Search clinical trials for: CRS

Total 1208 results

International Partnership for Microbicides, Inc.
National Institute of Allergy and Infectious Diseases (NIAID)

Completed

Safety and Pharmacokinetics of Dapivirine Vaginal Ring in Post-menopausal Women

Human Immunodeficiency Virus

United States
Bayer

Completed

A Study to Learn How the Study Treatment BAY1753011 Moves Into, Through and Out of the Body, How it Works, How Safe it is, and How it Affects the Body When Given Once as Tablet in Male and Female Participants With Reduced Kidney Function Compared to Matched Participants With Normal Kidney Function

Renal Impairment | Congestive Heart Failure

Germany
Pfizer

Completed

A Trial To Assess The Safety, Tolerability, And Immunogenicity Of Rlp2086 Vaccine When Administered In Either 2- Or 3-Dose Regimens In Healthy Subjects Aged ≥11 To <19 Years

Meningococcal Vaccine

Spain, Germany, Finland, Czechia, Poland, Denmark, Sweden
International Partnership for Microbicides, Inc.
National Institutes of Health (NIH); Microbicide Trials Network

Completed

Study of Dapivirine Vaginal Ring (VR) in Adolescents

Human Immunodeficiency Virus

United States
AbbVie

Completed

Study to Evaluate the Safety and How the Body Handles a Single Dose of Subcutaneous (SC) and Intravenous (IV) Budigalimab in Adult Participants Living With Human Immunodeficiency Virus (HIV)

Human Immunodeficiency Virus (HIV)

United States, Puerto Rico
National Institute of Allergy and Infectious Diseases...
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Completed

Study of Effects of Tenofovir on Bone Health and Kidneys During Pregnancy and Breastfeeding

HIV Infections

Malawi, South Africa, Zimbabwe, Uganda
Université de Sherbrooke

Terminated

Mometasone vs Budesonide in CRS With Polyposis

Chronic Rhinosinusitis (Diagnosis), Nasal Polyposis

Canada
BioNTech SE

Completed

A Trial Investigating the Safety and Effects of One or Two Additional Doses of Comirnaty or One Dose of BNT162b2s01 in BNT162-01 or BNT162-04 Trial Subjects

COVID-19 | SARS-CoV-2 Infection

Germany
HIV Prevention Trials Network

Completed

The ADAPT Study: Use of Emtricitabine and Tenofovir Disoproxil Fumarate for Pre-Exposure Prophylaxis (PrEP) (ADAPT)

HIV Infections

United States, South Africa, Thailand
Boehringer Ingelheim

Completed

This Study in Healthy Men Tests How Different Doses of BI 705564 Are Taken up in the Body and How Well They Are Tolerated. The Study Also Tests How BI 705564 Affects the Way the Body Breaks Down Midazolam

Healthy

Germany
Boehringer Ingelheim

Completed

A Study in Men With Overweight to Test How Well Different Doses of BI 1820237 Are Tolerated When Given as an Injection Alone or in Combination With Liraglutide

Healthy

Germany
HIV Prevention Trials Network
National Institute of Allergy and Infectious Diseases (NIAID)

Completed

The Women's HIV SeroIncidence Study (ISIS)

HIV Infections

United States
Bayer

Completed

Study on the Safety of the Drug BAY2395840 at Different Doses, the Way the Body Absorbs, Distributes and Excretes the Drug Including the Effect of Its Formulation (Tablet or Liquid) and the Effect of Food on the Absorption, Distribution or Excretion of the Drug in Healthy Male Participants

Endometriosis

Germany
HIV Prevention Trials Network
National Institute of Allergy and Infectious Diseases (NIAID)

Completed

Enhancing Recruitment, Linkage to Care and Treatment for HIV-Infected MSM in the United States

HIV

United States
HIV Prevention Trials Network

Completed

Preparing for International Prevention Trials Involving HIV-Infected Individuals in Care Settings (HPTN063)

HIV

Brazil, Thailand, Zambia
HIV Prevention Trials Network
National Institute on Drug Abuse (NIDA); National Institute of Allergy and... and other collaborators

Completed

Feasibility Study of a Multi-Component Intervention for Black Men Who Have Sex With Men

HIV Infections

United States
National Institute of Allergy and Infectious Diseases...

Completed

Safety of and Immune Response to a Prime-Boost Vaccine Regimen in HIV-Uninfected Vaccine-Naive Adults

HIV Infections

United States, Peru
National Institute of Allergy and Infectious Diseases...
HIV Vaccine Trials Network

Completed

Safety of and Immune Response to a DNA HIV Vaccine (pGA2/JS7) Boosted With a Modified Vaccinia HIV Vaccine (MVA/HIV62) in Healthy Adults

HIV Infections

United States
National Institute of Allergy and Infectious Diseases...

Completed

Evaluating the Immunogenicity of the AIDSVAX B/E Vaccine and the MVA/HIV62B Vaccine in Healthy, HIV-1-Uninfected Adults Who Previously Received MVA/HIV62B in DNA/MVA or MVA/MVA Regimens in HVTN 205

HIV Infections

United States, Peru
Wits Health Consortium (Pty) Ltd
Fred Hutchinson Cancer Center; Janssen Vaccines & Prevention B.V.; National Institute... and other collaborators

Completed

Sisonke (Together): OPEN LABEL TRIAL COVID-19 (Sisonke)

SARS (Severe Acute Respiratory Syndrome)

South Africa
COVID-19 Prevention Network
National Institute of Allergy and Infectious Diseases (NIAID)

Completed

A Study of Immune Responses to the Virus That Causes COVID-19 (CoVPN 5001)

COVID-19 | SARS-CoV-2

United States, Malawi, Zimbabwe, Botswana, South Africa, Zambia, Argentina, Brazil, Mexico, Peru, Tanzania
Provention Bio, Inc.

Completed

PROtocol for Coxsackievirus VaccinE in Healthy VoluNTteers (PROVENT)

Viral; Infection, Coxsackie(Virus)

Finland
National Institute of Allergy and Infectious Diseases...
Eunice Kennedy Shriver National Institute of Child Health and Human Development...

Completed

Pharmacokinetic Study of Antiretroviral Drugs and Related Drugs During and After Pregnancy

HIV Infections

United States, Puerto Rico, Thailand, Botswana, Argentina, Brazil, Tanzania, South Africa
Centre for Infectious Disease Research in Zambia
Göteborg University; European and Developing Countries Clinical Trials Partnership... and other collaborators

Completed

An Epidemiological Surveillance Study to Determine the Incidence of ETEC in Children and Infants in Lusaka (ETEC-Surv)

Diarrhea Toddlers | Escherichia Coli Diarrhea

Zambia
Boehringer Ingelheim

Terminated

Evaluation of Safety and Tolerability of Single Rising Doses of BI 473494 in Healthy Subjects

Healthy

Germany
Orion Corporation, Orion Pharma

Completed

Study to Compare Relative Bioavailability of 3 Indacaterol/Glycopyrronium Test Products and Reference Product (FORELLI)

Healthy Volunteers

Finland
National Institute of Allergy and Infectious Diseases...

Completed

Evaluating the Safety, Tolerability, Pharmacokinetics, and Antiviral Activity of Combinations of Monoclonal Antibodies PGT121, PGDM1400, 10-1074, and VRC07-523LS Administered Via Intravenous Infusion in Healthy, HIV-uninfected Adult Participants

HIV Infections

United States
St. Paul's Hospital, Canada

Withdrawn

Efficacy of Budesonide Via Delayed Release vs Immediate Release

Chronic Rhinosinusitis (Diagnosis)
National Institute of Allergy and Infectious Diseases...

Completed

Evaluating the Safety and Immunogenicity of an HIV-1 gp41 MPER-656 Liposome Vaccine in Healthy, HIV-uninfected Adult Participants

HIV Infections

United States
Janssen-Cilag International NV

Terminated

A Study of Orally Administered Pimodivir in Adult Participants With Renal Impairment

Kidney Failure, Chronic

Germany
IRIS Media Inc
Spelman College

Completed

Culturally Responsive Stress Reduction: A Mobile Mindfulness Application for African Americans (CRSR) (CRSR)

Behavior

United States
Noveome Biotherapeutics, formerly Stemnion
IQVIA Biotech

Completed

Safety and Tolerability Study of IV ST266 in COVID-19 Subjects

Cytokine Release Syndrome

United States
Idorsia Pharmaceuticals Ltd.

Completed

Effect of Cimetidine on the Pharmacokinetics of Lucerastat in Healthy Subjects

Healthy Subjects

Germany
Bayer

Completed

A Trial to Learn What Happens to Different Medicinal Forms of BAY2328065 When They Enter the Body and How Safe They Are in Healthy Male and Female Participants

Endometriosis

Germany
HIV Vaccine Trials Network
National Institute of Allergy and Infectious Diseases (NIAID); HIV Prevention...

Completed

Characterizing SARS-CoV-2-specific Immunity in Individuals Who Have Recovered From COVID-19

COVID-19 | SARS-CoV-2

United States, Zimbabwe, Malawi, Peru, South Africa, Zambia
Sisli Hamidiye Etfal Training and Research Hospital

Enrolling by invitation

Does Epidural Anesthesia Reduce Postoperative Ileus Following Colorectal Surgery?

Colorectal Disorders | Postoperative Ileus

Turkey
Boehringer Ingelheim

Completed

A Study in Healthy Men to Test How Well Different Doses of BI 1819479 Are Tolerated and Taken up by the Body With or Without Food

Healthy

Germany
Idorsia Pharmaceuticals Ltd.

Completed

A Study to Investigate the Effect of Single and Repeated Oral Doses of ACT-539313 on What the Body Does to Flurbiprofen, Omeprazole, Midazolam in Healthy Subjects

Healthy

Germany
National Institute of Allergy and Infectious Diseases...

Completed

Pharmacokinetic and Safety Study of a 90 Day Intravaginal Ring Containing Tenofovir

HIV Infections

United States
National Institute of Allergy and Infectious Diseases...

Completed

Evaluating the Safety and Immunogenicity of HIV Clade C DNA Vaccine and MF59- or AS01B-Adjuvanted Clade C Env Protein Vaccines in Various Combinations in Healthy, HIV-Uninfected Adults

HIV Infections

United States, South Africa
National Institute of Allergy and Infectious Diseases...

Completed

HIV-1-Gag Conserved-Element DNA Vaccine (p24CE) Vaccine Study

HIV Infections

United States, Puerto Rico
National Institute of Allergy and Infectious Diseases...

Completed

Evaluating the Safety and Immunogenicity of Env (A,B,C,A/E)/Gag (C) DNA and gp120 (A,B,C,A/E) Protein/GLA-SE HIV Vaccines, Given Individually or Co-administered, in Healthy, HIV-1-Uninfected Adults

HIV Infections

United States
National Institute of Allergy and Infectious Diseases...

Completed

Evaluating the Infectivity, Safety, and Immunogenicity of Recombinant Live-Attenuated RSV Vaccines RSV ΔNS2/Δ1313/I1314L or RSV 276 in RSV-Seronegative Infants 6 to 24 Months of Age

Respiratory Syncytial Virus Infections

United States
National Institute of Allergy and Infectious Diseases...

Completed

Integrase and Maraviroc Intensification in Neurocognitive Dysfunction (InMIND)

HIV Infections

United States, Puerto Rico, Thailand, South Africa, Brazil
HIV Vaccine Trials Network

Completed

An Observational Study of Long-term Outcomes of HIV-1 Infection in Persons Who Become HIV-1 Infected After Enrollment in HIV-1 Vaccine Trials

HIV Infections

United States, Dominican Republic, Haiti, Peru, Puerto Rico, South Africa
Pari Pharma GmbH

Completed

Buparid/PARI SINUS Versus Budes® Nasal Spray in the Therapy of Chronic Rhinosinusitis

Rhinosinusitis

Germany
Pari Pharma GmbH

Completed

Buparid/PARI SINUS Versus Budes® Nasal Spray in the Therapy of Chronic Rhinosinusitis With Polyposis Nasi

Rhinosinusitis | Chronic Polyposis

Germany
Boehringer Ingelheim

Completed

This Study Tests the Safety, Tolerability and How Different Doses of BI 1265162 Are Taken up in the Body of Healthy Men

Healthy

Germany
Florida State University
Johns Hopkins University; Children's Hospital of Philadelphia; University of... and other collaborators

Completed

Tailored Motivational Interviewing Implementation-Effectiveness Trial in Multidisciplinary Adolescent HIV Care Settings (TMI)

HIV Infections | Adolescent Development | Care Eliciting Behavior | Patient Non-Compliance | Patient Refusal of Treatment

United States
Pharm-Olam, LLC
Biomedical Advanced Research and Development Authority

Terminated

Specimen Collection Study From Coronavirus Disease 2019 (COVID-19) Vaccinated Adults and Adolescents (CoVacSpec)

COVID-19

United States, South Africa, Colombia, Guadeloupe, India, Mexico, Puerto Rico

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