Search clinical trials for: Bioavailability, Pharmacokinetics

Total 10348 results

Yale University
National Institute on Drug Abuse (NIDA); VA Connecticut Healthcare System

Recruiting

PK/PD of Oral and Vaporized Delta-9-Tetrahydrocannabinol (THC) in Older Adults

Pain, Tolerance | Oral vs Vaporized THC | Abuse Liability

United States
Ikaria Bioscience Pty Ltd

Recruiting

Adult Subjects With Elevated Low-Density Lipoprotein-Cholesterol to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamic Effects

To Reduce the LDL-C Level in Hypercholesteremia Adult Patients | Combination for Subgroup High LDL-c Patients With Other Comorbidities

Australia
BeiGene

Recruiting

A Study Investigating the Safety, Tolerability, Pharmacokinetics, and Preliminary Antitumor Activity of BGB-30813

Advanced Solid Tumors

United States, Australia, Spain
Ryazan State Medical University

Recruiting

Clinical One-stage Controlled Study of reSistant Arterial Hypertension for the desiGning of a personAlized Approach to Therapy (SAGA)

Resistant Arterial Hypertension

Russian Federation
GeneScience Pharmaceuticals Co., Ltd.
Afﬁliated Hospital of North Sichuan Medical College

Recruiting

Clinical Study of Multiple Dose Genakumab for Injection in Chinese Healthy Adults

Interstitial Lung Disease

China
Peking University Third Hospital

Recruiting

Pharmacokinetics of Clinical Probes and Characteristics of Endogenous Biomarker in Chinese Older Adults

Aging

China
Bill & Melinda Gates Medical Research Institute

Recruiting

Safety, Tolerability, Pharmacokinetics and Protective Efficacy of MAM01 in Healthy Adults

Malaria

United States
Eli Lilly and Company

Recruiting

A Study of LY3502970 in Participants With Impaired and Normal Liver Function

Hepatic Insufficiency | Healthy

United States
Bio-Thera Solutions
Zhejiang Tumor Hospital

Recruiting

To Evaluate the Safety, Tolerance and Pharmacokinetics of BAT8007 for Injection in Patients With Advanced Solid Tumors

Advanced Solid Tumors

China
Johns Hopkins University
DEKA S.r.l.

Not yet recruiting

Blood Naloxone Levels Following Intradermal Injection in Humans

Opioid Overdose
The Second Affiliated Hospital of Chongqing Medical...

Recruiting

Precision Drug Use of Immunosuppressants Guided by Population Pharmacokinetics/Pharmacodynamic Models in Kidney Transplant Patients

Kidney Transplantation | Immunosuppressive Agents

China
Genentech, Inc.
Chugai Pharmaceutical Co.

Recruiting

A Study to Evaluate the Safety, Pharmacokinetics, and Activity of RO7496353 in Combination With a Checkpoint Inhibitor With or Without Standard-of-Care Chemotherapy in Participants With Locally Advanced or Metastatic Solid Tumors

Gastric Cancer | Metastatic Solid Tumor | Non-small Cell Lung Cancer | Pancreatic Ductal Adenocarcinoma

Korea, Republic of, Spain, Japan, New Zealand, Australia, United States, Italy, Brazil
Aneira Pharma, Inc.
DataPharm Australia, CMAX Clinical Research, Agilex Australia

Not yet recruiting

Phase I Study of Safety and Pharmacokinetics of Topical Solution in Subjects With Androgenetic Alopecia

Androgenetic Alopecia
Vertex Pharmaceuticals Incorporated

Recruiting

A Study to Evaluate Pharmacokinetics (PK) and Safety of Inaxaplin in Participants With Renal Impairment

Renal Impairment

United States
HighField Biopharmaceuticals Corporation

Recruiting

A Clinical Study to Investigate the Safety, Tolerability, Pharmacokinetics, Immunogenicity and Preliminary Efficacy of HF158K1 in Participants With HER-2 Positive or HER-2 Low Expression Advanced Solid Tumors

Solid Tumors, Adult

China, United States
Afimmune

Recruiting

Pharmacokinetics, Pharmacodynamics and Safety of Epeleuton in Patients With Sickle Cell Disease

Sickle Cell Disease

United States
Radboud University Medical Center

Recruiting

Pharmacokinetic Study of Minocycline in Patients With Pulmonary Nontuberculous Mycobacterial Disease (Mino-PK)

Mycobacterium Avium Complex Pulmonary Disease

Netherlands
Centre Henri Becquerel
Universitaire Ziekenhuizen KU Leuven; Erasmus Medical Center

Not yet recruiting

Influence of Body Composition on Chemotherapy Outcomes in Localized Breast Cancer (FATTAX)

Breast Cancer

France
Luye Pharma Group Ltd.

Not yet recruiting

Pharmacokinetics Pharmacodynamics and Safety of LY01022 in Patients With Prostate Cancer Compared With Zoladex® 10.8mg

Prostate Cancer

China
Zhaoke (Hong Kong) Ophthalmology Pharmaceutical...

Recruiting

A Study of Atropine Sulfate in Healthy Chinese Volunteers

Pharmacokinetics

China
Ain Shams University
Cairo University

Recruiting

Pharmacokinetics, Safety, Efficacy and Acceptability of Daclatasvir Plus Sofosbuvir in HCV-infected Children

HCV

Egypt
First People's Hospital of Hangzhou

Recruiting

Study of Tenofovir Alafenamide in HBV-Infected Pregnant Women

Chronic Hepatitis b | Tenofovir Alafenamide Fumarate

China
Bio-Thera Solutions

Recruiting

Assessment of Safety, Tolerability and Pharmacokinetics With BAT8010 for Injection in Advanced Malignant Solid Tumors Patients

Advanced or Metastatic Solid Tumors

China
Biotheus Inc.

Recruiting

A Study of PM8002 (Anti-PD-L1/VEGF) in Combination With Chemotherapy in Patients With ES-SCLC

SCLC

China
Servier Bio-Innovation LLC
Institut de Recherches Internationales Servier

Recruiting

A Phase 1, Open-Label Study to Evaluate the Effect of a Low-Fat Meal and Multiple Doses of Ciprofloxacin on the Pharmacokinetics of Vorasidenib in Healthy Subjects

Healthy Subjects

United States
Washington State University
National Center for Complementary and Integrative Health (NCCIH)

Recruiting

Evaluating a Potential Pharmacokinetic Kratom-oxycodone Interaction Concurrent With Clinical Endpoints

Herbal Interaction

United States
University Medicine Greifswald

Recruiting

Sex Differences in Berberine Pharmacokinetics (BERKI-2)

Pharmacokinetic Study in Healthy Volunteers

Germany
Vir Biotechnology, Inc.

Recruiting

A Study to Investigate the Effect of Renal Impairment on the Pharmacokinetics and Safety of VIR-2218

Renal Impairment

United States
University of Ulster
Federico II University

Recruiting

Bioavailability of N-acylethanolamines: an Ileostomy Study (NAE Study) (NAE)

Healthy Nutrition

United Kingdom
Moi University
Amsterdam UMC, location VUmc; Princess Maxima Center for Pediatric Oncology

Recruiting

CHildren Treated With Vincristine: A Trial Regarding Pharmacokinetics, DNA And Toxicity of Targeted Therapy In Pediatric Oncology Patients. (CHAPATI)

Pediatric Cancer

Kenya
GlaxoSmithKline

Recruiting

A Study to Evaluate Efficacy and Safety of GSK3858279 in Diabetic Peripheral Neuropathic Pain (NEPTUNE-17)

Pain

United States, Germany, Japan, Spain, Canada, China, United Kingdom, South Africa, Korea, Republic of, France, Poland, Turkey
Aligos Therapeutics

Recruiting

A Study in Healthy Volunteers to Evaluate the Safety, Tolerability, Pharmacokinetics, and Drug-Drug Interaction Potential of Single and Multiple Doses of ALG-097558

COVID-19

United Kingdom
University of Liverpool
Infectious Diseases Institute, Makerere University College of Health Sciences

Recruiting

Pharmacokinetics of Drugs Used to Treat Drug Sensitive Tuberculosis in Breastfeeding Mother-infant Pairs (MILK TB)

Tuberculosis | Breastfeeding | Tuberculosis Active

Uganda
GlaxoSmithKline

Recruiting

A Dose-Finding Study to Evaluate the Efficacy and Safety of GSK3858279 in Adults With Knee Osteoarthritis Pain (MARS-17)

Pain

France, Japan, Spain, China, Korea, Republic of, United States, Argentina, Canada, Germany, South Africa, Australia, Mexico, United Kingdom
Semmelweis University

Recruiting

Hydrocortisone Therapy Optimization During Hypothermia Treatment in Asphyxiated Neonates (UniCort)

Hypotension | Asphyxia | Hypoxic-Ischemic Encephalopathy | Circulatory Failure Neonatal

Hungary
Hoffmann-La Roche

Recruiting

A First-in-Human Study to Investigate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of RO7507062 in Participants With Systemic Lupus Erythematosus

Systemic Lupus Erythematosus

United Kingdom, Spain, Germany, Poland, South Africa, Netherlands
Changchun BCHT Biotechnology Co.
The First Affiliated Hospital of Yunnan University of Traditional Chinese... and other collaborators

Not yet recruiting

Safety, Pharmacokinetics, and Pharmacodynamic Testing of Rabies mAb CBB 1

Rabies Virus Infection

China
Shanghai Zhimeng Biopharma, Inc.

Not yet recruiting

A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of CB06-036 in Subjects With Chronic Hepatitis B

Chronic Hepatitis b
Jiangsu Simcere Pharmaceutical Co., Ltd.

Recruiting

Safety and Pharmacokinetics of SIM0417 Combined With Ritonavir in Healthy Elderly Subjects

Elder

China
Shanghai Pulmonary Hospital, Shanghai, China
Karolinska Institutet; Fudan University; University of Sydney; Shanghai Municipal...

Recruiting

Drug Exposure and Minimum Inhibitory Concentration in the Treatment of MAC Lung Disease

Gram-Positive Bacterial Infections | Mycobacterium Infections | Mycobacterium Avium-Intracellulare Infection | Mycobacterium Avium Complex

China
Qilu Pharmaceutical Co., Ltd.

Recruiting

A Study Evaluates the Safety, Pharmacokinetics, Immunogenicity and Efficacy of QLS31903 in Advanced Solid Tumor Patients

Advanced Solid Tumors

China
Vico Therapeutics B. V.

Recruiting

A Safety and Pharmacokinetics Trial of VO659 in SCA1, SCA3 and HD

Huntington Disease | Spinocerebellar Ataxia Type 3 | Spinocerebellar Ataxia Type 1

Israel, Germany, United Kingdom, Poland, Denmark, Netherlands, France
Bill & Melinda Gates Medical Research Institute
Merck Sharp & Dohme LLC

Recruiting

Safety, Tolerability, Pharmacokinetics (PK), and Food Effect of MK-7762 in Healthy Adults

Tuberculosis

United States
Groupe Hospitalier Pitie-Salpetriere

Recruiting

Pharmacokinetics Study Of Rivaroxaban and Apixaban in Cancer Patients (EPRAPAC)

Anticoagulants and Thrombotic Disorders

France
Bial R&D Investments, S.A.

Recruiting

Efficacy, Safety, Tolerability, Pharmacodynamics, and Pharmacokinetics of BIA 28-6156 in GBA-PD (ACTIVATE)

Parkinson's Disease

United States, Spain, France, Italy, Netherlands, United Kingdom, Germany, Canada, Poland, Portugal, Sweden
Dong-A ST Co., Ltd.

Recruiting

A Study to Evaluate the Effects of Renal Function on Pharmacokinetics and Safety of DA-8010

Healthy | Renal Impairment

Korea, Republic of
Fujian Shengdi Pharmaceutical Co., Ltd.

Recruiting

Clinical Study to Evaluate the Safety, Tolerance and Pharmacokinetic Characteristics of Single Administration of HRS-5635 Injection in Chinese Healthy Subjects and the Safety, Tolerance, Pharmacokinetics and Antiviral Effect of Multiple Administration in Patients With Chronic Hepatitis B

Chronic Hepatitis B

China
Michael Hoelscher
Radboud University Medical Center; University College, London; University of...

Recruiting

PanACEA - STEP2C -01

Pulmonary Tuberculosis | Other Specified Pulmonary Tuberculosis

Gabon, South Africa, Tanzania, Malawi, Uganda, Mozambique
Shen Ning

Recruiting

A Pharmacokinetics Study of Meropenem and Piperacillin in Patients With Sepsis (APSOMAPIPWS)

Sepsis | Acute Kidney Injury

China
Hoffmann-La Roche

Recruiting

A Study to Investigate the Pharmacokinetics and Safety of Risdiplam in Infants With Spinal Muscular Atrophy (PUPFISH)

Muscular Atrophy, Spinal

Germany, United States, Belgium, Italy

Search clinical trials for: Bioavailability, Pharmacokinetics

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