Search clinical trials for: CNTO 148

Total 4641 results

AltruBio Inc.

Completed

Neihulizumab (ALTB-168) in Patients With Steroid-refractory Acute Graft-versus-host Disease or Treatment-refractory Acute Graft-versus-host Disease

Steroid-refractory Acute Graft-versus-Host Disease | Treatment-refractory Acute Graft-versus-Host Disease

United States
Sagimet Biosciences Inc.

Active, not recruiting

Open-label Study of the Absorption, Metabolism, and Excretion of [14C]TVB-2640 Following a Single Oral Dose in Healthy Male Subjects

Healthy Volunteers

United States
TenNor Therapeutics Limited

Completed

Absorption, Metabolism, and Excretion Study of [14C]-TNP-2092

Healthy

United States
Pyramid Biosciences

Completed

A Phase 1 Study of the Absorption, Metabolism, and Excretion of [14C] PBI-200

Absorption, Metabolism and Excretion in Healthy Volunteers

United States
Jiangsu HengRui Medicine Co., Ltd.

Completed

A Study of Human Substance Balance and Biotransformation of [14C]SHR0302

Rheumatoid Arthritis (RA)

China
Senju Pharmaceutical Co., Ltd.
Quotient Sciences

Completed

Single Dose ADME Study of [14C]SJP-0008 in Healthy Male Subjects

Healthy Volunteers

United Kingdom
Spectrum Pharmaceuticals, Inc

Terminated

A Mass Balance and Pharmacokinetics Study of 14C-Labeled Poziotinib in Cancer Patients Suitable for Treatment With Poziotinib

Solid Tumor

United States
Eisai Limited

Completed

A Study to Determine the Metabolism and Elimination of [14C]E7090 in Healthy Male Participants

Healthy Volunteers

United Kingdom
Perosphere Pharmaceuticals Inc, a wholly owned...
World Wide Clinical Trials Early Phase Services, LLC

Completed

An Open-label, Single-dose, Non-randomized Study of IV 14C-labeled PER977 in Healthy Male Subjects

Healthy

United States
Advanced Accelerator Applications

Terminated

99mTc-rhAnnexin V-128 in Diagnosis of Spondyloarthritis (Annexin 03)

Spondyloarthritis

United States
Eli Lilly and Company

Completed

A Study of LY3214996 in Healthy Participants

Healthy

United States
Entasis Therapeutics

Completed

Study to Determine the Excretion and Metabolism of 14C-ETX2514 Administered Intravenously in Healthy Male Subjects

Acinetobacter Baumannii-calcoaceticus Complex Infections

United States
Eli Lilly and Company

Completed

Study of LY3154207 in Healthy Participants

Healthy

United States
Balance Therapeutics

Completed

A Study to Investigate the Mass Balance of BTD-001 (HV103)

Molecular Mechanisms of Pharmacological Action

United Kingdom
Massachusetts General Hospital

Completed

XL184 For Relapsed/Refractory Multiple Myeloma (MM) With Bone Disease

Multiple Myeloma

United States
Massachusetts General Hospital
Exelixis

Completed

Cabozantinib (XL-184) Monotherapy for Advanced Cholangiocarcinoma

Bile Duct Cancer | Intrahepatic Cholangiocarcinoma | Cholangiocarcinoma of the Extrahepatic Bile Duct

United States
Bioprojet

Completed

Study to Assess the Absorption, Distribution, Metabolism and Excretion (ADME) of [14C]-Pitolisant in Healthy Male Volunteers

Healthy Volunteers
Pfizer

Completed

A Study To Investigate The Absorption, Distribution, Metabolism, And Excretion Of [14c]PF-06463922 In Healthy Male Volunteers

Healthy

United States
Pfizer

Completed

A Study To Understand How Radiolabelled PF-04449913 Is Taken Up By The Body, Broken Down And Then Removed From The Body

Healthy

United States
Ono Pharmaceutical Co. Ltd

Completed

A Human Mass Balance Study to Determine the Total Recovery of Radioactivity in Urine and Faeces Following a Single Oral Dose of 14C Radiolabelled ONO-4053

Healthy Adult Male Subjects

United Kingdom
Dow Pharmaceutical Sciences

Completed

Safety and Efficacy of Topical IDP-108 Versus Vehicle in Patients With Onychomycosis

Onychomycosis

United States, Canada, Japan
Takeda

Completed

A Study to Assess the Relative Bioavailability and to Assess the Effect of Food on the Bioavailability of a TAK-648 Tablet in Healthy Participants

Healthy Volunteers

United States
Eisai Limited

Completed

A Study to Determine the Absolute Bioavailability and the Absorption, Metabolism, and Elimination Properties of Carbon-14 (14C)E7386 in Healthy Male Participants

Healthy Volunteers

United Kingdom
Immune-Onc Therapeutics

Recruiting

Dose Confirmation and Dose Expansion Phase 1 Study of IO-108 and IO-108 + Anti-PD-1 in Solid Tumors

Advanced Solid Tumor

China
Changchun GeneScience Pharmaceutical Co., Ltd.
Syneos Health

Recruiting

A Study to Assess Safety and Tolerability of GS1-144 in Healthy Volunteers

Vasomotor Symptoms | Adult Healthy Volunteers

Australia
Vertex Pharmaceuticals Incorporated

Recruiting

Phase 2/3 Adaptive Study of VX-147 in Adult and Pediatric Participants With APOL1- Mediated Proteinuric Kidney Disease Mediated Proteinuric Kidney Disease (AMPLITUDE)

Proteinuric Kidney Disease

United States, Spain, Ghana, France, United Kingdom, Belgium, Brazil, Colombia, Portugal, Canada, Puerto Rico, Netherlands
Bausch Health Americas, Inc.

Recruiting

A Safety and Pharmacokinetics Study of IDP-118 Lotion in Pediatric Participants With Plaque Psoriasis

Psoriasis

United States, Panama
Vertex Pharmaceuticals Incorporated

Completed

Evaluation of the Pharmacokinetics and Safety of VX-548 in Participants With Renal Impairment

Pain

United States
Eli Lilly and Company

Active, not recruiting

A Study of Carbon-14-Labelled [14C] LY3473329 in Healthy Male Participants

Healthy

United Kingdom
Eli Lilly and Company

Completed

A Phase I Study of LY3502970 in Healthy Participants

Healthy

United States
Vertex Pharmaceuticals Incorporated

Completed

A Study to Evaluate the Relative Bioavailability and Food Effect of a New Tablet Formulation of VX-548

Pain

United States
Vertex Pharmaceuticals Incorporated

Completed

Evaluation of the Pharmacokinetics and Safety of VX-548 in Participants With Mild or Moderate Hepatic Impairment

Pain

United States
Jacobio Pharmaceuticals Co., Ltd.

Completed

Mass Balance Study of [14C]JAB-21822

Mass Balance Study in Healthy Subjects

China
Artax Biopharma Inc
Simbec-Orion Group

Completed

A Study of the Safety, Tolerability, Pharmacokinetics and Food Effect After Single and Multiple Ascending Oral Doses

Autoimmune Diseases

United Kingdom
Taisho Pharmaceutical Co., Ltd.

Completed

Clinical Study of TS-143 in Healthy Adult Male Subjects (Single-Dose Administration)

Healthy Participants

Japan
Shandong Luoxin Pharmaceutical Group Stock Co.,...

Completed

Mass Balance and Biotransformation Study of [14C]LXI-15028 in Humans

Healthy Subjects | Pharmacokinetics of 14C-labeled of LXI-15028

China
Sunshine Lake Pharma Co., Ltd.

Completed

ADME Study of [14C] Antaitavir Hasophate in Healthy Male Subjects

Healthy Male Subjects

China
Taisho Pharmaceutical Co., Ltd.

Completed

Clinical Study of TS-143 in Healthy Adult Male Subjects (Multiple-Dose Administration)

Healthy Participants

Japan
Gesynta Pharma AB
Ergomed

Completed

A Study to Investigate Safety of GS-248 and Efficacy on Raynauds' Phenomenon in Systemic Sclerosis

Systemic Sclerosis

United Kingdom, Poland, Belgium, Netherlands
iTeos Belgium SA

Completed

First-In-Human Study of EOS884448 in Participants With Advanced Cancers.

Advanced Cancer

Belgium
H. Lundbeck A/S

Completed

A Study Investigating Lu AG06466 in Healthy Men

Healthy Volunteers

United Kingdom
SecuraBio

Terminated

A Phase 1 Study of Duvelisib in Patients With Advanced Hematologic Malignancies

Hematologic Malignancies

United States
Millennium Pharmaceuticals, Inc.

Completed

A Study to Evaluate the Mass Balance, Pharmacokinetics (PK), Metabolism and Excretion of TAK-954 Containing Microtracer ([14C]-TAK-954) in Healthy Male Participants

Healthy Volunteers

Netherlands
Poxel SA

Completed

Pharmacokinetics and Metabolism of (14C)-Labelled PXL770

Healthy

United Kingdom
University of California, Los Angeles
Massachusetts General Hospital; Washington University School of Medicine; University... and other collaborators

Completed

A Multicenter Study of NAP (AL-108) in Schizophrenia (AL-108)

Schizophrenia

United States
Sanwa Kagaku Kenkyusho Co., Ltd.

Completed

A Study to Assess the Mass Balance Recovery, Metabolite Profile and Metabolite Identification of [14C]-SK-1405

Pruritus

United Kingdom
ViiV Healthcare
GlaxoSmithKline

Withdrawn

A Study to Investigate the Recovery, Excretion, and Pharmacokinetics of 14C-GSK2248761 Administered as an Oral Suspension to Healthy Adult Subjects

Infection, Human Immunodeficiency Virus

United States
Allon Therapeutics

Completed

Safety, Tolerability and Efficacy Study to Evaluate Subjects With Mild Cognitive Impairment

Mild Cognitive Impairment, So Stated

United States
Dow Pharmaceutical Sciences

Completed

The Safety and Efficacy of Topical IDP-108 Versus Vehicle in Patients With Onychomycosis

Onychomycosis

United States, Canada
LG Life Sciences

Completed

Study in Healthy Male Subjects Designed to Assess the Mass Balance Recovery, Metabolite Profile and Metabolite Identification of [14C] LC15-0444

Healthy

Korea, Republic of

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