Search clinical trials for: Phase 1b

Total 18982 results

AstraZeneca

Not yet recruiting

Volrustomig Priming Regimens Exploratory Phase II Platform Study (eVOLVE-01)

Non-small Cell Lung Cancer
M.D. Anderson Cancer Center
Regeneron Pharmaceuticals

Not yet recruiting

Phase II Trial of Ubamatamab Alone or in Combination With Cemiplimab in MUC16-Expressing SMARCB1-Deficient Malignancies

SMARCB1-Deficient Malignancies

United States
Celldex Therapeutics

Not yet recruiting

A Phase 3 Study of Barzolvolimab in Participants With Chronic Spontaneous Urticaria (EMBARQ-CSU1)

Chronic Spontaneous Urticaria
Washington University School of Medicine

Not yet recruiting

Propranolol for the Treatment of Kaposi Sarcoma in Adults

Kaposi Sarcoma

United States
M.D. Anderson Cancer Center
Qurient Co., Ltd.

Not yet recruiting

Phase I Study of Q702 With Azacitidine and Venetoclax for Relapsed or Refractory Acute Myeloid Leukemia

Acute Myeloid Leukemia

United States
Qilu Pharmaceutical (Hainan) Co., Ltd.

Recruiting

Phase 3 Study of QLG2198 in Haemodialysis Chinese Adult Subjects With Moderate-to-Severe Pruritus

Uremic Pruritus

China
University of Texas Southwestern Medical Center

Not yet recruiting

Precision Medicine in Action: Phase II Trial of Response Adaptive Ablative Pre-operative SPBI (RAPS) and Non-operative Sentinel Lymph Node Biopsy in Patients With Early-stage ER+ Breast Cancer: RAPS Trial

Breast Cancer

United States
Lei Liu

Not yet recruiting

A Phase II Study of Neoadjuvant Immunotherapy in Combination With Chemotherapy in Locally Advanced Head and Neck Squamous Cell Carcinoma

Head and Neck Squamous Cell Carcinoma
National Institute of Allergy and Infectious Diseases...
KBio Inc

Not yet recruiting

Phase 1, Randomized, Double-Blind, Placebo-controlled Study to Evaluate the Safety and Tolerability of an Enterovirus D68-specific Monoclonal Antibody in Healthy Adults

Enterovirus Infection

United States
National Institute of Allergy and Infectious Diseases...

Not yet recruiting

Safety and Immunogenicity Trial of MPV/S-2P SARS-CoV-2 Vaccine in Adults

COVID-19

United States
Assiut University

Not yet recruiting

Vitamin B12 Status and Its Impact on Chronic Haemodialysis Patient (Haemodialysis)

Vitamin B 12 Deficiency | End Stage Renal Disease on Dialysis
University Hospital, Brest

Not yet recruiting

Impact of Respiratory Rehabilitation on Quality of Life in Patients With Metastatic Non-small Cell Lung Cancer Treated With Immunotherapy and Chemotherapy in the Maintenance Phase (REHABIM)

Cancer
Resolve Therapeutics

Not yet recruiting

A Phase 2 Study of RSLV-132 in Females With Primary Sjögren's Syndrome

Primary Sjögren Syndrome
ITM Solucin GmbH

Not yet recruiting

Phase I Trial to Determine the Dose and Evaluate the PK of Lutetium Lu 177 Edotreotide Therapy in Pediatric Participants With SSTR-positive Tumors (KinLET)

Lymphoma | CNS Tumor | Solid Tumor, Childhood | Somatostatin Receptor Positive | NET
Australasian Gastro-Intestinal Trials Group
AstraZeneca; Wayne Elphinstone Research Fund

Not yet recruiting

Phase II Study of the Combination of Durvalumab (MEDI4736) (PDL1 Inhibitor) and Olaparib (PARP Inhibitor) in Advanced Cholangiocarcinoma After Initial Chemotherapy and Durvalumab (BIL-PPP)

Cholangiocarcinoma

Australia
Shanghai Hengrui Pharmaceutical Co., Ltd.

Not yet recruiting

Phase Ib/II Study of HRS2398 in Combination With Adebrelimab in Patients With Advanced Solid Tumors

Advanced Solid Tumors

China
XIANG YANQUN

Not yet recruiting

Efficacy and Safety of TPC+Apatinib+Camrelizumab vs GP+ Camrelizumab for High-Risk Nasopharyngeal Carcinoma: A Phase 3 Trial

Nasopharyngeal Carcinoma
Arthrosi Therapeutics

Recruiting

Phase 3 Evaluation of Efficacy and Safety of AR882 in Gout Patients

Hyperuricemia | Gout | Arthritis, Gouty | Gout Chronic

United States, Australia, New Zealand
Nanexa AB
Profil Institut für Stoffwechselforschung GmbH

Not yet recruiting

Phase 1 Study Assessing the Pharmacokinetics of NEX-22A in Subjects With T2D

Type 2 Diabetes
Hospices Civils de Lyon

Not yet recruiting

Study of the Quality of Life in School Aged-children With Posterior Urethral Valves (QUALIVUP)

Quality of Life | Renal Insufficiency | Urinary Incontinence | End Stage Renal Disease | Chronic Renal Disease | Bladder Dysfunction | Posterior Urethral Valve

France
Virginia Commonwealth University

Not yet recruiting

CBT-I in Primary Brain Tumor Patients: Phase IIc Randomized Feasibility Pilot Trial (CBT-I in PBT)

Glioblastoma | Astrocytoma | Oligodendroglioma | Meningioma | Primary Brain Tumor | Primary Central Nervous System (CNS) Lymphoma

United States
M.D. Anderson Cancer Center
Incyte Corporation

Not yet recruiting

Phase II Trial of Pemigatinib in Combination With Atezolizumab and Bevacizumab for Treatment of Advanced Cholangiocarcinoma With FGFR2 Fusion

Advanced Cholangiocarcinoma | FGFR2 Fusion

United States
Dana-Farber Cancer Institute
Johns Hopkins University; Translational Breast Cancer Research Consortium

Not yet recruiting

The SAPPHO Study: A Single-Arm, Phase II Study of Sequential Therapy With Curative Intent in de Novo HER2+ Metastatic Breast Cancer

Breast Cancer | HER2-positive Breast Cancer | Stage IV Breast Cancer | Breast Cancer Female | Breast Cancer Metastatic | Estrogen Receptor-positive Breast Cancer

United States
Zhejiang Cancer Hospital

Not yet recruiting

Phase II Study of Liposomal Irinotecan for Advanced Refractory Gastric Cancer

Gastric Cancer

China
Qin Ning

Recruiting

Study on Prognosis of Acute-on-chronic Liver Failure Complicated by Bacterial or Fungal Infection

Acute-On-Chronic Liver Failure

China
Rallybio IPA, LLC

Not yet recruiting

Phase 2 Study on the Pharmacokinetics and Safety of RLYB212 in Pregnant Women at Higher Risk for HPA-1a Alloimmunization

Fetal and Neonatal Alloimmune Thrombocytopenia
AstraZeneca

Not yet recruiting

A Randomised, Double-blind, Parallel Group, Placebo Controlled, 4-Week, Phase II Study to Evaluate the Effect of AZD4604 on Airway Inflammation and Biomarkers in Adults With Asthma (ARTEMISIA)

Asthma

Canada, Denmark, Germany, Spain, United Kingdom
Jazz Pharmaceuticals

Not yet recruiting

A Phase 3, Randomized, Open-label, Controlled Study Comparing the Efficacy and Safety of Zanidatamab to Trastuzumab, Each in Combination With Physician's Choice Chemotherapy, for the Treatment of Participants With Metastatic HER2-positive Breast Cancer

Metastatic HER2-positive Breast Cancer
M.D. Anderson Cancer Center

Not yet recruiting

Phase I/II Study of AD-PluReceptor Plus Tafasitamab-cxix and Lymphodepleting Chemotherapy in Patients With Autoimmune Disorders

Systemic Sclerosis | Autoimmune Disorders

United States
Chengdu Baiyu Pharmaceutical Co., Ltd.

Recruiting

A Phase l Study of By101921, an Oral PARP7 Inhibitor, in Patients With Advanced Solid Tumors

Solid Tumor, Adult

China
Yi Han
Qianfoshan Hospital

Recruiting

Prospective Observational Association Between SLCO1B1 Gene Polymorphism and the Anti-factor Xa Activity of Edoxaban in Patients With Moderate to Severe Renal Insufficiency

Renal Insufficiency | Gene Polymorphism | Edoxaban

China
Ascendis Pharma Growth Disorders A/S

Not yet recruiting

A Phase 2 Clinical Trial to Evaluate Efficacy, Safety, and Tolerability of Navepegritide in Combination With Lonapegsomatropin in Children With Achondroplasia (COACH)

Achondroplasia

Denmark, Ireland, United Kingdom
AstraZeneca

Not yet recruiting

A PROSPECTIVE, MULTI-CENTER, PHASE 4 STUDY TO ASSESS THE SAFETY OF TRASTUZUMAB DERUXTECAN, AN ANTI-HER2-ANTIBODY DRUG CONJUGATE IN INDIAN PATIENTS WITH UNRESECTABLE OR METASTATIC HER2-POSITIVE BREAST CANCER WHO HAVE RECEIVED A PRIOR ANTI-HER2-BASED REGIMEN (STRIDE)

BREAST CANCER
Sun Yat-sen University
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.

Recruiting

First-line Anlotinib Combined With Penpulimab for Advanced Pheochromocytoma: A Single-arm, Multicenter, Prospective Phase II Study

Pheochromocytoma

China
Ensemble Hospitalier de la Côte

Not yet recruiting

Blood Flow Restriction in Post-surgery Rehabilitation of Latarjet Procedure (BFR)

Shoulder Dislocation
Novartis Pharmaceuticals

Not yet recruiting

Clinical Study of Asciminib in Previously Treated Indian Patients With Ph+ CML-CP Without T315I Mutation and in Patients With Ph+ CML-CP With T315I Mutation (ASC4INDIA)

Philadelphia Chromosome-Positive Chronic Myeloid Leukemia in Chronic Phase
BeiGene

Not yet recruiting

A Phase 1 Study of BGB-B2033, Alone or in Combination With Tislelizumab, in Participants With Advanced or Metastatic Solid Tumors

Metastatic Solid Tumor | Advanced Hepatocellular Carcinoma | Metastatic Hepatocellular Carcinoma | Alpha-fetoprotein (AFP)-Producing Gastric Cancer | Extragonadal Yolk Sac Tumors | Glypican-3 (GPC3)-Positive Squamous Non-small Cell Lung Cancer
Bayer

Not yet recruiting

A Study to Learn About the Safety of BAY3283142 in People With Mild to Moderate High Blood Pressure

Chronic Kidney Disease | Arterial Hypertension | Non-proliferative Diabetic Retinopathy

Germany
Sheba Medical Center

Recruiting

Health Coaching Telemedicine Program for Lung Transplant Candidates With End-stage Lung Disease. (HCTP)

Copd | End Stage Lung Disease

Israel
Peking University Third Hospital
Jilin Provincial Tumor Hospital; Affiliated Hospital of Hebei University; Hebei...

Not yet recruiting

Nab-Paclitaxel Plus Cisplatin With Concurrent Radiotherapy for Patients With Locally Advanced Cervical Cancer: A Multicentre, Single-arm, Phase II Trial.

Cervical Cancer
Institute of Hematology & Blood Diseases Hospital...

Not yet recruiting

Phase II Study of Post-Transplant Low-Dose Inotuzumab Ozogamicin to Prevent Relapse of Acute Lymphoblastic Leukemia

Acute Lymphoid Leukemia

China
Henan Cancer Hospital

Not yet recruiting

This is a Phase II, Open-label, Multicentre Study of Zanubrutinib-containing Regimens in Patients With Newly Diagnosed Mantle Cell Lymphoma

Lymphoma, Non-Hodgkin | Lymphoma, Mantle-Cell
Aldeyra Therapeutics, Inc.

Recruiting

A Clinical Trial to Assess the Safety and Efficacy of Subjects With Dry Eye Disease

Dry Eye Disease

United States
Ascentage Pharma Group Inc.

Not yet recruiting

A Phase 3 Registrational Study of Olverembatinib (HQP1351) in Patients With CML (POLARIS-2)

Chronic Myeloid Leukemia | CML | CML, Chronic Phase

United States
Endeavor Biomedicines, Inc.

Not yet recruiting

A Phase 2 Trial of ENV-101 in Patients With Lung Fibrosis (WHISTLE-PF Trial)

Idiopathic Pulmonary Fibrosis | Progressive Fibrosing Interstitial Lung Disease | Progressive Pulmonary Fibrosis

United States, Switzerland, Canada, Australia, Austria, United Kingdom, Malaysia, Mexico, Germany, Ireland, Korea, Republic of
Medical University of South Carolina

Not yet recruiting

Phase 2 Study of Fingolimod in Lung Cancers

Non Small Cell Lung Cancer | Small-cell Lung Cancer
BeiGene

Not yet recruiting

Phase 1 First-in-Human Study of BGB-C354 Alone and in Combination With Tislelizumab in Participants With Advanced Solid Tumors

Advanced Solid Tumor
Merit Medical Systems, Inc.

Not yet recruiting

Observational Study of the Merit HeRO® Graft and Super HeRO® in Patients on Hemodialysis (PReSeRVE-HD)

End Stage Renal Disease | Hemodialysis Access Failure
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University

Recruiting

A Single-arm Phase II Clinical Study of the Efficacy and Safety of Camrelizumab Combined With GEMOX for Unresectable GBCs

Unresectable Gallbladder Cancer

China
Jinghui Wang

Recruiting

A Prospective, Single-arm, Phase II Clinical Trial to Evaluate the Efficacy and Safety of Tafolecimab and Sintilimab Combined With Chemotherapy in Patients With Advanced or Metastatic Driver Gene-negative Non-small Cell Lung Cancer After Failure of First-line Immunotherapy.

Lung Cancer

China

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