Search clinical trials for: Double blind

Total 6854 results

Soleno Therapeutics, Inc.

Completed

Open-Label Extension Study of DCCR in PWS Followed by Double-Blind, Placebo-Controlled, Randomized Withdrawal Period

Prader-Willi Syndrome

United States, United Kingdom
UCB Pharma

Completed

A Multi-Centre, Randomized, Double-Blind, Placebo Controlled Pilot Trial to Assess the Efficacy, Safety, and Tolerability of SPM 927 in Subjects With Postherpetic Neuralgia (PHN).

Postherpetic Neuralgia
Dompé Farmaceutici S.p.A

Completed

A Phase 2, Multicentre, Randomized, Double-blind, Placebo-controlled Study in Patients With New-onset Type 1 Diabetes

Diabetes Mellitus, Insulin-Dependent

Germany, Belgium, Italy
AstraZeneca

Completed

A Phase II, Randomized, Double-blind, Placebo-controlled Study to Assess MEDI3506 in Participants With COPD and Chronic Bronchitis (FRONTIER-4)

Chronic Obstructive Pulmonary Disease (COPD) | Chronic Bronchitis

United States, Canada, Denmark, Spain, United Kingdom, Taiwan, New Zealand, Australia, Germany, Israel, South Africa, Czechia, Hungary, Poland, Netherlands
TJ Biopharma Co., Ltd.

Terminated

A Study to Evaluate the Safety, Tolerability, and PK Profile of Single and Multiple Doses TJ202 in Patient With Systemic Lupus Erythematosus

Systemic Lupus Erythematosus (SLE)

China
CytoDyn, Inc.
Amarex Clinical Research

Completed

Double Blind, Placebo Controlled Study of Safety and Efficacy of Leronlimab in Patients With "Long" COVID-19

Coronavirus Disease 2019

United States
Hope Biosciences Stem Cell Research Foundation

Completed

Randomized Double-Blind Phase 2 Study of Allogeneic HB-adMSCs for the Treatment of Chronic Post-COVID-19 Syndrome (HBPCOVID02)

Post COVID-19 Syndrome

United States
National Institute of Allergy and Infectious Diseases...
GlaxoSmithKline; PPD; Rho Federal Systems Division, Inc.; Immune Tolerance Network...

Active, not recruiting

Belimumab With Rituximab for Primary Membranous Nephropathy (REBOOT)

Nephrotic Syndrome | Membranous Nephropathy

United States, Canada
Denovo Biopharma LLC

Completed

A Biomarker-Guided, Randomized, Double-Blind, Placebo-Controlled Efficacy and Safety Study of Liafensine in Patients With Treatment-Resistant Depression (ENLIGHTEN)

Treatment Resistant Depression

United States, Canada
University Hospital, Clermont-Ferrand
Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement and other collaborators

Terminated

GlutN : Randomized, Double-blind, Crossover Clinical Trial to Confirm the Role of Gluten in Non-celiac Gluten Sensitivity (GLUTN)

The Objective is to Confirm the Role of Gluten in Triggering the Digestive and Extradigestive Symptoms of NCGS

France
Precision Life Sciences Group
Medelis Inc.

Suspended

Phase 3 Randomized, Double-blind, Controlled Study of ICT-107 in Glioblastoma

Glioblastoma Multiforme

United States, Canada, Austria
Massachusetts General Hospital
National Institute on Drug Abuse (NIDA)

Active, not recruiting

Varenicline for Nicotine Vaping Cessation in Adolescents (ViVA)

Nicotine Dependence | Vaping

United States
Central South University

Completed

A Double-blind, Placebo-controlled Study of Antidepressant Augmentation With Agomelatine

Major Depressive Disorder

China
University of Manitoba
The Hospital for Sick Children; University of British Columbia; McGill University

Enrolling by invitation

Predictors of Persistent Peanut Allergy at Age 5 Years

Allergy to Peanut
Dan Hasson
AFA Insurance; Stiftelsen Stressmottagningen

Completed

Possible Effects of the Dietary Supplement Magnesium Compared to Placebo

Health Promotion
AstraZeneca

Active, not recruiting

A Comparative Study of AZD9833 Plus Palbociclib Versus Anastrozole Plus Palbociclib in Patients With ER-Positive HER2 Negative Breast Cancer Who Have Not Received Any Systemic Treatment for Advanced Disease (SERENA-4)

ER-Positive HER2-Negative Breast Cancer

Austria, Belgium, France, Germany, Italy, United Kingdom, United States, Canada, India, Taiwan, Russian Federation, Korea, Republic of, Hungary, Japan, Mexico, Turkey, China, Malaysia, Spain, Czechia, Portugal, Poland, Norway, Bulgaria, Slovaki... and more
Kanyos Bio, Inc., a wholly-owned subsidiary of...

Completed

Assessment of KAN-101 in Celiac Disease (ACeD)

Celiac Disease

United States
MYOS Corp
Citruslabs

Completed

A Randomized, Double-Blind, Controlled Trial to Assess the Efficacy of a Fortetropin Supplement in Improving Symptoms of Osteoarthritis

Osteoarthritis

United States
University Hospital, Basel, Switzerland

Withdrawn

Prospective Double-blind Study for the Use of Aspirin During Transurethral Surgery of the Bladder or the Prostate

Blood Loss, Surgical | Intraoperative Complications | Re-operation Rates in Patients With Aspirin Treatment

Switzerland
State University of New York at Buffalo

Terminated

Double Blinded Randomized Control Trial of Types of IVF in Children With DKA

Diabetic Ketoacidosis

United States
MeiraGTx, LLC

Active, not recruiting

A Double-blind Study to Evaluate the Safety of Glutamic Acid Decarboxylase Gene Transfer in Parkinson's Participants

Parkinson Disease

United States
Zhejiang University

Completed

Double-blind and Placebo-controlled Study on Intervention Effect of Medium and Long Chain Fatty Acid Triglyceride on Glycolipid Homeostasis in Patients With Metabolic Syndrome and Mechanisms

Metabolic Syndrome

China
Geistlich Pharma AG

Withdrawn

AMIC vs. MFx in the Ankle (AMARTA)

Chondral Defect | Osteochondral Lesion of Talus | Microfracture

United Kingdom
Rabin Medical Center
NG Solutions Ltd

Active, not recruiting

Double Blind, Randomized, Placebo Controlled Pilot Study to Evaluate the Effect of Nutritional Supplementation on Physical Activity Performance of Young Soccer Players

Growth | Nutritional Supplementation

Israel
AstraZeneca

Completed

Phase III Study to Determine Efficacy of Durvalumab in Stage II-III Non-small Cell Lung Cancer (NSCLC) After Curative Intent Therapy. (MERMAID-2)

Carcinoma, Non- Small Cell Lung

United States, Canada, France, Italy, Netherlands, Spain, Belgium, Poland, Taiwan, Vietnam, Korea, Republic of, Brazil, Czechia, Hungary, Japan, Peru, Russian Federation, Hong Kong, Israel, Greece, Australia, Singapore, Turkey, India, A...
Rivus Pharmaceuticals, Inc.

Active, not recruiting

Exploratory Ph 2A, Double-Blind, Placebo-Controlled Dose Escalation Study of Safety, Tolerability, PD, & PK of HU6 for Subjects With Obese HFpEF (HFpEF)

Heart Failure With Preserved Ejection Fraction

United States
Göteborg University
Sahlgrenska University Hospital, Sweden

Terminated

Iodine Status in Swedish Lactating Women - Effect of Iodine Supplementation in the Thyroid Function of Mother and Infant

Lactation | Thyroid Gland; Node

Sweden
GlaxoSmithKline

Completed

A Study to Evaluate Safety, Tolerability, Pharmacokinetics and Pharmacodynamics (PD) of GSK3888130B in Healthy Participants

Multiple Sclerosis

United Kingdom
Enlivex Therapeutics Ltd.

Terminated

A Phase 2b Multi-Center, Randomized, Double-Blind, Placebo-Controlled Study, Evaluating Efficacy and Safety of Allocetra-OTS in Patients With Severe or Critical COVID-19 With Associated Acute Respiratory Distress Syndrome (ARDS)

Covid19

Israel
Odense University Hospital

Active, not recruiting

The DANish COronary DEcalcification (DANCODE) Trial (DANCODE)

Coronary Artery Disease

Denmark
Albireo

Completed

Double-blind, Randomised Study of A3384 in BAM/BAD

Bile Acid Malabsorption

Sweden, United Kingdom
PepsiCo Global R&D

Completed

A Prospective, Randomized, Placebo-controlled, Double-blind Study to Assess the Efficacy of Bacillus Coagulans Unique IS2 on Improving Bowel Movement Characteristics, Gastrointestinal-related Symptoms and Quality of Life in Healthy Adult Participants

Stool Frequency

Canada
Igy Inc.
Vetanda Group Ltd

Completed

A Randomized, Double-Blind, Placebo Controlled, Crossover Trial to Evaluate Safety and Efficacy of AGY in Celiac Disease (AGY-010)

Celiac Disease

Canada
Infectopharm Arzneimittel GmbH
Gesellschaft für Therapieforschung mbH

Completed

5% KOH Solution vs. Placebo and Diclofenac Gel for the Treatment of Actinic Keratosis (KOHDIAK)

Actinic Keratosis

Germany
Amorphical Ltd.

Terminated

A Single Arm Study Comparing ACC Supplement to CCS in Management of Hypoparathyroidism (AMCS009)

Hypoparathyroidism

Israel
City of Hope Medical Center
National Cancer Institute (NCI)

Active, not recruiting

Chemotherapy Followed by Surgery, Chemotherapy, and Radiation Therapy in Treating Patients With Locally Advanced Head And Neck Cancer

Head and Neck Cancer
Hervé SPECHBACH
OM Pharma SA

Completed

Assessment of the Efficacy of Calcium Dobesilate vs. Placebo on SARS-CoV-2 Viral Load Amongst Outpatients With COVID-19. (COVID-19)

COVID-19 Virus Disease

Switzerland
Amorphical Ltd.

Withdrawn

Investigating the Safety, Tolerability and Efficacy of Amorphous Calcium Carbonate (ACC) on the Treatment of Subjects With CRPC

Castrate Resistant Prostate Cancer With Bone Metastasis

Israel
Amorphical Ltd.

Terminated

Improving Function,Welfare of Late-stage Cancer Subjects by ACC

Solid Malignancies, With or Without Lung Metastases

Israel
Amorphical Ltd.

Terminated

The Effect of Amorphous Calcium Carbonate (ACC) Treatment on Function and Welfare in Late-stage Solid Cancer Subjects (ONCO-004-1)

Oncology

Israel
Hope Biosciences Stem Cell Research Foundation

Active, not recruiting

Randomized Double-Blind Phase 2 Efficacy and Safety of Autologous HB-MSCs vs Placebo for Treatment of Multiple Sclerosis (HBMS01)

Multiple Sclerosis

United States
Masonic Cancer Center, University of Minnesota

Completed

Prevention of Bone Loss After Pediatric Hematopoietic Cell Transplantation

Osteoporosis | Osteopenia

United States
Istanbul Medipol University Hospital

Enrolling by invitation

Retrospective Evaluation of the Results of Direct Pulp Capping Treatment

Pulp Exposure, Dental

Turkey
Larimar Therapeutics, Inc.

Completed

A Double-Blind, Placebo-Controlled, Dose Exploration Study of CTI-1601 in Adult Subjects With Friedreich's Ataxia

Friedreich Ataxia

United States
Hoffmann-La Roche

Terminated

Double-Blinded, Placebo-Controlled Phase 1b Study for Safety, PK, Efficacy, PD of RO7049665 in Participants With Ulcerative Colitis (UC)

Ulcerative Colitis

United States, Hungary, Georgia, Moldova, Republic of, Ukraine
Rigshospitalet, Denmark

Terminated

A Randomized, Double-blinded, Clinical, Placebo-controlled Trial on the Effects of Therapy With Letrozole and hUman Choriongonadotropin in Male Hypogonadism Induced by Illicit Use of Anabolic Androgenic Steroids- The LUCAS Trial

Hypogonadotropic Hypogonadism | Hypogonadism | Hypogonadism, Male

Denmark
Indonesia University

Completed

EFFECTIVENESS AND SAFETY OF CREAM CONTAINING SPENT GRAIN WAX EXTRACT, ARGAN OIL, AND SHEA BUTTER POST-TRICHOLOROACETIC ACID 15% PEEL: RANDOMIZED, CONTROLLED, DOUBLE-BLIND, SPLIT-FACE CLINICAL TRIAL

Aging Disorder

Indonesia
GlaxoSmithKline

Terminated

A Phase III Double-blind Study to Assess Safety and Efficacy of an RSV Maternal Unadjuvanted Vaccine, in Pregnant Women and Infants Born to Vaccinated Mothers (GRACE)

Respiratory Syncytial Virus Infections

United States, Australia, France, Finland, Taiwan, Spain, Philippines, Mexico, Belgium, Italy, Panama, New Zealand, Thailand, Brazil, Canada, India, Colombia, Korea, Republic of, United Kingdom, South Africa, Argentina, Bangladesh, Dominican... and more
Mahidol University

Completed

The Effects of Vitamin D and Calcium Supplementation to Parathyroid Hormone in CHB Patients Treated With TDF (TDF)

Chronic Hepatitis B Virus | Vitamin D | Tenofovir Disoproxil Fumarate | Parathyroid Hormone

Thailand
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Terminated

Combination Chemotherapy and Inotuzumab Ozogamicin in Treating Patients With B Acute Lymphoblastic Leukemia

B Acute Lymphoblastic Leukemia | B Acute Lymphoblastic Leukemia, Philadelphia Chromosome Negative | Acute Lymphoblastic Leukemia in Remission

United States

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