Search clinical trials for: Cholesterol metabolism

Total 29410 results

TRPHARM
Klinar CRO; Düzen Laboratories Group

Terminated

An Observational Study for Evaluation of for the Prevalence of Cerebrotendinous Xanthomatosis (CTX) Disease (GEN-EYE-II)

CTX - Cerebrotendinous Xanthomatosis

Turkey
Wuhan Union Hospital, China

Enrolling by invitation

An Experimental Study on the Effect of Tenofovir Amibufenamide on Blood Lipid During Anti-HBV Treatment

Hepatitis B, Chronic | Lipid Disorder

China
United Arab Emirates University
Mohammed Bin Rashid University of Medicine and Health Sciences

Completed

Effects of a Workplace Exercise Intervention on Cardio-Metabolic Health

Cardiovascular Risk Factor | Pre Diabetes | High Blood Pressure | Elevated LDL Cholesterol

United Arab Emirates
Massachusetts General Hospital
Carol Cosenza, Center for Survey Research at University of Massachusetts,...

Completed

Online Trial Examining Validity and Reliability of the Shared Decision Making Process Survey

Breast Cancer | Colorectal Cancer | Prostate Cancer | High Blood Pressure | High Cholesterol

United States
Orient Pharma Co., Ltd.

Completed

Compare the Efficacy and Safety of 1PC111 With Pitavastatin and Ezetimibe in Patients With Primary Hypercholesterolemia or Mixed Dyslipidemia

Primary Hypercholesterolemia | Mixed Dyslipidemias

Taiwan, Australia, New Zealand
HK inno.N Corporation

Completed

Evaluate Efficacy and Safety of Ezetimibe/Rosuvastatin and Candesartan Cilexetil/Amlodipine Besylate Combination Tablets (REVERT-K)

Hypertension, Hyperlipidemia

Korea, Republic of
Amarin Pharma Inc.

Completed

Efficacy and Safety of AMR101 (Ethyl Icosapentate) in Patients With Fasting Triglyceride (Tg) Levels ≥ 500 and ≤ 2000 mg/dL (MARINE)

Hypertriglyceridemia

United States, Netherlands, Russian Federation, Ukraine, Denmark, Finland, Germany, India, Italy, Mexico, South Africa
Amarin Pharma Inc.

Completed

Effect of AMR101 (Ethyl Icosapentate) on Triglyceride (Tg) Levels in Patients on Statins With High Tg Levels (≥ 200 and < 500 mg/dL) (ANCHOR)

Hypertriglyceridemia

United States
Amarin Pharma Inc.

Completed

A Study of AMR101 to Evaluate Its Ability to Reduce Cardiovascular Events in High-Risk Patients With Hypertriglyceridemia and on Statin (REDUCE-IT)

Cardiovascular Diseases

United States, Australia, Canada, India, Netherlands, New Zealand, Poland, Romania, Russian Federation, South Africa, Ukraine
Sanofi

Completed

Evaluation of the Fixed-dose Combination of Irbesartan/Atorvastatin in Type 2 Diabetic Patients Diagnosed With Hyperlipidemia and Hypertension

Type 2 Diabetes Mellitus

Korea, Republic of
JW Pharmaceutical

Completed

Efficacy and Safety Study of Pitavastatin Versus Atorvastatin to Treat Hypercholesterolemia (PITCH)

Hypercholesterolemia
Population Health Research Institute

Completed

Effects of Acute, Rapid Lowering of LDL Cholesterol With Alirocumab in Patients With STEMI Undergoing Primary PCI (EPIC STEMI)

ST Elevation Myocardial Infarction | Dyslipidemias | Hypercholesterolemia | Hyperlipidemias | Acute Coronary Syndrome | Physiological Effects of Drugs

Canada
Mahidol University
National Research Council of Thailand

Completed

Egg Yolk and Underlying Metabolisms on Modifying HDL Levels in Individuals With Metabolic Syndrome

Metabolic Syndrome

Thailand
All India Institute of Medical Sciences, Bhubaneswar
Coconut Development Board, Government of India

Completed

Effect of Virgin Coconut Oil (VCO) on Cardiometabolic Parameters in Patients With Dyslipidemia

Dyslipidemias

India
Helwan University

Completed

Statins in Patients With Type 2 Diabetes Mellitus and Previous History of Acute Coronary Syndrome

Diabetes Mellitus | Hydroxymethylglutaryl-CoA Reductase Inhibitors

Egypt
Sanofi
Regeneron Pharmaceuticals

Completed

Safety, Tolerability, and Effect of Alirocumab in High Cardiovascular Risk Patients With Severe Hypercholesterolemia Not Adequately Controlled With Conventional Lipid-modifying Therapies (ODYSSEY APPRISE)

Hypercholesterolemia

France, Belgium, Austria, Canada, Czechia, Denmark, Finland, Germany, Greece, Hungary, Poland, Romania, Slovakia, Slovenia, Spain, Switzerland
BIO-CAT Inc.
Atlantia Food Clinical Trials; Cork University Hospital

Completed

Effect of Candida Rugosa Lipase on Serum Triglyceride Lowering

Hypertriglyceridemia

Ireland
Swisse Wellness Pty Ltd
Commonwealth Scientific & Industrial Research Organisation; BIONAP SRL

Completed

Investigating Effects of a Novel Nutraceutical on Hypercholesterolaemia in Australian Adults (CLoNE)

Hypercholesterolemia

Australia
Ukrainian Medical Stomatological Academy

Completed

Effect of Pioglitazone on Insulin Resistance, Atherosclerosis Progression and Clinical Course of Coronary Heart Disease (EFFORT)

Adverse Effect | Atherosclerosis, Coronary | Insulin Resistance Syndrome

Ukraine
Laboratorios Silanes S.A. de C.V.

Completed

Study to Evaluate the Safety of the Fixed-dose Combination Rosuvastatin/Ezetimibe for Patients With Dyslipidaemia (TREZETE)

Dyslipidemias

Mexico
Aswan University Hospital

Completed

Correlation of Serum Adropin to Testosterone and Adiponectin in Obese Men

Obesity | Dyslipidemias

Egypt
UnitedHealth Group

Completed

Transform Type 2: Examining Meal-Delivery and Education for Diabetes Self-Care

Diabetes Mellitus, Type 2 | PreDiabetes

United States
Organon and Co

Completed

Vytorin As Strategy To Reduce Dislipidemia In Adults (0653A-148)

Hyperlipidemia
Organon and Co

Withdrawn

A Study to Evaluate the Efficacy and Safety of Vytorin Versus Standard Treatment of Other Statins in Moderate, Moderately High and High Risk Participants (MK-0653A-406) (VYCTORY)

Dyslipidemia
Organon and Co

Terminated

Investigational Drug in Patients With Hypercholesterolemia or in Patients With Sitosterolemia (0653-026)(COMPLETED)

Lipid Metabolism, Inborn Errors | Hypercholesterolemia, Familial
Brigham and Women's Hospital
Patient-Centered Outcomes Research Institute; McGill University; VA Boston Healthcare...

Active, not recruiting

Comparative Effectiveness and Safety of Four Second Line Pharmacological Strategies in Type 2 Diabetes Study (CER-4-T2D)

Type2 Diabetes | Renal Disease | Cardiovascular Events

United States
Organon and Co

Completed

TWICE (Ezetimibe Together With Any Statin Cholesterol Enhancement)(0653-060)

Hypercholesterolaemia | Hyperlipidaemia
Organon and Co

Completed

Effect Of Ezetimibe Coadministration With Simvastatin In A Middle Eastern Population: A Prospective, Multicentre, Randomized, Double-Blind, Placebo-Controlled Trial (0653-151)

Hypercholesterolemia
Organon and Co

Completed

Open Label Study Evaluating The Use Of Combination Therapy Of Ezetimibe And Statins In Patients With Dyslipidemia In Colombia (0653-141)(COMPLETED)

Lipid Metabolism Disorder
Organon and Co

Completed

Randomized Parallel Group Trial Of The Efficacy And Safety Of Ezetimibe With A Statin Versus Statin Dose Doubling In Patients With Persistent Primary Hypercholesterolemia (0653-152)(COMPLETED)

Hypercholesterolemia
Organon and Co

Completed

Eze/Simva Switch Study in Diabetics (0653A-807)

Diabetes Mellitus, Type 2
Organon and Co

Completed

Comparing an Investigational Medication Versus an Approved Medication in Reducing Cholesterol Levels (0653-025)

Hypercholesterolemia
Organon and Co

Terminated

Vytorin Treating Uncontrolled Lipids (VyTUL) Study (0653A-122)

Cardiovascular Diseases | Diabetes Mellitus
Organon and Co

Completed

Study Evaluating the Efficacy and Safety of Simvastatin Alone Compared With Simvastatin Plus Ezetimibe in Type 2 Diabetic Patients (0653-021)(COMPLETED)

Diabetes Mellitus, Type 2
Organon and Co
Merck Sharp & Dohme LLC

Completed

Ezetimibe Plus Simvastatin Versus Simvastatin Alone in African-American Subjects With Primary Hypercholesterolemia (P03377)

Atherosclerosis | Hypercholesterolemia
Organon and Co
Merck Sharp & Dohme LLC

Completed

Ezetimibe Plus Atorvastatin Versus Atorvastatin Alone in Subjects With Primary Hypercholesterolemia (Study P03406)

Atherosclerosis | Hypercholesterolemia
Organon and Co
Merck Frosst Canada Ltd.

Terminated

Ezetimibe Plus Simvastatin Versus Simvastatin in Patients With Hypercholesterolemia and Coronary Risk Factors (P03405)

Atherosclerosis | Hypercholesterolemia
Organon and Co

Completed

A Long-term Safety and Tolerability Study of Ezetimibe Plus Atorvastatin in Participants With Coronary Heart Disease, Multiple Risk Factors, or Hypercholesterolemia Not Controlled by Atorvastatin (P01418/MK-0653-032)

Hypercholesterolemia
Organon and Co

Completed

Safety and Tolerability Study of Ezetimibe (SCH 058235/MK-0653) Plus Atorvastatin or Simvastatin in Homozygous Familial Hypercholesterolemia (P01417/MK-0653-019)

Hypercholesterolemia
Organon and Co
Merck Sharp & Dohme LLC

Completed

Ezetimibe Plus Atorvastatin Versus Atorvastatin in Untreated Subjects With High Cholesterol (P03434)

Atherosclerosis | Hypercholesterolemia
Organon and Co
Merck Sharp & Dohme LLC

Completed

Assessment of Potential Interaction Between Ezetimibe and Rosuvastatin in Healthy Subjects With High Cholesterol (P03317)

Atherosclerosis | Hypercholesterolemia
Organon and Co
Merck Sharp & Dohme LLC

Completed

Ezetimibe Plus Atorvastatin Versus Atorvastatin in Untreated Subjects With Primary Hypercholesterolemia and Coronary Heart Disease (P03396)

Coronary Artery Disease | Atherosclerosis | Hypercholesterolemia
Organon and Co
Merck Sharp & Dohme LLC

Completed

Ezetimibe Plus Simvastatin Versus Simvastatin in Untreated Subjects With High Cholesterol (P03435)

Atherosclerosis | Hypercholesterolaemia
Organon and Co

Completed

To Evaluate the Lipid-Lowering Efficacy and Safety of Simvastatin 40 Mg Tablet In Patients With Hypercholesterolemia (0733-264)

Hypercholesterolemia

Taiwan
Organon and Co
Merck Sharp & Dohme LLC

Terminated

Effect of Ezetimibe Plus Simvastatin on Flow-Mediated Brachial Artery Vasoactivity in Subjects With Primary Hypercholesterolemia (Study P03336)

Atherosclerosis | Hypercholesterolemia
Organon and Co
Merck Sharp & Dohme LLC

Completed

Effect of Ezetimibe Plus Simvastatin Versus Simvastatin Alone on Atherosclerosis in the Carotid Artery (ENHANCE)(P02578) (ENHANCE)

Atherosclerosis | Hypercholesterolemia | Hyperlipoproteinemia Type II
Organon and Co

Completed

Sitosterolemia Extension Study (0653-004)(COMPLETED)

Heart Disease | Lipid Metabolism, Inborn Errors
Organon and Co

Completed

Effectiveness and Safety of Ezetimibe Added to Atorvastatin in Patients With High Cholesterol and Coronary Heart Disease (Study P03740)

Hypercholesterolemia | Coronary Heart Disease
Organon and Co

Completed

A Study to Evaluate Ezetimibe in Korean Patients With Primary Hypercholesterolemia (0653-042)

Hypercholerolemia
Organon and Co
Bayer

Completed

A 52-week Post-marketing, Observational Study to Confirm the Safety and Efficacy of Zetia Alone or in Combination With Other Lipid-lowering Drugs in Japanese Subjects With Hypercholesterolemia (Study P05245)

Hypercholesterolemia | Familial Hypercholesterolemia | Homozygous Sitosterolemia

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