Search clinical trials for: Letrozole

Total 701 results

Bristol-Myers Squibb
Mayo Clinic

Terminated

Study of BMS-754807 Combined With Letrozole or BMS-754807 Alone in Patients With Hormone Receptor-Positive Breast Cancer and Resistance to Non-Steroidal Aromatase Inhibitors

Breast Cancer

United States
Asan Medical Center

Completed

Study of GnRH-A [Leuprorelin(Lorelin Depot] Plus Leterozole +/- Everolimus for Premenopausal Women With Metastatic Breast Cancer (LEO)

Metastatic Breast Cancer

Korea, Republic of
Ahon Pharmaceutical Co., Ltd.
Zhejiang Cancer Hospital; Fudan University; Sir Run Run Shaw Hospital

Unknown

Safety, Tolerability, Pharmacokinetics and Antitumor Activity of FCN-437c

Breast Neoplasms

China
Louisiana State University Health Sciences Center...

Terminated

Repeated Bone Marrow Transplantation in Treating Women With Advanced Breast Cancer

Breast Cancer

United States
Hope Rugo, MD
GlaxoSmithKline

Completed

Reversing Hormone Resistance in Advanced Breast Cancer With Pazopanib

Breast Cancer | Breast Neoplasm

United States
Fondazione Policlinico Universitario Agostino Gemelli...

Unknown

Efficacy of Letrozole in Recurrent Ovarian Cancer (MITO32)

Epithelial Ovarian Cancer
Novartis Pharmaceuticals

Terminated

A Companion Sample Collection Protocol to Support the Discovery of Breast Cancer Aberrations With Treatment of CDK4/6 Therapy/LEE011/Ribociclib

Breast Cancer

United States
National Taiwan University Hospital

Unknown

Does Letrozole Improve Pregnancy Outcome in Fresh Embryo Transfer IVF/ICSI Cycle? (IVF/ICSI)

Reproductive Techniques, Assisted | Investigative Techniques | Reproductive Techniques

Taiwan
Mansoura University

Unknown

Endometrial Preparation by Short Course of Letrozole Before Hysteroscopic Removal of Endocavitary Lesions

Myoma;Uterus

Egypt
Shanghai Jiao Tong University School of Medicine

Completed

Traditional Chinese Medicine as Preventive Method for Osteoporosis Induced by Adjuvant Endocrine Therapy (COAT)

Breast Cancer | Osteoporosis

China
NCIC Clinical Trials Group

Completed

Letrozole in Treating Women With Recurrent or Metastatic Endometrial Cancer

Endometrial Cancer
NCIC Clinical Trials Group

Completed

Letrozole in Preventing Breast Cancer in Postmenopausal Women Who Are at Increased Risk for Breast Cancer Due to High Breast Density

Breast Cancer

United States, Canada
Cairo University

Unknown

BMI Effect on the Response to Ovulation Induction in Letrozole vs Clomid

Subfertility
Assiut University

Unknown

The Aromatase Inhibitor and Gnrh Antagonist Versus Methotrexate for Management of Undisturbed Ectopic Pregnancy

Ectopic Pregnancy
Gary Schwartz

Withdrawn

Neoadjuvant Run-In Study With TAK-228 Followed by Letrozole/TAK-228 in Women With High-Risk ER+/HER2- Breast Cancer

Breast Cancer

United States
ETOP IBCSG Partners Foundation
Breast International Group

Completed

Letrozole in Preventing Cancer in Postmenopausal Women Who Have Received 4-6 Years of Hormone Therapy for Hormone Receptor-Positive, Lymph Node-Positive, Early-Stage Breast Cancer (SOLE)

Breast Cancer

France, Spain, Switzerland, Australia, Belgium, Austria, Peru, Germany, Italy, Japan, New Zealand, Sweden, Denmark, India, United States, Chile, Russian Federation, United Kingdom, Hungary, South Africa
Postgraduate Institute of Medical Education and...

Unknown

Impact of Obesity on the Efficacy of Endocrine Therapy With Aromatase Inhibitors

Breast Cancer

India
Institute of Cancer Research, United Kingdom

Active, not recruiting

Trial of Perioperative Endocrine Therapy - Individualising Care (POETIC)

Breast Cancer

United Kingdom
SCRI Development Innovations, LLC
Novartis

Completed

Everolimus Combined With Anti-estrogen Therapy in Hormone-Receptor-Positive HER-2 Negative Advanced Breast Cancer

Breast Cancer

United States
Cairo University

Unknown

Extended Letrozole Regimen Co-treatment With Gonadotropin Releasing Hormone Antagonist Protocol Versus Gonadotropin Releasing Hormone Antagonist Protocol in Poor Responders Undergoing IVF-ET

Infertility

Egypt
Alliance for Clinical Trials in Oncology
National Cancer Institute (NCI); Cancer and Leukemia Group B

Completed

Exemestane, Letrozole, or Anastrozole in Treating Postmenopausal Women Who Are Undergoing Surgery for Stage II or Stage III Breast Cancer

Breast Cancer

United States
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Sun Yat-sen University; First People's Hospital of Foshan

Completed

Association of Survival With Maintenance Therapy in Patients With Metastatic Breast Cancer After First-line Chemotherapy

Metastatic Breast Cancer

China
Gruppo Italiano Mammella (GIM)

Unknown

Study of Anastrozole, Letrozole, or Exemestane With or Without Tamoxifen in Treating Postmenopausal Women With Hormone-Responsive Breast Cancer That Has Been Completely Removed By Surgery

Breast Cancer

Italy
Greater Baltimore Medical Center

Completed

Treatment Plan for an Individual Patient With Recurrent Uterine Papillary Serous Carcinoma (UPSC) With PIK3CA Gene Mutation

Uterine Cancer

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Completed

Letrozole and Imatinib Mesylate in Treating Postmenopausal Participants With Estrogen or Progesterone Positive Metastatic Breast Cancer

Anatomic Stage IV Breast Cancer AJCC v8 | Prognostic Stage IV Breast Cancer AJCC v8 | Estrogen Receptor Positive | Progesterone Receptor Positive | Postmenopausal | KIT Positive | PDGFR Positive

United States
University of Washington
National Cancer Institute (NCI)

Completed

Vorinostat in Treating Patients With Stage IV Breast Cancer Receiving Hormone Therapy

Male Breast Cancer | Stage IV Breast Cancer | Recurrent Breast Cancer

United States
Cairo University

Unknown

Letrozole Pretreatment With Misoprostol Versus Misoprostol Alone in Missed Abortion

Missed Abortion
Cairo University

Unknown

Letrozole Pretreatment With Misoprostol Induction of Abortion In First-Trimester Missed Miscarriage

Missed Abortion
Translational Research in Oncology
Boehringer Ingelheim

Terminated

Clinical Study for the Treatment of Breast Cancer: the Patient Will Receive Afatinib Plus Letrozole or Letrozole Alone

Breast Neoplasms

United States, Spain, Bosnia and Herzegovina, Romania
Mansoura University
Zagazig University

Unknown

The Outcomes of ICSI Cycles With and Without Letrozole

EMBRYO IMPLANTATION

Egypt
Cairo University

Unknown

Effectiveness of Pretreatment Letrozole Versus Misoprostol Alone in Missed Abortion

Medical; Abortion, Fetus
University of California, San Francisco

Completed

Pilot of Letrozole for Uterine Myomas (PLUM)

Leiomyoma | Uterine Fibroids

United States
Pfizer

Completed

Study Of Letrozole With Or Without Palbociclib (PD-0332991) For The First-Line Treatment Of Hormone-Receptor Positive Advanced Breast Cancer

Breast Cancer

Korea, Republic of, United States, Spain, Germany, Ireland, Hungary, Canada, France, Italy, Russian Federation, South Africa, Ukraine
University of Alabama at Birmingham
Genentech, Inc.

Completed

Study of Avastin (Bevacizumab) to Reverse Acquired Estrogen Independence in Previously Hormone Responsive Metastatic Breast Ca.

Metastatic Breast Cancer

United States
AstraZeneca

Completed

To Assess Safety and Effect of Olaparib on the Pharmacokinetics of Anastrozole, Letrozole & Tamoxifen, and Their Effect on Olaparib, in Patients With Advanced Solid Cancer

Solid Tumours

Belgium, Denmark, France, United Kingdom, Netherlands
Rachel Mejia

Completed

Combined Letrozole and Clomid in Women With Infertility and PCOS

Polycystic Ovary Syndrome | Infertility

United States
Jinming Yu
Jiangsu HengRui Medicine Co., Ltd.

Unknown

A Phase Ⅱ Trial of Pyrotinib Combination With CDK4/6 Inhibitor SHR6390 in Patients Prior Trastuzumab-treated Advanced HER2-Positive Breast Cancer (INPHASE)

Metastatic Breast Cancer | HER2-positive Breast Cancer

China
Mayo Clinic
National Cancer Institute (NCI)

Completed

Zoledronate in Treating Osteopenia or Osteoporosis in Postmenopausal Women Receiving Letrozole for Stage I, Stage II, or Stage IIIA Primary Breast Cancer

Breast Cancer | Osteoporosis

United States
University of Washington
National Cancer Institute (NCI)

Completed

Vorinostat in Treating Patients With Stage IV Breast Cancer Receiving Aromatase Inhibitor Therapy

Male Breast Cancer | Stage IV Breast Cancer | Recurrent Breast Cancer

United States
Loyola University
Merck Sharp & Dohme LLC

Completed

Study Of MK-0752 In Combination With Tamoxifen Or Letrozole to Treat Early Stage Breast Cancer (MK-0752)

Breast Cancer

United States
Instituto Nacional de Cancer, Brazil
Cancer Research UK Cambridge Institute

Unknown

A Study Evaluating Megestrol Acetate Modulation in Hormone Receptor Positive Advanced Breast Cancer (MEGA)

Breast Neoplasm

Brazil
Centro Nacional de Investigaciones Oncologicas...
Dr. Miguel Angel Quintela Fandiño (CNIO); Dr, Ramón Colomer i Bosch; FUNDACIÓN...

Completed

Nintedanib+Letrozole in Postmenopausal Women With Breast Cancer: Clinical Trial Safety and Pharmacodynamics

Breast Cancer

Spain
Sven O. Skouby
Zealand University Hospital; Rigshospitalet, Denmark; Hvidovre University Hospital and other collaborators

Completed

Effect of Addition of Aromatase Inhibitor to Ovarian Stimulation Therapy in IVF Treatment (RIOT-A)

Infertility

Denmark
Dana-Farber Cancer Institute
National Cancer Institute (NCI); National Institute of Allergy and Infectious...

Completed

Laboratory-Treated Lymphocyte Infusion After Haploidentical Donor Stem Cell Transplant

Myelodysplastic Syndromes | Leukemia

United States
Dharmais National Cancer Center Hospital

Completed

Neoadjuvant Hormonal Therapy Compared to Neoadjuvant Chemotherapy in Stage IIIB/C and IV Breast Cancer Patients

Breast Cancer

Indonesia
ETOP IBCSG Partners Foundation

Completed

TRial on the Endocrine Activity of Neoadjuvant Degarelix (TREND)

Breast Cancer Invasive Nos

Italy
Swiss Group for Clinical Cancer Research

Completed

Trastuzumab and Letrozole in Treating Postmenopausal Women With Progressive Advanced Breast Cancer

Breast Cancer

Switzerland
Cancer Institute and Hospital, Chinese Academy...

Unknown

Effects of Adjuvant Endocrine Therapy With Aromatase Inhibitors on the Postoperative Lipid Levels in Postmenopausal Breast Cancer Patients

Breast Cancer

China
Danish Breast Cancer Cooperative Group
Novartis; Danish Cancer Society; The Danish Medical Research Council

Terminated

Trial of Endocrine Against Locoregional Therapy First in Postmenopausal Women With Early Breast Cancer (REAL)

Operable Breast Neoplasms

Denmark
Xijing Hospital

Unknown

Breast Cancer Treatment Based on Organ-like Culture

Breast Cancer Organoids

China

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