Search clinical trials for: diffusion of innovation

Total 432658 results

Celgene Corporation

Completed

D-MPH in the Treatment of Fatigue and Neurobehavioral Function Related to Chemotherapy in Adult Cancer Patients

Neoplasms | Fatigue

United States
FeRx

Unknown

Safety and Efficacy of Doxorubicin Adsorbed to Magnetic Beads

Hepatocellular Carcinoma

China
Eunice Kennedy Shriver National Institute of Child...
National Center for Research Resources (NCRR)

Unknown

Building Better Bones in Children

Osteoporosis

United States
Cellerix

Unknown

Autologous Stem Cells Derived From Lipoaspirates for the Non-Surgical Treatment of Complex Perianal Fistula

Anal Fistula

Spain
Gilead Sciences

Completed

A Phase I/II Study of the Safety and Efficacy of Topical 1-(S)-(3-Hydroxy-2-Phosphonylmethoxypropyl)Cytosine Dihydrate (Cidofovir; HPMPC) in the Treatment of Refractory Mucocutaneous Herpes Simplex Disease in Patients With AIDS

HIV Infections | Herpes Simplex

United States, Canada
Ionis Pharmaceuticals, Inc.

Completed

The Safety and Effectiveness of ISIS 2922 in Patients With AIDS Who Have Cytomegalovirus (CMV) of the Eyes

HIV Infections | Cytomegalovirus Retinitis

United States
Pharmacia

Completed

Rifabutin Therapy for the Prevention of Mycobacterium Avium Complex (MAC) Bacteremia in AIDS Patients With CD4 Counts = or < 200: A Double-Blind, Placebo-Controlled Trial

HIV Infections | Mycobacterium Avium-intracellulare Infection

United States, Canada
National Center for Research Resources (NCRR)

Completed

Congenital Adrenal Hyperplasia: Calcium Channels as Therapeutic Targets

Congenital Adrenal Hyperplasia

United States
Chiron Corporation

Completed

Safety and Efficacy of Polyethylene Glycolated IL-2 (PEG IL-2) Plus Zidovudine or Dideoxyinosine in HIV Positive, Asymptomatic and Symptomatic Individuals

HIV Infections

United States
American National Red Cross

Completed

A Pilot Study to Obtain Preliminary Information Regarding the Efficacy and Safety of the Combination of Immune Globulin and Ganciclovir as Compared to Ganciclovir Alone in the Treatment of Sight-Threatening CMV Retinitis in Patients With AIDS

HIV Infections | Cytomegalovirus Retinitis

United States
Pfizer

Completed

Open, Non-Comparative Study of Intravenous and Oral Fluconazole in the Treatment of Acute Cryptococcal Meningitis

HIV Infections | Meningitis, Cryptococcal

United States
St. Vincent's Medical Center

Completed

Depot Disulfiram for AIDS and ARC

HIV Infections

United States
Immunobiology Research Institute

Completed

Double Blind Study of Thymopentin Effects on Patients With HIV-1 Infection

HIV Infections

United States
Purdue Frederick
Walter Reed Army Institute of Research (WRAIR); Henry M. Jackson Foundation...

Completed

Phase I Study of Alferon N Injection in Persons With Asymptomatic Human Immunodeficiency Virus (HIV) Infection

HIV Infections

United States
Pharmacia

Completed

A Three-Arm Comparative Trial for the Treatment of MAC Bacteremia in AIDS: A Clarithromycin/Ethambutol Regimen Containing Rifabutin (450 Mg) or Rifabutin (300 Mg) or Placebo

HIV Infections | Mycobacterium Avium-Intracellulare Infection

United States
Pharmacia and Upjohn

Completed

A Double-Blind, Randomized, Comparative Study of Delavirdine Mesylate (U-90152S) in Combination With Didanosine (ddI) Versus ddI Alone in HIV-1 Infected Individuals With CD4 Counts of <= 300/mm3

HIV Infections

United States, Puerto Rico
Daiichi Pharmaceuticals

Completed

A Phase I Trial of Tecogalan Sodium ( DS-4152 ) Administered as an Infusion Twice Weekly for 21 Days.

HIV Infections | Sarcoma, Kaposi

United States
Gilead Sciences

Completed

A Multi-Center, Randomized, Double-Blind, Placebo-Controlled Study of the Efficacy and Safety of Adefovir Dipivoxil When Added to Standard Antiretroviral Therapy for the Treatment of HIV-Infected Patients With CD4 Cell Counts >= 200/mm3

HIV Infections

United States
Agouron Pharmaceuticals

Completed

A Study of Viracept in AIDS Patients With Cytomegalovirus Retinitis

HIV Infections | Cytomegalovirus Retinitis

United States
Anderson Clinical Research
Ligand Pharmaceuticals

Completed

A Study of ALRT1057 in Patients With AIDS-Related Kaposi's Sarcoma

HIV Infections | Sarcoma, Kaposi
Glaxo Wellcome

Completed

A Comparison of Two Multi-Drug Therapies in HIV-Infected Patients Who Have Never Received Anti-HIV Treatment

HIV Infections

United States
Merck Sharp & Dohme LLC
Agouron Pharmaceuticals

Completed

A Study on the Safety and Effectiveness of Twice-Daily Nelfinavir Plus Twice-Daily Indinavir Plus Efavirenz in HIV-Positive Patients Who Have Never Taken Non-Nucleoside Reverse Transcriptase Inhibitors (NNRTIs) or Protease Inhibitors

HIV Infections

United States
Pharmacia and Upjohn

Completed

A Study to Find the Best Dosing Schedule for Delavirdine, Zidovudine, and Indinavir in HIV-Positive Patients

HIV Infections

United States
Lederle Laboratories

Completed

A Multi-Center, Open-Label, Ascending, Multiple Oral Dose, Safety, Tolerance and Pharmacokinetic Study of 3'-Deoxy-3'-Fluorothymidine (FLT) in Patients With Acquired Immune Deficiency Syndrome (AIDS) or AIDS-Related Complex (ARC)

HIV Infections

United States
Stolle Milk Biologic International

Completed

The Effectiveness of Cow's Milk Immune Globulin in the Treatment of AIDS-Related Diarrhea

HIV Infections | Cryptosporidiosis

United States
Glaxo Wellcome

Completed

The Safety and Effectiveness of Retrovir in HIV-Infected Patients Who Have Problems Related to the Nervous System

HIV Infections

United States
LyphoMed

Completed

A Study of Two Forms of Pentamidine in the Treatment of Pneumocystis Carinii Pneumonia (PCP) in Patients With AIDS

HIV Infections | Pneumonia, Pneumocystis Carinii

United States
Pharmacia and Upjohn

Completed

The Safety and Effectiveness of U-90152 in HIV-1 Infected Patients Who Take Zidovudine

HIV Infections

United States
Gilead Sciences

Completed

The Safety and Effectiveness of Bis-POM PMEA in HIV-Infected Patients

HIV Infections

United States
Apollon

Completed

A Phase I Trial of APL 400-003 Vaccine: Safety and Immune Response Evaluations of Multiple Injections at Escalating Doses in Asymptomatic HIV-Infected Patients

HIV Infections

United States
Hoechst Marion Roussel

Completed

The Safety and Effectiveness of HBY 097 Used With or Without AZT in HIV-Infected Patients Who Have Mild or No Symptoms

HIV Infections

United States
Triangle Pharmaceuticals

Suspended

A Comparison of Emtricitabine and Abacavir Used in a Three-Drug Combination in HIV-Infected Patients Who Have Never Taken Anti-HIV Drugs

HIV Infections

United States
Hoffmann-La Roche

Completed

A Comparison of Three Anti-HIV Drug Combinations Containing Saquinavir Soft Gelatin Capsules Used in HIV-1 Infected Patients

HIV Infections

United States, Puerto Rico, Spain, Germany, Italy, United Kingdom
Gilead Sciences

Unknown

The Safety and Effectiveness of PMPA Prodrug in HIV-Infected Patients

HIV Infections

United States
National Center for Research Resources (NCRR)
Roberts Pharmaceutical

Completed

Phase II Study of Midodrine for Neurogenic Orthostatic Hypotension

Orthostatic Hypotension

United States
National Center for Research Resources (NCRR)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); University...

Completed

Phase I Study of Retrovirally Mediated Transfer of the Human Glucocerebrosidase Gene Into Peripheral Blood Stem Cells for Autologous Transplantation in Patients With Type I Gaucher Disease

Gaucher's Disease

United States
National Center for Research Resources (NCRR)
Oregon Health and Science University

Terminated

Study of Dietary N-3 Fatty Acids in Patients With Retinitis Pigmentosa and Usher Syndrome

Retinitis Pigmentosa | Usher Syndrome

United States
National Center for Research Resources (NCRR)
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) and other collaborators

Completed

Phase II Study of Recombinant Relaxin for Progressive Systemic Sclerosis

Systemic Sclerosis
National Center for Research Resources (NCRR)
University of North Carolina

Completed

Phase I Study of Human Von Willebrand Factor for Von Willebrand's Disease

Von Willebrand's Disease
National Center for Research Resources (NCRR)
Virginia Commonwealth University

Completed

Study of Individualized Instruction Versus Pamphlet in Systemic Lupus Erythematosus

Systemic Lupus Erythematosus
National Center for Research Resources (NCRR)
Northwestern University

Completed

Phase II Randomized Study of Cidofovir for Peripheral Cytomegalovirus Retinitis

Acquired Immunodeficiency Syndrome | Cytomegalovirus Retinitis
Glaxo Wellcome

Completed

Safety and Effectiveness of a Combination Anti-HIV Drug Treatment

HIV Infections

United States
National Center for Research Resources (NCRR)

Unknown

Hormone Replacement Therapy and Insulin Action: A Double-Blind, Parallel, Placebo-Controlled Hormone Intervention Study in Postmenopausal Women

Menopause

United States
National Center for Research Resources (NCRR)
Indiana University School of Medicine

Unknown

Study of Total Energy Expenditure in Infants and Children With Moderate to Severe Cystic Fibrosis

Cystic Fibrosis

United States
Hoffmann-La Roche
Trimeris

Completed

T-20 With Anti-HIV Combination Therapy for Patients With Prior Anti-HIV Drug Treatment and/or Drug Resistance to Each of the Three Classes of Approved Anti-HIV Drugs

HIV Infections

United States, Canada
Fred Hutchinson Cancer Center

Completed

Phase I Pilot Study of Total-Body Irradiation, Anti-Thymocyte Globulin and Cyclophosphamide Followed By Syngeneic or Autologous Peripheral Blood Stem Cell Transplantation in Patients With Multiple Sclerosis

Multiple Sclerosis

United States
National Center for Research Resources (NCRR)
Centers for Disease Control and Prevention

Unknown

Intensive Pharmacokinetics of the Nelfinavir-Rifabutin Interaction in Patients With HIV-Related Tuberculosis Treated With a Rifabutin-Based Regimen

HIV Infections | Tuberculosis

United States
Corixa Corporation

Completed

Safety and Efficacy Study of Iodine-131 Anti-B1 Antibody Plus CHOP For Untreated Mantle Cell Lymphoma

Mantle Cell Lymphoma

United States
GMP Endotherapeutics

Completed

Single Dose and 34-Day Tolerance Study of INGAP Peptide in Insulin Deficient Patients

Diabetes Mellitus, Type 2 | Diabetes Mellitus, Type 1

United States
Genelabs Technologies

Unknown

Study of GL701 in Men With Systemic Lupus Erythematosus

Systemic Lupus Erythematosus

United States

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