Search clinical trials for: Oral Proteolytic and Hydrolytic Enzymes

Total 472824 results

Janssen Pharmaceutical K.K.

Completed

A Phase 4 Study to Evaluate Pharmacokinetics and Safety of Darunavir Along With Ritonavir in Healthy Male Japanese Participants

Healthy

Japan
Western Galilee Hospital-Nahariya

Unknown

Safety and Efficacy of Oral Versus Intravenous Amiodarone in the Treatment of AF

Atrial Fibrillation

Israel
Alcon Research

Completed

Topical Treatment of Acute Otitis Media Through Tympanostomy Tubes (AOMT) and Its Effect on Microbial Flora

Acute Otitis Media

United States
Pfizer

Completed

Study Evaluating The Safety And Tolerability Of Administration Of Single Oral Doses Of SAM-760 To Healthy Subjects

Healthy

France
Pfizer

Withdrawn

Study Evaluating Tigecycline Versus Ceftriaxone In Complicated Intra-Abdominal Infections & Community Acquired Pneumonia

Community Acquired Bacterial Pneumonia | Complicated Intra-Abdominal Infection
Dallas VA Medical Center
Otsuka Pharmaceutical Development & Commercialization, Inc.

Unknown

Standard Triple Therapy vs Sequential Therapy in Treatment of H Pylori Infection

Helicobacter Infection

United States
National Institute of Allergy and Infectious Diseases...
Eunice Kennedy Shriver National Institute of Child Health and Human Development...

Completed

Depo-Medroxyprogesterone Acetate (DMPA, Depo-Provera) Use With Certain Anti-HIV Drugs in HIV-Infected Women

HIV Infections

United States, Puerto Rico
Halmstad County Hospital

Completed

Orally Administered Trimethoprim-sulfamethoxazole and Metronidazole as Prophylaxis of Infection Following Elective Colorectal Surgery

Infection Prophylaxis in Colo Rectal Surgery

Sweden
European Organisation for Research and Treatment...

Terminated

Moxifloxacin Compared With Ciprofloxacin/Amoxicillin in Treating Fever and Neutropenia in Patients With Cancer

Lymphoma | Myelodysplastic Syndromes | Leukemia | Chronic Myeloproliferative Disorders | Neutropenia | Unspecified Adult Solid Tumor, Protocol Specific | Infection | Multiple Myeloma and Plasma Cell Neoplasm | Precancerous Condition | Fever, Sweats, and Hot Flashes | Myelodysplastic/Myeloproliferative Neoplasms

France, Switzerland, Belgium, Germany, Italy, Israel, Slovakia, Turkey
Inje University

Completed

Effects of Clopidogrel and Clarithromycin on the Oral Disposition of Sibutramine in Healthy Subjects (sibu)

Healthy
University of Alabama at Birmingham
Bristol-Myers Squibb

Completed

The Bioequivalence of Atripla in an Oral Liquid Formulation Compared With the Tablet Formulation in Healthy Volunteers

Healthy

United States
Babylon University
Ministry of Health, Iraq

Completed

Study the Effect of Oral Zinc Supplementation on Enzymes of Nitric Oxide Pathway

Asthenozoospermia

Iraq
M.D. Anderson Cancer Center

Completed

Liposomal Amphotericin B (Ambisome) Versus Oral Voriconazole for the Prevention of Invasive Fungal Infections

Myelodysplastic Syndrome | Acute Myelogenous Leukemia

United States
Alcon Research

Completed

Effect on Wound Healing of Vigamox Versus Cravit

Cataract Extraction

Korea, Republic of
Wyeth is now a wholly owned subsidiary of Pfizer

Withdrawn

Study Evaluating Tigecycline Versus Ceftriaxone In Complicated Intra-Abdominal Infections & Community Acquired Pneumonia

Community Acquired Bacterial Pneumonia | Complicated Intra-Abdominal Infection
GlaxoSmithKline

Completed

A Study of the Effects of Ketoconazole Taken Orally Has on the PK Profiles of a Dose of GSK189075 in Healthy Volunteers

Diabetes Mellitus, Type 2 | Type 2 Diabetes Mellitus

United States
University of Witwatersrand, South Africa

Terminated

Differences Between Stavudine and Tenofovir Each Combined With Lamivudine and Efavirenz in SA HIV-infected Patients (CHRU01)

Metabolic Complications | Mitochondrial Toxicity

South Africa
National Institute of Allergy and Infectious Diseases...

Completed

Study of Anti-HIV Therapy Intensification

HIV Infections

United States
IASO Pharma Inc.

Terminated

Safety and Efficacy Study of Oral Zabofloxacin in Community Acquired Pneumonia

Community Acquired Pneumonia

United States
Kirby Institute
National Heart, Lung, and Blood Institute (NHLBI); St Vincent's Hospital, Sydney

Completed

HIV Infection And Metabolic Abnormalities Protocol 1 (HAMA001)

Cardiovascular Disease | HIV-Associated Lipodystrophy Syndrome

Australia
Zhejiang University
Guangdong Provincial People's Hospital; Shanghai General Hospital, Shanghai... and other collaborators

Completed

Efficacy of Itraconazole as Secondary Prophylaxis in Patients Undergoing Allogeneic Stem Cell Transplantation or Chemotherapy With Prior Invasive Fungal Infection

Invasive Fungal Infection

China
Stiefel, a GSK Company

Completed

An Open Label Trial to Assess the Safety and Efficacy of Oral R115866 in the Treatment Facial Acne

Acne

Belgium, Netherlands
Novartis Pharmaceuticals

Terminated

An Exploratory Study to Assess Multiple Doses of Omalizumab in Patients With Cystic Fibrosis Complicated by Acute Bronchopulmonary Aspergillosis (ABPA)

Cystic Fibrosis | Allergic Bronchopulmonary Aspergillosis

United Kingdom, Germany, Belgium, Italy, Netherlands
Universitaire Ziekenhuizen KU Leuven

Completed

Comparison of 2 Treatment Regimens for Eradication of P Aeruginosa Infection in Children With Cystic Fibrosis (CCTOBI)

Cystic Fibrosis

Belgium
Taipei Medical University Hospital
National Health Research Institutes, Taiwan

Completed

Treatment Strategy for Refractory Schizophrenia: Drug Interaction Between Clozapine and Fluvoxamine

Schizophrenia

Taiwan
Johnson & Johnson Pharmaceutical Research & Development...
PriCara, Unit of Ortho-McNeil, Inc.

Completed

A Study of the Safety and Effectiveness of Oral Levofloxacin Compared With Cefuroxime Axetil in the Treatment of Adults With Persistent Bronchitis Experiencing Rapid Onset of Severe Worsening of Symptoms Caused by Bacteria

Bronchitis, Chronic
Johnson & Johnson Pharmaceutical Research & Development...
PriCara, Unit of Ortho-McNeil, Inc.

Completed

A Study of the Safety and Effectiveness of Oral Levofloxacin Compared With Oral Ciprofloxacin in the Treatment of Adults With Uncomplicated Infections of the Skin and the Supportive Layers Beneath the Skin

Skin Diseases, Infectious
Johnson & Johnson Pharmaceutical Research & Development...
PriCara, Unit of Ortho-McNeil, Inc.

Completed

A Study of the Safety and Effectiveness of Oral Levofloxacin Compared With Oral Ciprofloxacin in the Treatment of Adults With Mild to Moderate Infections of the Skin and the Supportive Layers Beneath the Skin

Skin Diseases, Infectious | Cellulitis
Johnson & Johnson Pharmaceutical Research & Development...
PriCara, Unit of Ortho-McNeil, Inc.

Completed

A Study of the Safety and Effectiveness of Oral Levofloxacin Compared With Oral Ciprofloxacin in the Treatment of Complicated Urinary Tract Infections

Urologic Diseases | Bacteriuria | Urinary Tract Infections | Pyelonephritis | Neurogenic Bladder
Ortho-McNeil Janssen Scientific Affairs, LLC

Completed

Evaluation of Bacteria in the Mouth and Throat of Healthy Adults Before and After the Administration of Either Levofloxacin or Azithromycin, Both Antibiotic Medications

Healthy Volunteer
Pfizer

Completed

A Clinical Study Intended To Compare Treatment With Voriconazole To Treatment With Amphotericin Followed By Fluconazole In Patients With Candidemia, A Serious Fungus Infection Of The Blood.

Candidiasis
Bristol-Myers Squibb

Completed

Drug Interaction - Oral Contraceptive

HIV Infections

United States
Turku University Hospital

Completed

Effect of Itraconazole and Ticlopidine on the Pharmacokinetics and Pharmacodynamics of Oral Tramadol

Pharmacokinetics | Pharmacodynamics

Finland
Abbott

Completed

Recovery Time in Children With Lower Respiratory Tract Infections Treated With Klacid® Granules for Oral Suspension.

Lower Respiratory Tract Infection

Thailand
Bristol-Myers Squibb

Completed

Atazanavir and Ritonavir (ATV/RTV) and an Oral Contraceptive in Healthy Females

HIV Infections

United States
Pfizer
National Institute of Allergy and Infectious Diseases (NIAID)

Completed

Comparison of Fluconazole and Amphotericin B in the Treatment of Brain Infections in Patients With AIDS

HIV Infections | Meningitis, Cryptococcal

United States
National Institute of Allergy and Infectious Diseases...

Completed

Multi-center Comparison of Fluconazole (UK-49,858) and Amphotericin B as Treatment for Acute Cryptococcal Meningitis

HIV Infections | Meningitis, Cryptococcal

United States
Pfizer

Completed

Study Of The Pharmacokinetics And Safety Of Voriconazole In Children 2 To 11 Years Old Who Are At High Risk For Systemic Fungal Infection

Candidemia | Candidiasis

United States
Samsung Medical Center
Janssen, LP

Terminated

Evaluation of Antifungal Prophylaxis on Graft-versus-host Disease (GVHD) Patients (ITRAG)

Graft vs Host Disease

Korea, Republic of
Pfizer

Completed

This Is An Open-Label, Non-Comparative Study Designed To Evaluate A Short Course Of IV Anidulafungin, Followed Optionally By Oral Voriconazole, For The Treatment Of Candidemia And Invasive Candidiasis

Candidemia | Invasive Candidiasis

Panama, Brazil, Mexico, Chile, Colombia
National Institute of Allergy and Infectious Diseases...

Completed

A Multicenter, Prospective, Randomized, Double-Blind Clinical Trial Comparing Itraconazole Oral Solution in Cyclodextrin to Placebo in the Treatment of Aspergilloma

Aspergillosis | Lung Diseases, Fungal

United States
Guangzhou General Hospital of Guangzhou Military...
First Affiliated Hospital, Sun Yat-Sen University; Nanfang Hospital of Southern... and other collaborators

Unknown

Long-term Versus Short-term Sequential Therapy (Intravenous Itraconazole Followed by Oral Solution) of Itraconazole as Primary Prophylaxis in Patients Undergoing Allogeneic Stem Cell Transplantation

Hematological Diseases | Allogeneic Stem Cell Transplantation

China
Pfizer

Completed

A Pharmacokinetic And Safety Study Of Voriconazole In Healthy Male And Female Adults

Healthy Volunteers

Belgium
Facultad Nacional de Salud Publica
Universidad de Antioquia

Completed

Comparison of Moxifloxacin With Ciprofloxacin/Metronidazole on Patients With Chronic Periodontitis

Chronic Periodontitis

Colombia
Axcan Pharma
AAIPharma; Mayo Clinical Services; City Hospital Laboratory Birmingham

Completed

An Open-Label Study to Evaluate the Intraduodenal Delivery of Enzymes From Administration of VIOKASE16 in Exocrine Pancreatic Insufficiency (EPI)

Exocrine Pancreatic Insufficiency

United States
Natividad Medical Center

Completed

A Prospective Trial of Nasal Mupirocin, Hexachlorophene Body Wash, and Systemic Antibiotics for Prevention of Recurrent Methicillin Resistant Staphylococcus Aureus Infections

Methicillin Resistant Staphylococcus Aureus Skin Infections
Abbott

Completed

A Phase III Study Comparing Two Different Anti-HIV Drug Combinations in HIV-Positive Patients Without Previous Anti-HIV Drug Therapy

HIV Infections

United States, Canada, Puerto Rico, Switzerland, France, Germany, United Kingdom, Australia, Brazil, Austria, Denmark, Poland, South Africa, Spain
Santen Inc.
Vistakon Pharmaceuticals

Completed

Ocular Tissue Levels of 1.5% Levofloxacin Ophthalmic Solution Compared to an Active Comparator

Cataract

United States
Santen Inc.

Completed

Ocular Availability in Human Tears After Topical Administration of 1.5% Levofloxacin Compared to Active Comparators

Healthy

United States
Ranbaxy Laboratories Limited

Completed

Bioequivalence Study of Clarithromycin 250 mg/5 mL Powder for Oral Suspension Under Fasting Conditions

Healthy

India

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