiple Myeloma

Czechia, Germany, Greece, Italy, Netherlands, Norway, Spain
SWOG Cancer Research Network
Proteus Digital Health, Inc.

Terminated

S1916 Digital Medicine Program for Pain Control in Cancer Patients

Metastatic Cancer

United States
SWOG Cancer Research Network
National Cancer Institute (NCI)

Active, not recruiting

Treatment Effects on Development of Chemotherapy-Induced Peripheral Neuropathy in Patients With Cancer

Anatomic Stage I Breast Cancer AJCC v8 | Anatomic Stage IA Breast Cancer AJCC v8 | Anatomic Stage IB Breast Cancer AJCC v8 | Anatomic Stage II Breast Cancer AJCC v8 | Anatomic Stage IIA Breast Cancer AJCC v8 | Anatomic Stage IIB Breast Cancer AJCC v8 | Anatomic Stage III Breast Cancer AJCC v8 | Anatomic... and other conditions

United States, Colombia, Mexico, Chile
SWOG Cancer Research Network
National Cancer Institute (NCI)

Completed

Durvalumab and Tremelimumab in Treating Patients With Recurrent Stage IV Lung Cancer

Recurrent Squamous Cell Lung Carcinoma | Stage IV Squamous Cell Lung Carcinoma AJCC v7

United States
SWOG Cancer Research Network
National Cancer Institute (NCI)

Completed

Lung-MAP: Biomarker-Targeted Second-Line Therapy in Treating Patients With Recurrent Stage IV Squamous Cell Lung Cancer

Recurrent Squamous Cell Lung Carcinoma | Stage IV Squamous Cell Lung Carcinoma AJCC v7

United States, Canada
SWOG Cancer Research Network
National Cancer Institute (NCI)

Completed

S1314, Co-expression Extrapolation (COXEN) Program to Predict Chemotherapy Response in Patients With Bladder Cancer (COXEN)

Bladder Cancer

United States
SWOG Cancer Research Network
National Cancer Institute (NCI)

Completed

S0919 Idarubicin, Cytarabine, and Pravastatin in Treating Patients With Relapsed Acute Myeloid Leukemia

Leukemia

United States
Kern Pharma, S.L.
Analysis and Research Network, S.L

Unknown

Clinical Trial to Investigate the Effectiveness of a Dietary Supplement in Increasing Libido and Sexual Function in Postmenopausal Women.

Female Sexual Arousal Disorder

Spain
AOSpine North America Research Network
AOSpine North America

Completed

Assessment of Surgical Techniques for Treating Cervical Spondylotic Myelopathy (CSM)

Cervical Spondylotic Myelopathy

United States, Canada
Baylor Research Institute
Baylor University; JPS Health Network

Unknown

ED Overcrowding Validation Study (EDOVS)

Emergency Department Overcrowding
Dental PBRN Japan
Dental Practice-Based Research Network

Completed

Assessment of Caries Diagnosis and Caries Treatment in Dental PBRN Japan

Dental Caries
Accelerated Community Oncology Research Network
Bristol-Myers Squibb

Completed

Trial of Dasatinib Plus Ixabepilone in 2nd or 3rd Line Metastatic Breast Cancer

Metastatic Breast Cancer

United States
Trinitas Comprehensive Cancer Center
Aptium Oncology Research Network

Unknown

Guided Relaxation Training for the Reduction of Self-Reported Stress in Individuals With Newly Diagnosed Breast Cancer (09-IM-01)

Breast Cancer

United States
University Health Network, Toronto
Dystonia Medical Research Foundation

Unknown

Efficacy of Dronabinol for the Treatment of Cervical Dystonia

Cervical Dystonia

Canada
University Health Network, Toronto
Dystonia Medical Research Foundation

Unknown

Somatosensory Processing in Focal Hand Dystonia

Focal Hand Dystonia | Writer's Cramp | Musician's Dystonia | Dystonic Cramp

Canada
University of Nottingham
AstraZeneca; Cancer Research UK; National Cancer Research Network

Completed

AKT Inhibitor in Oestrogen Positive Breast Cancer (STAKT)

Invasive Breast Cancer

United Kingdom
Ottawa Hospital Research Institute
Canadian Institutes of Health Research (CIHR); Ontario HIV Treatment Network; CIHR Canadian HIV Trials Network

Completed

Combination Vaccination Before HIV Treatment Interruption

HIV Infections

Canada
HonorHealth Research Institute
Jazz Pharmaceuticals

Recruiting

Lurbinectedin in Patients With Advanced Gastrointestinal Malignancies With DNA Repair Mutations

Gastrointestinal Malignancies

United States
Cognitive Research Corporation
Novartis Pharmaceuticals

Withdrawn

Exploratory Study Evaluating the Effects of Darifenacin on Nocturia, Sleep and Daytime Wakefulness

Nocturia
McGuire Research Institute
Solvay Pharmaceuticals

Completed

Effect of Testosterone Replacement on Insulin Resistance

Metabolic Syndrome | Hypogonadism

United States
Provident Clinical Research
Reliant Pharmaceuticals

Completed

An Evaluation of Simvastatin Plus Omacor Compared to Simvastatin Plus Placebo in Subjects With Mixed Dyslipidemia

Mixed Dyslipidemia
Pacylex Pharmaceuticals
Ozmosis Research Inc.

Recruiting

Phase I Trial of PCLX-001 in R/R Advanced Solid Malignancies and B-cell Lymphoma

Advanced Solid Tumor | B-cell Non Hodgkin Lymphoma

Canada
Buzzard Pharmaceuticals
Baylor Research Institute

Recruiting

Isunakinra Alone and in Combination With a PD-1/PD-L1 Inhibitor in Patients With Solid Tumors

Solid Tumor, Adult

United States
HonorHealth Research Institute
Cantex Pharmaceuticals

Terminated

Disulfiram-Copper Gluconate in Met Pancreas Cancer w Rising CA19-9 on Abraxane-Gemzar, FOLFIRINOX or Gemcitabine

Metastatic Pancreatic Cancer

United States
Unither Pharmaceuticals, France
Raptim Research

Completed

Pharmacokinetic Study of Paracetamol UNIFLASH (125 MG/1.25 ML)

Acute Pain

India
US Oncology Research
Novartis Pharmaceuticals

Completed

STAR Cape+BKM120 MBC With Brain Met

Breast Cancer | Metastatic Breast Cancer | Brain Metastases

United States
DMR Research, PLLC
Endo Pharmaceuticals

Completed

To Assess the Effectiveness of Multiple Dose, Multiple Concentrations of Qwo, for the Treatment of Mild to Moderate Cellulite.

Cellulite

United States
Innovaderm Research Inc.
Tribute Pharmaceuticals

Completed

Pilot Study on the Use of Acitretin for the Treatment of Severe Chronic Hand Dermatitis

Chronic Hand Dermatitis

Canada
Meda Pharmaceuticals
TKL Research, Inc.

Completed

Open Label Safety Study of Xerese Cream in the Treatment of Recurrent Herpes Labialis in Children 6-11 Years Old

Herpes Labialis

United States
Imprimis Pharmaceuticals, Inc.
Cato Research

Completed

Ketoprofen 10% Cream for Treatment of Pain Associated With Mild to Moderate Acute Soft Tissue Injury

Sprain | Strain | Acute Soft Tissue Injury

United States
Cancer Research Antwerp
Janssen Pharmaceutica

Recruiting

Radiotherapy Combined With a LHRH (Ant)Agonist Versus Apalutamide in Patients With Biochemical Recurrence After RP (SAVE)

Cancer of Prostate

Belgium
Idorsia Pharmaceuticals Ltd.
Carelon Research

Active, not recruiting

Database Study to Provide Information on Pregnancy and Infant Outcomes Among Women Exposed to QUVIVIQ (Daridorexant)

Insomnia Disorder

United States
Concert Pharmaceuticals
Cognitive Research Corporation

Completed

A Phase 2 Study to Evaluate the Safety and Efficacy of CTP-692 as an Adjunctive Treatment in Adults With Schizophrenia

Schizophrenia

United States
US Oncology Research
Novartis Pharmaceuticals

Completed

Miracle Mouthwash Plus Hydrocortisone vs Prednisolone Mouth Rinse for Mouth Sores Caused by Everolimus

Stomatitis | Oral Mucositis | Malignant Tumor of Breast | Neoplasm of the Breast

United States
Torrent Pharmaceuticals Limited
Catawba Research

Completed

Study Comparing Test to Aczone 7.5% and Both to a Placebo Control in the Treatment of Acne Vulgaris

Acne Vulgaris

United States, Belize
Baylor Research Institute
Regeneron Pharmaceuticals

Unknown

Alirocumab in Patients on a Stable Dialysis Regimen

Hemodialysis | Peritoneal Dialysis | Hypercholesterolemia | Atherosclerotic Disease

United States
Arrowhead Pharmaceuticals
ICON Clinical Research

Terminated

A Multicenter Study to Determine the Depth and Duration of Hepatitis B Surface Antigen (HBsAg) Reduction After Single or Multiple Doses of ARC-520, in Combination With Entecavir in Patients With Chronic Hepatitis B Virus (HBV) Infection

Hepatitis B, Chronic

Hong Kong
Vanda Pharmaceuticals
Cross Research S.A.

Completed

Study to Assess the Effect of Multiple Doses of Tradipitant on CYP3A4 Using Midazolam as a Substrate in Healthy Subjects

Healthy Volunteers

Switzerland
Provident Clinical Research
Reliant Pharmaceuticals

Unknown

An Open-Label Extension to Assess the Continued Efficacy of Omacor Plus Simvastatin

Mixed Dyslipidemia
University Health Network, Toronto
Canadian Institutes of Health Research (CIHR); CIHR Canadian HIV Trials Network

Completed

Structured Treatment Interruption for HIV Patients With Virologic Failure

HIV
University College Cork
Health Research Board, Ireland; Health Research Board - Trials Methodology...

Completed

Enhancing Men's Awareness of Testicular Diseases (E-MAT): A Feasibility Trial (E-MAT)

Testicular Diseases

Ireland
Fujirebio Diagnostics, Inc.
Medical Research Networx LLC

Terminated

A Prospective Longitudinal Collection of Subjects Diagnosed With Small Cell Lung Cancer

Small Cell Lung Cancer

United States

Clinical Trials Sponsored by Pharmaceutical Research Network

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