Search clinical trials for: Fragile

Total 434 results

University of California, Davis
National Institute of Mental Health (NIMH)

Completed

Examining Social, Emotional, and Cognitive Functioning in People With Fragile X and Down Syndromes

Anxiety Disorders | Child Developmental Disorders, Pervasive

United States
University of Colorado, Denver
Arcadia University

Completed

Improving Function, Participation and Function After Acute Hospitalization in Older Adults

Frail Older Adults

United States
Indiana University
Indiana Clinical and Translational Sciences Institute

Completed

Riluzole in Fragile X Syndrome

Fragile X Syndrome

United States
Indiana University School of Medicine

Completed

A Prospective Open-label Study of Aripiprazole in Fragile X Syndrome

Fragile X Syndrome

United States
Universitaire Ziekenhuizen KU Leuven
KU Leuven

Completed

Incidence and Risk Factors for Hospitalization-Associated Disability

Iatrogenic Disease | Functional Decline | Hospitalization-associated Disability

Belgium
University of North Carolina, Chapel Hill
Allergan

Completed

Topical Cyclosporine Suspension for the Treatment of Brittle Nails

Brittle Nail Syndrome

United States
University of North Carolina, Chapel Hill
Agency for Healthcare Research and Quality (AHRQ)

Terminated

Educational-Medical-Behavioral Treatment of Fecal Incontinence (FIX)

Fecal Incontinence

United States
Taipei Veterans General Hospital, Taiwan

Completed

Taiwan Health Promotion Intervention Study for Elders (THISCE)

Cognitive Impairment | Frail Elderly Syndrome | Cognitive Decline
Institute for Neurodegenerative Disorders

Completed

A PET Brain Imaging Study of mGluR5 in Subjects With Neuropsychiatric Conditions (FPEB)

Parkinson Disease | Alzheimer Disease | Mild Cognitive Impairment | Fragile X Syndrome | Huntington Disease | Autistic Spectrum Disorders

United States
Hoffmann-La Roche

Completed

A Study To Assess the Quality and Strength of Bone in Women Participants With Osteoporosis Taking Oral Ibandronate Versus Placebo

Osteoporosis

United States
North Western Research Collaborative
Older persons Surgical Outcomes Collaboration

Unknown

Emergency Laparotomy and Frailty Study (ELF)

Emergencies | Laparotomy | Frail Older Adult
Hoffmann-La Roche

Completed

A Study With RO4917523 in Patients With Fragile X Syndrome

Fragile X Syndrome

United States
Hasselt University

Unknown

Inactivity, Balance Problems and Fall Risk in Institutionalized Frail Elderly

Institutional Frail Elderly

Belgium
The Hong Kong Polytechnic University
Pentecostal Church of Hong Kong

Completed

Healthy Living Programme for Older Adults (HLP)

Frail Older Adults
Indonesia University

Unknown

Effects of Metformin in Pre-frail Elderly

Pre-frail Elderly

Indonesia
CHU de Quebec-Universite Laval
Ministere de la Sante et des Services Sociaux; TVN 2013 Core Research Grant... and other collaborators

Completed

Improving Decision Making On Location of Care With the Frail Elderly and Their Caregivers (DOLCE)

Decision Process About the Location of Care Among Frail Elderly

Canada
Assistance Publique Hopitaux De Marseille

Unknown

Preventive Fixation of Lower Limbs in Osteogenesis Imperfecta (Brittle Bone Disease) With the Highlight of the Fassier-Duval (Fassier-Duval)

Brittle Bone Disease

France
Hoffmann-La Roche

Completed

A Study of RO4917523 in Pediatric Patients With Fragile X Syndrome

Fragile X Syndrome

United States
Florida Atlantic University
Advanced Diabetes Treatment Centers

Terminated

Effects of Pulsatile Intravenous Insulin Therapy on Metabolic Integrity in Patients With Diabetes Mellitus

Diabetes Mellitus, With Complications

United States
CHU de Reims

Completed

Frail Elderly Subjects - Evaluation and Follow-Up (SAFES Cohort)

Frail Elderly People

France
Alliance for Clinical Trials in Oncology
National Cancer Institute (NCI)

Completed

Vinorelbine in Treating Older Patients With Stage IIIB or Stage IV Non-small Cell Lung Cancer

Lung Cancer

United States
Hoffmann-La Roche

Completed

A Study of RO4917523 in Patients With Fragile X Syndrome

Fragile X Syndrome

France, Spain, United States, Peru, Canada, United Kingdom, Chile, Argentina, Mexico, Sweden
PH Research, S.L.

Completed

Nab-paclitaxel in Combination With Gemcitabine in Fragile Patients With Advanced Pancreatic Cancer (FRAGANCE)

Advanced Pancreatic Cancer

Spain
Alcobra Ltd.

Completed

A 6-week, Study of MG01CI Low Dose and High Dose Compared With Placebo in Adults and Adolescents With Fragile X Syndrome

Fragile X Syndrome

United States, Israel
Indonesia University

Unknown

The Effect of SOD Enzyme on Frailty and HRQOL Among Indonesian Pre-frail Elderly: A Double Blind Randomized Controlled Trial

Pre-frail Elderly

Indonesia
Novartis Pharmaceuticals

Terminated

Long-term, Safety, Tolerability and Efficacy Study of AFQ056 in Adult Patients With Fragile X Syndrome

Fragile X Syndrome

Germany, United States, Switzerland, Australia, Canada, Denmark, France, Italy, United Kingdom, Spain
San Francisco Veterans Affairs Medical Center

Unknown

The Effects of Frailty on Chronic Kidney Disease

Chronic Kidney Disease | Sarcopenia

United States
King's College Hospital NHS Trust

Unknown

Does Frailty Help Predict Postoperative Outcomes in Cardiac Surgery? (FOCuS)

Heart Valve Diseases | Coronary Heart Disease
University of North Carolina, Chapel Hill

Completed

Brain Connectivity in Neurodevelopmental Disorders in Response to Treatment

Fragile X Syndrome | Psychosis | Autism Spectrum Disorders

United States
Novartis Pharmaceuticals

Terminated

Long-term, Safety and Tolerability Study of AFQ056 in Adolescent Patients With Fragile X Syndrome (Open-label)

Fragile X Syndrome

United States, Belgium, Australia, Israel, Switzerland, Germany, Denmark, Italy, Netherlands, Spain, Sweden, United Kingdom, France
Stanford University
National Institute of Mental Health (NIMH); Autism Speaks

Completed

Randomized Controlled Study of Donepezil in Fragile X Syndrome

Fragile X Syndrome

United States
Tianjin Medical University General Hospital

Completed

Rocuronium Consumption in Etomidate-based and Propofol-based General Anesthesia Under Sevoflurane

Neuromuscular Monitoring
Novartis Pharmaceuticals

Terminated

EXPLAIN -FragilE X Registry: An exPlorative Longitudinal Study for chAracterIzation, Treatment Pathways and patieNt-related Outcomes (EXPLAIN)

Fragile-X Syndrome

Germany
FRAXA Research Foundation
Fragile X Research Foundation of Canada

Completed

Add-on Pilot Trial of Minocycline to Treat Fragile X Syndrome

Fragile X Syndrome

Canada
German Breast Group

Completed

Adjuvant Chemotherapy for Elderly Non Frail Patients With an Increased Risk for Relapse of a Primary Carcinoma of the Breast (ICE-II)

Breast Cancer

Germany
Université Catholique de Louvain

Completed

Frailty and Postoperative Shock

Frailty | Elderly
Wageningen University
DSM Nutritional Products, Inc.; Top Institute Food and Nutrition

Completed

The Effect of Calcifediol (Hy.D 25 SD/S) and Vitamin D3 on Muscle Strength in a Frail Elderly Population (D-Fit)

Elderly, Frail | Deficiency, Vitamin D

Netherlands
Regione Veneto
European Commission; Local Health Authorities n. 4; Local Health Authorities... and other collaborators

Completed

Life-long Monitoring of Frail Patients With Chronic Diseases

Multiple Chronic Diseases Among Diabetes Mellitus, Chronic Obstructive Pulmonary Diseases and Heart Failure

Italy
Consorci Sanitari del Maresme

Completed

Clinical and Economic Assessment of a Pre-frail Screening Program

Elderly | Pre-frail

Spain
Indonesia University

Unknown

Indonesia Frailty, Aging, and Longitudinal Study (INA-FRAGILE)

Quality of Life | Frailty

Indonesia
University of Pittsburgh
National Institutes of Health (NIH); National Institute on Aging (NIA)

Completed

Zoledronic Acid for Osteoporosis in the Elderly (ZEST)

Osteoporosis | Bone Loss | Fragility Fractures

United States
Novartis Pharmaceuticals

Completed

Safety and Efficacy of AFQ056 in Adolescent Patients With Fragile X Syndrome

Fragile X Syndrome

United States, Belgium, Australia, Israel, Switzerland, Germany, France, Canada, Denmark, Indonesia, Italy, Netherlands, Spain, Sweden, Turkey, United Kingdom
University Hospital, Toulouse

Completed

Omega-3 Fatty Acids and/or Multi-domain Intervention in the Prevention of Age-related Cognitive Decline (MAPT)

Frail Elderly Subjects

France, Monaco
Yolanda de Diego Otero

Completed

Safety and Efficacy Study of Antioxidants for the Treatment of the Fragile X Syndrome (SXF-TRA152)

Fragile X Syndrome

Spain
DSM Nutritional Products, Inc.

Completed

Dose Finding Study in Physically Frail Elderly to Measure 25(OH) Vitamin D Levels After Supplementation With Hy.D Calcifediol 25 SD/S and Vitamin D3 (D-DOSE)

Frail Elderly | Pre-frail Elderly

Netherlands
Michele Vitacca
Fondazione Salvatore Maugeri

Completed

Telemedicine for Patients With Chronic Respiratory Insufficiency

Chronic Respiratory Failure

Italy
Zealand University Hospital
Nykøbing Falster County Hospital; Region Zealand; Lolland Municipality; Guldborgsund... and other collaborators

Completed

Follow Home Visits After Discharge

Readmission | Discharge Planning | Hospital | Frail Elderly Patients

Denmark
Indonesia University

Completed

Frailty Status and Quality of Life in Elderly

Quality of Life | Frailty
National Medical Research Council (NMRC), Singapore
Alexandra Hospital; St Luke's Hospital, Singapore; National University of Singapore

Completed

Randomized Controlled Trial of Community-based Nutritional, Physical and Cognitive Training Intervention Programmes for At Risk Frail Elderly (FIT)

Pre-Frail or Frail State

Singapore
Vardalinstitutet The Swedish Institute for Health...
VinnVård

Completed

Continuum of Care for Frail Elderly People

Frail Elderly People

Sweden

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