Search clinical trials for: Japanese, GSK1322322, pharmacokinetics, relative bioavailability, single dose, repeat dose, healthy

Total 36494 results

Abant Izzet Baysal University

Not yet recruiting

The Effect of Perineal Care Education on Palliative Care Patient' Relatives

Healthy
Nanjing Zenshine Pharmaceuticals

Not yet recruiting

A Study to Evaluate the Effect of a Single Oral Dose of ZX-7101A on the QTc Interval in Healthy Subjects (QTc-ZX-7101A)

Influenza, Human

China
CSL Behring

Recruiting

First-In-Human Study To Evaluate The Safety, Tolerability, Pharmacokinetics, And Pharmacodynamics Of Escalating Single And Multiple Doses Of CSL040 In Healthy Subjects

Complement Deficiencies

Australia
Cerevel Therapeutics, LLC

Recruiting

A Study Evaluating the Pharmacokinetics and Relative Bioavailability of Emraclidine Immediate-Release Tablets in Healthy Adult Participants

Healthy Participants

United States
Nanjing Ruijie Pharma Co., Ltd.

Recruiting

Ascending Single-Dose and Multiple-Dose Study to Evaluate RJ4287 in Healthy Subjects

Drug Safety

China
Novo Nordisk A/S

Recruiting

A Research Study Looking at How a Single Dose of the Study Medicine NNC0194-0499 Behaves in Participants With Reduced Liver Function Compared to Participants With Normal Liver Function

Healthy Volunteers | Hepatic Impairment

Germany, Poland, Slovakia
Bill & Melinda Gates Medical Research Institute

Recruiting

Safety, Tolerability, Pharmacokinetics and Protective Efficacy of MAM01 in Healthy Adults

Malaria

United States
Cytokinetics

Recruiting

A Single and Multiple Ascending Dose Study of CK-4021586 in Healthy Adult Participants

Healthy Participants

United States
HealthPartners Institute

Recruiting

Measurement of Insulin Levels in Cerebral Spinal Fluid (CSF) of Healthy Adults After a Single Intranasal Dose (INI-CSF)

Healthy

United States
Medical College of Wisconsin
University of Oklahoma

Recruiting

Theophylline Prophylaxis During Hypothermia to Limit Neonatal Nephron Damage (TheoPHyLNNe)

Acute Kidney Injury | HIE

United States
Sirnaomics

Recruiting

Single Ascending Dose of FXI-GalNAc-siRNA in Healthy Subjects

FXI

United States, Canada
Aligos Therapeutics

Recruiting

A Study in Healthy Volunteers to Evaluate the Safety, Tolerability, Pharmacokinetics, and Drug-Drug Interaction Potential of Single and Multiple Doses of ALG-097558

COVID-19

United Kingdom
McMaster University

Recruiting

The Effects of Protein Supplementation With or Without Urolithin A During Single-leg Immobilization

Healthy | Muscle Disuse Atrophy

Canada
Fujian Shengdi Pharmaceutical Co., Ltd.

Recruiting

Clinical Study to Evaluate the Safety, Tolerance and Pharmacokinetic Characteristics of Single Administration of HRS-5635 Injection in Chinese Healthy Subjects and the Safety, Tolerance, Pharmacokinetics and Antiviral Effect of Multiple Administration in Patients With Chronic Hepatitis B

Chronic Hepatitis B

China
Assistance Publique - Hôpitaux de Paris

Recruiting

Efficacy and Safety of Obinutuzumab Versus Rituximab in Childhood Steroid Dependant and Frequent Relapsing Nephrotic Syndrome (OBIRINS)

Steroid-Dependent Nephrotic Syndrome | Steroid-Sensitive Nephrotic Syndrome

France
Beijing Airdoc Technology Co., Ltd.
The First People's Hospital of Xuzhou

Recruiting

Myopia Control Combined PBM With Myopic Defocus Lens in Children

Myopia, Progressive

China
National Institute of Allergy and Infectious Diseases...

Recruiting

A Study to Evaluate the Safety and Immunogenicity of a Single Dose of H1ssF-3928 mRNA-LNP in Healthy Adults

Influenza

United States
Zealand University Hospital

Recruiting

ITP Block: Single or Multiple Injection?

Anesthesia, Local

Denmark
Nirsum Labs
National Institute on Drug Abuse (NIDA)

Recruiting

Single Ascending Dose Study of NRS 033 in Healthy Volunteers

Healthy Volunteers

United States
Jiangsu HengRui Medicine Co., Ltd.

Recruiting

Bioequivalence Study of INS062 and Pharmacokinetics and Pharmacokinetics Study of Single Injection of HR20014 in Healthy Subjects

Diabetes

China
University of Reading
Wild Blueberry Association of North America (WBANA)

Recruiting

Effects of a Single Dose of Wild Blueberries on Mood and Executive Function in Healthy Emerging Adults

Executive Function | Mood | Affect

United Kingdom
Onconic Therapeutics Inc.

Not yet recruiting

Clinical Trial to Evaluate Food-Effects on Pharmacokinetics and Pharmacodynamics of Oral Single Dose of JP-1366 Tablet in Healthy Volunteers

Healthy

Korea, Republic of
GCS Ramsay Santé pour l'Enseignement et la Recherche

Not yet recruiting

Single-center Comparative Study of Variation in Acetabular Anteversion According to Pelvic Tilt in Patients With Femoro-acetabular Impingement and Healthy Volunteers. (VARIA-CFA)

Femoro-acetabular Impingement

France
argenx

Recruiting

A Clinical Trial to Investigate the Safety, Tolerability, Pharmacokinetics, and Immunogenicity of Single and Multiple Ascending Doses of ARGX-119 in Healthy Participants

Healthy Volunteers

Netherlands
AstraZeneca

Recruiting

A Study to Investigate the Safety, Tolerability, and Pharmacokinetics (PK) of Oral AZD6793 in Healthy Subjects and to Assess the Relative Oral Bioavailability Between Two Formulations. The Study Will Also Assess the Food Effect on the PK of AZD6793 Compared to Fasting State

Inflammatory Diseases

United Kingdom
Cytokinetics

Recruiting

A Single and Multiple Ascending Dose Study of CK-3828136 in Healthy Adult Participants

Healthy Participants

United States
Cedars-Sinai Medical Center
National Institute on Aging (NIA)

Recruiting

Single Nuclei RNA-seq to Map Adipose Cellular Populations and Senescent Cells in Older Subjects

Obesity | Healthy Lifestyle

United States
Suzhou Ribo Life Science Co. Ltd.

Recruiting

A Single Ascending Doses Phase I Study to Evaluate the Safety and Pharmacokinetics of RBD4059 in Healthy Subjects

Healthy Volunteers

Australia
University Hospital, Basel, Switzerland

Recruiting

The Influence of Demographic Parameters and ACL Injury on the Association Among Clinical, Functional and Biomechanical Parameters (MechBRACE)

Anterior Cruciate Ligament (ACL) Injury

Switzerland
University of Colorado, Denver
Temple University; Vitamix Foundation

Recruiting

Healthy Starts: Repeated Exposure Pilot

Feeding Behavior

United States
ViiV Healthcare

Recruiting

A Study to Investigate Safety, Tolerability, and Pharmacokinetics (PK) of VH4524184 and the Potential for Changes in Cytochrome P450 3A (CYP3A) Activity

HIV Infections

United States
Guangdong Hengrui Pharmaceutical Co., Ltd

Recruiting

Study on Single and Multiple Atomization Inhalation of HRS-9821 Suspension for Inhalation in Healthy Subjects

Chronic Obstructive Pulmonary Disease

China
IlDong Pharmaceutical Co Ltd
Parexel; YUNOVIA CO.,LTD.

Recruiting

Safety, Tolerability, and Pharmacokinetics of ID119031166M With the Exploration of Pharmacodynamic Effects

Healthy Participants

United States
Regeneron Pharmaceuticals

Recruiting

A Trial to Learn if Single Ascending Intravenous (IV) Doses of REGN7508 Are Safe and Well Tolerated, and How it Works in the Body of Healthy Adult Participants

Healthy Volunteer

United Kingdom
Sinew Pharma Inc.

Recruiting

A Partial Randomized, Single-blind or Open-label, Dose-escalation With Multiple-dose Design Study to Evaluate the Pharmacokinetics of Acetaminophen and Its Toxic Metabolites With Panadol® and SafeTynadol® in Healthy Volunteers

Hepatitis | Pharmacology

Taiwan
Novo Nordisk A/S

Recruiting

A Research Study Looking at How a Single Dose of the Medicine Cagrilintide Behaves in Participants With Reduced Liver Function and in Healthy Participants With Normal Liver Function

Hepatic Impairment

Germany, Slovakia
NeuroTrauma Sciences, LLC
Parexel

Recruiting

Single Ascending Dose Safety and Tolerability of NTS-104 Healthy Adults

Acute Ischemic Stroke

United States
Afasci Inc

Recruiting

Phase I Single Ascending Dose and Multiple Ascending Doses of Oral AFA-281 in Healthy Volunteers

Pain, Neuropathic | Pain, Inflammatory

United States
Godavari Biorefineries Limited

Not yet recruiting

Phase One Clinical Trial to Assess the Safety, Tolerability and Pharmacokinetics of MSP008-22 in Healthy Adult Volunteers

COVID-19

India
Indonesia University

Not yet recruiting

Preemptive Analgesia Combination of Celecoxib and Pregabalin in THA

Arthroplasty Complications | Pregabalin | Analgetic | Celecoxib
Eli Lilly and Company

Recruiting

A Study of LY3873862 in Healthy Participants

Healthy

United Kingdom
Henry Ford Health System

Recruiting

Opioid-Free Pain Protocol After Shoulder Arthroplasty

Shoulder Pain | Shoulder Arthropathy

United States
Intra-Cellular Therapies, Inc.
National Institute on Drug Abuse (NIDA)

Recruiting

A PET Study Following a Single Oral Dose of ITI-333 in Healthy Subjects

Healthy Volunteers

United States
United States Army Research Institute of Environmental...

Recruiting

The Effects of Cold Adaptation on Skin Blood Flow, Hand Function, and Comfort in Healthy Adults

Cold Exposure

United States
NEURALIS s.a.

Recruiting

Single and Multiple Intravenous Administrations of Estetrol (E4) in Healthy Adult Volunteers

Pharmacokinetics | Safety

Bulgaria
Pacira Pharmaceuticals, Inc

Recruiting

Phase 1, Dose Escalation Study to Evaluate of Safety, Pharmacokinetics and Pharmacodynamics of Liposomal Bupivacaine 13.3 Administered Via a Single Intrathecal Injection to Healthy Volunteers

Healthy

United States
Bangabandhu Sheikh Mujib Medical University, Dhaka...

Recruiting

Influence of Ethnicity and ABCB1 Gene Polymorphism on the Pharmacokinetics of Azithromycin in Healthy Bangladeshi Volunteers

Comparative Bioavailability Study

Bangladesh
Eli Lilly and Company

Recruiting

A Single-Ascending and Repeated Dose Study of LY3849891 in Participants With Nonalcoholic Fatty Liver Disease

Non-Alcoholic Fatty Liver Disease

United States, Japan
Newsoara Biopharma Co., Ltd.

Recruiting

Safety, Tolerance and Pharmacokinetics of THR-1442 in Chinese Healthy Subjects

T2DM (Type 2 Diabetes Mellitus)

China
Genoscience Pharma

Not yet recruiting

Effect of Food and Formulation on the Pharmacokinetics, Safety, and Tolerability of GNS561 After One Single Dose (50 and 200mg) in Healthy Volunteers

Primary Liver Cancer

France

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