Search clinical trials for: older age

Total 199024 results

GlaxoSmithKline

Completed

A Study to Assess the Safety and Immune Response of Quadrivalent Seasonal Influenza Vaccine (Fluarix Tetra) in Participants Aged 65 Years and Older in India

Influenza, Human

India
University Hospital, Basel, Switzerland

Completed

Triage - Symptoms and Other Predictors in an All-comer Emergency Department Population (EMERGE VI)

Triage Risk Stratification

Switzerland
University Hospital, Gentofte, Copenhagen

Completed

Effect of PROGRESSive Training and Teststerone in Older Frail Men (PROGRESS)

Muscle Weakness

Denmark
Sanofi Pasteur, a Sanofi Company

Completed

Study on a MenACYW Conjugate Vaccine Administered as a Single Dose in Participants Aged 12 Months and Older in Vietnam

Healthy Volunteers | Meningococcal Infection

Vietnam
Academic and Community Cancer Research United
National Cancer Institute (NCI)

Active, not recruiting

Nivolumab and Brentuximab Vedotin in Treating Older Patients With Untreated Hodgkin Lymphoma

Ann Arbor Stage III Hodgkin Lymphoma | Ann Arbor Stage IIIA Hodgkin Lymphoma | Ann Arbor Stage IIIB Hodgkin Lymphoma | Ann Arbor Stage IV Hodgkin Lymphoma | Ann Arbor Stage IVA Hodgkin Lymphoma | Ann Arbor Stage IVB Hodgkin Lymphoma | Classic Hodgkin Lymphoma | Ann Arbor Stage IB Hodgkin Lymphoma | Ann... and other conditions

United States
University of California, Davis
National Institutes of Health (NIH); National Institute on Aging (NIA)

Active, not recruiting

High-dose Vitamin D Supplements in Older Adults

Vitamin D Deficiency | Cognitive Decline

United States
Janssen Research & Development, LLC

Active, not recruiting

A Study of 9-valent Extraintestinal Pathogenic Escherichia Coli Vaccine (ExPEC9V) and High-dose Quadrivalent Influenza Vaccine, With and Without Co-administration, in Adults Aged 65 Years or Older (Engage)

Invasive Extraintestinal Pathogenic Escherichia Coli Disease (IED) Prevention

United States, Poland, Belgium, Canada
Merck Sharp & Dohme LLC

Completed

A Study to Evaluate the Safety, Tolerability, and Immunogenicity of V114 When Administered Concomitantly With Influenza Vaccine in Healthy Adults 50 Years of Age or Older (V114-021/PNEU-FLU)

Pneumococcal Infections

United States
University of Cadiz
European Regional Development Fund; Universidad de Almeria; Ministerio de Ciencia... and other collaborators

Active, not recruiting

Cost-effectiveness and Efficacy of Different Physical Exercise Interventions (ExerMOT4Health) (ExerMOT4Health)

Healthy Aging | Physical Inactivity | Older Adult

Spain
Goethe University

Completed

Treatment of Older Patients With B-precursor ALL With Sequential Dose Reduced Chemotherapy and Blinatumomab (EWALL-BOLD)

B-Precursor ALL

Germany
GlaxoSmithKline

Completed

A Study on the Immune Response and Safety of a Vaccine Against Respiratory Syncytial Virus Given to Adults 50-59 Years of Age, Including Adults at Increased Risk of Respiratory Syncytial Virus Lower Respiratory Tract Disease, Compared to Older Adults 60 Years of Age and Above

Respiratory Syncytial Virus Infections

Argentina, United States, Germany, Spain, Poland, Canada, Japan, Netherlands
National Cancer Institute (NCI)

Active, not recruiting

Azacitidine and Gemtuzumab Ozogamicin in Treating Older Patients With Previously Untreated Acute Myeloid Leukemia

Acute Myeloid Leukemia | Secondary Acute Myeloid Leukemia | Adult Acute Monoblastic Leukemia | Adult Acute Monocytic Leukemia | Adult Acute Myeloid Leukemia With Inv(16)(p13.1q22); CBFB-MYH11 | Adult Acute Myeloid Leukemia With Maturation | Adult Acute Myeloid Leukemia With t(16;16)(p13.1;q22)... and other conditions

United States
Case Western Reserve University
Patient-Centered Outcomes Research Institute

Active, not recruiting

Older Adult Effectiveness of 2 Treatments

Dental Caries

United States
Ohio State University Comprehensive Cancer Center
MorphoSys AG

Active, not recruiting

Phase II MOR00208 in Combination With Lenalidomide for Patients With Relapsed or Refractory CLL, SLL or PLL or Older Patients With Untreated CLL, SLL or PLL

Recurrent Small Lymphocytic Lymphoma | Prolymphocytic Leukemia | Refractory Chronic Lymphocytic Leukemia | Stage III Small Lymphocytic Lymphoma | Stage IV Small Lymphocytic Lymphoma | Stage I Chronic Lymphocytic Leukemia | Stage II Chronic Lymphocytic Leukemia | Contiguous Stage II Small Lymphocytic... and other conditions

United States
University of Texas Southwestern Medical Center
Michigan State University; Texas Health Resources

Completed

Hypertension, Intracranial Pulsatility and Brain Amyloid-beta Accumulation in Older Adults (HIPAC Trial) (HIPAC)

Hypertension

United States
Duke University
National Institute on Aging (NIA)

Completed

Deprescribing for Older Dialysis Patients

Kidney Failure, Chronic

United States
Université de Sherbrooke

Active, not recruiting

Optimal VAsopressor TitraTION in Patients 65 Years and Older (OVATION-65)

Hypotension | Usual Care | Vasopressors | Mean Arterial Pressure Targets

Canada
Takeda

Completed

A Study of Teduglutide in Japanese Children With Short Bowel Syndrome Aged 4 Months or Older

Short Bowel Syndrome

Japan
Janssen Vaccines & Prevention B.V.

Terminated

A Study of an Ad26.RSV.preF-based Regimen in the Prevention of Reverse Transcriptase Polymerase Chain Reaction (RT-PCR)-Confirmed Respiratory Syncytial Virus (RSV)-Mediated Lower Respiratory Tract Disease in Adults Aged 65 Years and Older (CYPRESS)

Respiratory Tract Diseases | Respiratory Syncytial Viruses

United States
University of Exeter
University of Leeds; National Institute for Health Research, United Kingdom

Completed

Exploring 'VOLITION' in Context - a Study to Inform the Implementation of a New Intervention (VOLITION)

Aged | Multimorbidity | Decision Making | General Practice

United Kingdom
National University of Singapore
National University Hospital, Singapore; Lions Befrienders Service Association...

Completed

Effect of Singapore-contextualized Dance-based Exergame Among Community-dwelling Older Adults

Community-dwelling Older Adults

Singapore
Organon and Co

Completed

Ezetimibe and Atorvastatin vs. Atorvastatin in Patients Age 65 and Older at High Risk for Coronary Heart Disease (CHD)(0653-112)

Hypercholesterolemia
UCB Biopharma SRL

Enrolling by invitation

A Study to Test the Safety and Tolerability of Staccato Alprazolam in Study Participants 12 Years of Age and Older With Stereotypical Prolonged Seizures

Stereotypical Prolonged Seizures

United States, Bulgaria, China, Czechia, Germany, Hungary, Italy, Japan, Poland, Spain, United Kingdom, Australia
Sanofi Pasteur, a Sanofi Company

Completed

Safety and Immunogenicity of Quadrivalent Influenza mRNA Vaccine MRT5413 in Adult Participants18 Years of Age and Older

Influenza Immunization

Australia, United States, Puerto Rico
Sanofi Pasteur, a Sanofi Company
GlaxoSmithKline

Completed

Study of Recombinant Protein Vaccines With Adjuvant as a Primary Series and as a Booster Dose Against COVID-19 in Adults 18 Years of Age and Older (VAT00002)

COVID-19

Honduras, United States, Australia, France, New Zealand, Spain, United Kingdom
Universitaire Ziekenhuizen KU Leuven

Active, not recruiting

A Phase IV Study to Collect Data on the Efficacy and Safety of RIBociclib in Older Women With Breastcancer (RibOB)

Breast Cancer

Belgium
Sidney Kimmel Comprehensive Cancer Center at Johns...
National Institutes of Health (NIH); National Institute on Aging (NIA)

Active, not recruiting

Resiliency in Older Adults Undergoing Bone Marrow Transplant (REBOUND)

Lymphoma | Leukemia | Myelodysplastic Syndrome | Acute Myelogenous Leukemia | Non-Hodgkins Lymphoma | Blood Cancer

United States
Medical College of Wisconsin

Active, not recruiting

Singing and Cardiovascular Health in Older Adults

Cardiovascular Diseases | Cardiovascular Risk Factor | Cardiovascular Health

United States
The University of Texas Health Science Center at...
National Institute on Aging (NIA)

Active, not recruiting

Effect of GLP1 Receptor Agonists on Physical Function, Body Composition, and Markers of Aging in Older Adults

Diabetes Mellitus, Type 2 | PreDiabetes | Aging | Overweight and Obesity

United States
Memorial Sloan Kettering Cancer Center

Active, not recruiting

Comprehensive Geriatric Assessment to Predict Toxic Events in Older Patients With Non-Hodgkin Lymphoma With Imbedded Pilot Study of Pre-Phase Therapy

Diffuse Large B-cell Lymphoma (DLBCL) | Non Hodgkin Lymphoma (NHL)

United States
Sanofi Pasteur, a Sanofi Company

Active, not recruiting

Study of a Respiratory Syncytial Virus Candidate Encapsulated in a Lipid Nanoparticle Based Formulation in Adults Aged 18 to 50 Years and 60 Years and Older

Respiratory Syncytial Virus Immunization

United States, Australia, Puerto Rico
Boehringer Ingelheim

Completed

A Study to Test How Well Empagliflozin Works in Japanese People With Type 2 Diabetes Who Are Older Than 65 Years

Diabetes Mellitus, Type 2

Japan
City of Hope Medical Center
National Institute on Aging (NIA)

Active, not recruiting

Technology to Assess Vulnerable Older Adults With Cancer and Their Caregivers

Cancer | Solid Tumor | Hematologic Malignancy

United States
SFJ Pharmaceuticals, Inc.

Completed

Study to Evaluate the Safety, Tolerability, PK and PD of PB2452 in Healthy Younger, Older and Elderly Subjects

Healthy

United States
Cynthia Owusu, MD
National Cancer Institute (NCI)

Completed

Trastuzumab in Treating Older Women With Early-Stage Breast Cancer

Breast Cancer

United States
Celgene

Completed

An Efficacy and Safety Study of AG-221 (CC-90007) Versus Conventional Care Regimens in Older Subjects With Late Stage Acute Myeloid Leukemia Harboring an Isocitrate Dehydrogenase 2 Mutation (IDHENTIFY)

Leukemia, Myeloid | Isocitrate Dehydrogenase

United States, Canada, China, Czechia, France, Germany, Italy, United Kingdom, Australia, Austria, Brazil, Denmark, Korea, Republic of, Russian Federation, Spain, Taiwan, Turkey, Belgium
Oslo University Hospital
University of Melbourne; Norwegian Academy of Music

Completed

Music Therapy as a Treatment for Delirium in Acutely Hospitalized Older Patients

Delirium in Old Age | Delirium of Mixed Origin | Delirium Superimposed on Dementia | Delirium Confusional State

Norway
CureVac

Completed

A Phase 2b/3, Randomized, Observer-Blinded, Placebo-Controlled, Multicenter Clinical Study Evaluating the Efficacy and Safety of Investigational SARS-CoV-2 mRNA Vaccine CVnCoV in Adults 18 Years of Age and Older

Covid19 | SARS-CoV-2

Belgium, Spain, Germany, Argentina, Colombia, Dominican Republic, Mexico, Netherlands, Panama, Peru
Centre Hospitalier Universitaire de Saint Etienne

Active, not recruiting

Cohort Assessing the Immunogenicity and the Safety of the COVID-19 Vaccine Janssen in Healthy Volunteers Based on 2 Age Groups: 65 Years or Older - 55 to 65 Years. Covicompare-Janssen (CoviCompare_J)

Healthy Volunteers

France
Trak Health Solutions S.L.
University of the Basque Country (UPV/EHU); Basque Health Service

Completed

A Digital Home-Based Physiotherapy Program for Active Aging (TRAK)

Frail Elderly Syndrome | Older Adults

Spain
Women's College Hospital
University Health Network, Toronto

Completed

Feasibility of an Online, Self-administered Cognitive Screening Tool in Older Patients Undergoing Ambulatory Surgery (FOCUS)

Neurocognitive Disorders | Alzheimer Disease | Mild Cognitive Impairment | Delirium in Old Age

Canada
Sanofi Pasteur, a Sanofi Company

Completed

Safety and Immunogenicity of Quadrivalent Influenza mRNA Vaccine MRT5410 in Adult Participants 18 Years of Age and Older

Influenza Immunization

United States, Puerto Rico
Soroka University Medical Center

Completed

The Effect of Fluids Consumption on Balance and Gait Function in Old Adults

Aging | Dehydration

Israel
Wake Forest University Health Sciences
Bristol-Myers Squibb; Atrium Health Levine Cancer Institute

Active, not recruiting

Nivolumab Consolidation in Older (≥ 65) Patients With Primary CNS Lymphoma

Brain and Nervous System | Eye and Orbit

United States
Zhu Dian

Active, not recruiting

Immersive VR Reminiscence System for Facilitating Memory Retrieval Among Nursing Home Older Adults

Emotional Regulation | Old Age | Memory, Repressed

China
Weill Medical College of Cornell University
Agency for Healthcare Research and Quality (AHRQ)

Active, not recruiting

Improving How Older Adults at Risk for Cardiovascular Outcomes Are Selected for Care Coordination

Myocardial Infarction | Cardiovascular Diseases | Heart Failure | Stroke | Hypertension | Diabetes Mellitus | Atrial Fibrillation | Transient Ischemic Attack | Hyperlipidemias | Ischemic Heart Disease

United States
Pfizer

Active, not recruiting

Korea Comirnaty Post-marketing Surveillance

COVID-19 | SARS-CoV-2 | Adverse Effects | Safety | Vaccines

Korea, Republic of
The Hong Kong Polytechnic University

Completed

Self-administered Acupressure for Knee Osteoarthritis in Middle- and Older-Aged Adults

Knee Osteoarthritis

Hong Kong
GlaxoSmithKline

Completed

Study to Evaluate Immunogenicity and Safety of GSK Biologicals' Herpes Zoster Subunit (HZ/su) Vaccine at 9 and 10 Years After Vaccine Administration and Assessment of Re-vaccination With 2 Additional Doses at 10 Years After Initial Vaccination, in Healthy Subjects Aged 60 Years of Age(YOA) and Older

Herpes Zoster

Germany, Czechia, Sweden
Tufts University

Completed

StrongWomen- Healthy Hearts: A Community Based Program for Midlife and Older Women

Cardiovascular Diseases | Overweight and Obesity

Search clinical trials for: older age

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