Search clinical trials for: Aquired resistance to EGFR TKI

Total 476929 results

Cairo University

Not yet recruiting

Antibiotics, Antibiotic Resistance, and Prescribing Practices Among Periodontists: Cross Sectional KAP Study

Periodontitis | Antibiotic Resistance | Antibiotic Use
Region Skane
Lund University

Not yet recruiting

Screening of Multidrug Resistant Bacteria, and the Clinical Implication for the Patient

Multi-antibiotic Resistance
Lawson Health Research Institute
Greenstone Biosciences, Inc.

Recruiting

iPSC Biobank of Biomarkers Diversity in Cardiovascular Disease (INFERENCE)

Cardiovascular Diseases | Heart Failure | Cardiomyopathies | Congenital Heart Disease | Cerebrovascular Accident | Arrythmia | Cardiometabolic Syndrome

Canada
M.D. Anderson Cancer Center

Not yet recruiting

Open-label Phase 2 Study of Avutometinib (RAF/MEK Clamp) in Combination With Defactinib (FAK Inhibitor) and Cetuximab in Patients With Unresectable, Anti-EGFR-Refractory Advanced Colorectal Cancer

Advanced Colorectal Cancer

United States
Universidad de La Frontera

Not yet recruiting

Resistance Exercise Training in the Older Population With Obesity (RETOPO)

Obesity | Aging

Chile
University of Utah

Recruiting

The Acute T-Rex (Timing of Resistance Exercise) Study

Diabetes Mellitus, Type 2 | Insulin Resistance | Glucose Intolerance | Sleep Disturbance | Overweight or Obesity | Insulin Sensitivity

United States
Medical College of Wisconsin

Not yet recruiting

Molecular Analyses to Identify Pathways of Endocrine Resistance Following Short Term Neoadjuvant Endocrine Treatment in Patients With Hormone Receptor-Positive HER2-negative Breast Cancer

Breast Cancer

United States
Peking Union Medical College Hospital

Recruiting

Combination of Cardonizumab Injection and TKI Second Line Therapy for Advanced Hepatocellular Cancer

Hepatocellular Carcinoma

China
Leeuwenhoek Laboratories Co. Ltd.

Not yet recruiting

Investigation of Metabolomics Differences Between Metabolic Syndrome and Healthy Individuals in Taiwan

Metabolic Syndrome
National Cancer Center, China

Not yet recruiting

A Study With BPI-1178 and Osimertinib in Advanced Non-small Cell Lung Cancer Patients With EGFR Mutations (EGFR)

NSCLC
Sengkang General Hospital
Singapore General Hospital; Duke-NUS Graduate Medical School; Lee Kong Chian...

Recruiting

Pilot Study of the Human Metagenome in Metabolic Diseases

Obesity | Metabolic Syndrome | Sarcopenia | Chronic Inflammation | Sarcopenic Obesity

Singapore
Assiut University

Not yet recruiting

Association Between Triglycerides Glucose Ratio With HOMA -IR as Indicators of Insulin Resistance in Obese Adults

Insulin Resistance
University of California, San Francisco
Bill and Melinda Gates Foundation; Ministère de la Santé Publique du Niger; Centre... and other collaborators

Not yet recruiting

Azithromycin for Child Survival in Niger II (AVENIR II)

Mortality | Antimicrobial Resistance

Niger
University Hospital, Montpellier

Not yet recruiting

Plasma Biomarkers of Muscle Metabolism During Exercise to the Assessment of Insulin Resistance in CKD Dialysis Patients (KREBSome-IRC)

Metabolic Syndrome | Dialysis; Complications

France
University of Alabama at Birmingham
National Institute on Minority Health and Health Disparities (NIMHD)

Not yet recruiting

Remotely Delivered Resistance Training for Cardiometabolic Health Among Black Women (OVERCOME-IT)

Overweight or Obesity | Resistance Training | Prediabetes or Diabetes | Prehypertension (Elevated Blood Pressure) or Hypertension

United States
University Ghent
University Hospital, Ghent

Recruiting

Effect of High Intensity Exercise Rehabilitation on Liver Function and Insulin Sensitivity in Patients With MASLD (CENSORIAL)

Exercise Therapy | Metabolic Dysfunction-associated Steatotic Liver Disease

Belgium
University of Utah

Not yet recruiting

Topical Tretinoin Prophylaxis for Anti-EGFR Induced Skin Toxicity in Metastatic Colorectal Cancer (FACE)

Metastatic Colon Cancer | Metastatic Rectum Cancer

United States
Imperial College London
The Behavioural Insights Team

Not yet recruiting

Testing New Ways to Name Antimicrobial Resistance

Antimicrobial Resistance | Attitude to Health
Fudan University

Not yet recruiting

Inosine Reverse Chemo Resistance in Triple Negative Breast Cancer

Triple-negative Breast Cancer
College of Staten Island, the City University of...
Bay Ridge Center

Not yet recruiting

Hydraulic Resistance and Older Adults

Muscle Weakness | Aging | Fall | Old Age; Debility

United States
Federation Francophone de Cancerologie Digestive

Recruiting

Prospective Cohort Study of Immunotherapy Resistance in Metastatic Colorectal Cancer Patients With MSI (CORESIM)

Colorectal Cancer Metastatic | Microsatellite Instability-High Colorectal Cancer

France
Integrative Phenomics
Assistance Publique - Hôpitaux de Paris; Assistance Publique Hopitaux De Marseille and other collaborators

Not yet recruiting

Individual Factors Related to Chronic Low-grade Inflammation and Cardiometabolic Disease Risk (PINEAPPL)

Hypertension | Healthy | Obesity | Overweight | Metabolic Syndrome | Hypercholesterolemia | Risk Factor, Cardiovascular | Abdominal Obesity | Normal Weight Adults | Low-grade Inflammation | Metabolically Healthy Controls
Hunan Province Tumor Hospital

Not yet recruiting

Sunvozertinib Plus Anlotinib as 1L Treatment in EGFR Mutant Advanced NSCLC-RW (WUKONG-32-RW)

Non-small Cell Lung Cancer

China
Columbia University
University of California, Berkeley

Recruiting

Human Models of Selective Insulin Resistance: Alpelisib, Part I

Insulin Resistance | Prediabetic State | Overweight and Obesity | Non-Alcoholic Fatty Liver Disease

United States
Fudan University

Not yet recruiting

Dasatinib Combined With Quercetin to Reverse Chemo Resistance in Triple Negative Breast Cancer

Triple-negative Breast Cancer
Tang-Du Hospital

Recruiting

An Observational Study of Furmonertinib for EGFR Mutation-positive NSCLC Patients With Brain Metastasis

EGF-R Positive Non-Small Cell Lung Cancer | CNS Metastases

China
SpeeDx Pty Ltd
German Federal Ministry of Education and Research; Wellcome Trust; Biomedical... and other collaborators

Not yet recruiting

Susceptibility Testing In Neisseria Gonorrhoeae (STING) Study, Assessing the Performance of a New Rapid Test for Gonorrhoea Antibiotic Resistance, in a Cohort of 100 Culture Positive Neisseria Gonorrhoeae Infections (STING)

Gonorrhea | Diagnosis | Resistance Bacterial
Iman Al-Naggar, PhD
National Institute on Aging (NIA); American Urological Association; Urology Care... and other collaborators

Recruiting

Testing MitoQ on Lower Urinary Tract Symptoms in Older Women With Metabolic Syndrome (Mito-LUTS)

Lower Urinary Tract Symptoms | Overactive Bladder Syndrome

United States
Rowan University

Recruiting

Project WHADE: A Partner-Based Physical Activity Program for Women

Smoking | Hypertension | Metabolic Syndrome | PreDiabetes | Prehypertension | Type 2 Diabetes | High Cholesterol

United States
Hunan Province Tumor Hospital

Not yet recruiting

Sunvozertinib Plus Anlotinib as 1L Treatment in EGFR-Sensitive Mutations Combined With Co-Mutations Advanced NSCLC (WUKONG-32)

Non-Small Cell Lung Cancer

China
Queen's University

Recruiting

Evaluating Changes in Skeletal Muscle Proteins Following Resistance Exercise and Single-Leg Disuse

Healthy | Skeletal Muscle Atrophy | Skeletal Muscle Hypertrophy

Canada
Beni-Suef University

Recruiting

Phosphodiesterase Type 5 Inhibitors in Patients With Group 2 Pulmonary Hypertension

Group 2 Pulmonary Hypertension

Egypt
Bayer

Recruiting

A Study to Learn About How Itraconazole and Carbamazepine Affect the Level of BAY2927088 in the Blood When These Drugs Are Taken Together by Healthy Participants

Healthy Volunteers | Advanced Non-small Cell Lung Cancer | EGFR Mutation | HER2 Mutation

United States
AstraZeneca
Daiichi Sankyo

Recruiting

Phase III, Open-label Study of First-line Osimertinib With or Without Datopotamab Deruxtecan for EGFRm Locally Advanced or Metastatic Non-small Cell Lung Cancer (TROPION-Lung14)

Non-small Cell Lung Cancer

Australia, China, Korea, Republic of, Taiwan
Infectious Diseases Research Collaboration, Uganda
London School of Hygiene and Tropical Medicine; Radboud University Medical...

Not yet recruiting

The Transmission of Artemisinin Resistant Parasites Before and After Conventional Artemisinin-combination Therapy (SPARTAN)

Falciparum; Malaria

Uganda
Roswell Park Cancer Institute

Recruiting

Genetically Engineered Cells (EGFRt/19-28z/IL-12 CAR T Cells) for the Treatment of Relapsed or Refractory CD19+ Hematologic Malignancies

Recurrent Mantle Cell Lymphoma | Recurrent Diffuse Large B-Cell Lymphoma | Refractory Diffuse Large B-Cell Lymphoma | Refractory Chronic Lymphocytic Leukemia | Refractory Mantle Cell Lymphoma | Recurrent High Grade B-Cell Lymphoma | Recurrent Transformed Follicular Lymphoma to Diffuse Large B-Cell... and other conditions

United States
University of Texas Southwestern Medical Center
National Institute on Minority Health and Health Disparities (NIMHD)

Recruiting

Socioecological Factors Associated With Ethnic Disparities in Bariatric Surgery Utilization and Post-WLS

Obesity | Metabolic Syndrome

United States
Assistance Publique - Hôpitaux de Paris

Not yet recruiting

Randomized Controlled Trial in Patients on Long-term Colchicine With Colchicine-resistant Familial Mediterranean Fever (FMF) to Evaluate the Efficacy of On-demand Anakinra Treatment for Painful Attacks in Patients Who Refuse Continuous Daily Therapy (KIN-ATTACK-FMF)

FMF

France
National Geriatric Hospital

Not yet recruiting

Results of Progressive Resistance Training in Older Type 2 Diabetic Patients With Sarcopenia

Diabetes | Sarcopenia

Vietnam
Methodist Health System

Recruiting

Antimicrobial Resistance During the SARS-CoV-2 (COVID-19) Pandemic

COVID-19

United States
University of Valencia
Generalitat Valenciana

Recruiting

Metabolic Flexibility and Autonomic Control After Muscle Power vs Metabolic Power Training in Postmenopausal Oncological Women: the POWER Health Study (POWER Health)

Breast Cancer Female | Autonomic Dysfunction | Cardiovascular Diseases in Old Age | Cardiometabolic Syndrome | Metabolism Disorder, Lipid

Spain
Mahidol University

Not yet recruiting

The Efficacy of Pedometer-motivated Physical Activity for the Management of Patients With MASLD.

BMI | Metabolic Syndrome | Insulin Resistance | NAFLD | Genetic Polymorphism | Cardiovascular Disease (CVD) | MASLD | Daily Step Count
Defence Medical Rehabilitation Centre, UK
University of Bath

Recruiting

Acute Physiological Responses to Twice Daily Blood Flow Restriction Training

Muscle Weakness | Muscle Damage

United Kingdom
Bayer

Recruiting

A Study to Learn About How BAY2927088 Affects the Level of Dabigatran or Rosuvastatin in the Blood When These Drugs Are Taken Together in Healthy Participants

Healthy Volunteers | Advanced Non-small Cell Lung Cancer | EGFR Mutation | HER2 Mutation

United Kingdom
Institute for Clinical and Experimental Medicine

Not yet recruiting

Mechanisms of Pulmonary Vascular Dysfunction in Heart Failure (LUNG-HF)

Heart Failure | Pulmonary Hypertension | Pulmonary Vascular Resistance Abnormality

Czechia
Samsung Medical Center

Recruiting

The Resistance Mechanism of Trastuzumab Deruxtexan in HER2 Positive Breast Cancer Patients.

HER2-positive Breast Cancer

Korea, Republic of
University of Aarhus

Recruiting

Exercise as Treatment of Fatigue in Parkinson´s Disease

Parkinson's Disease

Denmark
McGill University Health Centre/Research Institute...
Dairy Farmers of Canada

Not yet recruiting

Effect of Dairy Product Matrices on Insulin Resistance in People With Overweight and Obesity and Prediabetes

PreDiabetes | Overweight and Obesity

Canada
Dana-Farber Cancer Institute
Breast Cancer Research Foundation

Recruiting

Resistance and Aerobic Exercise for Prevention in Women With Dense Breasts (REP-D)

Breast Cancer | Breast Cancer Female

United States
Fudan University

Not yet recruiting

Adjuvant Target Therapy Guided by ctDNA-MRD in Patients With EGFR-mutant II-IIIA Non-small Cell Lung Cancer (ECTOP-1022)

Lung Cancer | Minimal Residual Disease | EGFR Gene Mutation

Search clinical trials for: Aquired resistance to EGFR TKI

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