Search clinical trials for: Nicotine Pharmacodynamics

Total 4500 results

Brown University
National Institute of General Medical Sciences (NIGMS)

Recruiting

E-cigarettes for Harm Reduction in Adults With Asthma (SWAP)

Smoking | Asthma | Electronic Cigarette Use | Cigarette Smoking

United States
ViGenCell Inc.

Not yet recruiting

A Prospective, Open Label, Dose-escalation, SAD/MAD, Multicenter, 24weeks, Phase I/IIa Clinical Trial to Evaluate the Safety, Tolerability and Pharmacodynamics of Investigational Product (VM-001) in Patients With Graft-versus-host Disease(GvHD)

Graft Versus Host Disease
Umeå University
Karolinska Institutet; Lund University; Göteborg University; Linkoeping University and other collaborators

Recruiting

The Glaucoma Nicotinamide Trial (TGNT)

Glaucoma

Sweden
The University of Texas Health Science Center,...

Recruiting

Circuitry-Guided Smoking Cessation in Schizophrenia (UH3)

Smoking Cessation | Schizophrenia | Nicotine Addiction

United States
Hoffmann-La Roche
Chugai Pharmaceutical

Recruiting

A Study to Evaluate the Efficacy, Safety, Pharmacokinetics, and Pharmacodynamics of Satralizumab in Patients With Myelin Oligodendrocyte Glycoprotein Antibody-Associated Disease (Meteoroid)

Myelin Oligodendrocyte Glycoprotein Antibody-Associated Disease (MOGAD)

Canada, United States, Korea, Republic of, Australia, Japan, Italy, Brazil, Germany, France, China, Israel
University of Pennsylvania
National Heart, Lung, and Blood Institute (NHLBI); National Institutes of Health...

Recruiting

MRI and Biological Markers of Acute E-Cigarette Exposure in Smokers and Vapers (AeCE)

Serum Biomarkers | Vascular Reactivity

United States
Sir Mortimer B. Davis - Jewish General Hospital

Recruiting

Aggressive Smoking Cessation Trial (ASAP) (ASAP)

Cardiovascular Diseases | Acute Coronary Syndrome

Canada
Enzene Biosciences Ltd.
Alkem Laboratories Ltd

Recruiting

Study to Compare the Pharmacokinetics, Pharmacodynamics, Safety, Tolerability, and Immunogenicity of Biosimilar Denosumab With Prolia® in Healthy Adult Male Volunteers

Healthy Male Subjects

Bulgaria, Poland
Roskamp Institute Inc.
United States Department of Defense; Nova Southeastern University

Recruiting

Nicotinamide Riboside Clinical Trial for GWI

Gulf War Illness

United States
Mansoura University

Not yet recruiting

Effect of Local Anesthesia Versus Induced Hypotensive Anesthesia on Quality of External Dacryocystorhinostomy Operation

Patient With Nasolacrimal Duct Obstruction | External Dacryocystorhinostomy Operation

Egypt
University of Oklahoma
H. Lee Moffitt Cancer Center and Research Institute; Setthathirath Hospital... and other collaborators

Recruiting

Mobile Health Technology for Personalized Tobacco Cessation Support in Laos (SupportLaos)

Cigarette Smoking

Lao People's Democratic Republic
The Affiliated Hospital of Qingdao University

Recruiting

Tolerance, Pharmacokinetics / Pharmacodynamics (PK / PD) and Immunogenicity of Pegylated Uric Acid Oxidase for Injection in Healthy Adults and Hyperuricemia Volunteers

Hyperuricemia

China
Rowan University
University of Kentucky

Recruiting

Re-Connect Application for Smoking Cessation

Smoking Cessation | Nicotine Dependence, Cigarettes | Acceptability of Health Care

United States
Novartis Pharmaceuticals

Recruiting

Pharmacokinetics, Pharmacodynamics, Safety and Tolerability of Glycopyrronium (Bromide) in Children (6 to Less Than 12 Years) With Asthma

Asthma

Spain, Hungary, United Kingdom, South Africa, Colombia, Guatemala, Bulgaria, Poland
Boehringer Ingelheim

Recruiting

A Study to Test Long-term Safety of Iclepertin in People With Schizophrenia Who Took Part in a Previous CONNEX Study

Schizophrenia

Korea, Republic of, Canada, United States, Taiwan, United Kingdom, Chile, Serbia, Brazil, China, Colombia, Germany, Greece, Italy, Japan, Mexico, Norway, Poland, Sweden, Spain, Argentina, Croatia, France, Slovakia, Denmark, Australia, Mal... and more
Florida International University

Recruiting

Assessing the Effect of Nicotine Reduction on ENDS User's Addiction and Exposures

Electronic Cigarette Use

United States
Butler Hospital
National Institute on Drug Abuse (NIDA)

Recruiting

Methadone-Maintained Smokers Switching to E-Cigarettes (SHINE)

Electronic Cigarette Use | Nicotine Dependence

United States
Antengene Therapeutics Limited
Merck Sharp & Dohme LLC

Recruiting

A Study to Assess the Safety, Pharmacokinetics, Pharmacodynamics, and Preliminary Efficacy of ATG 037 Monotherapy and Combination Therapy With Pembrolizumab in Patients With Advanced Solid Tumors

Locally Advanced or Metastatic Solid Tumors

Australia, China
Hoffmann-La Roche

Recruiting

A Study To Evaluate Pharmacokinetics, Efficacy, Safety, Tolerability, And Pharmacodynamics Of Satralizumab In Pediatric Patients With Aquaporin-4 Antibody Positive Neuromyelitis Optica Spectrum Disorder (NMOSD) (SAkuraSun)

Neuromyelitis Optica Spectrum Disorder | NMOSD

Poland, United Kingdom, Argentina, Italy, France, United States
Shanghai Hengrui Pharmaceutical Co., Ltd.

Not yet recruiting

A STUDY TO EVALUATE THE SAFETY, TOLERABILITY, PHARMACOKINETICS, AND PHARMACODYNAMICS OF MULTIPLE SUBCUTANEOUS INJECTIONS OF SHR-1819 IN PATIENTS WITH MODERATE TO SEVERE ATOPIC DERMATITIS

Moderate to Severe Atopic Dermatitis
Children's Hospital of Philadelphia
National Cancer Institute (NCI); University of Pennsylvania; City of Hope Medical... and other collaborators

Recruiting

Exercise Training and NR Supplementation Trial to Improve Fitness in AYA HCT Survivors (IAMFIT)

Myelodysplastic Syndromes | Aplastic Anemia | Lymphoblastic Leukemia | Cancer Survivors

United States
Luzerner Kantonsspital

Recruiting

Preoperative Smoking Cessation in Patients Undergoing Surgery (PORTICO)

Smoking | Smoking Cessation | Postoperative Complications | Cancer | Head and Neck Cancer | Gynecologic Cancer | Smoking Reduction | Surgery | Surgery--Complications | Thoracic Cancer | Abdominal Cancer | Urologic Cancer | Perioperative Complication

Switzerland
Washington State University

Recruiting

Pharmaceutically-Enhanced Reinforcement for Reduced Alcohol and Smoking (PERRAS)

Nicotine Use Disorder | Alcohol Use Disorder (AUD)

United States
Vedic Lifesciences Pvt. Ltd.

Recruiting

Study to Evaluate the Effect of Nicotinamide Mononucleotide (NMN) As an Adjuvant to Standard of Care (SOC) On Fatigue Associated With COVID-19 Infection

COVID-19 Infection

India
Yale University

Recruiting

IV Pulsed-Nicotine as a Model of Smoking: The Effects of Dose and Delivery Rate

Nicotine Dependence

United States
Fulcrum Therapeutics

Recruiting

Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of FTX-6058

Sickle Cell Disease | Sickle Cell Anemia

United States
NYU Langone Health
National Cancer Institute (NCI)

Recruiting

Integrating Financial Coaching and Smoking Cessation Coaching

Smoking

United States
Centre Hospitalier Universitaire, Amiens

Recruiting

Effect of Oral Water in Healthy Volunteers on Cardiac Output, Regional Flow and Microcirculation in Healthy Volunteers (WATERNAL)

Fluid Therapy | Pharmacodynamics | Fluid Responsiveness | Fluid Challenge | Intravenous Fluids

France
Tanta University

Recruiting

Continuous Infusion Versus Intermittent Boluses of Cisatracurium in the Early Management of Pediatric ARDS

Acute Lung Injury/Acute Respiratory Distress Syndrome (ARDS) | Respiratory Distress Syndrome, Pediatric

Egypt
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Recruiting

Risk and Benefits of Electronic Cigarettes to Older Smokers at High Risk for Lung Cancer

Lung Carcinoma

United States
Vance Thompson Vision - MT

Not yet recruiting

IIT Assessing OC-01Nasal Spray on Symptoms of DED Following CXL

Dry Eye Disease

United States
NYU Langone Health
National Institute on Minority Health and Health Disparities (NIMHD); Asian... and other collaborators

Recruiting

WeChat Quit Coach Pilot Study

Smoking Cessation

United States
The Second Affiliated Hospital of Chongqing Medical...

Recruiting

Population Pharmacokinetic - Pharmacodynamic Models of Chronic Disease Therapeutics for Smokers

Smoking | Chronic Disease

China
Cambridge Health Alliance
National Cancer Institute (NCI); National Center for Complementary and Integrative...

Recruiting

Patients' Attitudes Toward and Experiences With Buprenorphine Treatment

Opioid-Related Disorders | Opioid-use Disorder | Acceptability of Health Care

United States
University of Manitoba
Johns Hopkins University; University Health Network, Toronto; University of California... and other collaborators

Recruiting

International Milk Composition (IMiC) Consortium (IMiC)

Maternal Health | Infant Growth | Infant Nutrition

Canada
RAI Services Company

Recruiting

CSD201203: A Study to Determine Subject Puffing Patterns of a Non-cylindrical, Closed, Electronic Nicotine Delivery System at Three Nicotine Concentrations in an Ambulatory Setting

Smoking | Tobacco Use | Electronic Cigarette Use

United States
CSPC ZhongQi Pharmaceutical Technology Co., Ltd.

Not yet recruiting

A Study To Evaluate the Safety, Tolerance, Pharmacokinetics/Pharmacodynamics and Efficacy of SYHA1402 Tablets For the Treatment of Patients With Diabetic Peripheral Neuropathy in China

Distal Symmetric Polyneuropathy (DSPN)
Andrew Strasser
National Institute on Drug Abuse (NIDA); Food and Drug Administration (FDA); Rutgers...

Recruiting

Impact of Nicotine Messaging on Beliefs and Behavior

Cigarette Smoking | Smoking Behaviors

United States
Montreal Heart Institute
Institut de Recherches Cliniques de Montreal

Recruiting

Assessing Pharmacokinetics and Pharmacodynamics of Daily Enteric-coated Aspirin in Patients With StablE Diabetes (APPEASED)

Diabetes Mellitus, Type 2

Canada
Federal Stare Budgetary Scientific Institution,...
Kazan State Medical University; Federal State Budgetary Institution V.M. Bekhterev...

Recruiting

Seroquel ® in Patients With Bipolar Disorder in Remission With Signs of Impaired Impulse Control

Bipolar Affective Disorder

Russian Federation
Haukeland University Hospital
Elysium Health

Recruiting

A Trial of Nicotinamide/Pterostilbene Supplement in ALS: The NO-ALS Extension Study

Amyotrophic Lateral Sclerosis

Norway
Enteris BioPharma Inc.
Syneos Health; Parexel

Recruiting

Study to Evaluate the Pharmacodynamics and Efficacy of Leuprolide Tablets (Ovarest®) in Women With Endometriosis

Endometriosis

United States
Université de Sherbrooke

Recruiting

Brown Adipose Tissue Metabolism in Type 2 Diabetes (GB8)

Type 2 Diabetes

Canada
Hoffmann-La Roche

Recruiting

A Study Evaluating the Efficacy, Safety, Pharmacokinetics, and Pharmacodynamics of Crovalimab as Adjunct Treatment in Prevention of Vaso-Occlusive Episodes (VOE) in Sickle Cell Disease (SCD) (CROSSWALK-c)

Sickle Cell Disease

Spain, United States, Brazil, United Kingdom, Italy, Turkey, Kenya, Netherlands, France, South Africa, Lebanon
Maxinovel Pty., Ltd.

Recruiting

A Study to Evaluate the Safety and Tolerability, Pharmacokinetics, Pharmacodynamics and Preliminary Efficacy of Max-40279-01 in Combination With Azacitidine (AZA) in Patients With Myelodysplastic Syndrome (MDS) or Relapsed/Refractory Acute Myeloid Leukemia (R/R AML)

Acute Myeloid Leukemia | Leukemia | Myelodysplastic Syndrome | Relapsed/Refractory Acute Myeloid Leukemia

China
Brandon Baartman

Recruiting

Investigator Initiated Study to Assess the Efficacy of OC-01 (Varenicline) Nasal Spray on Signs and Symptoms of Dry Eye Disease Following Photorefractive Keratectomy (PRK)

Dry Eye

United States
University of Oxford

Recruiting

Finding Treatments for COVID-19: A Trial of Antiviral Pharmacodynamics in Early Symptomatic COVID-19 (PLATCOV) (PLATCOV)

COVID-19

Lao People's Democratic Republic, Thailand, Brazil, Pakistan
Duke University
National Institute on Drug Abuse (NIDA); National Institutes of Health (NIH); University at Buffalo

Recruiting

Comparing Two Behavioral Approaches to Quitting Smoking in Mental Health Settings (MTQT)

Schizophrenia | Schizoaffective Disorder | Tobacco Use Disorder | Bipolar Disorder | Mental Illness | Persistent Depressive Disorder | Recurring Major Depressive Disorder

United States
University of Miami

Recruiting

Testing Integrative Smoking Cessation for HIV Patients

HIV Infections | Smoking | Smoking Cessation

United States
Qilu Hospital of Shandong University

Not yet recruiting

Prolonged Intravenous Infusion of β-lactam Antibiotics in Early Septic Patients (PROBES)

Sepsis

Search clinical trials for: Nicotine Pharmacodynamics

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