Search clinical trials for: High dose Methotrexate

Total 39251 results

Fudan University

Recruiting

R-CDOP Combined With Intrathecal Methotrexate for DLBCL Patients With High-risk of CNS Relapse

Diffuse Large B-cell Lymphoma

China
Fondazione Italiana Linfomi - ETS

Recruiting

Consolidation With Loncastuximab Tesirine After a Short Course of Immunochemotherapy in BTKi-treated (or Intolerant) Relapsed/Refractory Mantle Cell Lymphoma Patients. (FIL_COLUMN)

Refractory Mantle Cell Lymphoma | Relapsed Mantle Cell Lymphoma

Italy
Peking Union Medical College Hospital

Recruiting

Dexmedetomidine and Sufentanil Effect in PCA on Pediatric Patients Undergoing Scoliosis Surgery (DEX)

Dexmedetomidine

China
Southern Methodist University
National Cancer Institute (NCI); University of Kansas Medical Center; University...

Recruiting

Factorial Trial Testing Guided Thinking Tasks to Optimize a Physical Activity Intervention

Physical Inactivity

United States
Beijing InnoCare Pharma Tech Co., Ltd.

Recruiting

A Study to Evaluate the Efficacy and Safety of Orelabrutinib in Adult Patients With Immune Thrombocytopenia

Primary Immune Thrombocytopenia

China
Ankara City Hospital Bilkent

Not yet recruiting

Comparison of Sugammadex and Sugammadex-neostigmine Combination in the Antagonism of Moderate Neuromuscular Block

Residual Neuromuscular Block | Neuromuscular Blockade Monitoring

Turkey
Anhui Medical University

Recruiting

Accelerated Continue Theta-burst Stimulation (acTBS)Treatment for Obsessive Compulsive Disease

Transcranial Magnetic Stimulation | Obsessive-Compulsive Disorder | Functional Magnetic Resonance Imaging | Accelerated Continue Theta-burst Stimulation

China
Vanderbilt University Medical Center
University of Alabama at Birmingham; Duke University; University of Washington; Northwestern University Feinberg School of Medicine

Recruiting

High vs. Standard Dose Influenza Vaccine in Lung Allograft Recipients

Influenza | Transplantation Infection | Immunization; Infection

United States
Shanghai Henlius Biotech

Not yet recruiting

A Study to Evaluate the Efficacy and Safety of HLX07 in nsqNSCLC Patients With High EGFR Expression

HLX07, nsqNSCLC, High EGFR Expression

China
Dalin Tzu Chi General Hospital

Recruiting

Effects of Herbal Sleep Formula on Patients With Insomnia and Tinnitus

Tinnitus | Sleep Disturbances

Taiwan
University Hospital, Montpellier

Recruiting

Prevalence of High Plasmatic 3OMethyldopa Level in a Specific Population of Patients With a Symptomatology Compatible With AADC Deficiency (DOPADEF)

Aromatic L-Amino Acid Decarboxylase Deficiency

France
Ocugen

Recruiting

Study to Assess the Safety and Efficacy of OCU400 for Retinitis Pigmentosa and Leber Congenital Amaurosis (OCU400)

Retinitis Pigmentosa | Leber Congenital Amaurosis

United States
University Hospital, Brest

Recruiting

AVAJAK: Apixaban/Rivaroxaban Versus Aspirin for Primary Prevention of Thrombo-embolic Complications in JAK2V617F-positive Myeloproliferative Neoplasms (AVAJAK)

Polycythemia Vera | Essential Thrombocythemia | High-risk Patients | Prefibrotic/Early Primary Myelofibrosis | JAK2 V617F

France
Kaohsiung Medical University

Recruiting

14-day PCAB-based High-dose Dual Therapy and14-day PCAB-based Triple Therapy vs 14-day PPI-based Reverse Hybrid Therapy

Helicobacter Pylori Eradication

Taiwan
Yale University

Recruiting

IV Pulsed-Nicotine as a Model of Smoking: The Effects of Dose and Delivery Rate

Nicotine Dependence

United States
Medical University of Warsaw

Recruiting

Induction of Sustained Unresponsiveness to Peanuts Using High- and Low-dose Peanut Oral Immunotherapy

Peanut Allergy

Poland
Hanyang University Seoul Hospital
Linical Korea

Not yet recruiting

REduCed Dose of TNFi in Patients With Ankylosing SpondyliTis (RECAST)

Ankylosing Spondylitis | Axial Spondyloarthritis
Transdermal Delivery Solutions Corp
Langford Research Institute, Inc.

Not yet recruiting

Dose Response Study of Transdermal Human Insulin in Patients (LEVPS)

Glucose, High Blood

United States
Medical University of Warsaw

Recruiting

High and Low Dose Oral Sesame Immunotherapy - Comparison of Efficacy and Safety (Sesame)

Food Allergy

Poland
Yantai Yuhuangding Hospital

Recruiting

Study of Decompensated Alcoholic Cirrhosis Treatment by Stem Cells

Alcoholic Cirrhosis

China
Yantai Yuhuangding Hospital

Recruiting

Clinical Study of Allergic Rhinitis Therapy by Stem Cells

Allergic Rhinitis

China
National Cancer Institute (NCI)
Childrens Oncology Group (COG); LLS PedAL LLC

Recruiting

Highest Dose of Uproleselan in Combination With Fludarabine and Cytarabine for Patients With Acute Myeloid Leukemia, Myelodysplastic Syndrome, or Mixed Phenotype Acute Leukemia Relapsed or Refractory and That Expresses E-selectin Ligand on the Cell Membrane

Down Syndrome | Recurrent Acute Myeloid Leukemia | Recurrent Myelodysplastic Syndrome | Refractory Acute Myeloid Leukemia | Refractory Myelodysplastic Syndrome | Recurrent Mixed Phenotype Acute Leukemia | Refractory Mixed Phenotype Acute Leukemia | Acute Myeloid Leukemia Post Cytotoxic Therapy | Myelodysplastic...

United States
Sidney Kimmel Comprehensive Cancer Center at Johns...

Recruiting

Intraoperative Radiation Therapy After Stereotactic Body Radiation Therapy and Chemotherapy in Treatment of Pancreatic Adenocarcinoma

Pancreatic Cancer

United States
City of Hope Medical Center
National Cancer Institute (NCI)

Recruiting

Multiple Doses of Neural Stem Cell Virotherapy (NSC-CRAd-S-pk7) for the Treatment of Recurrent High-Grade Gliomas

Recurrent Glioblastoma | Recurrent Malignant Glioma | Recurrent WHO Grade III Glioma | Recurrent WHO Grade II Glioma | Recurrent Gliosarcoma | Recurrent Anaplastic Astrocytoma | Recurrent Anaplastic Oligoastrocytoma | Recurrent Anaplastic Oligodendroglioma

United States
Shanghai Zhongshan Hospital
Shanghai Changzheng Hospital

Recruiting

Selenious Yeast in CLL Patients w/o Indication of Chemotherapy

Chronic Lymphocytic Leukemia Stage A(0) | Chronic Lymphocytic Leukemia Stage A(I) | Chronic Lymphocytic Leukemia Stage A(II) | Chronic Lymphocytic Leukaemia Stage B(I)

China
Tianjin Medical University General Hospital

Recruiting

Esketamine vs. Ketorolac for Prevention of Postoperative Pain and Cognitive Dysfunction After Total Knee Arthroplasty

Postoperative Pain | Postoperative Cognitive Dysfunction | Total Knee Arthroplasty

China
Makerere University

Recruiting

Pharmacogenetics-guided Isoniazid Dosing in TB-HIV (PHINX)

Tuberculosis

Uganda
The Aurum Institute NPC
Johns Hopkins University

Recruiting

Comparing Treatment Completion Of Daily Rifapentine & Isoniazid For One Month (1HP) To Weekly High Dose Rifapentine & Isoniazid For 3 Months (3HP) In Persons Living With HIV and in Household Contacts of Recently Diagnosed Tuberculosis Patients (1 to 3)

Tuberculosis | HIV Seropositivity | Household Contact

South Africa, India, Indonesia, Mozambique
Guardant Health, Inc.

Recruiting

Screening for High Frequency Malignant Disease (SHIELD)

Lung Cancer

United States, France, Spain
HK inno.N Corporation

Recruiting

Study to Evaluate the Safety and Immunogenicity of SARS-CoV-2 Vaccine (IN-B009) in Healthy Adults (COVID-19)

COVID-19

Korea, Republic of
Ain Shams University

Recruiting

High Dose Methylprednisolone Verses Low Dose in Correction of Congenital Acynotic Heart Disease

Anesthesia

Egypt
Peter Kovacs MD

Recruiting

Cumulative Pregnancy Rate With Lower and Higher Gonadotropin Dose During IVF Among Poor Responders

Infertility | Ovarian Dysfunction

Hungary
Hospital da Senhora da Oliveira

Recruiting

Comparison Between High-dose Amoxicillin Dual Therapy and Pylera Quadruple Therapy in the Treatment of Helicobacter Pylori Infection

Gastritis | Gastric Cancer | Helicobacter Pylori Infection

Portugal
Supernus Pharmaceuticals, Inc.
Solstice Neurosciences

Not yet recruiting

Efficacy and Safety Study of MYOBLOC® in the Treatment of Sialorrhea in Pediatric Subjects

Sialorrhea
Barcelona Institute for Global Health
Centro de Investigação em Saúde de Manhiça; Medicines for Malaria Venture; University... and other collaborators

Recruiting

MULTIple Doses of IPTi Proposal: a Lifesaving High Yield Intervention (MULTIPLY)

Malaria

Sierra Leone, Mozambique, Togo
Erasme University Hospital
Jules Bordet Institute; University Hospital St Luc, Brussels; Belgian Group of...

Recruiting

Preoperative mFOLFIRINOX (or Gem-Nab-P) +/- Isotoxic High-dose SBRT for Borderline Resectable Pancreatic Adenocarcinoma (STEREOPAC)

Pancreatic Adenocarcinoma | Borderline Resectable Pancreatic Adenocarcinoma | Pancreatic Neoplasm

Belgium
Brigham and Women's Hospital
University of Cape Town; APIN Public Health Initiatives

Recruiting

Dolutegravir Pharmacokinetics Among HIV/TB Coinfected Children Receiving Standard and High-dose Rifampicin

Tuberculosis Infection | Pediatric HIV Infection

Nigeria
Biogen

Recruiting

A Study to Evaluate Higher Dose (HD) Nusinersen (BIIB058) in Participants With Spinal Muscular Atrophy Previously Treated With Risdiplam (ASCEND)

Spinal Muscular Atrophy

United States, Germany, Italy, Hungary, Japan
The Second Hospital of Anhui Medical University

Recruiting

Effect of Intravenous S-ketamine on Opioid Consumption

Breast Cancer Surgery

China
M.D. Anderson Cancer Center

Recruiting

High Dose-Rate Brachytherapy for the Treatment of Both Primary and Secondary Unresectable Liver Malignancies

Melanoma | Pancreatic Cancer | Cholangiocarcinoma Metastatic | Liver Malignant Tumors

United States
NRG Oncology
National Cancer Institute (NCI)

Recruiting

Comparing High-Dose Cisplatin Every Three Weeks to Low-Dose Cisplatin Weekly When Combined With Radiation for Patients With Advanced Head and Neck Cancer

Advanced Head and Neck Squamous Cell Carcinoma | Squamous Cell Carcinoma of Unknown Primary | Advanced Hypopharyngeal Squamous Cell Carcinoma | Advanced Laryngeal Squamous Cell Carcinoma | Advanced Oropharyngeal Squamous Cell Carcinoma

United States, Canada
National Institute of Allergy and Infectious Diseases...
National Institutes of Health (NIH); Janssen, LP

Recruiting

An Evaluation of Repeated Oral Doses of JNJ-64281802 Against DENV-3 Challenge

Dengue

United States
Biruni University

Recruiting

High-dose, Short-term Steroid and Low-dose Long-term Steroid Use in ARDS Caused by COVID-19

Short-term (3 Days) High-dose (1000 mg) Systemic Methylprednisolone

Turkey
Fundação de Medicina Tropical Dr. Heitor Vieira...
Bill and Melinda Gates Foundation; Conselho Nacional de Desenvolvimento Científico...

Recruiting

Study to Evaluate Primaquine for Radical Cure of Uncomplicated Plasmodium Vivax Malaria in Children (CHILDPRIM)

Malaria, Vivax

Brazil
Copenhagen Studies on Asthma in Childhood

Recruiting

High-dose Vitamin D Supplement for the Prevention of Acute Asthma-like Symptoms in Preschool Children (COPSACvitd)

Asthma in Children

Denmark
J.M. de Laat
Radboud University Medical Center; University Medical Center Groningen; Maastricht... and other collaborators

Recruiting

Precision Radiotherapy Using MR-linac for Pancreatic Neuroendocrine Tumours in MEN1 Patients (PRIME)

Multiple Endocrine Neoplasia Type 1 | Neuroendocrine Tumor of Pancreas

Netherlands
Ilocos Training and Regional Medical Center

Not yet recruiting

Effectiveness Of High Dose Melatonin As Adjunctive Therapy For Dengue Fever With Warning Signs

Dengue Fever With Warning Signs
M.D. Anderson Cancer Center

Recruiting

Tagraxofusp and Low-Intensity Chemotherapy for the Treatment of CD123 Positive Relapsed or Refractory Acute Lymphoblastic Leukemia or Lymphoblastic Lymphoma

Recurrent Adult Lymphoblastic Lymphoma | Recurrent B Acute Lymphoblastic Leukemia | Refractory B Acute Lymphoblastic Leukemia | Refractory T Acute Lymphoblastic Leukemia | Recurrent T Acute Lymphoblastic Leukemia | Refractory Lymphoblastic Lymphoma

United States
Hugo Galindo

Not yet recruiting

High-dose Intravenous Vitamin C (HDIVC) as Adjuvant Therapy in Critical Patients With Positive COVID-19. A Pilot Randomized Controlled Dose-comparison Trial. (HDIVC)

Covid19
Taipei Veterans General Hospital, Taiwan

Not yet recruiting

Higher Dose of Alglucosidase Alpha for Pompe Disease

Glycogen Storage Disease Type II

Search clinical trials for: High dose Methotrexate

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Cote d'Ivoire

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations