Search clinical trials for: IDH Mutant
Total 796 results
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ETOP IBCSG Partners FoundationAmgen; Eisai Inc.WithdrawnMetastatic Non Small Cell Lung Cancer | KRAS G12CSpain, Switzerland, Austria, Germany
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Institut de Recherches Internationales ServierActive, not recruitingLeukemia, Myeloid, Acute | Untreated AML | Newly Diagnosed Acute Myeloid Leukemia (AML) | AML Arising From Myelodysplastic Syndrome (MDS)Spain, United States, France, Korea, Republic of, Taiwan, Australia, Canada, Germany, China, Italy, Austria, Czechia, Poland, Japan, United Kingdom, Russian Federation, Netherlands, Brazil, Israel, Mexico
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Assistance Publique - Hôpitaux de ParisBristol-Myers SquibbCompletedBrain Cancer | High Grade GliomaFrance
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Turning Point Therapeutics, Inc.TerminatedAdvanced Solid Tumor | Metastatic Solid Tumor | KRAS Mutation-Related TumorsUnited States
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Memorial Sloan Kettering Cancer CenterGlaxoSmithKlineCompletedLung Cancer | Lung Cancer Metastatic | Lung Adenocarcinoma | Lung Cancer Stage IV | Recurrent Lung Adenocarcinoma | Recurrent Lung CancerUnited States
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AmgenActive, not recruitingKRAS p, G12c Mutated /Advanced Metastatic NSCLCFinland, United States, Canada, Belgium, Spain, Korea, Republic of, Netherlands, United Kingdom, Australia, Denmark, Hungary, Sweden, Taiwan, Greece, Russian Federation, Switzerland, France, Italy, Japan, Poland, Brazil, Germany, Po...
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Massachusetts General HospitalNational Cancer Institute (NCI)Active, not recruitingLow Grade Glioma | WHO Grade 3 Glioma With IDH1 Mutation | WHO Grade 3 Glioma With 1p/19q CodeletionUnited States
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HutchmedActive, not recruitingIsocitrate Dehydrogenase Gene MutationUnited States, Spain
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Shanghai Fosun Pharmaceutical Industrial Development...Suspended
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Institut de Recherches Internationales ServierActive, not recruiting
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Joaquina BarandaActive, not recruitingAcute Myeloid Leukemia | Myelodysplastic Syndromes | Cancer | Solid Tumor | Malignant Disease | Relapsed Hematologic MalignancyUnited States
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National Cancer Institute (NCI)Active, not recruitingRecurrent Lung Non-Small Cell Carcinoma | Stage IV Lung Non-Small Cell Cancer AJCC v7United States
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Dana-Farber Cancer InstituteCompletedSolid Tumors | KRAS Mutant Non-Small Cell Lung CancerUnited States
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Dana-Farber Cancer InstituteAstraZeneca; Cyclacel Pharmaceuticals, Inc.Active, not recruiting
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Dana-Farber Cancer InstitutePfizer; Array BioPharmaActive, not recruiting
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ServierActive, not recruitingCholangiocarcinoma Non-resectable | Cholangiocarcinoma MetastaticJapan
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Daiichi SankyoDaiichi Sankyo, Inc.Active, not recruiting
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PMV Pharmaceuticals, IncActive, not recruitingHealthy VolunteersUnited States
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Aprea TherapeuticsCompletedMDSUnited States, France
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Aprea TherapeuticsCompletedPlatinum Sensitive Recurrent High-grade Serous Ovarian Cancer With Mutated p53United States, France, Spain, Netherlands, United Kingdom, Belgium, Germany, Sweden
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Institut de Recherches Internationales ServierActive, not recruiting
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Sabine Mueller, MD, PhDBristol-Myers Squibb; Pacific Pediatric Neuro-Oncology Consortium; The V Foundation...CompletedGlioma | Diffuse Intrinsic Pontine Glioma | Diffuse Midline Glioma, H3 K27M-MutantUnited States, Switzerland
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Incyte CorporationActive, not recruitingCervical Cancer | Nasopharyngeal Carcinoma | Advanced Solid Tumors | Mesothelioma | Small-cell Lung Cancer | Esophageal Squamous Cell Carcinoma | Merkel Cell Carcinoma | Sarcomatoid Renal Cell Carcinoma | Anal Carcinoma | Cutaneous Squamous Cell Carcinoma | MSI-H/dMMR Tumors | PD-L1 Amplified Tumor (9p24.1) | Urothelial... and other conditionsFinland, United States, United Kingdom, Belgium, Sweden, Denmark, Norway
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Memorial Sloan Kettering Cancer CenterActive, not recruiting
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Institut de Recherches Internationales ServierCompletedGlioma | Cholangiocarcinoma | Chondrosarcoma | Other Advanced Solid TumorsUnited States, France
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M.D. Anderson Cancer CenterNational Cancer Institute (NCI)Active, not recruitingAdvanced CancersUnited States
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CelgeneAgios Pharmaceuticals, Inc.CompletedHematologic NeoplasmsUnited States, France
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University of MelbourneMerck Sharp & Dohme LLC; The AlfredTerminated
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Sidney Kimmel Comprehensive Cancer Center at Johns...National Cancer Institute (NCI); BeiGeneCompletedRecurrent Glioblastoma | Recurrent WHO Grade III Glioma | Recurrent WHO Grade II Glioma | IDH1 Mutation | IDH2 MutationUnited States
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Novartis PharmaceuticalsActive, not recruitingEGFR-mutant Non-small Cell Lung CancerTaiwan, Germany, Canada, Italy, Singapore, Hong Kong
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Memorial Sloan Kettering Cancer CenterActive, not recruitingMetastatic Non-small Cell Lung CancerUnited States
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Pierre Fabre MedicamentPfizer; Merck KGaA, Darmstadt, Germany; Ono Pharmaceutical Co. LtdCompletedBRAF V600E-mutant Metastatic Colorectal CancerFrance, Italy, United States, Spain, United Kingdom, Belgium, Austria, Japan, Netherlands
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National Cancer Institute (NCI)CompletedGlioblastoma | Gliosarcoma | Anaplastic Oligoastrocytoma | Anaplastic Astrocytoma | Diffuse Intrinsic Pontine Glioma | Diffuse Midline Glioma, H3 K27M-MutantUnited States, Canada
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PfizerCompletedBRAF or NRAS Mutant Metastatic MelanomaUnited States, Netherlands, Italy, Germany, Switzerland
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University Health Network, TorontoAbbVie; CelgeneTerminatedAcute Myeloid Leukemia | Relapsed Cancer | Refractory Cancer | IDH2 Gene MutationCanada
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University of California, San FranciscoAstraZenecaActive, not recruitingStage IIIA Non-Small Cell Lung Cancer | Stage I Non-Small Cell Lung Cancer | Stage IA Non-Small Cell Lung Cancer | Stage IB Non-Small Cell Lung Cancer | Stage II Non-Small Cell Lung Cancer | Stage IIA Non-Small Cell Lung Cancer | Stage IIB Non-Small Cell Lung CancerUnited States
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University of California, San FranciscoGenentech, Inc.Active, not recruitingPediatric Recurrent/Refractory BRAFV600E-mutant GliomasUnited States, Canada
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M.D. Anderson Cancer CenterNational Cancer Institute (NCI)Active, not recruitingBRCA1 Gene Mutation | BRCA2 Gene Mutation | Primary Peritoneal High Grade Serous Adenocarcinoma | Stage III Fallopian Tube Cancer AJCC v8 | Stage III Ovarian Cancer AJCC v8 | Stage III Primary Peritoneal Cancer AJCC v8 | Stage IIIA Fallopian Tube Cancer AJCC v8 | Stage IIIA Ovarian Cancer AJCC v8 | Stage... and other conditionsUnited States
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Dana-Farber Cancer InstituteNational Comprehensive Cancer NetworkActive, not recruitingNon-small Cell Lung CancerUnited States
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Academic and Community Cancer Research UnitedNational Cancer Institute (NCI)Active, not recruitingMetastatic Colorectal Carcinoma | Stage IV Colorectal Cancer AJCC v8 | Stage IVA Colorectal Cancer AJCC v8 | Stage IVB Colorectal Cancer AJCC v8 | Stage IVC Colorectal Cancer AJCC v8 | Unresectable CarcinomaUnited States
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Heinrich-Heine University, DuesseldorfCelgene Corporation; Koordinierungszentrum für Klinische Studien DüsseldorfActive, not recruitingMyelodysplastic Syndromes | Leukemia, Myeloid, Acute | Chronic Myelomonocytic Leukemia | IDH2 Gene Mutation | IDH2 R172 | IDH2 R140Germany
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Taiho Oncology, Inc.Institut de Recherches Internationales ServierCompletedRefractory Metastatic Colorectal CancerUnited States, Poland, France, Germany, Hungary, Italy, Russian Federation, Ukraine, Austria, Belgium, Brazil, Denmark, Puerto Rico, Spain
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Duke UniversityTerminatedNon Small Cell Lung CancerUnited States
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Eli Lilly and CompanyLoxo Oncology, Inc.CompletedHealthyUnited States
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Eli Lilly and CompanyLoxo Oncology, Inc.Completed
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Regina Elena Cancer InstituteUniversity of Roma La Sapienza; Fondazione I.R.C.C.S. Istituto Neurologico... and other collaboratorsActive, not recruiting
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Institut CurieRain Oncology IncTerminatedAdvanced or Metastatic Breast CancerFrance
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PfizerMerck KGaA, Darmstadt, Germany; Ono Pharmaceutical Co. Ltd; Pierre Fabre MedicamentCompletedBRAF V600E-mutant Metastatic Colorectal CancerUnited States, Spain, Korea, Republic of, United Kingdom, Australia, Czechia, Taiwan, Belgium, France, Hungary, Canada, Japan, Russian Federation, Netherlands, Israel, Germany, Turkey, Austria, Brazil, Poland, Italy, Argentina, Chile, Denmar... and more
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Memorial Sloan Kettering Cancer CenterJanssen Scientific Affairs, LLCActive, not recruitingMetastatic Non Small Cell Lung Cancer | Recurrent Non Small Cell Lung CancerUnited States
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John MascarenhasNational Cancer Institute (NCI); National Institutes of Health (NIH); Celgene... and other collaboratorsCompletedIDH2 Mutation | Accelerated/Blast-phase Myeloproliferative Neoplasm | Chronic-phase MyelofibrosisUnited States, Canada