Search clinical trials for: Pharmacologic Actions

Total 96250 results

Pfizer

Not yet recruiting

A Study to Learn About the Study Medicine PF-07934040 When Given Alone or With Other Anti-cancer Therapies in People With Advanced Solid Tumors That Have a Genetic Mutation.

Carcinoma, Non-Small-Cell Lung | Colorectal Neoplasms | Carcinoma, Pancreatic Ductal

Puerto Rico
Universitas Diponegoro
Dr. Kariadi General Hospital Medical Center

Recruiting

Biomarkers & Infection After Prophylactic Antibiotic in Cardiac Implantable Electronic Device Implantation (BI-PACED)

Heart Block | Biomarkers | Antibiotic Prophylaxis | CIED Related Infection | CIED-related Infections

Indonesia
Shandong University
Chinese PLA General Hospital

Not yet recruiting

Observational Study on the Sensitivity of Neoadjuvant Immunotherapy in Early Triple-Negative Breast Cancer

Triple Negative Breast Cancer | Sensitivity | Neoadjuvant Immunotherapy
Sichuan Kelun Pharmaceutical Research Institute...

Recruiting

A Study of SKB264 in Combination With Pembrolizumab Versus Pembrolizumab in Patients With Locally Advanced or Metastatic Non-Small Cell Lung Cancer

Non-Small Cell Lung Cancer

China
D. Bradley Welling, MD, PhD
Nobelpharma

Not yet recruiting

In-office Repair of Chronic Tympanic Membrane Perforations

Chronic Tympanic Membrane Perforation

United States
University of Milan
Kolfarma s.r.l. - Italy; Fondazione Telethon

Recruiting

Targeting the Gut to Improve Seizure Control in CDKL5 Deficiency Disorder (CDD) (NUTRIENT)

CDKL5

Italy
AstraZeneca

Not yet recruiting

Volrustomig Priming Regimens Exploratory Phase II Platform Study (eVOLVE-01)

Non-small Cell Lung Cancer
Ohio State University Comprehensive Cancer Center

Recruiting

Manipulating E-Cigarette Nicotine to Promote Public Health

Tobacco-Related Carcinoma

United States
Sichuan Baili Pharmaceutical Co., Ltd.
Baili-Bio (Chengdu) Pharmaceutical Co., Ltd.

Not yet recruiting

A Study of BL-M07D1, BL-M07D1+Pertuzumab and BL-M07D1+Pertuzumab+Docetaxel in Patients With Unresectable Locally Advanced or Metastatic HER2-positive Breast Cancer

HER2-positive Breast Cancer

China
Huai'an First People's Hospital
The Affiliated Hospital of Xuzhou Medical University; The First People's Hospital... and other collaborators

Recruiting

A Clinical Study Evaluating the Safety and Efficacy of ZRMT Regimen in the Treatment of PCNSL

Primary Central Nervous System Lymphoma

China
The University of Texas Health Science Center at...
Baptist Health Foundation of San Antonio

Recruiting

Prevention of Progression of Prediabetes, Obesity and CV Risk (Pre-DM)

Cardiovascular Diseases | Weight, Body | Pre-Diabetes

United States
Merck Sharp & Dohme LLC

Not yet recruiting

Substudy 06D: Combination Therapies in Second Line (2L) Gastroesophageal Adenocarcinoma (MK-3475-06D/Keymaker-U06)

Esophageal Cancer | Esophageal Neoplasms | Gastroesophageal Adenocarcinoma | Gastroesophageal Junction
Sichuan University

Not yet recruiting

Low-dose Radiation Combined With Neoadjuvant Immunochemotherapy for Esophageal Squamous Cell Carcinoma

Esophageal Squamous Cell Carcinoma
Dr. George Luciuk

Recruiting

Effects of Inhaled Epinephrine on Systemic Allergic Reactions During Allergy Testing Immunotherapy or Oral Challenges

Hypersensitivity | Anaphylaxis

Canada
Uppsala University
Sahlgrenska University Hospital, Sweden; University Hospital, Umeå; Uppsala University... and other collaborators

Not yet recruiting

The Case of "Triple" Versus "Double" Therapy for Patients With High Volume Metastatic Hormone Sensitive Prostate Cancer (Lead4Care)

Prostate Cancer

Sweden
Mongi Slim Hospital

Recruiting

Contribution of Ondansetron to Preventing Post-Dural Puncture Headaches Following Spinal Anesthesia (OPDPH)

Post-Dural Puncture Headache

Tunisia
The First Hospital of Jilin University

Not yet recruiting

Adebrelimab Plus Chemotherapy, Bevacizumab and Fluzoparib in Platinum-Sensitive Relapsed Ovarian Cancer

Platinum-sensitive Relapsed Ovarian Cancer
Qilu Pharmaceutical Co., Ltd.

Not yet recruiting

Study of QLS31905 and/or QL1706 Combination With Chemotherapy in the Advanced Malignant Solid Tumors

Advanced Solid Tumor

China
Institut National de la Santé Et de la Recherche...

Recruiting

The Role of Peripheral Afferents in Modulating Post-stroke Central Pain (APEDOC)

Stroke

France
Chang Gung Memorial Hospital

Not yet recruiting

Magnesium Sulfate Combined With Intraarticular Cocktail Injection for Analgesia After Simultaneous Bilateral Total Knee Arthroplasty

Osteoarthritis, Knee
Institute of Hematology & Blood Diseases Hospital...

Recruiting

VMAC+DLI Treatment of Patients With Relapse of AML After Allo-HSCT (VMAC+DLI)

Relapse Acute Myeloid Leukemia

China
KaliVir Immunotherapeutics

Not yet recruiting

A Study of VET3-TGI in Patients With Solid Tumors (STEALTH-001)

Kidney Cancer | Renal Cell Carcinoma | Cervical Cancer | Mesothelioma | Non-small Cell Lung Cancer | Head and Neck Squamous Cell Carcinoma | Solid Tumor, Adult | Microsatellite Stable Colorectal Cancer | Melanoma Stage IV | Merkel Cell Carcinoma of Skin
University of Colorado, Denver
National Institute on Alcohol Abuse and Alcoholism (NIAAA); Colorado State...

Not yet recruiting

Effects of THC on Alcohol Consumption and Neural Correlates of Reward

Cannabis Use Disorder
University of Hamburg-Eppendorf

Not yet recruiting

Model-informed Precision Dosing for Linezolid (LINEMAP)

Gram-Positive Bacterial Infections
Washington University School of Medicine

Not yet recruiting

Propranolol for the Treatment of Kaposi Sarcoma in Adults

Kaposi Sarcoma

United States
Revolution Medicines, Inc.

Recruiting

Study of RAS(ON) Inhibitors in Patients With Gastrointestinal Solid Tumors

Colorectal Cancer | Pancreatic Ductal Adenocarcinoma | Gastrointestinal Cancer | CRC | Metastatic Pancreatic Ductal Adenocarcinoma | PDAC

United States
M.D. Anderson Cancer Center
Rigel Pharmaceuticals,Inc.

Not yet recruiting

Phase 1b/2 Study of Decitabine and Venetoclax in Combination With the Targeted Mutant IDH1 Inhibitor Olutasidenib

Mutant IDH1 Inhibitor Olutasidenib

United States
M.D. Anderson Cancer Center
Qurient Co., Ltd.

Not yet recruiting

Phase I Study of Q702 With Azacitidine and Venetoclax for Relapsed or Refractory Acute Myeloid Leukemia

Acute Myeloid Leukemia

United States
CHU de Reims

Not yet recruiting

Evaluation of the Efficacy of the Addition of Magnesium Sulfate to Morphine on the Occurrence of Acute Urinary Retention Following Epidural Anesthesia for Cesarean Section. (EPIMAG)

Urinary Retention

France
Craig Hospital
University of Colorado, Boulder

Recruiting

Role of Endothelial Function in SCI CVD Risk

Cardiovascular Diseases | Endothelial Dysfunction | Spinal Cord Injuries

United States
Alcon Research

Not yet recruiting

A Double-Masked Comparison of FID 123320 Ophthalmic Solution to Vehicle for the Reduction of Ocular Redness

Ocular Redness

United States
Mayo Clinic

Not yet recruiting

Deucravacitinib (BMS-986165) for Pityriasis Rubra Pilaris

Pityriasis Rubra Pilaris

United States
Rigshospitalet, Denmark

Not yet recruiting

Cocaine, Lidocaine/Xylometazoline and Saline for Nasal Analgesia

Analgesia
Columbia University
University of Southern California; Abdul Latif Jameel Poverty Action Lab; Bowdoin... and other collaborators

Not yet recruiting

E-mail Nudges for Prescribing Risky Drugs

Opioid Prescribing | Prescription Drug Misuse

United States
Peking University

Recruiting

Real-world Study to Evaluate the Efficacy and Safety of Liposome Irinotecan

Colorectal Cancer | Solid Tumor

China
University of Sydney
Woke Pharmaceuticals

Not yet recruiting

Psilocybin-assisted Therapy for Alcohol Use Disorder

Depression | Alcohol Dependence | Anxiety | Alcohol Use Disorder
Assistance Publique - Hôpitaux de Paris

Not yet recruiting

Efficacy and Safety of Bezafibrate 400 mg and Bezafibrate 200 mg as Adjunctive Treatments in Patients With Primary Biliary Cholangitis and Non-optimal Biochemical Response to Ursodeoxycholic Acid Therapy (BEZURSO 2)

BPC | Non Optimal Response to UDCA

France
Regeneron Pharmaceuticals

Not yet recruiting

Assessment of Gastrointestinal Blood Loss After Receiving Aspirin or Aspirin Plus Rivaroxaban, or Aspirin Plus REGN9933, or Aspirin Plus REGN7508 in Healthy Adult Participants

Healthy Volunteers
Mayo Clinic

Not yet recruiting

An Investigational Scan (Ga-68 PSMA-11 PET/CT) for Detection of Disease Recurrence or Progression in Patients With Glioma

WHO Grade 3 Glioma | WHO Grade 2 Glioma | WHO Grade 4 Glioma

United States
Ain Shams University

Recruiting

Clinical Outcome of Vinpocetine in Diabetic Nephropathy

Diabetic Kidney Disease | Diabetic Nephropathies

Egypt
City of Hope Medical Center
National Cancer Institute (NCI)

Recruiting

Vemurafenib and Cobimetinib for the Treatment of Patients With High Risk Differentiated Thyroid Carcinoma With BRAFV600E Mutation

Thyroid Gland Follicular Carcinoma | Thyroid Gland Papillary Carcinoma | Thyroid Gland Oncocytic Carcinoma

United States
University of California, San Francisco
Johns Hopkins University

Not yet recruiting

Program for Rifampicin-Resistant Disease With Stratified Medicine for Tuberculosis (PRISM-TB)

Tuberculosis, Pulmonary | Tuberculosis, Multidrug-Resistant | Tuberculosis, MDR

Peru, Vietnam, Moldova, Republic of, Mongolia, Pakistan, Philippines, South Africa
Xijing Hospital

Recruiting

Preoperative Adjuvant SOX Plus PL-1 Antibody and FLOT Plus PD-1 Antibody for Locally Advanced dMMR Gastric Cancer

Gastric Cancer | Chemotherapeutic Toxicity | Immune-related Adverse Event

China
University of Illinois at Chicago

Recruiting

BRE-10: Biomarker Optimization of Neoadjuvant Therapy in Breast Cancer (BRE-10)

Breast Cancer | HER2-positive Breast Cancer

United States
Applied Science & Performance Institute

Recruiting

Acute Effects of PLT Health Solutions zümXR Extended-Release Caffeine

Cognitive Change | Mood | Caffeine | Mood Change

United States
Hospital San Juan de Dios del Aljarafe de Sevilla

Not yet recruiting

Management of Chronic Non-Cancer Pain With Non-Pharmacological Therapies

Quality of Life | Chronic Pain Syndrome | Patient Empowerment | Sensitization, Central

Spain
Ottawa Hospital Research Institute

Not yet recruiting

Colchicine to Quench the Inflammatory Response After Deep Vein Thrombosis (The Conquer-DVT Pilot Trial)

Venous Thromboembolism

Canada
Institut für Klinische Krebsforschung IKF GmbH...
AstraZeneca; Universitätsklinikum Köln, Germany; Universitätsklinikum Düsseldorf...

Not yet recruiting

Durvalumab + Intraductal Radiofrequency Ablation (ID-RFA) in Extrahepatic Cholangiocarcinoma

Extrahepatic Cholangiocarcinoma | Unresectable Perihilar or Ductal CCA

Germany
Fondazione Italiana Linfomi - ETS

Not yet recruiting

Retrospective-prospective Study to Evaluate Treatment Management and Outcomes of Patients With Waldenström's Macroglobulinemia (WM) Treated in Italy According to the Zanubrutinib (Brukinsa®) Compassionate Use Program (CUP) and in Common Practice Following Commercial Approval.

Waldenström's Macroglobulinemia (WM)

Italy
Ruijin Hospital

Not yet recruiting

Efficacy of Pola-RCHP-X vs Pola-RCHP in Untreated DLBCL

Diffuse Large B-Cell Lymphoma

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