Search clinical trials for: 5-HT3 antagonist

Total 38815 results

Janssen-Cilag International NV

Completed

A Study of Relapse Prevention and the Effectiveness of Long-acting Injectable Risperidone and Quetiapine Tablets in the Treatment of Patients With Schizophrenia or Schizoaffective Disorder

Psychotic Disorders | Schizophrenia

France, Poland, Germany, Spain, Slovenia, Bulgaria, Romania, Israel, Greece, Sweden, Turkey, Czech Republic, Hungary, Lithuania, Latvia, Portugal, Croatia, Slovakia, Austria, United Kingdom, Estonia, Ireland, Denmark, Saudi Arabia
Otsuka Pharmaceutical Development & Commercialization...

Completed

Aripiprazole in Adolescents With Schizophrenia (APEX 239)

Schizophrenia

United States, Puerto Rico
National Institute of Mental Health (NIMH)

Completed

Sequenced Treatment Alternatives to Relieve Depression (STAR*D)

Depression

United States
Gruppo Italiano Studio Linfomi

Completed

Study With Palonosetron Alone in Preventing Chemotherapy-induced Nausea and Vomiting in Untreated Patients With Aggressive Non Hodgkin's Lymphomas Who Underwent Moderately Emetogenic Chemotherapy (NHLPal)

Non Hodgkin's Lymphoma | Chemotherapy-Induced Nausea and Vomiting

Italy
Arena Pharmaceuticals

Completed

A Multiple-Dose Study to Assess the Safety, Tolerability, and Steady State Pharmacokinetics of APD791 in Healthy Volunteers

Healthy

United States
University Hospital Tuebingen

Completed

Examination of the Lipid Metabolism of the Liver After Choline Substitution in Cystic Fibrosis

Cystic Fibrosis Liver Disease
H. Lundbeck A/S

Completed

Vortioxetine Intravenous Infusion at Initiation of Oral Treatment With Vortioxetine in Patients With Depression

Major Depressive Disorder

Bulgaria, Estonia, Latvia
Takeda

Completed

Effect of Vortioxetine, Paroxetine, and Placebo on Sexual Functioning in Healthy Volunteers

Healthy Volunteers

United States
Otsuka Pharmaceutical Development & Commercialization...

Completed

A Trial to Assess a Wearable Patch's Functioning to Detect Medication Ingestion

Schizophrenia | Major Depressive Disorder | Mental Disorder | Bipolar I Disorder

United States
VA Office of Research and Development

Withdrawn

VA Aripiprazole vs Esketamine for Treatment Resistant Depression (VAST-D II)

Depressive Disorder, Major

United States
Vanguard Research Group
Otsuka America Pharmaceutical

Completed

Comparison of a Long-acting Injectable Antipsychotic vs Clinician's Choice Early in Treatment to Break the Cycle of Relapse in Early Phase Schizophrenics (PRELAPSE)

Schizophrenia

United States
Otsuka Pharmaceutical Development & Commercialization...

Terminated

A Trial to Measure the Difference in All-cause Hospitalizations for Participants Who Are Using Abilify MyCite Versus Virtual Matched Controls in Adults With Schizophrenia, Bipolar 1 Disorder, and Major Depressive Disorder

Schizophrenia | Major Depressive Disorder | Bipolar 1 Disorder

United States
Seoul National University Hospital
Otsuka Pharmaceutical Co., Ltd.

Completed

Aripiprazole (Abilify®) as an Adjunctive Treatment for Inadequate Response in Major Depressive Disorder

Major Depressive Disorder

Korea, Republic of
Wei Hao

Terminated

A Comparison of Risperidone and Aripiprazole for Treatment of Patirnts With Methamphetamine-Associated Psychosis

Methamphetamine Dependence

China
Otsuka Pharmaceutical Co., Ltd.

Completed

Study of Aripiprazole as an Adjunctive Therapy in Patients With Major Depressive Disorder

Major Depressive Disorder

Japan
National Taiwan University Hospital
Yu-Li Hospital; Yu-Li Veterans Hospital

Completed

Identification and Treatment Response Prediction of Antipsychotic-Related Metabolic Syndrome

Metabolic Syndrome X

Taiwan
Scotmann Pharmaceuticals
Rawalpindi Medical College

Not yet recruiting

Vortioxetine as a Novel Anti-depressant With Improvement in Cognitive Abilities (VENUS)

Major Depressive Disorder
H. Lundbeck A/S

Completed

Investigating the Effect of Vortioxetine in Adult ADHD Patients

Attention Deficit Hyperactivity Disorder

United States
State University of New York - Downstate Medical...

Completed

Examining the Effect of Ondansetron on Bowel Prep Success

Abdominal Pain | Diarrhea | Inflammatory Bowel Diseases | Weight Loss | Eosinophilic Gastroenteritis | Hematochezia

United States
University of Leeds
University College London Hospitals; The Leeds Teaching Hospitals NHS Trust; Sheffield... and other collaborators

Completed

TReatment of Irritable Bowel Syndrome With Diarrhoea Using Titrated ONdansetron Trial (TRITON)

IBS - Irritable Bowel Syndrome

United Kingdom
Yonsei University

Completed

Comparison of Palonosetron and Ramosetron for Preventing Patient-controlled Analgesia Related Nausea and Vomiting Following Spine Surgery; Association With ABCB1 Polymorphism

Postoperative Nausea and Vomiting

Korea, Republic of
Eisai Inc.
Helsinn Healthcare SA

Completed

Safety and Efficacy Study for the Prevention of Nausea and Vomiting in Multiple Myeloma Patients Receiving Stem Cell Transplantation.

Multiple Myeloma

United States
Shanghai Changzheng Hospital
JiangSu Chia-Tai Tianqin Pharmacy Co.Ltd

Completed

Efficacy and Safety of Palonosetron Hydrochloride in the Prevention of Nausea and Vomiting (ESPNV)

Neoplasms | Chemotherapy-Induced Nausea and Vomiting

China
Instituto Nacional de Cancer, Brazil

Completed

Compare Between Two Doses of Palonosetron on the Prevention of Postoperative Nausea and Vomiting in Obese Patients

Postoperative Nausea and Vomiting

Brazil
M.D. Anderson Cancer Center
Eisai Inc.

Completed

Palonosetron for Prevention of Biochemotherapy Induced Nausea and Vomiting

Melanoma

United States
Arena Pharmaceuticals

Completed

Single-Dose Safety Study of APD791 in Healthy Volunteers

Healthy

United States
Second Affiliated Hospital, School of Medicine,...

Not yet recruiting

Efficacy and Safety of Intravenous Versus Oral 5-HT3 Antagonists Combined With NK-1 Receptor Antagonists for the Prevention of CINV in Breast Cancer

Breast Cancer | Chemotherapy-induced Nausea and Vomiting

China
Chonnam National University Hospital

Recruiting

Psychopharmacotherapy for Depressive Patients (BMDD-2022)

Major Depressive Disorder

Korea, Republic of
Centre for Addiction and Mental Health
Janssen Inc.

Recruiting

Risk of Breakthrough Symptoms With Long-Acting Injectable Medications

Schizophrenia | Schizophrenia Relapse

Canada
University of California, Los Angeles
Alkermes, Inc.

Terminated

Aripiprazole Lauroxil for Preventing Psychotic Relapse After an Initial Schizophrenia Episode (APPRAISE)

Schizophrenia | Schizophreniform Disorder | Schizoaffective Disorder, Depressive Type

United States
Future University in Egypt

Completed

Bioequivalence Study of Aripiprazole in Healthy Adult Subjects Under Fasting Condition

Healthy Subjects

Egypt
Alkermes, Inc.

Completed

A Study of Aripiprazole Lauroxil or Paliperidone Palmitate for the Treatment of Schizophrenia

Schizophrenia

United States
University of British Columbia
Bristol-Myers Squibb

Completed

Comparison of Aripiprazole Versus Higher Metabolic Risk Antipsychotic Drugs on Adiposity Using MRI (CALM)

Psychotic Disorders | Bipolar Disorder | Metabolic Syndrome X

Canada
Bangabandhu Sheikh Mujib Medical University, Dhaka...

Recruiting

Mirtazapine Versus Megestrol Acetate in Treatment of Anorexia-cachexia in Advanced Cancer Patients.

Anorexia

Bangladesh
San Francisco Department of Public Health
University of California, Los Angeles

Recruiting

Mirtazapine and Methamphetamine Drug-drug Interaction Study

Cardiovascular Abnormalities | Methamphetamine Use Disorder | Drug Interaction

United States
University of Sao Paulo

Completed

Comparison Between Mirtazapine and Megestrol for the Control of Anorexia-cachexia in Cancer Patients in Palliative Care.

Anorexia | Cachexia; Cancer

Brazil
University of Calgary

Recruiting

A Proof of Principle Study of Ondansetron for the Prevention of Vasovagal Syncope: The Eleventh Prevention of Syncope Trial (POST11) (POST 11)

Syncope | Vasovagal Syncope (VVS)

Canada
Yung Shin Pharm. Ind. Co., Ltd.

Completed

Evaluate Bioequivalence of Palonosetron (0.25mg/5mL)

Chemotherapy-induced Nausea and Vomiting, Prophylaxis

Taiwan
Joseph Ma

Terminated

Combination of Netupitant and Palonosetron (Akynzeo®) in the Treatment of Refractory CINV (CINV)

Chemotherapy Induced Nausea Vomiting
Hangzhou Jiuyuan Gene Engineering Co. Ltd.,
Sun Yat-sen University; Tigermed Consulting Co., Ltd

Completed

Safety and Efficacy of Palonosetron in Preventing Chemotherapy-induced Nausea and Vomiting

Nausea | Vomiting | Chemotherapy

China
Otsuka Pharmaceutical Co., Ltd.

Completed

Bioequivalence Between Single Administration of ASC-01 (Aripiprazole/Sertraline Combination Drug) and Concomitant Single Administration of Aripiprazole and Sertraline, and Food Effect on Pharmacokinetics of ASC-01 in Healthy Male Adults

Healthy Male Adults

Japan
UMC Utrecht

Completed

European Long-acting Antipsychotics in Schizophrenia Trial (EULAST)

Schizophrenia

Netherlands, Norway, Austria, Belgium, Bulgaria, Czechia, Denmark, Germany, Greece, Hungary, Israel, Italy, Poland, Romania, Spain, United Kingdom
Northwell Health

Terminated

1/2-MC4R Genotype and Pediatric Antipsychotic Drug- Induced Weight Gain

High Risk MC4R Genotype | Low Risk MC4R Genotype | One Week or Less Antipsychotic Lifetime Exposure

United States
Otsuka Pharmaceutical Development & Commercialization...
Otsuka America Pharmaceutical

Completed

Aripiprazole Used as Dual Therapy in the Treatement of Patients With Chronic Stable Schizophrenia or Schizoaffective Disorder.

Schizophrenia | Schizoaffective Disorder

United States
Korea Otsuka Pharmaceutical Co., Ltd.

Completed

Abilify in Bipolar Disorder for 24 Weeks Treatment Effectiveness (SMART-M)

Bipolar Disorder

Korea, Republic of
Korea Otsuka Pharmaceutical Co., Ltd.

Completed

Abilify in Bipolar Disorder for 6 Weeks Treatment Effectiveness (SMART-A)

Bipolar Disorder

Korea, Republic of
First Affiliated Hospital of Chongqing Medical...
Southwest Hospital, China; Central South University; The Second Affiliated Hospital... and other collaborators

Recruiting

Sequenced Treatment Alternatives to Relieve Adolescent Depression (STAR-AD) (STAR-AD)

Depression | Sequestra

China
Linkoeping University

Completed

Serum Concentrations of Antidepressant Drugs in Pregnant Women - a Naturalistic Study (PAPA)

Pregnancy | Pharmacokinetics | Antidepressive Agents

Sweden
Capital Medical University

Completed

Effectiveness Study of Mirtazapine Combined With Paroxetine in Major Depressive Patients Without Early Improvement

Major Depression

China
Shanghai Mental Health Center

Completed

a Pilot Study of Pramipexole to Treat Extrapyramidal Symptoms Induced by Antipsychotics

Extrapyramidal Syndrome

China

Search clinical trials for: 5-HT3 antagonist

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