Search clinical trials for: Endothelin-1

Total 47379 results

University of Southern Denmark
Region of Southern Denmark; Danish Council for Independent Research; The Faculty...

Completed

Genetic Variation in Organic Cation Transport 1 (OCT1) and Its Significance for Morphine Pharmacokinetics

Morphine | Organic Cation Transporter 1

Denmark
São Paulo State University

Completed

Muscular Resistance Test in the Elastic Tube: Reliability and Training of the Proposed Method

Muscle Strength Quantitative Trait Locus 1

Brazil
Actelion

Completed

Open-label Study With Bosentan in Interstitial Lung Disease (BUILD 2 OL)

Interstitial Lung Disease | Scleroderma

United States, Korea, Republic of, Israel, France, United Kingdom, Netherlands, Switzerland, Germany, Canada, Italy, Sweden
General Hospital of Chalkida

Unknown

Bosentan for Severe Mitral Valve Dysfunction (BOSMIVAR)

SECONDARY PULMONARY HYPERTENSION | MITRAL STENOSIS | CHILDHOOD RHEUMATOID FEVER | CONGESTIVE HEART FAILURE

Greece
Actelion

Completed

Open Label Extension Study in Patients With Idiopathic Pulmonary Fibrosis Who Completed Protocol AC-052-321/ BUILD 3 / NCT00391443 (BUILD OL)

Idiopathic Pulmonary Fibrosis

United States, France, Spain, Korea, Republic of, United Kingdom, Belgium, Japan, Australia, Canada, Czech Republic, Germany, Ireland, Israel, Italy, Switzerland
Actelion

Completed

Bosentan in Patients With Inoperable Chronic Thromboembolic Pulmonary Hypertension (CTEPH) (BENEFIT OL)

Pulmonary Hypertension

United States, Canada, Australia, Germany, Italy, United Kingdom, France, Austria, Belgium, Czech Republic, Netherlands, Poland, Spain
Medical University of Graz
Actelion

Completed

Early Therapy of Pulmonary Arterial Hypertension

Systemic Sclerosis | Pulmonary Hypertension

Austria
Japan Clinical Oncology Group
Ministry of Health, Labour and Welfare, Japan

Terminated

Elderly NSCLC/D vs DP (JCOG0207)

Non-small-cell Lung Cancer

Japan
Japan Clinical Oncology Group
Taiho Pharmaceutical Co., Ltd.; Ministry of Health, Labour and Welfare, Japan; Yakult Honsha Co., LTD

Completed

A Study of 5-FUci Versus CPT-11 Plus CDDP Versus S-1 Alone in Advanced Gastric Cancer

Gastric Cancer

Japan
Japan Clinical Oncology Group
Ministry of Health, Labour and Welfare, Japan

Completed

Trial of Drainage With or Without Bleomycin Instillation for Malignant Pericardial Effusion

Malignant Pericardial Effusion

Japan
Federal State Budgetary Institution National Medical...
Kemerovo Cardiology Center, Tarasov Roman Sergeevich; Tomsk National Research...

Recruiting

Management Tactics for Patients High Risk With Acute Coronary Syndrome Without ST Segment Elevation and Multivessel Coronary Artery Disease (NSTE-ACSMT)

Coronary Syndrome, Acute, Non-ST Elevation, High Risk Patients

Russian Federation
McGill University
Super Sublime | Super Splendide; Résidences Enharmonie

Completed

The Effects of a Nature-Based Mindfulness-Compassion Intervention for Older Adults Delivered Using Virtual Reality

Healthy Aging | Mental Health Wellness 1

Canada
Abramson Cancer Center of the University of Pennsylvania

Completed

A Study of the Communication of Genetic Test Results By Telephone: A Multi-Center Study

Candidates for BRCA 1/2 Genetic Testing

United States
CorStone
David and Lucile Packard Foundation

Active, not recruiting

Youth First: A Longitudinal Impact Evaluation

Mental Health Wellness 1 | Resilience, Psychological

India
Takeda

Completed

Adherence to PTH(1-84) Treatment (FP-002-IM)

Clinical Use of PTH(1-84)

Denmark
Vanderbilt University
National Institute of Mental Health (NIMH); Leon Lowenstein Foundation Inc.

Completed

Effects of Routine Feedback to Clinicians on Youth Mental Health Outcomes: A Randomized Cluster Design

Mental Health Wellness 1 | Psychosocial Problem

United States
ByHeart

Enrolling by invitation

Multi-Center Clinical Database of Infants for the Investigation of Early Nutrition Biomarkers

Infant Development

United States
Istanbul Medeniyet University

Not yet recruiting

Using Machine Learning to Detect Risky Behavior in Psychiatric Clinics

Machine Learning | Dangerous Behavior

Turkey
Muğla Sıtkı Koçman University

Recruiting

Subacromial Impingement Syndrome Functional Tests Correlation With Ultrasound Parameters

Subacromial Impingement Syndrome | Shoulder Pain | Shoulder Bursitis | Shoulder Tendinitis

Turkey
VistaGen Therapeutics, Inc.
Parexel

Recruiting

AV-101 Alone and in Combination With Probenecid in Healthy Subjects

Drug Drug Interaction

United States
DiaSorin Inc.
ICON Clinical Research

Completed

Helicobacter Pylori Sample Collection Protocol Pre Therapy Subjects

Nausea | Abdominal Pain | Weight Loss | Helicobacter Pylori Infection | Gastric Ulcer | Stomach Ulcer | Loss of Appetite | Bloating

United States, Italy
Boston University Charles River Campus
Massachusetts General Hospital; University of Illinois at Chicago; Utah State...

Recruiting

Leadership, Engagement, and Youth Activism Program With Mindfulness (LEAP)

Mental Health Wellness 1 | Adolescent Behavior

United States
University of Southern Denmark

Completed

Inter- and Intra-individual Variations in Metformin Pharmacokinetics - The Importance of Genes and Drug Interactions

Metformin | Organic Cation Transporter 1 | Codeine

Denmark
OPKO Health, Inc.
Elan Pharmaceuticals

Terminated

Safety and Efficacy Study of ELND005 as an Adjunctive Maintenance Treatment in Bipolar I Disorder

Bipolar 1 Disorder

United States, Bulgaria, Canada, Czechia, France, Poland, Romania, Spain, Turkey
The University of Hong Kong

Completed

Intervention for Abused Chinese Immigrant Women

Mental Health Wellness 1 | Domestic Violence

China
Bispebjerg Hospital
University of Copenhagen; Duke University; The Ministry of Science, Technology... and other collaborators

Completed

Impact of CES1 Genotype on Metabolism of Methylphenidate

Carboxylesterase 1 (CES1) Genotype | CES1 Activity

Denmark
University of Glasgow
Scottish Collaboration for Public Health Research and Policy

Completed

Mellow Bumps RCT - Antenatal Intervention for Vulnerable Women

Pregnancy | Mental Health Wellness 1 | Mother-Child Relations

United Kingdom
The N.1 Institute for Health (N.1)
Manjusri Secondary School, Singapore

Not yet recruiting

Implementing Digital Peer Support Training for Adolescent Mental Health

Mental Health Wellness 1 | Peer Group | Adolescent Development
Heinrich-Heine University, Duesseldorf

Completed

Effect of Bosentan on Skin Fibrosis in Patients With Systemic Sclerosis

Systemic Scleroderma | Skin Fibrosis | Hand Functionality

Germany
Rajan Saggar
Actelion

Withdrawn

Pulmonary Arterial Hypertension Secondary to Idiopathic Pulmonary Fibrosis and Treatment With Bosentan

Idiopathic Pulmonary Fibrosis | Pulmonary Arterial Hypertension

United States
ELIAS Emergency University Hospital

Recruiting

Evaluating the Efficacy and Quality of Life Impact of Transitioning to Advanced Hybrid Closed-Loop Insulin Pump Therapy in Romanian Children With Type 1 Diabetes Mellitus

Diabetes Mellitus, Type 1

Romania
B.P. Koirala Institute of Health Sciences

Unknown

Work-Site Intervention Study to Prevent Diabetes in Nepal (WSS)

Diabetes

Nepal
Mekelle University

Completed

Effect of Community-Based Interventions on Increasing Family Planning Utilization in Pastoralist Community

Family Size

Ethiopia
Zealand University Hospital

Suspended

Microfracture in Rotator Cuff Injury Repair

Rupture of the Rotator Cuff

Denmark
Unilever R&D

Completed

The Effect of a Natural Extract on Glucose Fluxes After Consumption of a Wheat Product

Healthy

Netherlands
Merck KGaA, Darmstadt, Germany
Merck N.V.-S.A., Belgium

Terminated

An Observational Study to Compare the Dose of Gonal-fTM FbM Prescribed by the Doctor With the Recommendation of the Dose Calculator Consort and to Evaluate the Ease of Use of Pre-filled Pen of Gonal-fTM FbM Pen

Multifollicular Stimulation

Belgium
Unilever R&D

Completed

Effect of Different Flour Compositions in a Carbohydrate-based Food on Rate of Exogenous Glucose Appearance in Blood

Healthy

Netherlands
Karolinska Institutet
The Swedish Research Council; Actelion; Swedish Heart Lung Foundation

Completed

Effect of Bosentan on Endothelial Function in Patients With Type 2 Diabetes (BANDY)

Type 2 Diabetes Mellitus

Sweden
Actelion

Completed

Bosentan Effects in Inoperable Forms of Chronic Thromboembolic Pulmonary Hypertension

Chronic Thromboembolic Pulmonary Hypertension

Canada, Australia, Germany, United States, Italy, United Kingdom, Austria, Belgium, Czech Republic, France, Netherlands, Poland, Spain
Actelion

Completed

Bosentan in Systemic Sclerosis (HOME)

Systemic Sclerosis | Digital Ulcers

Netherlands
Actelion

Terminated

Efficacy and Safety of Bosentan in Sickle Cell Disease (SCD) Patients Diagnosed With Pulmonary Hypertension (PH) (ASSET-2)

Pulmonary Hypertension

United States, France, United Kingdom, Netherlands
Hamilton Health Sciences Corporation
Actelion

Unknown

A Study to Evaluate the Use of Bosentan in Patients With Exercise Induced Pulmonary Arterial Hypertension Associated With Connective Tissue Disease

Hypertension, Pulmonary | Connective Tissue Disease

Canada
National Institute of Nursing Research (NINR)

Not yet recruiting

A Natural History Study of RYR1-Related Disorders

Ryanodine Receptor 1-Related Myopathy | Ryanodine Receptor 1 Related Disorders

United States
Zigong No.1 Peoples Hospital

Recruiting

Correlation Between Deep Medullary Veins and Cognitive Dysfunction in Cerebral Small Vessel Disease

Cerebral Small Vessel Disease

China
Studio 1 Labs
York University

Completed

Functional Bed Sheet Capturing Pressure Variation and Respiratory Effort Over Time

Apnea | Respiration

Canada
Yangzhou No.1 People's Hospital

Unknown

Comparison of Detection and Miss Rates of Blue Laser Imaging Versus Conventional White Light Colonoscopy

Colorectal Adenoma

China
University Hospital No 1 Wroclaw

Unknown

Efficacy of Zinc Sulfate With Probiotics for the Treatment of Acute Diarrhea in Children (Zinc)

Acute Watery Diarrhoea

Poland
Eli Lilly and Company

Completed

A Study of Tirzepatide (LY3298176) in Healthy Lactating Females

Healthy

United States
PharmaMar

Recruiting

Study to Evaluate the Effect of Bosentan on the Pharmacokinetics of Lurbinectedin in Patients With Advanced Solid Tumors

Advanced Solid Tumor

Spain
Actelion

Completed

Pulmonary Artery Remodelling With Bosentan

Hypertension, Pulmonary

Australia

Search clinical trials for: Endothelin-1

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