Search clinical trials for: First Time in Humans

Total 458349 results

Eli Lilly and Company

Completed

A Study of Chemotherapy and Ramucirumab Versus Chemotherapy Alone in Second Line Non-Small Cell Lung Cancer (NSCLC) Participants Who Received Prior First Line Platinum-based Chemotherapy

Non-Small Cell Lung Cancer

United States, Germany, Israel, Italy, Mexico, France, Poland, Romania, Spain, Taiwan, United Kingdom, Hungary, Austria, Argentina, Korea, Republic of, Greece, Turkey, India, Netherlands, Russian Federation, Canada, Norway, Sweden, Br... and more
National Center for Complementary and Integrative...

Completed

MEG Study of Mindfulness Based Stress Reduction

Somatosensory Cortical Dynamics in Normal Humans

United States
GlaxoSmithKline

Completed

A Phase 1, First Time in Human (FTIH) Study to Evaluate GSK3352589, a REarranged During Transfection (RET) Growth Factor Receptor Tyrosine Kinase Inhibitor, in Healthy Volunteers

Irritable Bowel Syndrome

Australia
Istanbul University

Completed

Infraclavicular Block Properties in Diabetic Patients

Pain, Postoperative | Diabetes Mellitus | Nerve Block Duration

Turkey
Xijing Hospital of Digestive Diseases
Shanghai Zhongshan Hospital; Tongji Hospital; Peking University Cancer Hospital... and other collaborators

Completed

Efficacy and Safety of Endoscopic Submucosal Tunnel Dissection for Superficial Esophageal Squamous Cell Carcinoma

Esophageal Superficial Mucosal Lesion

China
GlaxoSmithKline

Completed

First Time in Human Study to Assess the Safety, Tolerability and Pharmacokinetics of GSK3389404 in Healthy Subjects

Hepatitis B

United Kingdom
Université de Reims Champagne-Ardenne

Completed

EXercise Training for Reducing Anxiety in First-Time Inmates (EXTRA)

Anxiety State
GlaxoSmithKline

Completed

Dose Escalation Study to Investigate the Safety, Pharmacokinetics, and Pharmacodynamics of GSK2849330 in Subjects With Advanced Her3-Positive Solid Tumors

Neoplasms | Cancer

Australia, United States, Netherlands
Loughborough University
British Heart Foundation

Completed

Kids FIRST: Family-based Intervention to Reduce Snacking and Screen Time in Children

Sedentary Lifestyle | Sedentary Behavior | Diet Habit
AstraZeneca

Completed

AZD9496 First Time in Patients Ascending Dose Study

ER+ HER2- Advanced Breast Cancer

United States, United Kingdom, Korea, Republic of
China Medical University, China

Unknown

S1+ Paclitaxel (IV&IP) + Bevacizumab (IP) Versus S1+Oxaliplatin as First-line Treatment in Gastric Cancer With Malignant Ascites

Metastatic Gastric Adenocarcinoma

China
The First Affiliated Hospital of Zhengzhou University
The First Affiliated Hospital of Henan University of Science and Technology; First Affiliated Hospital of Xinjiang Medical University and other collaborators

Unknown

Prevention of Coronary Slow Flow or No-Reflow During EPCI in Patients With Acute STEMI (NOSLOWFLOW-Ⅱ)

ST Segment Elevation Myocardial Infarction | Elective Percutaneous Coronary Intervention

China
Guangzhou Institute of Respiratory Disease

Unknown

The Diagnostic Yield and Safety of Transbronchial Cryobiopsy in Different Freezing Time in the Diffuse Parenchymal Lung Diseases

Safety | Transbronchial Cryobiopsy | Freezing Time | Diagnostic Yield

China
Wageningen University

Completed

The Fasting Study - Unraveling the Mechanistic Effects of Prolonged Fasting in Humans.

Fasting | Clinical Trial | Lipid Metabolism | Adipose Tissue

Netherlands
GlaxoSmithKline

Completed

First Time in Human (FTIH) Safety and Pharmacokinetics (PK) Study of GSK3036656 in Healthy Subjects

Tuberculosis

United Kingdom
University of Colorado, Denver

Completed

Immobilization in External Rotation After First Time Anterior Shoulder Dislocation

Shoulder Dislocation

United States
Nottingham University Hospitals NHS Trust
Aston University

Completed

Evaluation of Self-management Education in First Time Hearing Aid Users

Hearing Loss
Tychan Pte Ltd.
National University Hospital, Singapore; National University, Singapore; Duke-NUS... and other collaborators

Completed

Safety and Tolerability of an Antibody Against Zika Virus (Tyzivumab) in Humans

Treatment of Acute Zika Virus Infection

Singapore
National Taiwan University Hospital

Unknown

Effects of Prenatal Preparation Education on First-time Parents

Parenting | Partner, Domestic
Luxembourg Institute of Health
DECATHLON SA

Completed

Effects of Shoe Cushioning and Body Mass on Injury Risk in Running (RRI_Interv4)

Running-Related Injury (First-time)

Luxembourg
Guangzhou Institute of Respiratory Disease
First Affiliated Hospital, Sun Yat-Sen University; Nanfang Hospital of Southern... and other collaborators

Unknown

Clinical Trial of Thoracoscopic Bullectomy Surgery Under Spontaneous Ventilating Anesthesia

Complication, Postoperative | Stability During Surgical Operation | Postoperative Hospitalization Time

China
Chang Gung Memorial Hospital

Unknown

Daily Four Times or Two Times Usage of PPI and Amoxicillin for the First or Second Line H. Pylori Eradication

Helicobacter Pylori Infection | Helicobacter Gastritis | Helicobacter-Associated Pyloric Ulcer

Taiwan
Pfizer

Completed

A Clinical Trial to Study the Safety, Tolerance and Immunogenic Response to MCV4, Tdap and Bivalent rLP2086 Vaccine When Given at the Same Time to Children Between the Ages of 10 Through 12 Years of Age

Vaccines | Meningococcal Vaccines

United States
Pfizer

Completed

A Clinical Trial to Study the Safety, Tolerance and Immunogenic Response to Gardasil and Bivalent rLP2086 Vaccine When Given at the Same Time to Children Between the Ages of 11 and 17

Vaccines | Meningococcal Vaccines

United States
Viscofan
Ministerio de Ciencia e Innovación, Spain

Unknown

First in Humans to Evaluate Collagen Patches With Stem Cells in Patients With Ischemic Left Ventricular Dysfunction (CARDIOMESH)

Heart Failure With Reduced Ejection Fraction

Spain
Xijing Hospital

Withdrawn

Effects of Berberine Hydrochloride and Bifidobacterium in Prediabetes Prevention and Treatment

Prediabetes

China
First Hospital of Shijiazhuang City
Peking University People's Hospital; Tianjin Medical University Cancer Institute... and other collaborators

Unknown

Circulating Tumor DNA Longitudinal Monitoring in Stage III-IV Lung Cancer Patients

Carcinoma | Non-small Cell Lung Cancer | Lung Neoplasm

China
University Hospital, Rouen

Unknown

Is the Distance of Patients From Rouen University Hospital Influencing the Time Between Colectomy and First Chemotherapy Cure for Colon Cancer? (DICHIMIO)

Chemotherapy | Colectomy | Cancer Colon

France
Institute of Tropical Medicine, Belgium
SRI International; Sihanouk Hospital Center of HOPE

Completed

Study to Obtain Blood and Voided Urine Samples to Improve the Diagnosis of Melioidosis

Systemic Inflammatory Response Syndrome | Melioidosis | Suspected or Confirmed Bloodstream Infections

Cambodia
University Hospital of Split

Unknown

Proactive Breastfeeding Support in First Time Mothers

Breastfeeding

Croatia
GlaxoSmithKline

Completed

A First Time in Human Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of GSK2798745 in Healthy Subjects and Stable Heart Failure Patients

Oedema, Pulmonary

United Kingdom
Actelion

Completed

Retrospective Chart Review of First-time Opsumit® (Macitentan) Users in the United States (OrPHeUS)

Pulmonary Arterial Hypertension

United States, Puerto Rico
Centre for Addiction and Mental Health
American Academy of Child Adolescent Psychiatry.

Completed

MR Imaging of Fat Deposition in Adolescents With First Time Antipsychotic Use

Adiposity

Canada
Eli Lilly and Company

Completed

A First Human Study of a Ferroportin Antibody

Healthy Volunteers

Singapore
GlaxoSmithKline

Completed

A First Time in Human Study to Investigate the Safety, Tolerability and Pharmacokinetics of Single & Repeat Escalating Doses of GSK2878175 in Healthy Subjects

Hepatitis C, Chronic

Australia
GlaxoSmithKline

Completed

A Phase I/IIa, First Time in Human, Study of GSK2636771 in Subjects With Advanced Solid Tumors With Phosphatase and Tensin Homolog (PTEN) Deficiency

Cancer

Korea, Republic of, United States, United Kingdom
GlaxoSmithKline

Completed

Phase I Study to Assess the Safety, Pharmacokinetics, & Pharmacodynamics of GSK923295 in Subjects w/ Refractory Cancer

Cancer

United States
First Affiliated Hospital of Wenzhou Medical University

Unknown

Intensive Insulin for Severe/Moderate Hypertriglyceridemia Pancreatitis. (HAPinsulin)

Hypertriglyceridemia | Acute Pancreatitis
The First Affiliated Hospital with Nanjing Medical...

Unknown

Day Regimes of CONbercept on CytokinEs of PDR Patients Undergoing Vitrectomy - Trial (CONCEPT) (CONCEPT)

Proliferative Diabetic Retinopathy | VEGF Overexpression

China
Wills Eye
Genentech, Inc.; Novartis Pharmaceuticals

Completed

Lucentis Versus Mitomycin C During Glaucoma Surgery

Glaucoma

United States
Peptinnovate

Completed

A First Time in Human Study of PIN201104 in Healthy Volunteers and Patients With Asthma

Asthma | Healthy Volunteers

United Kingdom
West China Hospital

Unknown

Ultrasonic Scalpel vs. Monopolar Electrocautery for D2 Distal Gastric Carcinoma Surgery (CGCT-01)

Quality of Life | Gastric Cancer | Surgery | Blood Loss, Surgical | External Causes of Morbidity and Mortality | Ultrasonic Scalpel | Monopolar Electrocautery | Operation Time

China
Peking Union Medical College Hospital
The First Affiliated Hospital with Nanjing Medical University; Guangdong Provincial... and other collaborators

Unknown

Intravenous Administration of Insulin and Plasma Exchange on Triglyceride Levels in Early Stage of Hypertriglyceridemia-induced Pancreatitis

Hypertriglyceridemia | Pancreatitis, Acute
GlaxoSmithKline

Completed

Open-label Study to Investigate the Safety, PK, and Pharmacodynamics of GSK1120212 in Subjects With Solid Tumors or Lymphoma

Solid Tumours

United States
GlaxoSmithKline

Completed

A Phase I Study to Investigate the Safety, Pharmacokinetics, and Pharmacodynamics of GSK2118436 in Subjects With Solid Tumors

Cancer

Australia, United States
GlaxoSmithKline

Completed

A Phase I, Open-Label, First-Time-In-Human Study of the Oral AKT Inhibitor GSK2141795

Cancer

United States, Canada
Hanmi Pharmaceutical Company Limited

Completed

A First-in-human Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of HM12460A (HM12460A)

Healthy | Type 2 Diabetes Mellitus | Type 1 Diabetes Mellitus

United States
University of California, Davis
Mars, Inc.

Completed

Absorption, Metabolism and Excretion of Dietary Polyphenolic Bioactives in Humans

Healthy

United States
GlaxoSmithKline

Terminated

GW824575 First Time in Human

Retinal Diseases

United Kingdom
Northern Orthopaedic Division, Denmark
Aalborg University; Association of Danish Physiotherapists; The Danish Rheumatism... and other collaborators

Completed

Structured Treatment of Osteoarthritis of the Knee With or Without Total Knee Replacement (MEDIC)

Osteoarthritis of the Knee

Denmark

Search clinical trials for: First Time in Humans

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Bosnia & Herzegovina

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations