Clinical Trials Sponsored by SPARK Biopharma

Total 2240 results

Can-Fite BioPharma

Completed

A Phase 1-2 Study of CF102 in Patients With Advanced Hepatocellular Carcinoma

Hepatocellular Carcinoma

Israel
AiViva BioPharma, Inc.

Withdrawn

A Safety and Efficacy Study to Evaluate Rosacea

Papulopustular Rosacea

United States
AiViva BioPharma, Inc.

Completed

Effect of Intravitreally Administered AIV007 in Subjects With nAMD

Neovascular Age-related Macular Degeneration

United States
Landos Biopharma Inc.

Completed

Safety, Tolerability and Pharmacokinetics of Oral NX-13 in Healthy Adults Male and Female Volunteers

Ulcerative Colitis

Australia
Theravance Biopharma
GlaxoSmithKline

Completed

Study of GSK961081 in Healthy Volunteer Subjects

Pulmonary Disease, Chronic Obstructive

United Kingdom
Denovo Biopharma LLC

Withdrawn

A Study of LY2140023 in Healthy Participants

Healthy Participants

Switzerland
Hansa Biopharma AB

Completed

A Phase II Study to Evaluate the Efficacy of IdeS to Desensitize Transplant Patients With a Positive Crossmatch Test (Highdes)

Kidney Failure, Chronic

United States, Sweden, France
Fountain Biopharma Inc.

Completed

An Open-Labeled Exploratory Study to Evaluate Safety and Efficacy of FB825 in Adults With Atopic Dermatitis

Atopic Dermatitis

Taiwan
Can-Fite BioPharma

Completed

Trial of CF101 to Treat Patients With Psoriasis

Plaque Psoriasis

Israel, United States, Bulgaria, Romania
Matinas Biopharma, Inc

Completed

A PK and PD Study of Two Formulations of Omega-3 One Gram Capsules (PK/PD)

Hypertriglyceridemia

Canada
Mereo BioPharma
Novartis

Terminated

Safety and Efficacy of BGS649 in Obese, Hypogonadotropic Hypogonadal Men (OHH)

Obese Hypogonadotropic Hypogonadism

United States, Canada
Civi Biopharma, Inc.

Completed

A First In Human Study to Assess CiVi007 in Subjects With an Elevated LDL-Cholesterol Level

Hypercholesterolemia

United Kingdom
Ansun Biopharma, Inc.

Withdrawn

DAS181 for STOP COVID-19

COVID-19

Italy
RedHill Biopharma Limited

Withdrawn

Treatment of COVID-19 With Opaganib in Patients With Pneumonia Requiring Oxygen (Opaganib-RHB)

COVID-19 | Lung Infection

Israel
Ansun Biopharma, Inc.

Unknown

DAS181 for Patients With Severe Hospitalized Flu and SAD-RVs (COVID-19) (STOP-Flu)

Influenza Infection | SAD-RV Infection and COVID-19

China
Can-Fite BioPharma

Completed

A Study of the Efficacy and Safety of CF102 in the Treatment of Non-Alcoholic Fatty Liver Disease

Non-alcoholic Steatohepatitis (NASH)

Israel
Takeda
Theravance Biopharma

Completed

A Randomized, Double-Blind Study to Evaluate the Safety, Tolerability, and Pharmacodynamics of a Single Dose of Intravenous TD-8954 Compared With Metoclopramide in Critically Ill Patients With Enteral Feeding Intolerance

Enteral Feeding Intolerance

Australia
Janssen BioPharma, Inc.

Completed

A First-In-Human Study of Orally Administered JNJ-64417184 to Evaluate the Safety, Tolerability, and Pharmacokinetics of Single and Multiple Ascending Doses, and the Antiviral Activity of Multiple Doses in a Respiratory Syncytial Virus (RSV) Challenge Study in Healthy Participants

Healthy

United Kingdom
Acrotech Biopharma Inc.

Completed

Comprehensive Oncology Measures for Peripheral T-cell Lymphoma Treatment Registry (COMPLETE)

Peripheral T-cell Lymphoma

United States
Acrotech Biopharma Inc.

Completed

Phase 1 Dose Finding Study of Belinostat for Treatment of Patients With Peripheral T-cell Lymphoma (PTCL)

Peripheral T-cell Lymphoma

United States
Acrotech Biopharma Inc.

Completed

Phase I Mass Balance, PK and Safety Study of 14C-Labeled Belinostat in Patients With Advanced Cancer

Advanced Cancer

Spain
Acrotech Biopharma Inc.

Completed

Study of Pralatrexate With Vitamin B12 and Folic Acid in Patients With Relapsed or Refractory Peripheral T-cell Lymphoma (PROPEL)

Peripheral T-cell Lymphoma

United States, United Kingdom, Canada, France, Italy, Belgium
Acrotech Biopharma Inc.

Completed

PK Study of Melphalan HCL & Alkeran for Injection of MA Conditioning in MM Patients of Autologous Transplantation

Multiple Myeloma

United States
Acrotech Biopharma Inc.

Completed

Pharmacokinetic Study of Liposomal Vincristine in Patients With Malignant Melanoma & Hepatic Dysfunction

Malignant Melanoma

United States
Alios Biopharma Inc.

Completed

A Study of Orally Administered JNJ-440 to Evaluate the Safety, Tolerability, and Pharmacokinetics After Single Ascending Doses Including Food Effect Evaluation; After Multi-Day Dosing in Healthy Participants; and After Multiple (Ascending) Doses in Participants With Chronic Hepatitis B

Chronic Hepatitis B

Korea, Republic of, Moldova, Republic of, New Zealand, Thailand, Ukraine
Oncolys BioPharma Inc

Unknown

A Dose-Escalation Study of OBP-801 in Patients With Advanced Solid Tumors

Solid Tumor

United States
Micelle BioPharma Inc

Unknown

Dose-Finding Study of SC411 in Children With Sickle Cell Disease (SCOT)

Sickle Cell Disease

United States
Veloce BioPharma LLC

Completed

A Trial to Evaluate the Efficacy and Safety of Two Concentrations of VBP-926 Solution for the Treatment of Chemotherapy-associated Paronychia in Cancer Patients

Chemotherapy-Associated Paronychia

United States
Arbutus Biopharma Corporation

Completed

A Dose Finding Study of TKM-080301 Infusion in Neuroendocrine Tumors (NET) and Adrenocortical Carcinoma (ACC) Patients

Cancer | Neuroendocrine Tumors | Adrenocortical Carcinoma | ACC | NET

United States
Can-Fite BioPharma

Withdrawn

Safety &Efficacy of CF101 to Subjects With Uveitis

Uveitis, Posterior | Uveitis, Intermediate

Israel
Alios Biopharma Inc.

Completed

Study of Single and Multiple Doses of ALS-008176 in Healthy Volunteers

Respiratory Syncytial Virus Infections

France
Alios Biopharma Inc.

Terminated

A First in Human Study of AL-611 in Healthy Volunteers and Patients With Hepatitis C Virus Infection

Hepatitis C

Belgium
Alios Biopharma Inc.

Withdrawn

A Study Evaluating AL-3778 in Combination With Peginterferon Alpha-2a in Chronic Hepatitis B Subjects

Hepatitis B, Chronic
Ansun Biopharma, Inc.

Completed

An Open Label Study to Examine the Effects of DAS181 Administered by Dry Powder Inhaler (DPI) or Nebulized Formulation in Immunocompromised Subjects With Parainfluenza (PIV) Infection (PIV)

Parainfluenza

United States
Galena Biopharma, Inc.

Completed

A Study of Anagrelide Controlled Release (GALE-401) in Patients With High Platelet Counts Due to Bone Marrow Disorders

Thrombocytosis | Myeloproliferative Neoplasms

United States
Soricimed Biopharma Inc

Completed

Safety and Tolerability Study of SOR-C13 in Subjects With Advanced Cancers Commonly Known to Express the TRPV6 Channel

Cancer

Canada, United States
Galena Biopharma, Inc.

Completed

Observational Registry Study of Quality of Life When Treating BTcP With Abstral (RELIEF)

Quality of Life | Breakthrough Cancer Pain

United States
Can-Fite BioPharma

Completed

A Phase 1/2 Study of CF102 in Patients With Chronic Hepatitis C Genotype 1

Chronic Hepatitis C

Israel
iX Biopharma Ltd.

Completed

Study of Ketamine Administered Intravenously and by Sublingual Wafer

Pain

Australia
CeNeRx BioPharma Inc.

Completed

Oral Tyramine Pressor Response Study of CX157 Tablets in Healthy Male Volunteers (CX157-112)

Major Depressive Disorder

United States
Lytix Biopharma AS

Completed

A Phase I/IIa Study to Evaluate the Safety, Tolerability and Efficacy of Topical LTX-109 in Subjects Nasally Colonized With Methicillin-resistant/-Sensitive Staphylococcus Aureus (MRSA/MSSA)

Nasal Carriers MRSA

Sweden
Ambrilia Biopharma, Inc.

Terminated

Safety and Biological Activity of C2L-OCT-01 PR in Acromegalic Patients

Acromegaly

United States, Belarus, Hungary, Serbia, Ukraine, Romania
Ambrilia Biopharma, Inc.

Completed

Efficacy and Safety of C2L-OCT-01 PR in Acromegalic Patients

Acromegaly

Belarus, Hungary, Romania, Serbia, Slovakia, Ukraine
ARCA Biopharma, Inc.

Completed

Safety and Efficacy Study of Alfimeprase in Subjects With Occluded Catheters

Thrombosis | Venous Thrombosis | Catheter Occlusion

United States
ARCA Biopharma, Inc.

Completed

Safety and Efficacy Study of Alfimeprase in Subjects With Occluded Central Catheters

Thrombosis | Venous Thrombosis

United States
WestVac Biopharma Co., Ltd.
WestVac Biopharma (Guangzhou) Co., Ltd.

Recruiting

A Phase 3 Clinical Study to Evaluate the Efficacy, Safety and Immunogenicity of Booster Vaccination With Recombinant COVID-19 (XBB) Trimer Protein Vaccine (Sf9 Cell)

COVID-19

China
BioPharmX, Inc.

Completed

Open Label Photo-Documentation Study Of BPX-01 Minocycline Gel

Acne Vulgaris

United States
BioPharmX, Inc.

Unknown

Topical Minocycline Gel for Inflammatory Lesions of Papulopustular Rosacea (PRISM)

Papulopustular Rosacea

United States
BioPharmX, Inc.

Completed

Administration of Oral Extended Release Minocycline for Assessment of Skin and Plasma Concentrations of Minocycline

Acne

United States
BioPharmX, Inc.

Completed

Open Label Phase 2 Feasibility Study of BPX-04 Topical Minocycline Gel in Rosacea

Moderate to Severe Papulopustular Rosacea

United States

3

Subscribe