Search clinical trials for: single oral dose

Total 41182 results

Bial - Portela C S.A.

Completed

The Tolerability and Effect of Food on the Pharmacokinetics of a Single 800 mg Oral Dose of BIA 2-093

Epilepsy
AstraZeneca

Completed

A Study to Assess the Safety, Tolerability and Pharmacokinetics of AZD9977 After Single Ascending Doses to Healthy Males

Healthy Subjects | Pharmacokinetics | Tolerability | Safety

United Kingdom
Universidad Autonoma de Baja California

Completed

The Outcome of Preoperative Administration of Single-dose Ketorolac, Non-steroidal Anti-inflammatory Drug and Placebo (PreOp)

Pulpitis - Irreversible

Mexico
Mallinckrodt

Completed

Single-Dose PK Study of an Oxycodone/Acetaminophen Solution in Healthy Subjects

Healthy Volunteers

United States
Pfizer

Completed

A Bioequivalence Study Comparing A Fixed Dose Combination Formulation Of Myrin P Forte That Contains Rifampicin, Isoniazid, Ethambutol And Pyrazinamide Per Tablet To An Equivalent Dose Of Single Drug Reference Preparations Of Similar Combination Following Oral Administration In Healthy Adults

Healthy Volunteers

Singapore
Galera Therapeutics, Inc.
INC Research Australia Pty Ltd; Nucleous Network

Completed

A Study of the Safety, Tolerability and Pharmacokinetics of Orally-administered GC4702 in Healthy Volunteers

Healthy Volunteer

Australia
AstraZeneca

Completed

A Study to Assess the Pharmacodynamic Effect of Single Doses of AZD9977 in Healthy Male Subjects

Healthy Subjects | Pharmacodynamics

United Kingdom
Bial - Portela C S.A.

Completed

Pharmacokinetics of Rising Single-doses of BIA 6-512 and Their Effect on the Levodopa Pharmacokinetics

Parkinson Disease

Portugal
GlaxoSmithKline

Completed

Single Oral Dose Study of Atovaquone/Proguanil Hydrochloride Combination Tablets and Atovaquone Suspension

Malaria

Japan
Melinta Therapeutics, Inc.

Completed

Safety and Efficacy Study of Single-Dose Oral CEM-101 in Patients With Uncomplicated Urogenital Gonorrhea

Uncomplicated Urogenital Gonorrhea

United States
Janssen Research & Development, LLC

Completed

A Crossover Study to Evaluate the Relative Oral Bioavailability and Food Effect After Single Dose Administration of JNJ-54861911 Tablet in Healthy Elderly Participants

Healthy

Belgium
Gesellschaft fur Medizinische Innovation - Hamatologie...

Completed

Lenalidomide/Low-dose Dexamethasone in Combination With Continuous Oral Cyclophosphamide Compared to Lenalidomide/Low-dose Dexamethasone Combined With Single Cyclophosphamide Doses IV in Patients With Relapsed/Refractory Multiple Myeloma (MM_LEN_DEX_CY)

Multiple Myeloma

Germany
Actelion

Completed

Absolute Bioavailability of a Single Oral Dose of Selexipag in Healthy Subjects

Healthy Subjects

France
Egalet Ltd

Completed

A Single-dose Study of Intranasal Ketorolac in the Treatment of Pain Secondary to Dental Impaction Surgery

Pain | Dental Impaction

United States
Celgene

Completed

A Single Dose Oral Excretion Balance Study of [14C]-RPC1063 in Healthy Male Adults

Healthy Volunteers

United Kingdom
Janssen Research & Development, LLC

Completed

To Evaluate the Effects of Odalasvir and AL-335 With Simeprevir on the Single-Dose Pharmacokinetics of Ethinylestradiol and Drospirenone in Healthy Female Participants

Healthy

United States
GlaxoSmithKline
Parexel; Medicines for Malaria Venture

Completed

A Study to Assess the Effects of Dissolution Profile on the Pharmacokinetics of Single Oral Doses of Tafenoquine Tablets and Tafenoquine Stable Isotope Labelled Solution

Malaria, Vivax

United States
Horizon Pharma Ireland, Ltd., Dublin Ireland
Ucyclyd Pharma, Inc.

Completed

A Study of Glyceryl Tri-(4-phenylbutyrate) Administered Orally as a Single Dose, and Twice Daily for Seven Consecutive Days to Subjects With Hepatic Impairment With Cirrhosis and to a Control Group

Hepatic Encephalopathy | Urea Cycle Disorders

Ukraine
SocraTec R&D GmbH
SocraMetrics GmbH

Completed

Ibuprofen Bioavailability Trial With Oral Single Dose Administration.

Bioequivalence

Germany
Alkermes, Inc.

Completed

ALK21-004: Single-dose Opiate Challenge of Medisorb® Naltrexone (VIVITROL®) in Adults Who Use Opioids

Opiate Dependence
National Institute on Drug Abuse (NIDA)

Unknown

A Phase 1 Parallel-Group, Double-Blind, Placebo-Controlled Cardiovascular and Behavioral Study Assessing Interactions Between Single Doses of Oral Reserpine and Intravenous Methamphetamine - 1

Amphetamine-Related Disorders

United States
AstraZeneca

Terminated

A Study to Assess the Safety and Tolerability of Single and Multiple Doses of AZD4831 in Healthy Male Subjects

Cardiovascular Disease
Boehringer Ingelheim

Completed

Relative Bioavailability of 2 Oral Formulations of Nintedanib

Healthy

Germany
SocraTec R&D GmbH
SocraMetrics GmbH

Completed

Characterisation of Relative Bioavailability With Bioequivalence Assessment of Deferiprone Tablets After Oral Single Dose Administration

Bioequivalence

Germany
GlaxoSmithKline

Completed

Allergen Challenge Chamber Study With Single Dose Oral GSK835726 Compared With Placebo

Rhinitis, Allergic, Seasonal

Germany
Genentech, Inc.

Completed

A Phase I Bioavailability and Pharmacokinetic Study of [14C]-Ipatasertib Single Oral and Intravenous Doses in Healthy Male Subjects

Healthy Volunteer

United States
Hoffmann-La Roche

Completed

A Two-part, Single-dose, Randomized Study to Evaluate the Safety of Supra-therapeutic Doses of RO7033877 and to Investigate the Effect of RO7033877 on the QTc Interval

Healthy Volunteer

United States
Genentech, Inc.

Completed

Study to Investigate the Absorption, Metabolism, and Excretion of [14C]-GDC-0941 Following Single Oral Dose Administration in Healthy Male Subjects

Healthy Volunteer

United States
Hoffmann-La Roche

Completed

A Study of The Excretion Balance, Pharmacokinetics and Metabolism of A Single Oral Dose of [14C]-Labeled RO4917523 in Healthy Male Volunteers

Healthy Volunteer

Netherlands
Genentech, Inc.

Completed

Study to Investigate the Absorption, Metabolism, and Excretion of [14C]-GDC-0980 Following Single Oral Dose Administration in Healthy Postmenopausal Female Subjects

Healthy Volunteer

United States
University of Saskatchewan
Saskatchewan Health Research Foundation

Completed

Single Oral Dose of BeneFlax to Healthy Young and Older Adults (SOD)

Diabetes Mellitus, Type 2 | Hypercholesterolemia

Canada
Otsuka Pharmaceutical Co., Ltd.

Completed

A Phase 1,Open -Label Study to Assess the Absorption, Metabolism and Excretion of 14C-OPS-2071 Following a Single Oral Dose to Healthy Male Japanese Subjects

Bacterial Enteritis

United Kingdom
AstraZeneca

Completed

A Phase I, Open-label Study to Assess Bioavailability of a Single Oral Dose of AZD9291 vs an IV Dose of [14C]AZD9291

Oncology

United Kingdom
Hoffmann-La Roche

Completed

A Study Investigating the Effect of Food and Esomeprazole on the Single Oral Dose Pharmacokinetics of Alectinib (RO5424802) in Healthy Volunteers.

Healthy Volunteer

United States
Prexton Therapeutics

Completed

A Phase I, Double Blind, Placebo Controlled, First in Human, Single and Multiple Ascending Oral Dose, Safety, Tolerability and Pharmacokinetic Study in Healthy Male and Female Subjects

Parkinson's Disease

United Kingdom
Johnson & Johnson Pharmaceutical Research & Development...

Withdrawn

A Study to Evaluate the Pharmacokinetic Drug Interaction Between Multiple Doses of JNJ-31001074 and a Single Dose of an Oral Contraceptive Containing Ethinyl Estradiol and Levonorgestrel in Women

Healthy | Pharmacokinetics | Drug Interactions
Bayer

Completed

To Evaluate the Bioavailability of a Single Oral Dose of the Acetylsalicylic Acid Containing Dry Powder 500 mg in Comparison to the Bioavailability of a Single Oral Dose of Aspirin Tablets and Aspirin Effervescent Tablets in Healthy Adults. (Icicle)

Pharmacology, Clinical

United States
F2G Biotech GmbH
Simbec-Orion Group

Completed

Single Ascending Oral Dose Study of F901318

Invasive Aspergillosis

United Kingdom
Boehringer Ingelheim

Terminated

Safety, Tolerability and Pharmacokinetics of Single Rising Oral Doses of BI 137882 in Healthy Male Volunteers

Healthy
Universitätsklinikum Hamburg-Eppendorf

Completed

Single and Multiple Doses of an Oral Formulation of L-Homoarginine in Healthy Human Subjects

Healthy
Gilead Sciences
Nimbus Apollo

Completed

Study to Evaluate the Pharmacodynamic Effects of a Single Oral Dose of GS-0976 (NDI-010976) in Healthy Adult Subjects

PD Effects of GS-0976 (NDI-010976) on Fractional DNL

United States
AstraZeneca

Completed

Study to Evaluate the 2-Way Interaction Between Multiple Doses of Epanova™ and a Single Dose of Rosuvastatin (Crestor®) (ECLIPSEIII)

Hypertriglyceridemia

United States
Bial - Portela C S.A.

Completed

A Single Centre, Phase I, Double-blind, Randomised, Placebo-controlled Study to Investigate the Safety, Tolerability, Pharmacokinetic Profile and Effects on EEG of Single Rising Oral Doses of BIA 2-093

Epilepsy

United Kingdom
Atopix Therapeutics, Ltd.
Simbec Research

Completed

First in Man Evaluation of Single and Multiple Doses of Oral ATX2417

Allergy

United Kingdom
Boryung Pharmaceutical Co., Ltd

Completed

Clinical Trials for Single Oral Dose of 60mg Fimasartan and Single IV Infusion of 30mg Fimasartan to Evaluate the Absolute Bioavailability of Kanarb® Tablet (Fimasartan) in Healthy Subjects

Healthy

Korea, Republic of
Astellas Pharma Global Development, Inc.
Yale University

Completed

A Positron Emission Tomography Occupancy Study Using Ligand [11C]AS2471907 and Following Oral Dosing of ASP3662

Healthy Volunteers | Pharmacokinetics of ASP3662 | Displacement of Radiotracer

United States
e-Therapeutics PLC

Completed

Assessment of Single Doses of Oral Dexanabinol in Healthy Subjects

Cancer | Pharmacokinetics | Tolerability | Safety

United Kingdom
Kissei Pharmaceutical Co., Ltd.

Completed

Study of Absorption, Metabolism and Excretion Following a Single Oral Dose of [14C]KWA-0711 to Healthy Male Subjects

Healthy Male Subject

United Kingdom
Novartis
Procter and Gamble

Completed

Study to Compare How the Body Changes the Blood Level of Darifenacin Tablet Form vs. the Modified Release Liquid Form in Healthy Subjects

Healthy

India
Flatley Discovery Lab LLC

Completed

FTIH - Single and Repeat Oral Doses of FDL169 in Healthy Volunteers

Cystic Fibrosis

United Kingdom

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