Search clinical trials for: normal subjects

Total 24305 results

Anthera Pharmaceuticals

Terminated

A Study of Varespladib Infusion in Subjects With Sickle Cell Disease. (IMPACTS-2)

Sickle Cell Disease | Vaso-occlusive Crisis

United States
Vanda Pharmaceuticals

Completed

Pharmacokinetics of Tasimelteon in Subjects With Renal Impairment and Matched Control Subjects With Relatively Normal Renal Function

Renal Impairment

United States
Hanmi Pharmaceutical Company Limited

Unknown

A Phase 1b Study of LAPS-Exendin in Subjects of Type 2 Diabetes Mellitus

Diabetes Mellitus

United States
Merck KGaA, Darmstadt, Germany

Completed

Pharmacokinetics in Subjects With Renal Impairment

Renal Impairment

Germany
AVEO Pharmaceuticals, Inc.

Completed

A Single-Dose Study of Tivozanib in Subjects With Hepatic Impairment and Normal Hepatic Function

Hepatic Impairment

United States
Mannkind Corporation

Completed

Single Dose, Single Administration Study of Technosphere Inhalation Powder in Diabetic Subjects With Mild or Moderate Kidney Disease Compared to Diabetic Subjects With Normal Kidney Function

Diabetes Mellitus | Mild Nephropathy | Moderate Nephropathy

United States
University Hospital Tuebingen
Haag-Streit AG

Completed

Age-related Normative Values for the Octopus 900 Perimeter (Norm-Oct900)

Healthy

Germany
PharmAthene, Inc.
National Institute of Allergy and Infectious Diseases (NIAID); National Institutes... and other collaborators

Completed

Dose Escalation Study of Valortim® (MDX-1303) Administered Intravenously (IV) in Healthy, Normal Subjects

Anthrax

United States
Taiwan Liposome Company

Completed

An Bioequivalence Study to Compare Two 2 mg/ml Liposomal Amphotericin B Injections in Healthy Subjects

Normal Healthy Subjects
Sanofi Pasteur, a Sanofi Company

Completed

Study of a Clostridium Difficile Toxoid Vaccine (ACAM-CDIFF™) in Subjects With Clostridium Difficile Infection

Diarrhea | Clostridium Difficile Infection

United Kingdom, United States
Biogen

Completed

BIIB023 (Anti-TWEAK) in Subjects With Rheumatoid Arthritis

Rheumatoid Arthritis

United States, Russian Federation
Astellas Pharma Inc

Completed

A Pharmacokinetic Study of YM178 in Normal Subjects and Those With Mild, Moderate, and Severe Renal Impairment

Renal Impairment

United States
Gilead Sciences

Completed

A Phase 1 Study to Evaluate the Pharmacokinetics of GS-5816 in Subjects With Normal Hepatic Function and Moderate or Severe Hepatic Impairment

Chronic Hepatitis C

United States, Puerto Rico
The University of Hong Kong

Terminated

A Prevalence Study of Obstructive Sleep Apnea in Subjects With Chest Pain, Positive Exercise Treadmill Test and Normal Coronary Angiogram

Obstructive Sleep Apnea | Endothelial Dysfunction | Cardiac Syndrome X

Hong Kong
MetroHealth Medical Center

Completed

Effect of Beta-blocker Therapy on QTc Response in Exercise and Recovery in Normal Subjects

Long QT Syndrome | Cardiac Repolarization
Rempex Pharmaceuticals (a wholly owned subsidiary...

Completed

Safety, Tolerability, Pharmacokinetics of Intravenous RPX7009 in Healthy Adult Subjects

Bacterial Infections | Healthy Volunteers

Australia
Alaunos Therapeutics

Unknown

Effect on QTc, Pharmacokinetics, Safety, and Preliminary Efficacy of Single-agent Palifosfamide-tris in Subjects With Advanced Solid Tumors

Advanced Solid Tumors

United States
Michelle Hernandez, MD
National Institute of Allergy and Infectious Diseases (NIAID)

Completed

Effect of Interleukin-1 Receptor Antagonist on Inhalation of 20,000 EU Clinical Ctr Reference Endotoxin in Normal Volunteers (Kintox)

Healthy Control Subjects

United States
Guangzhou Institute of Respiratory Disease

Completed

Influence of Trigger Threshold on Controlled Twitch Mouth Pressure

Healthy | COPD

China
Universidade Federal de Pernambuco
Coordenação de Aperfeiçoamento de Pessoal de Nível Superior.; Conselho Nacional... and other collaborators

Completed

Radioaerossol Pulmonary Deposition Using Mesh in Normal Subjects

Normal Subjects

Brazil
Orrin M Troum, M.D. and Medical Associates
Bristol-Myers Squibb

Completed

Exploratory Trial to Evaluate Premature Endothelial Dysfunction in Early Rheumatoid Arthritis(RA)Compared to Patients With Established RA, and Normal Subjects

Healthy | Rheumatoid Arthritis | Premature Endothelial Dysfunction

United States
PhaseBio Pharmaceuticals Inc.

Completed

Pharmacokinetic, Safety/Tolerability Study of a Single SC Dose of PB1023 Injection in Subjects With Normal and Impaired Renal Function

Diabetes Mellitus, Type 2

United States
Sanofi

Terminated

Effects of Dronedarone on Atrial Fibrillation Burden in Subjects With Permanent Pacemakers (HESTIA)

Atrial Fibrillation

United States
FHI 360
Bill and Melinda Gates Foundation; Marie Stopes International

Completed

A Prospective Observational Study of the Clinical Performance of Zarin in Madagascar

Long-term and Permanent Contraceptive Methods

Madagascar
Newron Pharmaceuticals SPA

Completed

A Study to Assess the Effect of Hepatic Impairment on Safinamide Pharmacokinetics

Hepatic Impairment

Germany
Avid Radiopharmaceuticals

Completed

Observational Study of Cognitive Outcomes for Subjects Who Have Had Prior PET Amyloid Imaging With Florbetapir F 18 (18F-AV-45)

Mild Cognitive Impairment | Alzheimer's Disease

United States
Keith A. Rodvold
Forest Laboratories

Completed

Pharmacokinetics of Ceftaroline in Normal and Obese Subjects

Drug Safety

United States
Zhongshan Bo Ai Hospital

Completed

The Potential Biochemical Diagnosis Criteria and Therapeutic Effect Indexes: Sex Hormone Binding Globulin Levels and Free Androgen Index in Blood of Patients With Polycystic Ovary Syndrome

The Investigators Collected 534 PCOS Patients as the Case Group,and 580 Infertile Women With Normal Ovulatory Cycle of the Control Group; | At the Same Time, the Investigators Continuedly Collect Cases to October 2012, and Totally Collected 579 Patients With PCOS Altogether; | 534... and other conditions

China
Alnylam Pharmaceuticals

Completed

Trial to Evaluate Safety, Tolerability, and Parmacokinetics of ALN-TTR02 in Healthy Volunteer Subjects

TTR-mediated Amyloidosis

United Kingdom
Mayo Clinic

Completed

Effects of Gastric Antral Botulinum Toxin Injections in Obese Subjects

Obesity

United States
Wockhardt

Completed

Comparative Wockhardt's Glucose Clamp Study-Human Isophane Susp 30IU/ml/70IU/ml With Novolin70/30, in Healthy Subjects

Diabetes Mellitus

United States
University of North Carolina, Chapel Hill
National Institute of Allergy and Infectious Diseases (NIAID)

Completed

A Study of Inhalation of 20,000 EU CCRE in Normal Volunteers Compared to Allergic Asthmatic Individuals (Endomac)

Hypersensitivity | Asthma

United States
Sangamo Therapeutics
Juvenile Diabetes Research Foundation

Completed

Clinical Trial of SB-509 in Subjects With Diabetic Neuropathy

Diabetes Mellitus, Type 2 | Diabetes Mellitus, Type 1 | Diabetic Polyneuropathy

United States, Mexico
Alnylam Pharmaceuticals

Completed

Trial to Evaluate Safety and Tolerability of ALN-PCS02 in Subjects With Elevated LDL-Cholesterol (LDL-C)

Elevated LDL-Cholesterol (LDL-C)

United Kingdom
MedImmune LLC

Completed

A Study to Assess Selected Biomarkers in Subjects Requiring Daily Inhaled Corticosteroids for Persistent Asthma

Asthma

United States, Canada
University Hospital, Basel, Switzerland

Completed

Effects of Melatonin and Oxygen Consumption and Choroidal Blood Flow (MelO2)

Vasospastic Syndrome

Switzerland
Avid Radiopharmaceuticals
General Electric; American College of Radiology Imaging Network

Completed

Ability Of ([18F]-AV-45) PET Scan to Distinguish Alzheimer's Disease Subjects From Cognitively Normal Individuals

Alzheimer's Disease

United States
Revalesio Corporation

Completed

Feasibility Study to Evaluate the Safety of Topically Applied Revera in Subjects With Venous Leg Ulcers

Venous Stasis Ulcers

United States
Sunovion

Completed

Safety and Efficacy of Arformoterol Tartrate Inhalation Solution in Subjects With Chronic Obstructive Pulmonary Disease

Chronic Obstructive Pulmonary Disease | Emphysema | Bronchitis

United States
Siemens Molecular Imaging

Terminated

Exploratory, Phase I,Open Label,Non-randomized Study of [F18]CP-18 PET in Normal and Breast Cancer Subjects

Breast Cancer

United States
Nycomed
NPS Pharma

Completed

Pharmacokinetics of 10 mg Teduglutide in Subjects With Renal Impairment Compared to Healthy Subjects With Normal Renal Function

Renal Impairment

Germany
Cephalon

Completed

A Study to Evaluate the Pharmacokinetics of the Hydrocodone Extended-Release Tablet (CEP-33237) in Subjects With Normal Hepatic Function and Subjects With Moderate Hepatic Impairment

Hepatic Impairment

United States
Cephalon

Completed

A Study to Assess the Pharmacokinetics of the Hydrocodone Extended-Release Tablet (CEP-33237) in Subjects With Normal Renal Function and Subjects With Varying Degrees of Renal Impairment

Renal Impairment

United States
Anthera Pharmaceuticals

Terminated

A Study of the Pharmacokinetics and Safety of Varespladib in Subjects With Normal or Impaired Renal Function

Renal Impairment

United States
GlaxoSmithKline

Completed

A Comparison Of Study Drug Blood Levels After One Dose Of GSK189075 In Subjects With Normal And Reduced Kidney Function

Diabetes Mellitus, Type 2 | Renal Insufficiency | Type 2 Diabetes Mellitus

United States
Cyberonics, Inc.

Completed

Heart Rate Changes During Normal Activity, Exercise, and Seizures in Subjects With Epilepsy

Epilepsy

United States
Genta Incorporated

Completed

Pharmacokinetic Study of Genasense in Subjects With Normal Renal Function, Mildly Impaired Renal Function, and Moderately Impaired Renal Function

Normal Renal Function | Mildly Impaired Renal Function | Moderately Impaired Renal Function

United States
Novartis Pharmaceuticals

Completed

Pharmacokinetics of Nilotinib in Subjects With Impaired Hepatic Function and Healthy Subjects With Normal Hepatic Function

Healthy

United States
Sunovion

Completed

To Evaluate the Long-term Safety of (R,R)-Formoterol in Subjects With COPD

Chronic Obstructive Pulmonary Disease | Emphysema | Chronic Bronchitis

United States
Sunovion

Completed

A Safety and Tolerability Study of Arformoterol Tartrate Inhalation Solution in Pediatric Subjects

Asthma

United States

3

Subscribe