Search clinical trials for: Moderate renal impairment

Total 26737 results

Genfit

Completed

Nitazoxanide Pharmacokinetic Parameters in Hepatic Impaired Patients

Liver Diseases | Moderate Hepatic Impairment | Severe Hepatic Impairment

United States
St. Jude Children's Research Hospital
Assisi Foundation; Cookies for Kids' Cancer

Completed

Therapy for Pediatric Relapsed or Refractory Precursor B-Cell Acute Lymphoblastic Leukemia and Lymphoma

Recurrent B-Cell Childhood Acute Lymphoblastic Leukemia | Recurrent Childhood B-Lymphoblastic Lymphoma

United States
National Tainan Junior College of Nursing

Completed

Effect of the Group-based Paro Intervention on Physiological and Psychological Outcomes

Cognitive Impairment | Dementia, Mild | Dementia Moderate

Taiwan
Rush University Medical Center

Withdrawn

Low-moderate Intensity Pedaling During Immunotherapy Administration

Immunotherapy | Cancer of Skin | Exercise, Aerobic | Cancer of Kidney | Cancer of Bladder

United States
AbbVie
Roche-Genentech

Completed

Study to Assess Adverse Events and the Movement of Oral Venetoclax Tablet Through the Body of Female Participants Aged 18-75 Years With Impaired Renal Function

Renal Impairment | Renal Disease

United States
Albert Einstein College of Medicine

Withdrawn

Safety and Efficacy of Apixaban in Severe Renal Impairment

Anticoagulant-induced Bleeding | Renal Disease, End Stage

United States
Bayer

Terminated

Study to Learn More About the Effect of a New Drug Called BAY2327949 on the Blood Flow Through Kidneys in Adult Participants With Moderate Chronic Kidney Disease

Moderate Chronic Kidney Disease

Denmark
Incyte Corporation

Completed

To Evaluate the Safety, and Pharmacokinetics of Parscaclisib in Participants With Normal Renal Function and Renal Impairment.

Advanced Malignancies

United States
Arthrosi Therapeutics
Iqvia Pty Ltd

Completed

Pharmacokinetic Study of AR882 in Subjects With Various Degrees of Renal Impairment

Renal Impairment

United States, New Zealand
National Central University

Completed

Autonomic Modulation After Spinal Anesthesia With Depth of Anesthesia and Vital Signs.

Participants Scheduled for Surgery Under Spinal Anesthesia Without Impairment of Renal, Hepatic, Cardiac or Respiratory Function

Taiwan
Amgen

Completed

Study of Romosozumab (AMG 785) Administered to Healthy Participants and Patients With Stage 4 Renal Impairment or Stage 5 Renal Impairment Requiring Hemodialysis

Osteoporosis

United States
Akebia Therapeutics

Completed

20-Week Repeat Oral Dose Study of AKB-6548 in Participants With Chronic Kidney Disease and Anemia

Anemia | Chronic Kidney Disease

United States
Akebia Therapeutics

Completed

Efficacy and Safety Study to Evaluate Vadadustat for the Correction or Maintenance Treatment of Anemia in Participants With Incident Dialysis-dependent Chronic Kidney Disease (DD-CKD)

Anemia | Dialysis-Dependent Chronic Kidney Disease

United States, Italy, Korea, Republic of, Portugal, Russian Federation, Ukraine, Poland, Argentina, Brazil, Germany, Mexico
Janssen-Cilag International NV

Terminated

A Study of Orally Administered Pimodivir in Adult Participants With Renal Impairment

Kidney Failure, Chronic

Germany
Akebia Therapeutics

Completed

16-Week Repeat Oral Dose Study of AKB-6548 for Anemia in Participants With End Stage Renal Disease (ESRD) Requiring Chronic Hemodialysis

Anemia | End Stage Renal Disease

United States
Akebia Therapeutics

Completed

42-Day Repeat Oral Dose Study of AKB-6548 in Participants With Chronic Kidney Disease and Anemia

Anemia | Kidney Disease

United States
Akebia Therapeutics

Completed

Safety and Efficacy Study for AKB-6548 in Participants With Chronic Kidney Disease and Anemia

Anemia | Kidney Disease

United States
Yuhan Corporation

Completed

A Study to Evaluate the Pharmacokinetics and Safety of YHD1119 in Subjects With Renal Impairment and Healthy Subjects

Healthy Volunteer | Renal Impairments

Korea, Republic of
Allecra

Completed

Pharmacokinetics of Cefepime and AAI101 in Subjects With Renal Insufficiency and Healthy Subjects

PK in Patients With Various Degrees of Renal Impairment

Czechia, Hungary
Akebia Therapeutics

Completed

Efficacy and Safety Study to Evaluate Vadadustat for the Maintenance Treatment of Anemia in Participants With Dialysis-dependent Chronic Kidney Disease (DD-CKD)

Anemia | Dialysis-Dependent Chronic Kidney Disease

United States, Italy, Canada, Korea, Republic of, United Kingdom, Australia, Germany, Israel, France, Portugal, Bulgaria, Russian Federation, Ukraine, Poland, Brazil, Argentina, Mexico, Serbia
Can-Fite BioPharma

Completed

CF101 Therapy in Patients With Moderate-to-severe Plaque Psoriasis

Plaque Psoriasis

Israel, Serbia, Romania, Croatia, Bosnia and Herzegovina, Bulgaria, Canada, Moldova, Republic of, Poland
Akebia Therapeutics

Completed

Efficacy and Safety Study to Evaluate Vadadustat for the Maintenance Treatment of Anemia in Participants With Non-dialysis-dependent Chronic Kidney Disease (NDD-CKD)

Anemia | Non-Dialysis-Dependent Chronic Kidney Disease

United States, Italy, Spain, Czechia, Korea, Republic of, Malaysia, Australia, New Zealand, United Kingdom, Germany, Turkey, Ukraine, France, Hungary, Austria, Israel, Bulgaria, Russian Federation, Romania, Slovakia, South Africa, Canad... and more
Akebia Therapeutics

Completed

Study to Evaluate Vadadustat for the Correction of Anemia in Participants With Non-dialysis-dependent Chronic Kidney Disease

Anemia | Non-Dialysis-Dependent Chronic Kidney Disease

United States, Italy, Korea, Republic of, Australia, New Zealand, South Africa, United Kingdom, Spain, Ukraine, Hungary, Israel, Bulgaria, Russian Federation, Mexico, Poland, Brazil, Argentina, Malaysia, Puerto Rico, France
Amgen

Completed

Study to Evaluate the Safety, Tolerability and Pharmacokinetics of AMG 986 Administered Orally to Healthy Volunteers and Participants With Severely Impaired Renal Function

Heart Failure

United States
Bristol-Myers Squibb

Completed

A Study to Evaluate the Drug Levels, Safety, and Tolerability of BMS-986036 in Participants With Normal Liver Function and Participants With Moderate and Severe Liver Impairment

Moderate Liver Impairment | Severe Liver Impairment

United States
Celgene

Completed

A Phase 1, Multicenter, Open-Label Study to Evaluate the Effect of Mild or Moderate Hepatic Impairment on the Multiple-Dose Pharmacokinetics of Ozanimod

Liver Diseases | Digestive System Diseases

United States
Galera Therapeutics, Inc.

Completed

Study to Evaluate the Effects of Renal Impairment on the Pharmacokinetics, Safety and Tolerability of GC4419

Renal Impairment

United States
Universitätsklinikum Hamburg-Eppendorf

Completed

Daratumumab in Combination With Bortezomib and Dexamethasone in Subjects With Relapsed or Relapsed and Refractory Multiple Myeloma and Severe Renal Impairment (GMMG-DANTE)

Multiple Myeloma

Germany, Greece
Institut Pasteur
Institut Pasteur de Madagascar; Action Contre la Faim; Centre de Recherches Médicales... and other collaborators

Completed

Comparing Several Strategies to Manage Moderate Acute Malnutrition Among Children From 6 to 24 Months Old (MALINEA)

Moderate Acute Malnutrition

Central African Republic, Madagascar, Niger, Senegal
CSPC ZhongQi Pharmaceutical Technology Co., Ltd.

Completed

A Study to Evaluate the Pharmacokinetics and Safety of DBPR108 in Subjects With Renal Impairment

Renal Impairment

China
Vanderbilt University Medical Center

Completed

Nicotine Treatment of Cognitive Decline in Down Syndrome

Down Syndrome | Mild Cognitive Impairment

United States
Vastra Gotaland Region

Completed

Eye and Growth in Adolescents Born Moderate-to-late Preterm

Eye Abnormalities | Preterm Birth | Visual Impairment

Sweden
BioAge Labs, Inc.

Withdrawn

Study to Evaluate Efficacy and Safety of BGE-117 in Moderately to Severely Anemic Older Individuals After Major Hip Surgery

Acute Posthemorrhagic Anemia

Australia
Cara Therapeutics, Inc.

Completed

A Study to Evaluate the Safety and Efficacy of CR845 in Hemodialysis Patients With Moderate-to-Severe Pruritus (KALM-1)

Uremic Pruritus

United States
Cara Therapeutics, Inc.

Completed

CR845-CLIN3103: A Global Study to Evaluate the Safety and Efficacy of CR845 in Hemodialysis Patients With Moderate-to-Severe Pruritus (KALM-2)

Uremic Pruritus

United States, Canada, Czechia, Australia, Germany, Hungary, Korea, Republic of, New Zealand, Poland, Taiwan, United Kingdom
Genzyme, a Sanofi Company

Completed

Effect of Venglustat in Patients With Renal Impairment

Healthy Volunteers | Polycystic Kidney, Autosomal Dominant

United States
AstraZeneca
Parexel

Completed

A Study to Assess the Pharmacokinetics (Uptake of Drugs by the Body), Safety and Tolerability of AZD4831 in Participants With Severe Renal Impairment and Healthy Volunteers

Renal Impairment

Bulgaria
Pfizer

Completed

A Renal Impairment Study for PF-04965842

Renal Impairment

United States, Belgium
AstraZeneca

Completed

Study to Assess the Pharmacokinetics and Safety of AZD9977 in Participants With Renal Impairment

Renal Impairment

United States
Mylan Inc.
Theravance Biopharma

Completed

Pharmacokinetics of TD-4208 in Patients With Moderate Hepatic Impairment

Hepatic Impairment

United States
Mylan Inc.
Theravance Biopharma

Completed

Pharmacokinetics of TD-4208 in Patients With Severe Renal Impairment

Renal Impairment

United States
Assiut University

Completed

Kidney Affection in Non Alcaholic Fatty Liver Diseases

Renal Impairment

Egypt
Bayer

Completed

BAY94-8862 Dose Finding Trial in Subjects With Chronic Heart Failure and Mild (Part A) or Moderate (Part B) Chronic Kidney Disease (ARTS)

Heart Failure

Denmark, Germany, Belgium, Austria, Czechia, Israel, Norway, Sweden, Poland, Finland
Ohio State University

Completed

Robotic Brace Incorporating Electromyography for Moderate Affected Arm Impairment After Stroke

Hemiparesis

United States
Innocoll
Premier Research Group plc

Completed

The Safety and Efficacy of an Antibiotic Sponge in Diabetic Patients With Moderately Infected Foot Ulcers

Diabetic Foot Ulcer

United States
Bayer

Completed

Study to Assess the Safety, Tolerability, Effects on the Body, Absorption, Distribution and Elimination of 25 mg BAY2433334 in Renal Impairment Including Renal Replacement Therapy ("Dialysis")

Prevention of Thromboembolic Events

Germany
Acacia Pharma Ltd

Completed

PK Study of IV and Oral Amisulpride in Subjects With Severe Renal Impairment

Renal Disease, End Stage

United States
Idorsia Pharmaceuticals Ltd.

Completed

A Study to Investigate the Pharmacokinetics of ACT-1014-6470 in Subjects With Severe Renal Impairment Compared to Control Subjects

Healthy

Germany
The University of Hong Kong

Completed

Effectiveness of Walking Exercise in Improving Cognitive Function in Older Adults With Mild Cognitive Impairment

Mild Cognitive Impairment

Hong Kong
Hennepin Healthcare Research Institute
Mayo Clinic; Minneapolis Veterans Affairs Medical Center; National Institute... and other collaborators

Active, not recruiting

BRINK (BRain In Kidney Disease) Memory Study 2.0 (BRINK)

Stroke | Kidney Diseases | Diabetes | Chronic Kidney Diseases | Cognitive Impairment | Cognitive Dysfunction | Dementia | Alzheimer Disease | Dementia, Vascular | Cognitive Decline | Cerebral Atrophy | Small Vessel Ischemic Disease

United States

Search clinical trials for: Moderate renal impairment

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