Search clinical trials for: Phase II study

Total 145390 results

M.D. Anderson Cancer Center
Astex Pharmaceuticals, Inc.; Syndax Pharmaceuticals

Recruiting

A Phase I-II Study Investigating the All Oral Combination of the Menin Inhibitor SNDX-5613 With Decitabine/Cedazuridine (ASTX727) and Venetoclax in Acute Myeloid Leukemia (SAVE)

Acute Myeloid Leukemia

United States
Tianjin Medical University Cancer Institute and...
Chongqing University Cancer Hospital; Xiangya Hospital of Central South University and other collaborators

Not yet recruiting

An Open-label, Single-arm, Multicenter Phase II Clinical Study： Evaluating RC48-ADC Combined With Triplizumab in the Neoadjuvant Treatment of Her2-positive Muscle-invasive Bladder Cancer

Neoadjuvant Treatment of Her2-positive Muscle-invasive Bladder Cance
M.D. Anderson Cancer Center

Recruiting

A Phase II Study of the Combination of Azacitidine and Pembrolizumab for Patients Relapsed/Refractory Hodgkin's Lymphoma

Hodgkin's Lymphoma

United States
Jiangsu HengRui Medicine Co., Ltd.

Recruiting

A Phase Ib/II Study of SHR-A1811 Injection in Breast Cancer

Breast Cancer

China
Rigshospitalet, Denmark
Odense University Hospital; Aarhus University Hospital; University of Copenhagen and other collaborators

Recruiting

A Multicenter Phase II Study of Stereotactic Radiotherapy for Centrally Located Lung Tumors (STRICT-LUNG STUDY) and Ultra-centrally Located Lung Tumors (STAR-LUNG STUDY). (STRICTSTARLUNG)

Lung Cancer | Radiotherapy Side Effect | Metastases to Lung

Denmark
Shanghai Junshi Bioscience Co., Ltd.

Not yet recruiting

Toripalimab Plus Lenvatinib and Gemcitabine-based Chemotherapy in 1L Treatment of Advanced ICC: a Phase III Study

Intrahepatic Cholangiocarcinoma

China
Allegheny Singer Research Institute (also known...
Elekta Limited

Recruiting

A Phase II Study of Pre-Op SRS Followed by Surgical Resection for Brain Metastases

Brain Metastases, Adult

United States
Chipscreen Biosciences, Ltd.

Recruiting

A Phase II Study of Chiauranib in Combine With Capecitabine in TNBC

Triple-negative Breast Cancer

China
M.D. Anderson Cancer Center

Recruiting

Phase II Study of Salvage Radiation Treatment After B-cell Maturation Antigen Chimeric Antigen Receptor T-cell Therapy for Relapsed Refractory Multiple Myeloma

Multiple Myeloma | Plasma Cell Neoplasm | Malignant Plasma Cell Neoplasm

United States
Chinese PLA General Hospital

Recruiting

An Open-label, Phase I/II Study of PLENA Regimen in Patients With Unresectable Pancreatic Cancer or BTC

Pancreatic Cancer | Biliary Tract Cancer

China
NRG Oncology
National Cancer Institute (NCI)

Recruiting

Testing the Addition of Stereotactic Radiation Therapy With Immune Therapy for the Treatment of Patients With Unresectable or Metastatic Renal Cell Cancer, SAMURAI Study (SAMURAI)

Metastatic Renal Cell Carcinoma | Stage III Renal Cell Cancer AJCC v8 | Stage IV Renal Cell Cancer AJCC v8 | Unresectable Renal Cell Carcinoma

United States
Peking University People's Hospital
Zhonghao Pharmaceutical

Recruiting

Phase III Clinical Study of Benvitimod Cream in the Treatment of Mild to Moderate Atopic Dermatitis

Atopic Dermatitis

China
Zhejiang Cancer Hospital

Not yet recruiting

Phase II Clinical Study of Camrelizumab Combined With Chemotherapy or Anlotinib in Advanced Esophageal Squamous Cell Cancer

Stage IV Esophagus Squamous Cell Carcinoma

China
Fujian Cancer Hospital

Recruiting

Phase I/II Study of the Combination of Irinotecan and POF (POFI) and Tislelizumab

Gastric Cancer Stage IV

China
Akeso

Recruiting

A Phase II Study of AK104 Plus Lenvatinib and TACE in HCC

Unresectable, Non-metastatic Hepatocellular Carcinoma

China
Zhuhai Yufan Biotechnologies Co., Ltd

Recruiting

A Phase I/II Study to Evaluate the Safety, Pharmacokinetics and Efficacy of PRJ1-3024 in Subjects With Advanced Solid Tumors

Advanced Solid Tumor | Advanced Solid Malignancies

China
Shandong New Time Pharmaceutical Co., LTD

Not yet recruiting

A Phase III Clinical Study of Minodronate Tablets in Postmenopausal Women With Osteoporosis

Osteoporosis

China
Enliven Therapeutics

Recruiting

A Phase 1a/1b Study of ELVN-001 for the Treatment Chronic Myeloid Leukemia (CML)

Chronic Myeloid Leukemia

United States, Spain, France, Germany, Korea, Republic of, Australia, Canada
Instituto de Investigación Hospital Universitario...

Recruiting

"Phase I / II Study on Infusion of Natural Killer Cells After Haploidentical Transplantation in Pediatric Patients" (PHINK)

High-risk Leukemias

Spain
Fondazione Italiana Linfomi - ETS
Roche Pharma AG

Recruiting

Study of Atezolizumab Plus BEGEV Regimen in Relapsed or Refractory Hodgkin's Lymphoma Patients (FIL_A-BEGEV)

Relapsed or Refractory Hodgkin's Lymphoma

Italy
The First Affiliated Hospital of Xiamen University

Recruiting

A Single-Arm Phase II Clinical Study of Pemigatinib in the Treatment of Advanced Non-Small Cell Lung Cancer Patients With FGFR Alterations Who Have Failed Standard Therapy

Advanced Non-Small Cell Lung Cancer

China
M.D. Anderson Cancer Center

Recruiting

A Phase II Study of Vibecotamab (XmAb14045) for MRD- Positive AML and MDS After Hypomethylating Agent Failure

AML | MDS

United States
Kiora Pharmaceuticals, Inc.

Recruiting

A Phase I/II Dose-escalating Study of the Safety, Tolerability and Efficacy of KIO-301 Administered Intravitreally to Patients With Retinitis Pigmentosa and Choroideremia (ABACUS) (ABACUS)

Retinitis Pigmentosa | Choroideremia

Australia
Shouyao Holdings (Beijing) Co. LTD

Recruiting

Phase I/II Study of SY-5007, a RET Inhibitor, in Patients With RET-altered Advanced Solid Tumor

Non-Small Cell Lung Cancer | Solid Tumor | Medullary Thyroid Cancer

China
Shanghai YingLi Pharmaceutical Co. Ltd.

Recruiting

A Phase II Study of Linperlisib (YY-20394) in Patients With Relapsed or Refractory Peripheral T/NK Cell Lymphoma

Peripheral T/NK Cell Lymphoma (R/R PTCL)

United States
M.D. Anderson Cancer Center

Recruiting

A Phase II Study of the Combination of Ponatinib With Mini-hyper CVD Chemotherapy and Venetoclax in Patients With Relapsed or Refractory T-cell Acute Lymphoblastic Leukemia

Leukemia | Acute Lymphoblastic Leukemia

United States
Qingdao Central Hospital

Recruiting

Phase II Study of Afatinib Plus Bevacizumab in the Treatment Epidermal Growth Factor Receptor (EGFR) Exon G719X, S768I, and L861Q Mutation Metastatic Non-Small Cell Lung Cancer

PFS

China
Elizabeth Dudnik

Recruiting

Durvalumab (MEDI4736) Plus Platinum-based Chemotherapy in Advanced LCNEC: a Pilot Phase II Study

Patients With Advanced Treatment Naive LCNEC

Israel
Huihan Wang

Recruiting

Dual Growth Factor (rhTPO + G-CSF) and Chemotherapy Combination Regimen for Elderly Patients With Acute Myeloid Leukemia: A Phase II Single-Arm Multicenter Study

Acute Myeloid Leukemia

China
Shouyao Holdings (Beijing) Co. LTD

Recruiting

Phase I/II Study of SY-3505 in Patients With ALK-positive Advanced Non-small Cell Lung Cancer

Non-small Cell Lung Cancer

China
Dr. Soetomo General Hospital
Universitas Airlangga

Recruiting

Clinical Trial of Probiotic Supplementation in Psoriasis Vulgaris

Psoriasis Vulgaris

Indonesia
Lipidor AB

Recruiting

A Phase III Study in Subjects With Mild to Moderate Psoriasis. (AKVANO-AKP02)

Mild to Moderate Psoriasis

India
Li Zhang, MD

Recruiting

An Open Label, Multicenter Phase 2 Study of Durvalumab (MEDI4736) + Olaparib as Maintenance Therapy in Chinese

Small Cell Lung Cancer | Lung Cancer | Durvalumab

China
Akeso
Peking University Cancer Hospital & Institute

Recruiting

A Phase III Study to Evaluate the Efficacy and Safety of Penpulimab in the Relapsed and Refractory Classical Hodgkin's Lymphoma

Hodgkin Disease Lymphoma

China
The First Affiliated Hospital of Zhengzhou University

Not yet recruiting

A Phase II Clinical Study of Fruquintinib Combined With RC48 in the Treatment of Previously Treated HER2-positive Locally Advanced or Metastatic Gastric or Gastroesophageal Junction (G/GEJ) Cancer

Gastric Cancer

China
Shanghai Henlius Biotech

Not yet recruiting

Phase II Clinical Study to Evaluate the Efficacy and Safety of HLX07+HLX10 +mFOLFOX6 or HLX07 Monotherapy in Patients With mCRC

CRC
Sun Yat-sen University

Recruiting

A Phase II Clinical Study of Surufatinib Combined With Sintilimab in the Treatment of Advanced Gastric Cancer

Gastric Adenocarcinoma

China
Akeso

Recruiting

A Phase Ib/II Study of AK104 and AK117 in Combination With or Without Chemotherapy in Advanced Malignant Tumors

Advanced Malignant Tumors

China
Greenwich LifeSciences, Inc.

Recruiting

Phase 3 Study to Evaluate the Efficacy and Safety of HER2/Neu Peptide GLSI-100 (GP2 + GM-CSF) in HER2/Neu Positive Subjects (FLAMINGO-01)

Breast Cancer

France, United States, Spain, Germany, Italy, Poland
The First Affiliated Hospital of Zhengzhou University

Not yet recruiting

A Phase II Study of Tislelizumab as Adjuvant Therapy for Patients With Stage Ⅱ and Stage Ⅲ Colon Cancer and dMMR/MSI.

Colon Cancer
Akeso

Recruiting

A Phase Ib/II Study of AK112 in Combination With AK117 in Advanced Malignant Tumors

Advanced Malignant Tumors

China
Shanghai Henlius Biotech

Recruiting

A Phase II Clinical Study to Evaluate the Efficacy and Safety of HLX07 Combination Therapy or Monotherapy in Patients With Advanced ESCC

ESCC or Esophageal Adenosquamous Carcinoma

China
Code Pharma

Recruiting

Phase IIa Randomized Placebo Controlled Clinical Study of Codivir in Hospitalized Patients With Moderate COVID-19

COVID-19

South Africa
Shenyang Sunshine Pharmaceutical Co., LTD.

Recruiting

Phase III Clinical Study of Recombinant Erythropoiesis Stimulating Protein Injection (rESP) in the Treatment of Anemia in Hemodialysis Patients With Chronic Renal Failure

Hemodialysis | Kidney Failure, Chronic

China
Assistance Publique - Hôpitaux de Paris

Recruiting

Prospective Evaluation of the Prognostic Impact of Measurable Residual Disease (MRD) Within a Phase III Study Comparing a Fixed Duration Therapy Versus Continuous Therapy With Daratumumab, Lenalidomide, and Dexamethasone for Relapsed Multiple Myeloma Requiring a First Salvage Treatment. (MRD-CONFIRM)

Multiple Myeloma

France
Fuzhou General Hospital

Recruiting

Peginterferon Alpha-2b Therapy in Chronic Hepatitis Patients With Normal ALT Level and Low Viremia

Chronic Hepatitis B Patients With a Normal ALT Level and Low Viremia

China
University of Aarhus
Odense University Hospital; Aarhus University Hospital; Rigshospitalet, Denmark; University of Leeds and other collaborators

Recruiting

A National Phase II Study of Proton Therapy in Hepatocellular Carcinoma

Hepatocellular Carcinoma

Denmark
Wuhan Union Hospital, China

Recruiting

A Single-Arm Phase II Exploratory Clinical Study of Pemigatinib in the Treatment of Advanced Gastric and Colorectal Cancer Patients With FGFR Alterations Who Have Failed Standard Therapy

Gastric and Colorectal Cancer

China
Academic and Community Cancer Research United
National Cancer Institute (NCI)

Recruiting

A Phase II Study of Nivolumab + Ipilimumab in Advanced HCC Patients Who Have Progressed on First Line Atezolizumab + Bevacizumab

Unresectable Hepatocellular Carcinoma | Stage III Hepatocellular Carcinoma AJCC v8 | Stage IIIA Hepatocellular Carcinoma AJCC v8 | Stage IV Hepatocellular Carcinoma AJCC v8 | Stage IVA Hepatocellular Carcinoma AJCC v8 | Stage IVB Hepatocellular Carcinoma AJCC v8 | BCLC Stage B Hepatocellular Carcinoma and other conditions

United States
Assistance Publique - Hôpitaux de Paris
Pfizer

Recruiting

Hemolysis Related Complications in SCD. A Phase II Study With Voxelotor (HEMOPROVE)

Sickle Cell Disease

France

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