Search clinical trials for: healthy participants

Total 35778 results

Eli Lilly and Company

Completed

A Study of Carbon-14-Labelled [14C] LY3473329 in Healthy Male Participants

Healthy

United Kingdom
Hoffmann-La Roche

Completed

A Study Evaluating the Safety, Efficacy and Pharmacokinetics of Venetoclax in Combination With Polatuzumab Vedotin Plus Rituximab (R) and Cyclophosphamide, Doxorubicin, Prednisone (CHP) in Participants With Untreated BCL-2 Immunohistochemistry (IHC)-Positive Diffuse Large B-Cell Lymphoma (DLBCL)

Lymphoma, Large B-Cell, Diffuse

United States, France, Spain, Italy
Visterra, Inc.

Active, not recruiting

A Study to Investigate the Safety, Pharmacokinetics, and Pharmacodynamics of VIS954 in Healthy Adult Participants

Healthy Volunteers

United States
Novo Nordisk A/S

Completed

A Research Study Looking at New Protein-based Tablets in Healthy Male Participants

Type 2 Diabetes | Healthy Volunteers | High Blood Cholesterol Levels

Germany, Canada
Eli Lilly and Company

Active, not recruiting

A Drug-Drug Interaction Study of Orforglipron (LY3502970) in Healthy Overweight and Obese Participants

Healthy | Overweight | Obese

United States
Novartis Pharmaceuticals

Completed

A Study to Investigate the Pharmacokinetics and Safety of Remibrutinib in Participants With Hepatic Impairment Compared With Matched Healthy Participants

Hepatic Impairment

Hungary
AstraZeneca

Active, not recruiting

A Study to Investigate Relative Bioavailability of Two Different Dosage Forms for Tozorakimab Via Subcutaneous Administration in Healthy Volunteers

Healthy Participants

Germany
Janssen Research & Development, LLC

Suspended

A Study of JNJ-64281802 Against Dengue Serotype 1 Infection in a Dengue Human Challenge Model in Healthy Adult Participants

Healthy

United States, United Kingdom
AbbVie
Gedeon Richter Plc.

Active, not recruiting

Study to Assess Adverse Events and How ABBV-932 Oral Capsules Moves Through the Body of Healthy Adult Participants

Healthy Participants | Generalized Anxiety Disorder (GAD)

United States
Eli Lilly and Company

Active, not recruiting

A Study of Donanemab (LY3002813) in Participants With Early Alzheimer's Disease (TRAILBLAZER-ALZ 2)

Alzheimer Disease

United States, Canada, Australia, Japan, Poland, Puerto Rico, Czechia, Netherlands, United Kingdom
Nuvamid SA
Medpace, Inc.; Anapharm; LGD

Completed

Study of the Safety, Tolerability, and Pharmacokinetics of NUV001 Administered Orally to Healthy Adult Participants

Healthy Volunteers

United States
Hoffmann-La Roche

Active, not recruiting

A Study to Evaluate Single Subcutaneous Doses of NXT007 Among Injection Sites Abdomen, Upper Arm, and Thigh in Healthy Male Participants

Healthy Male Participants

New Zealand
Amgen

Active, not recruiting

A Study to Assess Bioavailability of Rocatinlimab (AMG 451) Vial and Prefilled Syringe in Healthy Participants

Atopic Dermatitis

United States, United Kingdom
Arcus Biosciences, Inc.
Gilead Sciences

Completed

A Study Investigating the Safety, Absorption, and Elimination of Radioactively Labeled Etrumadenant, a New Compound in the Treatment of Cancer

Healthy Participants

Netherlands
UCB Biopharma SRL

Active, not recruiting

A Study to Test the Safety, Pharmacokinetics, and Efficacy of UCB9741 in Healthy Study Participants and in Study Participants With Atopic Dermatitis

Atopic Dermatitis

Bulgaria, Germany, Netherlands, United Kingdom
Arcus Biosciences, Inc.

Completed

A Relative Bioavailability Study and Food Effect Study of AB521 in Healthy Adult Volunteers (ARC-28)

Healthy Participants

United States
Arcus Biosciences, Inc.

Completed

A Drug-Drug Interaction Study to Evaluate the Effect of Itraconazole on the Pharmacokinetic Profile of Etrumadenant in Healthy Adult Participants

Healthy Participants

United States
Arcus Biosciences, Inc.

Completed

Study to Investigate the Safety, Tolerability, and Pharmacokinetic Profile With Oral AB521 in Healthy Volunteers (ARC-14)

Healthy Participants

Netherlands
Loxo Oncology, Inc.
Eli Lilly and Company

Completed

A Drug Drug Interaction (DDI) Study of Selpercatinib and Dabigatran in Healthy Participants

Healthy

United States
Sanofi Pasteur, a Sanofi Company

Completed

Study on a MenACYW Conjugate Vaccine Administered as a Single Dose in Participants Aged 12 Months and Older in Vietnam

Healthy Volunteers | Meningococcal Infection

Vietnam
Arcus Biosciences, Inc.
Gilead Sciences

Completed

A Study to Evaluate Pharmacokinetics (PK) of Etrumadenant Tablet and Capsule Formulations in Healthy Adult Participants

Healthy Participants

United States
Yale University
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); Merck...

Completed

The Effect of Glucagon on Rates of Hepatic Mitochondrial Oxidation in Man Assessed by PINTA

Healthy Participants

United States
Janssen Research & Development, LLC

Completed

A Safety and Tolerability Study of JNJ-72537634 in Healthy Participants

Healthy

Belgium
Bristol-Myers Squibb

Completed

A Study to Evaluate the Safety, Tolerability, and Drug Levels of Danicamtiv in Healthy Japanese and Caucasian Participants

Healthy Volunteers

United States
Gilead Sciences
The Leukemia and Lymphoma Society

Terminated

Trial of Magrolimab (Hu5F9-G4) in Combination With Rituximab or Rituximab + Chemotherapy in Participants With Relapsed/Refractory B-cell Non-Hodgkin's Lymphoma

Non Hodgkin Lymphoma

United States, Australia, United Kingdom
Biogen

Completed

A Study to Look at How a Single Oral Dose of Carbon-14-Labelled [14C] BIIB091 Moves Through and is Processed by the Body in Healthy Male Participants (Mass Balance)

Healthy Volunteer

United States
Pfizer

Completed

A Study to Compare Two Tablet Forms of Tafamidis in Healthy Participants

Healthy

Belgium
Pfizer
Arvinas Estrogen Receptor, Inc.

Completed

A Study to Learn If the Study Medicine Called Vepdegestrant Changes How the Body Processes the Other Study Medicine Called Midazolam

Healthy Participants

Belgium
Janssen Research & Development, LLC

Active, not recruiting

A Study of a Rilpivirine Extended-Release Suspension in Healthy Participants

Healthy

United States, Netherlands
Syneos Health
Aiolos Bio, Inc.

Active, not recruiting

Study to Evaluate the AIO-001 in Healthy Participants

Respiratory Disease

Australia
Actelion

Completed

A Study of Fixed Dose Combination of Macitentan/Tadalafil (10 mg/20 mg) Compared to the Reference Free Combination of Macitentan and Tadalafil in Healthy Adult Participants

Healthy

United States
Janssen Research & Development, LLC

Completed

A Study of JNJ-67835989 in Healthy Participants

Healthy

Belgium
Janssen Research & Development, LLC

Active, not recruiting

A Study of JNJ-63733657 in Participants With Early Alzheimer's Disease (Autonomy)

Cognitive Dysfunction | Dementia | Alzheimer Disease

United States, Belgium, France, Japan, United Kingdom, Spain, Canada, Australia, Sweden, Netherlands
Hoffmann-La Roche
Chugai Pharmaceutical

Active, not recruiting

Study to Assess Safety, Efficacy, Pharmacokinetics, and Pharmacodynamics of Crovalimab in Healthy Volunteers and Participants With Paroxysmal Nocturnal Hemoglobinuria (COMPOSER)

Paroxysmal Hemoglobinuria, Nocturnal

France, Korea, Republic of, Italy, Japan, Germany, Hungary, Netherlands
Beijing QL Biopharmaceutical Co.,Ltd
Beijing Hospital

Completed

A SAD Study of ZT002 Injection in Healthy Participants

Type 2 Diabetes Mellitus

China
Genzyme, a Sanofi Company

Completed

A Study of the Safety, Tolerability, and Pharmacokinetics of Orally Administered Venglustat and Itraconazole in Healthy Adult Male Participants

Healthy Volunteers

United States
Merck Sharp & Dohme LLC

Completed

Respiratory Syncytial Virus (RSV) Human Challenge Study of Molnupiravir in Healthy Participants (MK-4482-017)

Respiratory Syncytial Virus

United Kingdom
OrsoBio, Inc

Completed

A Study to Evaluate Single and Multiple Doses of TLC-2716 in Healthy Participants

Healthy Subjects

New Zealand
University of Delaware
American Society for Nutrition Foundation

Completed

First Complementary Foods and the Infant Gastrointestinal Microbiota

Healthy Participants | Infants | Gastrointestinal Microbiota

United States
Hoffmann-La Roche

Completed

Study to Assess the Safety, Pharmacokinetics, and Efficacy of Baloxavir Marboxil in Healthy Pediatric Participants From Birth to < 1 Year With Influenza-Like Symptoms

Influenza

Poland, United States, Costa Rica, Bulgaria, South Africa, Spain, Israel, Finland, Russian Federation
Inmagene LLC

Completed

Study to Evaluate IMG-004 in Healthy Participants

Healthy Participants

United States
Sanofi

Completed

A Study of the Safety, Tolerability, and Bioavailability of Orally Administered Venglustat in Healthy Adult Participants

Healthy Volunteers

United States
AstraZeneca

Completed

A Study to Investigate the Effect on QTcF of Baxdrostat Compared With Placebo, Using Moxifloxacin as a Positive Control, in Healthy Participants

Healthy Participants

Germany
Sanofi

Completed

A Study of the Safety, Tolerability, and Bioequivalence of Orally Administered Venglustat in Healthy Adult Participants

Healthy Volunteers

United States
AstraZeneca

Completed

Assess the Safety, Tolerability and Pharmacokinetics of AZD5055 Following Single and Multiple Ascending Doses in Healthy Participants

Idiopathic Pulmonary Fibrosis

United States
Alexion Pharmaceuticals, Inc.

Completed

Potential Drug Interaction Study Between Vemircopan and Rosuvastatin, Metformin, Levonorgestrel/Ethinyl Estradiol-containing Oral Contraceptives, and Carbamazepine

Healthy Participants

United States
HanAll BioPharma Co., Ltd.
NurrOn Pharmaceuticals, Inc.

Completed

A Study Assessing the Safety of Oral ATH-399A in Healthy Adult Participants

Healthy Volunteers

Canada
University of Aarhus

Enrolling by invitation

Prevention of Hazardous Use of Alcohol With Danish High School Students (Our Choice)

Healthy Participants

Denmark
Agomab Spain S.L.

Completed

Relative Bioavailability and Effect of Food Study With AGMB-129 in Healthy Participants

Healthy Volunteers

Belgium
Pfizer

Completed

A Study to Learn About Effect of Sisunatovir in Healthy Adult Male Participants

Respiratory Syncytial Virus Infections

United States

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