Search clinical trials for: Long-term Safety

Total 45489 results

Grupo Portugues de Estudo do Cancro do Pulmao

Unknown

Efficacy and Safety of Cetuximab in Combination With Cisplatin Gemcitabine as First-Line Therapy in Advanced NSCLC (Coimbra)

Carcinoma, Non-Small-Cell Lung

Portugal
Keio University

Terminated

Safety and Efficacy Study of Salvage Chemotherapy (R-ESHAP) to Treat Relapsed and Refractory Aggressive Non-Hodgkin's Lymphoma

Lymphoma, Non-Hodgkin

Japan
National Institute of Allergy and Infectious Diseases...
Johns Hopkins Bloomberg School of Public Health

Completed

Single Group Study of the Safety of and Immune Response to a Bird Flu Virus Vaccine (H5N1) in Healthy Adults

Virus Diseases | Influenza

United States
Eli Lilly and Company

Completed

Investigation of the Efficacy and Safety of Drotrecogin Alfa (Activated) in Pediatric Severe Sepsis

Sepsis

United States, United Kingdom, France, Slovakia, Switzerland, Australia, Poland, Italy, Chile, Germany, Mexico
DNP Canada
JSS Medical Research Inc.

Completed

Efficacy and Safety of HEP-40 Chitosan for Mild to Moderately Elevated Cholesterol (HEP-40)

Hypercholesterolemia

Canada
Pfizer

Completed

A Study Comparing The Efficacy & Safety Of Torcetrapib/Atorvastatin And Atorvastatin In Subjects With High Triglycerides

Hypertriglyceridemia | Hyperlipoproteinemia Type IV

United States, Canada
French National Agency for Research on AIDS and...
Hoffmann-La Roche

Completed

Efficacy and Safety of Addition of IL-2 to Pegylated Interferon Alpha 2a and Ribavirin in HIV/HCV Coinfected Patients

HIV Infections | Chronic Hepatitis C

France
Medicure

Completed

A Safety and Efficacy Study to Confirm the Cardioprotective Effects of MC-1 in Patients Undergoing High-Risk CABG

Myocardial Ischemia | Reperfusion Injury | Coronary Artery Bypass Graft Surgery

Canada, United States
Baxter Healthcare Corporation

Completed

Performance and Safety of Bone Substitute MBCP-FS in Maxillary Sinus Lift Procedures

Sinus Implant Reconstruction

Germany
University Hospital, Basel, Switzerland

Completed

Dental Safety Profile of High-Dose Radioiodine Therapy

Thyroid Cancer

Switzerland
Karolinska Institutet
Karolinska University Hospital

Completed

Safety Study of Pelvic Organ Prolapse Repair Using Transvaginal Mesh

Pelvic Organ Prolapse

Sweden, Norway, Denmark, Finland
Solvay Pharmaceuticals

Completed

Study to Evaluate the Efficacy and Safety of Daglutril Compared to Placebo on Top of Losartan in Type 2 Diabetics With Overt Nephropathy and Well Controlled Hypertension

Hypertension

Italy
GP-Pharm

Completed

Leuprolide Acetate 3.75 mg Depot to Treat Prostate Cancer

Prostate Cancer

United States, Austria, Czech Republic, Germany, Hungary, Italy, Slovakia, Spain, United Kingdom
JADO Technologies GmbH

Completed

Efficacy and Safety of TF002 in Cutaneous Mastocytosis

Cutaneous Mastocytosis

Germany
United Therapeutics

Terminated

Transitioning To IV Remodulin From Ventavis in Patients With PAH: Safety, Efficacy and Treatment Satisfaction

Hypertension, Pulmonary

United States
Sinovac Biotech Co., Ltd
Centers for Disease Control and Prevention, China

Completed

Safety and Immunogenicity of an Inactivated Pandemic Influenza Vaccine

Prevention | Pandemic Influenza
Encysive Pharmaceuticals

Completed

Safety and Efficacy Study of Sitaxentan Sodium (Thelin™) in Patients With Pulmonary Arterial Hypertension

Pulmonary Hypertension

United States
Tri-Service General Hospital

Unknown

A Pilot Study to Evaluate the Safety and Activities of EW02 in Reducing Neutropenia Caused by Chemotherapy

Breast Cancer | Neutropenia | Chemotherapy

Taiwan
Pfizer

Terminated

[S,S]-Reboxetine Long Term Safety Study In Post-Shingles Pain.

Pain

Canada, United States, India, Chile, Mexico, Spain, United Kingdom, Croatia, Argentina, Lithuania, Poland, Sweden
OccuLogix

Suspended

Safety and Effectiveness Investigation for Dry, Non-Exudative Age Related Macular Degeneration (AMD) Using Rheopheresis (RHEO-AMD)

Age-Related Maculopathy

United States, Germany, Canada
Eli Lilly and Company
ICOS Corporation

Completed

A Study to Evaluate the Efficacy and Safety of 2.5mg and 5mg Tadalafil Given Once a Day to Men With Erectile Dysfunction

Erectile Dysfunction

United States
Medical Research Foundation, The Netherlands
Medtronic

Completed

Accuracy and Safety of Real Time Continuous Glucose Monitoring Before, During and After Surgery (GluContinu)

Glucose Metabolism Disorders | Perioperative Care

Netherlands
InterMune

Completed

An Open-Label Study of the Safety and Efficacy of Subcutaneous Recombinant Interferon-Gamma 1b (IFN-Gamma 1b) in Patients With Idiopathic Pulmonary Fibrosis (IPF)

Pulmonary Fibrosis | Lung Disease

United States
FibroGen

Completed

A Randomized Study of the Safety and Efficacy of FG-2216 in Subjects With Renal Anemia Not Requiring Dialysis and Not Receiving Recombinant Human Erythropoietin

Renal Anemia

United States
InterMune

Completed

A Study of the Safety and Clinical Effects of Interferon Gamma-1b in Patients With Idiopathic Pulmonary Fibrosis (IPF)

Idiopathic Pulmonary Fibrosis

United States
Eli Lilly and Company

Completed

Extension Study on Safety of Long-Term Growth Hormone Replacement in Adult Patients With Growth Hormone Deficiency

Adult Growth Hormone Deficiency

Japan
Abbott

Withdrawn

A Dose-Finding Study to Evaluate the Safety, Efficacy and Pharmacokinetics of Adalimumab in Subjects With Refractory Asthma

Asthma
InterMune

Terminated

A Randomized, Double-Blind, Three-Arm, Phase 3b Study Comparing the Safety and Efficacy of Interferon Gamma-1b With Azathioprine, and Azathioprine Alone in Patients With IPF Receiving Prednisone

Pulmonary Fibrosis | Lung Disease

Italy
Eli Lilly and Company

Completed

Efficacy and Safety of Once-Daily Atomoxetine Hydrochloride in Adults With ADHD Over an Extended Period of Time (6 Months)

ADHD

United States
Hadassah Medical Organization
XTL Biopharmaceuticals

Withdrawn

Safety, Tolerability and Efficacy of XTL 2125 in HCV-Infected Patients Who Are Interferon-Alpha Non-Responders or Relapsers

Chronic Hepatitis C Virus Infection

Israel
InterMune

Terminated

An Open-Label Study of the Safety of Interferon Gamma-1b in Patients With IPF

Idiopathic Pulmonary Fibrosis | Pulmonary Fibrosis | Lung Disease

United States
New River Pharmaceuticals

Completed

Safety, Tolerability and Abuse Liability Study of Intravenous NRP104 in Adults With Stimulant Abuse Histories

Substance-Related Disorders | Attention Deficit Disorder With Hyperactivity | Amphetamine-Related Disorders

United States
New River Pharmaceuticals

Completed

Study to Evaluate the Likeability, Safety, and Abuse Potential of NRP 104 in Adults With Histories of Stimulant Abuse

Substance-Related Disorders | Attention Deficit Disorder With Hyperactivity | Amphetamine-Related Disorders

United States
Validus Pharmaceuticals

Completed

Safety of SPD417 Combined With Other Psychotropic Medications in the Treatment of Bipolar I Disorder

Bipolar Disorder
InterMune

Completed

A Study of the Safety and Efficacy Interferon-Gamma 1b in Patients With Idiopathic Pulmonary Fibrosis (IPF)

Idiopathic Pulmonary Fibrosis

United States
Hospital Israelita Albert Einstein
Fundação de Amparo à Pesquisa do Estado de São Paulo

Completed

Efficacy and Safety of Three Insulin Protocols in Medical Intensive Care Unit Patients

Intensive Care

Brazil
Validus Pharmaceuticals

Completed

Efficacy and Safety of SPD417 in Treatment of Manic Symptoms in Adults With Bipolar I Disorder

Bipolar Disorder
InterMune

Terminated

Safety of Interferon Gamma-1b With Rituximab in Non-Hodgkin's Lymphoma Patients

Non-Hodgkin's Lymphoma

United States
InterMune

Completed

Safety and Efficacy Study of Interferon Gamma-1b in Hepatitis C Patients With Liver Fibrosis or Cirrhosis

Cirrhosis | Liver Fibrosis
Beth Israel Medical Center

Terminated

Assessing the Efficacy and Safety of Rosiglitazone Added to Standard Therapy for Hepatitis C Genotype 1 With Fatty Liver

Fatty Liver | Chronic Hepatitis C Infection

United States
InterMune

Terminated

Safety and Efficacy of Interferon Gamma-1b Plus Chemotherapy for Ovarian and Peritoneal Cancer

Peritoneal Carcinoma | Ovarian Carcinoma

United States
InterMune

Terminated

Safety and Efficacy of Inhaled Interferon Gamma-1b in Pulmonary MAC Infection

Lung Infection
Pfizer

Completed

Study To Evaluate The Safety And Efficacy Of Torcetrapib/Atorvastatin In Subjects With Familial Hypercholerolemia

Hyperlipidemia | Hypercholesterolemia, Familial

Australia, Canada, United States, France, South Africa, Sweden, Norway, Denmark, Iceland
Speedel Pharma Ltd.

Completed

Phase IIa Safety and Efficacy Study of SPP635 in Mild to Moderate Hypertension

Hypertension

Germany
Neovii Biotech

Completed

Safety and Efficacy Study With Catumaxomab in Patients After Curative Resection of a Gastric Adenocarcinoma

Gastric Cancer | Gastric Adenocarcinoma

Germany
Eli Lilly and Company
ICOS Corporation

Completed

Efficacy and Safety of Tadalafil in Subjects With Erectile Dysfunction Caused by Spinal Cord Injury

Erectile Dysfunction | Spinal Cord Injuries

United States
National Institute of Allergy and Infectious Diseases...

Completed

Safety of and Immune System Response to an HIV Vaccine (EP HIV-1090) in HIV Infected Patients

HIV Infections

United States
Queen Elizabeth II Health Sciences Centre

Unknown

The Safety and Immunogenicity of Acellular Pertussis Vaccine in Bone Marrow Transplant Recipients

Pertussis
Eli Lilly and Company
ICOS Corporation

Completed

To Determine Effect and Safety of Tadalafil Taken by Men of Different Races and With Different Diseases When Needed for Erections

Impotence

United States
Eli Lilly and Company
ICOS Corporation

Completed

Determine Safety and Effectiveness of Tadalafil in Asian Men When Taken as Needed for Getting and Keeping an Erection

Impotence

China

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