Search clinical trials for: malignant brain tumor

Total 67852 results

Sidney Kimmel Comprehensive Cancer Center at Johns...

Terminated

Phase I Study of Orally Administered Aminolevulinic Acid for Resection of Malignant Astrocytomas

Glioma | Astrocytoma

United States
Alliance for Clinical Trials in Oncology
National Cancer Institute (NCI)

Terminated

Temozolomide and Radiation Therapy in Treating Patients With Stage IV Malignant Melanoma With Measurable and Unresectable Cancer of the Central Nervous System

Metastatic Cancer | Melanoma (Skin)

United States
PersonGen BioTherapeutics (Suzhou) Co., Ltd.
The First People's Hospital of Hefei; Hefei Binhu Hospital

Unknown

CAR-T Cell Immunotherapy in MUC1 Positive Solid Tumor

Malignant Glioma of Brain | Gastric Carcinoma | Colorectal Carcinoma

China
PersonGen BioTherapeutics (Suzhou) Co., Ltd.
The First People's Hospital of Hefei; Hefei Binhu Hospital

Unknown

CAR-pNK Cell Immunotherapy in MUC1 Positive Relapsed or Refractory Solid Tumor

Hepatocellular Carcinoma | Malignant Glioma of Brain | Non-small Cell Lung Cancer | Gastric Carcinoma | Colorectal Carcinoma | Pancreatic Carcinoma | Triple-Negative Invasive Breast Carcinoma

China
Dana-Farber Cancer Institute
Brigham and Women's Hospital

Completed

A-protein Levels in Adult and Pediatric Brain Tumor Patients

Malignant Childhood Central Nervous System Neoplasm

United States
Central Hospital, Nancy, France

Completed

Myocet® in Children With Relapsed or Refractory Non-brainstem Malignant Glioma (MYOCET)

Malignant Glioma

France
Annick Desjardins
Tactical Therapeutics, Inc.

Terminated

Ph 1/2 CTO With Lomustine for Bevacizumab-Naive Recurrent Glioma

Malignant Glioma (WHO Grade III or IV)

United States
Hoffmann-La Roche

Completed

A Study of Vemurafenib in Metastatic Melanoma Participants With Brain Metastases

Malignant Melanoma

Spain, United States, Canada, Germany, Netherlands, France, Italy, United Kingdom, Israel, Australia
O'Dorisio, M S
National Cancer Institute (NCI)

Completed

Radiolabeled Octreotide in Treating Children With Advanced or Refractory Solid Tumors

Sarcoma | Unspecified Childhood Solid Tumor, Protocol Specific | Brain and Central Nervous System Tumors | Neuroblastoma | Pheochromocytoma | Islet Cell Tumor | Gastrointestinal Carcinoid Tumor

United States
University Children's Hospital, Zurich

Completed

Magnetic Resonance (MR) Guided Focused Ultrasound in the Treatment of Brain Tumors (FUS-Tumor)

Malignant Brain Tumors

Switzerland
Jonsson Comprehensive Cancer Center
National Cancer Institute (NCI); National Institutes of Health (NIH)

Completed

Cellular Immunotherapy Study for Brain Cancer (alloCTL)

Glioblastoma Multiforme | Anaplastic Astrocytoma | Anaplastic Oligodendroglioma | Gliomas | Anaplastic Mixed Glioma | Malignant Meningioma

United States
medac GmbH
IKP

Completed

Clinical Study on 5-aminolevulinic Acid Hydrochloride (5-ALA) for Fluorescence-guided Resection of Malignant Gliomas

Brain Neoplasm
Memorial Sloan Kettering Cancer Center
National Cancer Institute (NCI)

Completed

Paclitaxel, Ifosfamide, and Carboplatin Followed By Autologous Stem Cell Transplant in Treating Patients With Germ Cell Tumors That Did Not Respond to Cisplatin

Testicular Germ Cell Tumor | Ovarian Cancer | Brain and Central Nervous System Tumors | Teratoma | Extragonadal Germ Cell Tumor

United States
Constantinos Hadjipanayis
National Cancer Institute (NCI); NX PharmaGen

Withdrawn

More Complete Removal of Malignant Brain Tumors by Fluorescence-Guided Surgery

Glioblastoma | Brain Cancer | Brain Tumors | Brain Tumor, Recurrent | Benign Neoplasms, Brain | Brain Neoplasms, Benign | Brain Neoplasms, Malignant | Brain Tumor, Primary | Intracranial Neoplasms | Neoplasms, Brain | Neoplasms, Intracranial | Primary Brain Neoplasms | Primary Malignant Brain Neoplasms | Primary Malignant... and other conditions

United States
University Hospital, Bonn
Mundipharma Research GmbH & Co KG

Terminated

A Clinical Trial to Assess the Safety & Efficacy of the Treatment of Patients With Metastasis From Malignant Melanoma - Treatment Consists of the Substances Lomustine (Capsules) & Cytarabine (Injected Into an Area Near the Spinal Cord), Accompanied by Radiotherapy of the Brain

Leptomeningeal Metastasis From Malignant Melanoma

Germany
Amgen

Completed

AMG 595 First-in-Human in Recurrent Gliomas

Glioblastoma Multiforme | Advanced Malignant Glioma | Anaplastic Astrocytomas

United States, Australia
MultiCare Health System Research Institute

Terminated

A Study of Aminolevulinic Acid Used to Enhance Visualization and Surgical Removal of Brain Tumors

Glioma | Glioblastoma | Astrocytoma | Glioblastoma Multiforme | Malignant Glioma

United States
Memorial Sloan Kettering Cancer Center
National Cancer Institute (NCI); Weill Medical College of Cornell University; Schering-Ploug...

Completed

Temozolomide in Treating Patients With Recurrent Glioblastoma Multiforme or Other Malignant Glioma

Brain and Central Nervous System Tumors

United States
Annick Desjardins
Tactical Therapeutics, Inc.

Terminated

Phase 1/2 CTO + Bevacizumab for Recurrent Glioma Post-Bevacizumab Failure

Malignant Glioma (WHO Grade III or IV)

United States
Memorial Sloan Kettering Cancer Center
Pfizer; Dana-Farber Cancer Institute; University of Pittsburgh; University of Virginia

Completed

Phase II Trial of Sunitinib (SU011248) in Patients With Recurrent or Inoperable Meningioma

Neurofibromatosis | Meningioma | CNS Cancer | Hemangioblastoma | Intracranial Hemangiopericytoma

United States
John Sampson
National Cancer Institute (NCI)

Completed

Chemotherapy, Radiation Therapy, and Vaccine Therapy With Basiliximab in Treating Patients With Glioblastoma Multiforme That Has Been Removed by Surgery (ZAP IT)

Malignant Neoplasms of Brain

United States
National Cancer Institute (NCI)

Terminated

RO4929097and Bevacizumab in Treating Patients With Progressive or Recurrent Malignant Glioma

Adult Anaplastic Astrocytoma | Adult Anaplastic Oligodendroglioma | Adult Giant Cell Glioblastoma | Adult Glioblastoma | Adult Gliosarcoma | Recurrent Adult Brain Tumor

United States
Katy Peters
Amgen

Completed

AMG 102 and Avastin for Recurrent Malignant Glioma

Glioblastoma Multiforme | Gliosarcoma

United States
Memorial Sloan Kettering Cancer Center
National Cancer Institute (NCI)

Completed

Arsenic Trioxide in Treating Patients With Advanced Neuroblastoma or Other Childhood Solid Tumors

Sarcoma | Kidney Cancer | Ovarian Cancer | Brain and Central Nervous System Tumors | Neuroblastoma | Retinoblastoma | Liver Cancer | Extragonadal Germ Cell Tumor | Childhood Germ Cell Tumor

United States
Virginia Commonwealth University

Withdrawn

Dietary and Exercise Interventions in Preventing Cardiovascular Disease in Younger Survivors of Leukemia, Lymphoma, or Brain Tumors

Malignant Childhood Neoplasm | Childhood Hodgkin Lymphoma | Childhood Brain Tumor | Childhood Non-Hodgkin Lymphoma
National Cancer Institute (NCI)

Completed

Tamoxifen and Bortezomib to Treat Recurrent Brain Tumors

Glioma

United States
Duke University
National Cancer Institute (NCI)

Completed

Imatinib Mesylate, Vatalanib, and Hydroxyurea in Treating Patients With Recurrent or Relapsed Malignant Glioma

Brain and Central Nervous System Tumors

United States
Jonsson Comprehensive Cancer Center
National Cancer Institute (NCI)

Completed

Vaccine Therapy in Treating Patients With Malignant Glioma

Brain and Central Nervous System Tumors

United States
National Cancer Institute (NCI)

Completed

VEGF Trap in Treating Patients With Recurrent Malignant Gliomas That Did Not Respond to Temozolomide

Adult Anaplastic Astrocytoma | Adult Anaplastic Oligodendroglioma | Adult Giant Cell Glioblastoma | Adult Gliosarcoma | Recurrent Adult Brain Tumor

United States
National Cancer Institute (NCI)

Terminated

Sunitinib to Treat Recurrent Brain Cancer

Glioblastoma Multiforme | Malignant Gliomas | Anaplastic Gliomas

United States
National Cancer Institute (NCI)

Completed

RO4929097, Temozolomide, and Radiation Therapy in Treating Patients With Newly Diagnosed Malignant Glioma

Adult Anaplastic Astrocytoma | Adult Anaplastic Ependymoma | Adult Diffuse Astrocytoma | Adult Ependymoma | Adult Giant Cell Glioblastoma | Adult Glioblastoma | Adult Gliosarcoma | Adult Mixed Glioma | Adult Myxopapillary Ependymoma | Adult Oligodendroglioma | Adult Pilocytic Astrocytoma | Adult Pineal Gland... and other conditions

United States
Merck Sharp & Dohme LLC
Ariad Pharmaceuticals

Completed

Safety Study of AP23573 in Patients With Progressive or Recurrent Glioma (8669-023)(COMPLETED)

Glioblastoma | Malignant Glioma | Gliosarcoma

United States
University of South Florida
National Cancer Institute (NCI)

Terminated

Cyproheptadine in Preventing Weight Loss in Children Receiving Chemotherapy for Cancer

Cancer

United States
National Cancer Institute (NCI)

Completed

Erlotinib and Temsirolimus in Treating Patients With Recurrent Malignant Glioma

Adult Anaplastic Astrocytoma | Adult Anaplastic Oligodendroglioma | Adult Diffuse Astrocytoma | Adult Giant Cell Glioblastoma | Adult Glioblastoma | Adult Gliosarcoma | Adult Mixed Glioma | Adult Pilocytic Astrocytoma | Adult Pineal Gland Astrocytoma | Recurrent Adult Brain Tumor | Adult Subependymal Giant...

United States
City of Hope Medical Center

Completed

Phase I Study of Cellular Immunotherapy for Recurrent/Refractory Malignant Glioma Using Intratumoral Infusions of GRm13Z40-2, An Allogeneic CD8+ Cytolitic T-Cell Line Genetically Modified to Express the IL 13-Zetakine and HyTK and to be Resistant to Glucocorticoids, in Combination With Interleukin-2

Glioblastoma | Brain Tumor | Gliosarcoma | Anaplastic Astrocytoma | Anaplastic Ependymoma | Anaplastic Oligodendroglioma | Giant Cell Glioblastoma | Anaplastic Meningioma | Mixed Glioma | Brain Stem Glioma | Ependymoblastoma | Grade III Meningioma | Meningeal Hemangiopericytoma | Pineal Gland Astrocytoma

United States
Pediatric Brain Tumor Consortium
National Cancer Institute (NCI); PTC Therapeutics

Completed

PTC299 in Treating Young Patients With Refractory or Recurrent Primary Central Nervous System Tumors

Brain and Central Nervous System Tumors

United States
National Cancer Institute (NCI)

Completed

Chemotherapy Followed by Radiation Therapy in Treating Patients With Malignant Glioma

Brain and Central Nervous System Tumors

United States
National Cancer Institute (NCI)

Completed

Temozolomide and O6-benzylguanine in Treating Children With Solid Tumors

Sarcoma | Kidney Cancer | Unspecified Childhood Solid Tumor, Protocol Specific | Ovarian Cancer | Brain and Central Nervous System Tumors | Neuroblastoma | Liver Cancer | Extragonadal Germ Cell Tumor | Childhood Germ Cell Tumor

United States
Amgen

Completed

A Phase II Study to Treat Advanced Malignant Glioma

Advanced Malignant Glioma
Northwell Health

Completed

Super-Selective Intraarterial Intracranial Infusion of Avastin (Bevacizumab)

Glioblastoma Multiforme | Anaplastic Astrocytoma

United States
Hadassah Medical Organization

Completed

Palliative Re-irradiation for Progressive Diffuse Intrinsic Pontine Glioma (DIPG) in Children

Pediatric Malignant Brain Tumor -Diffuse Intrinsic Pontine Glioma

Israel
Maastricht University Medical Center

Completed

Comparison of Standard Neuronavigation With Intraoperative Magnetic Resonance Imaging (MRI) for the Neurosurgical Treatment of Malignant Brain Tumors (RACING)

Glioblastoma Multiforme

Netherlands, Belgium
Monte Verde SA
FLENI Instituto de Rehabilitación y Educación Terapéutica, BA, Argentina.; Bioanalytical... and other collaborators

Completed

Bioequivalence Study of Temozolomide in Patients With Primary Tumors of the Central Nervous System

Brain Neoplasms, Malignant, Primary

Argentina
University of Minnesota
Children's Cancer Research Fund United States

Terminated

Effects of Methylphenidate on Attention Deficits in Childhood Cancer Survivors

Lymphoblastic Lymphoma | Brain Tumors | Lymphoblastic Leukemia, Acute, Childhood | Lymphoblastic Leukemia | Leukemia, Lymphocytic, Acute | Leukemia, Lymphoblastic, Acute | Brain Neoplasms, Malignant | ALL, Childhood | Leukemia, Lymphoblastic, Acute, Philadelphia-Positive | Lymphoblastic Leukemia, Acute | Leukemia... and other conditions

United States
Darell D. Bigner, MD, PhD
National Institute of Neurological Disorders and Stroke (NINDS)

Terminated

Study of Immunotoxin, MR1-1 (MR1-1)

Supratentorial Malignant Brain Tumor

United States
Case Comprehensive Cancer Center
National Cancer Institute (NCI)

Terminated

A Computer-Based Intervention for Distance Caregivers of Parents With Advanced Cancer

Stage IV Lung Cancer | Malignant Brain Tumor

United States
BBB-Therapeutics B.V.

Completed

An Open-label, Phase I/IIa, Dose Escalating Study of 2B3-101 in Patients With Solid Tumors and Brain Metastases or Recurrent Malignant Glioma.

Melanoma | Breast Cancer | Lung Cancer | Malignant Glioma | Brain Metastases

United States, Netherlands, France, Belgium
Jeffrey N. Bruce

Unknown

Safety Study of Intracerebral Topotecan for Recurrent Brain Tumors

Brain Neoplasms, Primary Malignant

United States
INSYS Therapeutics Inc
Pediatric Brain Tumor Consortium (PBTC), St. Jude Children's Research Hospital

Withdrawn

Phase I/II Trial of Intracerebral IL13-PE38QQR Infusions in Pediatric Patients With Recurrent Malignant Glioma

Recurrent Malignant Glioma

United States
M.D. Anderson Cancer Center

Withdrawn

18-F-Fluoroacetate as PET Imaging Agent

Breast Cancer | Prostate Cancer | Brain Cancer

Search clinical trials for: malignant brain tumor

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