Search clinical trials for: Controlled human infection model

Total 84805 results

Medical University of Vienna

Completed

Anti-Inflammatory Effect of Statins in the Human Endotoxin Model

Endotoxemia

Austria
Ministry of Health, Israel

Unknown

A Randomized, Controlled, Unblinded, Clinical Trial of the Acceptability and Efficacy of Non-Pharmaceutical Methods in Preventing Spread of Influenza Within the Family

Influenza
Maulana Azad Medical College

Completed

A Randomized Controlled Trial of Lamivudine in Acute Hepatitis B

Hepatitis B

India
Centers for Disease Control and Prevention
Colorado Department of Public Health and Environment; San Francisco Department... and other collaborators

Completed

Project RESPECT: The Efficacy of HIV/STD Prevention Counseling

Sexually Transmitted Diseases | HIV
Amgen

Completed

A Randomized, Controlled, Multicenter Trial of Filgrastim (Recombinant-Methionyl Human Granulocyte Colony Stimulating Factor; G-CSF) for the Prevention of Grade 4 Neutropenia in Patients With HIV Infection.

HIV Infections | Cytopenias

United States, Canada
National Center for Research Resources (NCRR)
Northwestern University

Completed

Randomized Placebo-Controlled Study of Aerobic Exercise and Resistance Training Plus Megestrol Acetate for HIV-Wasting

HIV Infections | Acquired Immunodeficiency Syndrome | HIV Wasting Syndrome
Interferon Sciences

Completed

Double-Blind, Randomized, Placebo-Controlled Study of Low Dose Oral Interferon Alfa-n3 (Human Leukocyte Derived) in ARC Patients

HIV Infections

United States
National Center for Research Resources (NCRR)
National Institute of Allergy and Infectious Diseases (NIAID); Rockefeller...

Completed

Phase II Placebo Controlled Study of Thalidomide in Patients With Mycobacterial and HIV Infections

HIV Infections | Mycobacterium Infections | Tuberculosis
Peking University People's Hospital

Recruiting

Effects of Chinese Medicine and Lactobacillus in Persistent HPV Infection (ELIMVLHPV)

Human Papilloma Virus Infection

China
BioNTech SE

Not yet recruiting

A First-in-human Safety Trial of BNT331 Administered as Single Ascending Doses in Healthy Women and as Multiple Ascending Doses in Women Diagnosed With Bacterial Vaginosis

Bacterial Vaginosis

United States
First Affiliated Hospital of Xinjiang Medical University

Not yet recruiting

Efficacy of Local Antibiotic Injection Via a Catheter for Treating Acute Periprosthetic Infections After Knee DAIR Surgery (YES)

Local Antibiotic Injection Catheter Acute Periprosthetic Infections Knee DAIR Randomized Controlled Trial
AstraZeneca

Not yet recruiting

A Study to Evaluate the Safety, Tolerability and Pharmacokinetics of AZD5148 in Healthy Adults

Healthy Participants

United States
Shanghai Bovax Biotechnology Co., Ltd.

Not yet recruiting

A Phase III Study to Evaluate the Efficacy, Immunogenicity and Safety of the 9-valent HPV Vaccine in Chinese Males

Anal Cancer | HPV-Related Carcinoma | Penile Cancer | Genital Wart | AIN3 | AIN2 | PIN-1 | AIN1 | PIN2 | PIN3

China
Asociación Colombiana de Hepatología

Recruiting

Screening for Hepatitis c in People Who Inject Drugs in Armenia-Colombia (HCV-PIWD)

Hepatitis C Virus Infection

Colombia
InventVacc Biologicals Inc.
Hia Consortium

Recruiting

A Study to Evaluate Safety and Immunogenicity of Haemophilus Influenzae Serotype A Vaccine

Haemophilus Influenzae Meningitis | Invasive Haemophilus Influenzae Disease

Canada
Chinese University of Hong Kong

Not yet recruiting

Stepped Care Treatment for Common Mental Disorders Among Foreign Domestic Helpers

Depression, Anxiety
Canadian Blood Services

Not yet recruiting

Surveillance of Emerging Pathogens to Ensure Blood Supply Safety

Babesioses, Human
Institute of Medical Biology, Chinese Academy of...

Not yet recruiting

Phase IV Study of Concomitant Administration of the sIPV and HepA

Hepatitis A | Polio

China
Sumitomo Pharma Co., Ltd.

Not yet recruiting

First-in-human Study to Assess the Safety, Tolerability and Immunogenicity of the Adjuvanted Universal Influenza Vaccine fH1/DSP-0546LP

Influenza

Belgium
Beijing 302 Hospital

Recruiting

Sequential Combination Therapy With PD-1 Antibody and Peg-IFNα in CHB Patients

Chronic Hepatitis B

China
University Hospital Ostrava

Recruiting

Molecular Characteristics and Prevalence of Viral Hepatitis E in Human Tissue and Cell Donors

Hepatitis E

Czechia
Youssef Khalifa Fakher Botros

Not yet recruiting

Risk Factors and Frequency of Acute Idiopathic Hepatitis in Children at Assiut Children Hospital

Risk Factors and Frequency of Acute Idiopathic Hepatitis in Children at Assiut Children Hospital
Fujian Cancer Hospital
Zhangzhou Municipal Hospital of Fujian Province

Recruiting

Efficacy and Safety of AK104 Combined With Chemotherapy and Recombinant Human Adenovirus 5 Injection in Cervical Cancer

Cervical Cancer Recurrent

China
Shanghai Bovax Biotechnology Co., Ltd.

Not yet recruiting

A Phase I Clinical Trial to Evaluate the Safety of 15-valent HPV Vaccine in Healthy Chinese People Aged 18-45 Years

HPV Infection | HPV-Related Carcinoma | Genital Wart | HPV-Related Intraepithelial Neoplasia

China
Amsterdam UMC
ZonMw: The Netherlands Organisation for Health Research and Development

Not yet recruiting

Preeclampsia Intervention Netherlands (PI-NL)

Pre-Eclampsia | HELLP Syndrome | Pre-eclampsia or Eclampsia With Pre-existing Hypertension | HELLP | Pre-Eclampsia; Complicating Pregnancy | Pre-Eclampsia Onset Less Than 37 Weeks | Pre-Eclampsia as Antepartum Condition | Pre-Eclampsia; Affecting Fetus | HELLP Syndrome Complicating Pregnancy
University of Aarhus
Aarhus University Hospital; University of Copenhagen; Gødstrup Hospital; Statens... and other collaborators

Not yet recruiting

The BEGIN Study Bifidobacterium Infantis to Newborns: Effects of Modulating the Gut Microbial Composition on Growth, Immune Function and Inflammatory Conditions - a Randomized Placebo-controlled Double-blinded Intervention Trial (BEGIN)

Healthy | Healthy Nutrition
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.

Not yet recruiting

A Clinical Study to Evaluate the Efficacy of TQA3038 Injection in Patients With Chronic Hepatitis B

Hepatitis B, Chronic

China
National Taiwan University Hospital

Recruiting

Influenza Vaccine Effectiveness in Among Young Children in Taiwan

Influenza Vaccine Allergy

Taiwan
University of Hamburg-Eppendorf

Not yet recruiting

Model-informed Precision Dosing for Linezolid (LINEMAP)

Gram-Positive Bacterial Infections
Westat
National Institute on Drug Abuse (NIDA); Eunice Kennedy Shriver National Institute... and other collaborators

Not yet recruiting

Behavioral Activation and Risk Reduction for Stimulant Use Among Sexually Active Young Gay/Bisexual Minority Men (IMPACT) (IMPACT)

HIV

United States
Assistance Publique - Hôpitaux de Paris

Not yet recruiting

Predictive Determinants of Nephrotic Syndrome Remission in Patients With At-risk Polymorphism of APOL1 (NEPHROL1)

Focal Segmental Glomerulosclerosis | Nephrotic Syndrome | APOL1 Associated Kidney Disease

France
National Institute of Allergy and Infectious Diseases...
KBio Inc

Not yet recruiting

Phase 1, Randomized, Double-Blind, Placebo-controlled Study to Evaluate the Safety and Tolerability of an Enterovirus D68-specific Monoclonal Antibody in Healthy Adults

Enterovirus Infection

United States
Shandong University

Not yet recruiting

A Multicenter Randomized Controlled Study on the Treatment of Refractory CTIT With Romiplostim N01 Compared to Recombinant Human Thrombopoietin

CTIT-Chemotherapy Induced Thrombocytopenia
Indonesia University
Oxford University Clinical Research Unit

Recruiting

Public Perception and Policy for SARS-CoV-2 Whole Genome Sequencing and Genomics for All

Knowledge, Attitudes, Practice

Indonesia
Changzhi Medical College

Not yet recruiting

Effectiveness of Stress Self-management Health Education Based on IMB Theory Among Nursing Students (IMB)

Psychological Stress | Nursing Students
Jared Fridley

Not yet recruiting

Impact of Prophylactic Use of Irrisept Irrigation System for Spinal Instrumentation

Surgical Site Infection | Spine Surgery | Post-Op Complication | Site Infection | Spinal Instrumentation | Index Spinal Instrumentation | Layer-by-Layer Closure | Locoregional Flap-Based Closure

United States
Pfizer

Recruiting

A Study About Modified RNA Vaccines Against Influenza in Healthy Adults

Influenza, Human

United States
Massachusetts General Hospital
National Cancer Institute (NCI); Fred Hutchinson Cancer Center; University of... and other collaborators

Not yet recruiting

Efficacy of Human Papillomavirus (HPV) Vaccination to Prevent Infection Among Women Living With HIV. (HOPE II)

Hiv | Human Papilloma Virus
Istituto Clinico Humanitas

Not yet recruiting

Efficacy, Safety and Recurrence After Cold-EMR Plus APC for Large Colonic Lesions (EMR+APC)

Colonic Disease

Italy
Institute of Health Information and Statistics...
Institute for Clinical and Experimental Medicine; Brno University Hospital; University... and other collaborators

Recruiting

Early Detection of HCV in Injection Drug Users (EDVIP)

Hepatitis C Virus Infection

Czechia
Hookipa Biotech GmbH

Not yet recruiting

Safety, Reactogenicity and Immunogenicity of HB-502 and HB-501 Versus Placebo in People With HIV on Suppressive ART

Human Immunodeficiency Virus (HIV) Infection

United States
GlaxoSmithKline

Recruiting

A Study to Find the Dose and Assess the Immune Response and Safety of a Vaccine Against Influenza in Healthy Younger and Older Adults

Influenza, Human

United States
Atara Biotherapeutics

Not yet recruiting

A Study to Evaluate the Safety and Preliminary Efficacy of ATA3219 in Participants With Lupus Nephritis

Systemic Lupus Erythematosus | Lupus Nephritis
Fujian Shengdi Pharmaceutical Co., Ltd.

Not yet recruiting

A Multicenter, Randomized, Open, Parallel-designed Study to Evaluate the Efficacy and Safety of HRS-5635 Injection Alone or in Combination With Other Agents in Patients Treated for Chronic Hepatitis B

Chronic Hepatitis B

China
Belgian Research on AIDS and HIV Consortium

Not yet recruiting

Use of Long-Acting Injectable Cabotegravir/Rilpivirine for the Treatment of HIV in Belgium

Human Immunodeficiency Virus
GlaxoSmithKline
PPD; Laboratory Corporation of America

Not yet recruiting

Study to Evaluate the Effect of Bepirovirsen on Cardiac Conduction as Assessed by 12-lead Electrocardiogram in Healthy Volunteers

Hepatitis B

United States
Rockefeller University
Cornell University

Not yet recruiting

Thermogenic Silencer Regulatory Factors in Humans

Obesity | Metabolic Disease | Cold Exposure
Centre Hospitalier Universitaire de Nice

Not yet recruiting

Descriptive Analysis of Changes in Hepatitis B Markers in People Living With HIV on Injectable Therapy.

Hepatitis B | Hiv Infection

France
Fondazione Policlinico Universitario Agostino Gemelli...

Recruiting

Validation of a Preclinical Model Based on Patient-derived Organoids for the Study of the Gut-joint Axis in Spondyloarthritis (ORGANOSPA)

Inflammatory Bowel Diseases | Spondyloarthritis

Italy
Mahidol University

Not yet recruiting

Dengue Vaccine Hesitancy Among International Travelers

Vaccine Hesitancy

Search clinical trials for: Controlled human infection model

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