Search clinical trials for: severe

Total 8559 results

Icahn School of Medicine at Mount Sinai
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Not yet recruiting

Maternal And Infant Antipsychotic Study (MAIA)

Pregnancy | Antipsychotics
Erasmus Medical Center
Maasstad Hospital

Recruiting

FCV vs PCV in Moderate to Severe ARDS

Acute Respiratory Distress Syndrome | Ventilator Lung

Netherlands
Innovent Biologics (Suzhou) Co. Ltd.

Recruiting

IBI112 in Moderate to Severe Plaque Psoriasis With Randomized Withdrawal and Re-treatment

Psoriasis

China
Guy's and St Thomas' NHS Foundation Trust
King's College London

Not yet recruiting

Outcome Prediction in Patients With Aortic Stenosis After TAVI (PREDICT-TAVI)

Aortic Stenosis, Severe

United Kingdom
Janssen Research & Development, LLC

Recruiting

A Study of JNJ-77242113 in Participants With Moderately to Severely Active Ulcerative Colitis (ANTHEM-UC)

Colitis, Ulcerative

Korea, Republic of, Australia, United States, Czechia, Malaysia, Turkey, Japan, Belgium, Hungary, Canada, Italy, Spain, China, Poland, United Kingdom, Germany, Brazil, France, Argentina, Romania, India
Eli Lilly and Company

Recruiting

A Study of Eltrekibart (LY3041658) in Adult Participants With Moderate to Severe Hidradenitis Suppurativa

Hidradenitis Suppurativa

United States, Australia, Canada, Germany, Greece, Poland
University Hospital, Rouen

Recruiting

Dynamics of the Upper and Lower Airway Respiratory Microbiomes Associated With Severe Infant Asthma (Microbiosthme)

Asthma | Asthma in Children

France
Centers for Disease Control and Prevention

Recruiting

Virologic and Immunologic Characteristics of Severe Mpox in Persons With Advanced HIV (VIRISMAP)

HIV Infections | Monkeypox | AIDS

United States
Longbio Pharma

Recruiting

Efficacy and Safety of LP-003 in Moderate-to-severe Seasonal Allergic Rhinitis Adult

Seasonal Allergic Rhinitis

China
Nantes University Hospital
Fondation de France

Recruiting

Discovering New Insights Into Anorexia Nervosa: Influence of MicrObial DysbiosiS (DIAMOnDS) (DIAMOnDS)

Anorexia Nervosa

France
AnaptysBio, Inc.

Recruiting

A Study of Efficacy and Safety of Rosnilimab in Subjects With Moderate to Severe Rheumatoid Arthritis (RENOIR)

Rheumatoid Arthritis

United States, Argentina, Estonia, Georgia, Hungary, Mexico, Moldova, Republic of, Peru, Poland, Slovakia, Belgium, Canada, Germany, Italy, Spain
GlaxoSmithKline

Not yet recruiting

REIMAGINE - Real World EvaluatIon of Mepolizumab in Severe Asthma achievinG on Treatment clinIcal remissioN, a prospEctive Study (REIMAGINE)

Asthma
IGM Biosciences, Inc.

Recruiting

A Study of Imvotamab in Severe Systemic Lupus Erythematosus

Systemic Lupus Erythematosus | Lupus Erythematosus

United States, Korea, Republic of, Poland
Anhui Provincial Hospital

Recruiting

Conditioning Regimen Containing Low Dose ATG for The Treatment of Acquired SAA Receiving sUCBT

Severe Aplastic Anemia

China
Action Against Hunger USA
University of Washington; Ethiopian Public Health Institute

Not yet recruiting

Family Mid-Upper Arm Circumference (MUAC) Follow-up After Recovery From Acute Malnutrition (MODAM-fMUAC) (MODAM-fMUAC)

Moderate Acute Malnutrition | Severe Acute Malnutrition
Assistance Publique - Hôpitaux de Paris

Not yet recruiting

IHD Versus CRRT for Severe Acute Kidney Injury in Critically Ill Patients (ICRAKI)

Acute Kidney Injury
Jiangsu HengRui Medicine Co., Ltd.

Recruiting

A Study to Assess the Efficacy and Safety of HRG2005 Inhalation in Patients With Moderate to Severe Chronic Obstructive Pulmonary Disease

Chronic Obstructive Pulmonary Disease

China
Pulmonx Corporation

Recruiting

An Evaluation of the AeriSeal System for CONVERTing Collateral Ventilation Status in Patients With Severe Emphysema (CONVERT_II)

Emphysema or COPD | Emphysema, Pulmonary

Spain, Germany, Italy, Australia
Sun Yat-sen University

Recruiting

Prospective Observational Study to Predict Severe Oral Mucositis Associated With Chemoradiotherapy in Nasopharyngeal Carcinoma Based on Deep Learning

Nasopharyngeal Carcinoma | Oral Mucositis

China
German Asthma Net e.V.
Sanofi; GlaxoSmithKline; AstraZeneca; Chiesi Farmaceutici S.p.A.

Recruiting

Register Schweres Asthma - German Asthma Net e.V.

Severe Asthma

Germany
Sanofi

Recruiting

Long-term Safety and Efficacy Evaluation of Subcutaneous Amlitelimab in Adult Participants With Moderate-to-severe Asthma Who Completed Treatment Period of Previous Amlitelimab Asthma Clinical Study (RIVER-ASTHMA)

Asthma

Korea, Republic of, Argentina, Chile, South Africa, United States, Hungary, Poland, Turkey, United Kingdom, Canada, Japan
Lemonex

Recruiting

Evaluation of Safety and Immunogenicity of a SARS-CoV-2(Severe Acute Respiratory Syndrome Coronavirus 2) Booster Vaccine (LEM-mR203)

COVID-19 Infection | COVID-19 Vaccine Adverse Reaction

Korea, Republic of
Sanofi
Kymera Therapeutics, Inc.

Recruiting

A Phase 2 Study to Evaluate the Efficacy and Safety of SAR444656 Compared With Placebo in Adult Participants With Moderate to Severe Hidradenitis Suppurativa (ZEN)

Hidradenitis Suppurativa

Spain, United States, Germany, Greece, Poland
Almirall, S.A.

Recruiting

A Study to Assess the Effects of Switching From a Biologic Treatment to Tildrakizumab Using Patient-reported Outcomes in Adult Participants With Moderate to Severe Plaque Psoriasis

Plaque Psoriasis

Austria
Gilead Sciences

Recruiting

Study of Tilpisertib Fosmecarbil in Participants With Moderately to Severely Active Ulcerative Colitis (PALEKONA)

Ulcerative Colitis

United States, Australia, United Kingdom, Korea, Republic of, Japan, Italy, France, Canada, Switzerland, Austria, Germany, Hungary, Poland
Assistance Publique Hopitaux De Marseille

Recruiting

Impact of an Alternative to Incarceration by Housing and Support by Assertive Community Treatment Team for Homeless People With Severe Psychiatric Disorders Referred to Immediate Referral Procedure: AILSI Program (AILSI)

Severe Psychiatric Disorder

France
Third Wave Therapeutics

Recruiting

Sonu Real-World Use Clinical Study to Treat Moderate to Severe Nasal Congestion

Nasal Congestion

United States
AbbVie

Recruiting

An Observational Study to Assess Change in Disease Activity and Adverse Events in Adolescent and Adult Participants With Moderate to Severe Active Crohn's Disease (CD) in Japan

Crohn's Disease

Japan
Nova Scotia Health Authority

Not yet recruiting

PATH Program for for Severely Frail or Cognitively Impaired Patients Scheduled for Cancer Surgery.

Cognitive Impairment | Frailty | Oncology Problem

Canada
AstraZeneca
Amgen

Recruiting

A Study to Investigate the Efficacy and Safety of Tezepelumab Compared With Placebo in Children 5 to < 12 Years Old With Severe Asthma (HORIZON)

Asthma

United States, Poland, Korea, Republic of, Spain, France, China, United Kingdom, Canada, Netherlands, Argentina, Mexico, Brazil, Hungary, Japan, Philippines, South Africa, Colombia
Lady Reading Hospital, Pakistan
Pakistan Chest Society, Pakistan

Recruiting

Clopidogrel for the Prevention of Exacerbations in Severe COPD (CLOPEX)

COPD | COPD Exacerbation Acute

Pakistan
Third Wave Therapeutics

Recruiting

Sounds for Sleep Study in Patients Suffering From Moderate to Severe Insomnia

Insomnia

United States
Instituto Nacional de Psiquiatría Dr. Ramón de...
Columbia University; Research Foundation for Mental Hygiene, Inc.; Instituto...

Not yet recruiting

Individual Placement and Support Mexico (IPS)

Severe Mental Disorder

United States, Mexico
AstraZeneca

Recruiting

Phase 2a Study to Assess the Efficacy and Safety of AZD4604 in Adult Patients With Moderate-to-Severe Asthma Uncontrolled on Medium-High Dose ICS-LABA (AJAX)

Asthma

Denmark, United States, South Africa, United Kingdom, Argentina, Vietnam, Brazil, Malaysia, Taiwan, France, Germany, Spain, Thailand, Bulgaria, Philippines, Sweden
Assistance Publique - Hôpitaux de Paris

Not yet recruiting

Systematic Use of DDAVP to Prevent Serum Sodium Overcorrection in Severe Hyponatremia: a Multicenter Open-label Randomized Controlled Trial (DASSOH)

Hyponatremia
Sanofi

Recruiting

A Study to Evaluate the Quality of Life in Male and Female Adult Participants With Severe Asthma Treated With Dupilumab in a Real-world Setting (PROVERB)

Asthma

France
Postgraduate Institute of Dental Sciences Rohtak

Not yet recruiting

Evaluation of Macrophage Inflammatory Protein-1α as a Periodontal Disease Biomarker

Gingivitis | Inflammatory Response | Periodontitis Chronic Generalized Severe

India
Institut National de la Santé Et de la Recherche...

Recruiting

Characterization of Natural Killer Cells in Severe Asthma Patients in Comparison With Control Subjects (NKAS)

Asthma Acute

France
Jordan Collaborating Cardiology Group

Not yet recruiting

Prevalence of ATTR Cardiac Amyloidosis in Patients Undergoing TAVR

Aortic Valve Stenosis | Severe Aortic Stenosis | ATTR Amyloidosis Wild Type | Middle East Studies
Taipei Medical University Hospital
Taipei Medical University; Panion & BF Biotech Inc.

Recruiting

Polymeric Microspheres vs Sculptra® in the Treatment of Moderate to Severe Nasolabial Folds

Nasolabial Fold Wrinkles

Taiwan
Mansoura University

Recruiting

Subperiosteal Implants Constructed With Digital Technology

Alveolar Bone Loss

Egypt
Tongji Hospital

Recruiting

A 6-month Follow-up Study of Patients With Severe Fever With Thrombocytopenia Syndrome

Severe Fever With Thrombocytopenia Syndrome

China
University of California, San Francisco
Centre de Recherche en Sante de Nouna, Burkina Faso

Not yet recruiting

Azithromycin as Adjunctive Treatment for Uncomplicated Severe Acute Malnutrition (AMOUR)

Malnutrition, Child | Severe Acute Malnutrition

Burkina Faso
AbbVie

Recruiting

A Study to Evaluate the Safety and Effectiveness of Upadacitinib Tablets in Adult and Adolescent Participants With Severe Alopecia Areata (Up-AA)

Alopecia Areata

United States, Australia, Japan, Puerto Rico, New Zealand, China, Canada, Brazil, United Kingdom, Korea, Republic of
Peking Union Medical College Hospital

Not yet recruiting

Romiplostim in Combination With CsA vs. CsA in the Treatment of Newly Diagnosed NSAA

Non Severe Aplastic Anemia

China
Food and Health Bureau, Hong Kong
Hospital Authority, Hong Kong

Not yet recruiting

A Decision Aid on End-of-life Care for Patients With Advanced COPD and Their Family

Chronic Obstructive Pulmonary Disease Severe
LEO Pharma

Recruiting

A Trial to Evaluate Efficacy, Safety, and Pharmacokinetics of Delgocitinib Cream in Chinese Adults and Adolescents With Moderate to Severe Chronic Hand Eczema

Chronic Hand Eczema

China
Novartis Pharmaceuticals

Recruiting

Study of Lutetium (177Lu) Vipivotide Tetraxetan in mCRPC Participants With Moderately and Severely Impaired and With Normal Renal Function

Metastatic Castration-Resistant Prostate Cancer (mCRPC)

Spain, France
Mental Health Services in the Capital Region, Denmark
Innovation Fund Denmark

Recruiting

T-PEMF Headband Stimulation for Patients With Moderate to Servere Depression

Moderate Depression | Recurrent Depressive Disorder, Current Episode Moderate | Severe Depressive Episode Without Psychotic Symptoms | Recurrent Depressive Disorder, Current Episode Severe Without Psychotic Symptoms

Denmark
Wen Jiang-3
Xijing Hospital; Xi'an Central Hospital; Tongji Hospital; Qilu Hospital of Shandong... and other collaborators

Recruiting

Optimizing Early Nutrition Support in Severe Stroke-2

Dysphagia | Acute Stroke | Severe Stroke

China

Search clinical trials for: severe

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