Search clinical trials for: repeat dose

Total 22079 results

GlaxoSmithKline

Completed

A Study To Evaluate Formulations And Food Effect On GSK364735 In Healthy Subjects.

HIV Infection | Infection, Human Immunodeficiency Virus

United States
GlaxoSmithKline

Completed

Study To Evaluate GSK256066 In Subjects With Mild Bronchial Asthma

Asthma | Mild Asthma

United Kingdom
Trio Medicines Ltd.
James Black Foundation

Completed

Effect of Repeated Doses of YF476 on Stomach Acidity

Hypergastrinaemia

United Kingdom
Trio Medicines Ltd.
Ferring Pharmaceuticals

Completed

Effect of Repeated Doses of YF476, Omeprazole and Placebo on Stomach Acidity in Healthy Volunteers

Reflux Oesophagitis

United Kingdom
Accenture

Completed

Repeat Dose Safety Study for Compound to Treat Hematologic Cancer

Hematologic Malignancies

Korea, Republic of, Australia, Canada
GlaxoSmithKline

Completed

A Placebo-controlled Study to Investigate the Safety, and Pharmacokinetics of Oral GSK626616AC in Healthy Subjects

Healthy Subjects | Anaemia

Australia
BioCryst Pharmaceuticals

Completed

Repeat-Dose of Forodesine Hydrochloride (BCX-1777) Infusion in Patients With Advanced T-Cell Leukemia

Leukemia, T-Cell

United States, Georgia
Hospira, now a wholly owned subsidiary of Pfizer

Completed

Safety and Efficacy of Repeated Doses of PMI-150 (Intranasal Ketamine) in Acute Post-operative Pain Following Orthopedic Surgery

Pain, Postoperative

United States
Kubota Vision Inc.
Otsuka Pharmaceutical Co., Ltd.

Completed

Safety and Tolerability of Repeat Doses of ACU-4429 in Healthy Subjects

Healthy

United States
Novartis

Completed

An Exploratory Study, to Assess the Effect of Repeat-dose Inhaled Indacaterol Maleate (300 μg) on Dynamic and Static Lung Hyperinflation, Subjective Breathlessness and Health Status in Patients With Chronic Obstructive Pulmonary Disease(COPD)

Chronic Obstructive Pulmonary Disease

Germany
NicOx

Completed

Effect of Repeated Dosing of Naproxcinod on Renal Hemodynamic and on Sodium Balance in Healthy Volunteers Before and After a Single Dose of Furosemide

Renal Hemodynamics
AstraZeneca

Completed

Study to Assess the Safety and Tolerability of AZD1152 in Combination With Low Dose Cytosine Arabinoside (LDAC)

Acute Myeloid Leukemia

United States, France
Peregrine Pharmaceuticals

Completed

Bavituximab Repeat-Dose Trial in Patients Co-Infected With Chronic Hepatitis C Virus and Human Immunodeficiency Virus

Hepatitis C Virus | Hiv Infections

United States
Ferring Pharmaceuticals

Terminated

Extension Study Investigating the Long-Term Safety and Tolerability of Repeat Doses of FE200486 in Prostate Cancer Patients

Prostate Cancer

United States
Ferring Pharmaceuticals

Terminated

Study Investigating the Long-Term Safety and Tolerability of Repeated Doses of Degarelix in Prostate Cancer Patients

Prostate Cancer
Ferring Pharmaceuticals

Terminated

Extension Study Investigating the Long-Term Safety and Tolerability of Repeat Doses of FE200486 in Prostate Cancer Patients

Prostate Cancer
Tibotec Pharmaceuticals, Ireland

Completed

TMC435350-TiDP16-C101 - A Study to Examine the Safety, Tolerability and Pharmacokinetics of Increasing Oral Doses of TMC435350 After Single and Repeated Dosing

Hepatitis C
University of California, San Francisco

Completed

Analgesic Tolerance to Repeated Doses of Subcutaneous Morphine

Healthy Volunteers

United States
AstraZeneca

Completed

A Study to Assess the Safety, Tolerability and Pharmacokinetics of Modified-Release Formulations of AZD1446 After Oral Single and Repeated Doses

Healthy

Japan
Merz Pharmaceuticals GmbH

Completed

Evaluation of Dose-Dependent Repeated-Dose Neramexane Effects on Cardiac Repolarisation (QT/QTc Interval Duration): Electrocardiogram (ECG) Study in Healthy Adult Subjects

Healthy Subjects

Germany
Accenture

Completed

Repeat Dose Safety Study for Compound to Treat Asthma

Asthma

Australia
Heidelberg University

Completed

Study to Investigate the Pharmacodynamics, Pharmacokinetics and Safety of a Single Oral Repeated Dose of 500 mg Nicotinic Acid as Tablets in Healthy Subjects

Healthy Subjects
AstraZeneca

Completed

Study of an Extended Release (ER) Tablet, Single and Repeated Dosing

Healthy

Sweden
Pfizer

Completed

Estimate The Effect Of Repeat-Dose Rifampin On The Pharmacokinetics Of CP-690,550 In Healthy Volunteers

Healthy

United States
GlaxoSmithKline

Completed

A Study to Compare COREG CR to COREG CR Fixed-dose Combination in Patients With High Blood Pressure

Hypertension

United States
GlaxoSmithKline

Completed

A Drug Interaction Study Between Simvastatin and GSK376501

Type 2 Diabetes Mellitus

United States
GlaxoSmithKline

Completed

GW823296 Repeat Dose Study In Healthy Male And Female Subjects

Healthy Subjects

Australia
GlaxoSmithKline

Completed

Evaluation of Single and Repeat Doses of GSK729327 in Healthy Volunteers

Schizophrenia

Germany, United Kingdom
Jerini Ophthalmic

Completed

A Phase 1 Safety Study of Single and Repeated Doses of JSM6427 (Intravitreal Injection) to Treat AMD

Macular Degeneration

United States
Sanofi

Completed

Cohort Study in Senegal Comparing Artesunate + Amiodaquine in the Treatment of Repeated Uncomplicated Plasmodium Falciparum Malaria Attacks

Malaria

Senegal
Tibotec Pharmaceuticals, Ireland

Completed

PEPI-TiDP23-C103: First-in-Human Study to Examine the Safety, Tolerability, and Plasma Pharmacokinetics of Increasing Single and Repeated Oral Doses of TMC558445 and of a Combined Single Day Dosing of Oral TMC558445 and Oral TMC310911 and Also Oral Darunavir

HIV-1
Alza Corporation, DE, USA

Completed

A Repeated-Dose Evaluation of a Pain Relieving Drug Use and Safety of OROS Hydromorphone HCI in Patients With Chronic Non-Malignant Pain

Pain | Analgesics | Opioid
Alza Corporation, DE, USA

Completed

A Repeated-Dose Evaluation of Use of a Pain Relieving Drug and Safety of OROS Hydromorphone HCI in Patients With Chronic Cancer Pain

Pain | Analgesics, Opioid
Alza Corporation, DE, USA

Completed

Safety and Tolerability of Long-term Administration of OROS Hydromorphone HCI (Slow Release) in Cancer Pain

Pain | Analgesics, Opioid
Amgen

Completed

A Study of Repeat-Dose Subcutaneous Darbepoetin Alfa in Subjects With Congestive Heart Failure and Anemia, and a Single Dose in Healthy Age- and Sex-Matched Control Subjects

Anemia | Congestive Heart Failure
AstraZeneca

Completed

Phase I Study in Healthy Volunteers to Assess the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of AZD4017 After Repeated Ascending Oral Doses (MAD)

Diabetes Mellitus Type 2

Sweden
Renovo

Completed

Safety Study of Repeated, Escalating Doses of Intradermal Avotermin (Juvista)

Cicatrix | Wound Healing

United Kingdom
GlaxoSmithKline

Terminated

A Repeat Dose Study With GSK1018921 to Assess Safety, Tolerability, Pharmacokinetics, Pharmacodynamics in Healthy Volunteers and Patients With Schizophrenia and to Evaluate Its Effect on PK of Midazolam. (GT1110791)

Schizophrenia

United States
GlaxoSmithKline

Completed

Effects Of Repeat Inhaled Doses Of GW597901X On Patient Safety And Lung Function In Asthmatic Subjects

Asthma
Millennium Pharmaceuticals, Inc.

Completed

Repeat-Dose Pharmacokinetics and Pharmacodynamics of Bortezomib in Patients With Relapsed Multiple Myeloma

Multiple Myeloma
GlaxoSmithKline

Completed

Dose-Escalating Study Of SB-485232 Administered Intravenously Every 28 Days To Adults With Solid Tumors Or Lymphomas

Lymphoma | Solid Tumor Cancer

United States
AstraZeneca

Completed

Investigate the Effect on the QT/QTc Interval of Repeated and Escalating Doses of AZD3480 During 6 Days (TQT)

Healthy
Orion Corporation, Orion Pharma

Completed

Pharmacokinetic Study With Repeated Doses of Stalevo

Pharmacokinetics

Finland
Peregrine Pharmaceuticals

Completed

Repeat-Dose Study of Bavituximab in Patients With Chronic Hepatitis C

Hepatitis C

United States
University Hospital, Montpellier

Completed

Assessment of Bupropion on Cognitive Function and Behaviour in Healthy Volunteers

Healthy

France
Assistance Publique - Hôpitaux de Paris
Danone Institute International

Terminated

Effects of Peptides Derived From Fermented Milk on Blood Pressure Regulation System in Healthy Volunteers.

Healthy

France
Chang Gung Memorial Hospital

Completed

Long-Term Lead Chelation Therapy and Progressive Renal Insufficiency

Urologic Disease

China
Azienda Usl di Bologna

Recruiting

Renal Outcomes in the Early Use of Vasopressin in the Treatment of Septic Shock (EVSS)

Septic Shock | Renal Function Replacement

Italy
DSM Nutritional Products, Inc.
Nutrasource Pharmaceutical and Nutraceutical Services, Inc.

Not yet recruiting

A Pharmacokinetic Study of Single Oral Doses of Six Different Vitamin C Product Forms

Healthy | Pharmacokinetic
AstraZeneca

Not yet recruiting

A Study to Investigate Efficacy and Safety of PT027 Compared With PT007 in Symptomatic Chinese Adults With Asthma (BAIYUN)

Asthma

China

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