Search clinical trials for: unresectable or recurrent colorectal cancer

Total 249198 results

Barbara Ann Karmanos Cancer Institute
National Cancer Institute (NCI)

Completed

Bevacizumab, Oxaliplatin, and Docetaxel in Treating Patients With Locally Advanced Unresectable or Metastatic Stomach or Gastroesophageal Junction Cancer

Gastric Cancer | Esophageal Cancer

United States
Peking University Third Hospital

Completed

The Physical Dosimetry Study and Preliminary Clinical Results of 3D-printing Non Co-planar Template Assisted With CT-guidance for Iodine-125 Seed Brachytherapy in Pelvic Recurrent Rectum Carcinoma After Surgery and External Beam Radiotherapy

Rectum Cancer, Recurrent | Brachytherapy, Radioisotope
National Cancer Institute (NCI)

Completed

Vorinostat in Treating Patients With Metastatic or Unresectable Melanoma

Recurrent Melanoma | Stage IV Melanoma | Uveal Melanoma | Ciliary Body and Choroid Melanoma, Medium/Large Size | Iris Melanoma | Recurrent Intraocular Melanoma | Extraocular Extension Melanoma

Canada, United States
Sidney Kimmel Comprehensive Cancer Center at Johns...
National Cancer Institute (NCI)

Terminated

Cyclophosphamide and Cryoablation in Treating Patients With Advanced or Metastatic Epithelial Cancer

Cancer

United States
University of California, Davis
National Cancer Institute (NCI); Millennium Pharmaceuticals, Inc.

Completed

Irinotecan and Alisertib in Treating Patients With Advanced Solid Tumors or Colorectal Cancer

Unspecified Adult Solid Tumor, Protocol Specific | Mucinous Adenocarcinoma of the Rectum | Signet Ring Adenocarcinoma of the Rectum | Mucinous Adenocarcinoma of the Colon | Signet Ring Adenocarcinoma of the Colon | Stage IIIA Colon Cancer | Recurrent Colon Cancer | Recurrent Rectal Cancer

United States
Dana-Farber Cancer Institute
Genentech, Inc.; Eisai Inc.

Terminated

Phase II Study of Eribulin Mesylate, Trastuzumab, and Pertuzumab in Women With Metastatic, Unresectable Locally Advanced, or Locally Recurrent HER2-Positive Breast Cancer

Metastatic Breast Cancer | HER2-positive Breast Cancer

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Completed

Heat Therapy in Treating Patients With Unresectable Primary or Metastatic Liver Cancer

Metastatic Cancer | Liver Cancer

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI); Taiho Pharmaceutical Co., Ltd.

Completed

TAC-101 in Treating Patients With Advanced Hepatocellular Carcinoma (Liver Cancer)

Liver Cancer

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Completed

Chemotherapy Plus Hormone Therapy Versus Androgen Suppression in Treating Patients With Metastatic or Unresectable Prostate Cancer

Prostate Cancer

United States
University Health Network, Toronto
National Cancer Institute (NCI)

Completed

3-AP and Gemcitabine in Treating Patients With Recurrent, Unresectable, or Metastatic Pancreatic Cancer

Pancreatic Cancer

Canada
Montefiore Medical Center
National Cancer Institute (NCI)

Completed

Combination Chemotherapy Plus Interferon Alfa Followed by Filgrastim in Treating Patients With Gastrointestinal Tract Cancer

Gastric Cancer | Pancreatic Cancer | Small Intestine Cancer | Liver Cancer | Extrahepatic Bile Duct Cancer | Gastrointestinal Carcinoid Tumor

United States
Montefiore Medical Center
National Cancer Institute (NCI)

Completed

Irinotecan and Capecitabine in Treating Patients With Solid Tumors

Cancer

United States
Mayo Clinic
National Cancer Institute (NCI)

Terminated

TLR8 Agonist VTX-2337 and Cyclophosphamide in Treating Patients With Metastatic, Persistent, Recurrent, or Progressive Solid Tumors

Recurrent Renal Cell Carcinoma | Stage IV Skin Melanoma | Recurrent Non-Small Cell Lung Carcinoma | Stage IV Non-Small Cell Lung Cancer | Metastatic Pancreatic Adenocarcinoma | Recurrent Pancreatic Carcinoma | Stage IV Breast Cancer | Recurrent Breast Carcinoma | Recurrent Colorectal Carcinoma | Colorectal... and other conditions

United States
Merck Sharp & Dohme LLC

Completed

A Study to Determine the Activity of Robatumumab (SCH 717454, MK-7454) in Participants With Relapsed or Recurrent Colorectal Cancer (P04721, MK-7454-003)

Colorectal Cancer
Wake Forest University Health Sciences
National Cancer Institute (NCI)

Completed

Thalidomide in Treating Patients Who Have Undergone Surgery and Chemotherapy for Cancer That Has Spread Throughout the Abdomen Due to Colorectal Cancer or Appendix Cancer

Colorectal Cancer | Carcinoma of the Appendix

United States
City of Hope Medical Center
National Cancer Institute (NCI)

Terminated

FOLFIRI and Panitumumab in Treating Patients With RAS and BRAF Wild-Type Metastatic Colorectal Cancer

Recurrent Colorectal Carcinoma | Stage IVA Colorectal Cancer | Stage IVB Colorectal Cancer

United States
University Hospital, Bordeaux

Completed

Benchmarking Trial Between France and Australia Comparing Management of Primary Rectal Cancer Beyond TME (Total Mesorectum Excision) and Locally Recurrent Rectal Cancer (PELVICARE)

Rectal Cancer

Australia, France
Wake Forest University Health Sciences
National Cancer Institute (NCI)

Completed

Intraperitoneal Hyperthermic Perfusion With Oxaliplatin in Treating Patients With Stage IV Peritoneal Cancer Due to Appendix Cancer or Colorectal Cancer

Colorectal Cancer | Primary Peritoneal Cavity Cancer | Carcinoma of the Appendix

United States
Immodulon Therapeutics Ltd

Terminated

Study of IMM 101 in Combination With Standard of Care in Patients With Metastatic or Unresectable Cancer (MODULATE)

Metastatic Cancer

France, United Kingdom
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Genetic Analysis Using Blood or Bone Marrow From Participants With Neuroblastoma or Noncancerous Conditions

Recurrent Neuroblastoma | Localized Resectable Neuroblastoma | Localized Unresectable Neuroblastoma | Regional Neuroblastoma | Stage 4 Neuroblastoma

United States
National Cancer Institute (NCI)

Completed

TKM 080301 for Primary or Secondary Liver Cancer

Colorectal Cancer With Hepatic Metastases | Pancreas Cancer With Hepatic Metastase | Gastric Cancer With Hepatic Metastase | Breast Cancer With Hepatic Metastase | Ovarian Cancer With Hepatic Metastase

United States
Medical University of South Carolina

Terminated

Gemcitabine and Irinotecan in Treating Patients With Locally Advanced Unresectable or Metastatic Kidney Cancer

Kidney Cancer

United States
Centre Georges Francois Leclerc
National Cancer Institute, France; Hospira, now a wholly owned subsidiary of...

Completed

Hepatic Arterial Chemotherapy With Raltitrexed and Oxaliplatin Versus Standard Chemotherapy in Unresectable Liver Metastases From Colorectal Cancer After Conventional Chemotherapy Failure (HEARTO)

Colorectal Cancer | Liver Metastases

France
Medical University of South Carolina

Terminated

Capecitabine and Oxaliplatin in Treating Patients With Locally Advanced, Unresectable, or Metastatic Stomach Cancer

Gastric Cancer

United States
Wake Forest University Health Sciences

Completed

Quality of Life and Survivorship Care in Patients Undergoing Hyperthermic Intraperitoneal Chemotherapy (HIPEC) (HOPE)

Unspecified Childhood Solid Tumor, Protocol Specific | Pseudomyxoma Peritonei | Stage IV Ovarian Epithelial Cancer | Stage IV Ovarian Germ Cell Tumor | Ovarian Sarcoma | Recurrent Ovarian Epithelial Cancer | Stage IV Colon Cancer | Recurrent Colon Cancer | Carcinoma of the Appendix | Ovarian Stromal Cancer and other conditions

United States
Wake Forest University Health Sciences
National Cancer Institute (NCI)

Terminated

Genomic Sequencing in Determining Treatment in Patients With Metastatic Cancer or Cancer That Cannot Be Removed by Surgery

Stage IIIA Non-Small Cell Lung Cancer | Stage IIIB Non-Small Cell Lung Cancer | Recurrent Non-Small Cell Lung Carcinoma | Stage IV Non-Small Cell Lung Cancer | Unresectable Malignant Neoplasm | Metastatic Neoplasm | Recurrent Neoplasm

United States
Samsung Medical Center

Unknown

Concurrent Chemo-proton Radiotherapy With or Without Resection and Spacer Insertion for Loco-regional Recurrence of Previous Irradiated Rectal Cancer (RECCPT)

Previously Irradiated Recurrent Rectal Cancer

Korea, Republic of
Cascadian Therapeutics Inc.

Completed

Phase 1 and 2 Study of PX-866 and Cetuximab

Incurable Metastatic Colorectal Carcinoma | Incurable Progressive, Recurrent or Metastatic Squamous Cell Carcinoma of the Head and Neck

United States, Canada
Alliance for Clinical Trials in Oncology
Bristol-Myers Squibb; National Cancer Institute (NCI); Eli Lilly and Company

Terminated

FOLFIRI or FOLFOX With or Without Cetuximab in Patients With Metastatic Adenocarcinoma of the Colon or Rectum

Colorectal Cancer

United States
National Cancer Institute (NCI)

Completed

Lapatinib in Treating Patients With Locally Advanced or Metastatic Biliary Tract or Liver Cancer That Cannot Be Removed By Surgery

Advanced Adult Primary Liver Cancer | Localized Unresectable Adult Primary Liver Cancer | Recurrent Adult Primary Liver Cancer | Recurrent Extrahepatic Bile Duct Cancer | Recurrent Gallbladder Cancer | Unresectable Extrahepatic Bile Duct Cancer | Unresectable Gallbladder Cancer | Adult Primary Hepatocellular...

United States
Fox Chase Cancer Center
National Cancer Institute (NCI)

Terminated

Irinotecan-Eluting Beads in Treating Patients With Refractory Metastatic Colon or Rectal Cancer That Has Spread to the Liver

Mucinous Adenocarcinoma of the Rectum | Signet Ring Adenocarcinoma of the Rectum | Liver Metastases | Mucinous Adenocarcinoma of the Colon | Signet Ring Adenocarcinoma of the Colon | Recurrent Colon Cancer | Recurrent Rectal Cancer | Stage IVA Colon Cancer | Stage IVA Rectal Cancer | Stage IVB Colon Cancer and other conditions

United States
City of Hope Medical Center
National Cancer Institute (NCI); Array BioPharma

Completed

MEK Inhibitor MEK162 in Combination With Leucovorin Calcium, Fluorouracil, and Oxaliplatin in Treating Patients With Advanced Metastatic Colorectal Cancer

Recurrent Colon Cancer | Recurrent Rectal Cancer | Stage IVA Colon Cancer | Stage IVA Rectal Cancer | Stage IVB Colon Cancer | Stage IVB Rectal Cancer

United States
University of Washington
National Cancer Institute (NCI)

Terminated

A Trial of Maintenance ADAPT Therapy With Capecitabine and Celecoxib in Patients With Metastatic Colorectal Cancer (ADAPT)

Recurrent Colon Carcinoma | Recurrent Rectal Carcinoma | Stage IVA Colon Cancer | Stage IVA Rectal Cancer | Stage IVB Colon Cancer | Stage IVB Rectal Cancer

United States
Roswell Park Cancer Institute
National Cancer Institute (NCI); National Comprehensive Cancer Network

Completed

Pralatrexate and Oxaliplatin in Treating Patients With Unresectable or Metastatic Esophageal, Stomach, or Gastroesophageal Junction Cancer

Gastric Adenocarcinoma | Recurrent Gastric Carcinoma | Esophageal Undifferentiated Carcinoma | Gastric Squamous Cell Carcinoma | Adenocarcinoma of the Gastroesophageal Junction | Stage IV Gastric Cancer | Stage IIIB Gastric Cancer | Stage IIIC Gastric Cancer | Stage IV Esophageal Adenocarcinoma | Stage... and other conditions

United States
Alliance for Clinical Trials in Oncology
National Cancer Institute (NCI); Cancer and Leukemia Group B

Terminated

Combination Chemotherapy Plus Bevacizumab With or Without Oxaliplatin in Treating Older Patients With Metastatic Colorectal Cancer

Colorectal Cancer | Neurotoxicity | Cognitive/Functional Effects
Ohio State University Comprehensive Cancer Center

Completed

Single Incision Laparoscopic Surgery in Treating Patients With Colorectal Disease

Crohn Disease | Familial Adenomatous Polyposis | Stage IIIA Colon Cancer | Stage IIIB Colon Cancer | Stage IIIC Colon Cancer | Recurrent Colon Cancer | Stage I Colon Cancer | Stage IIA Colon Cancer | Stage IIB Colon Cancer | Stage IIC Colon Cancer | Adenomatous Polyp | Hereditary Intestinal Polyposis Syndrome

United States
Masonic Cancer Center, University of Minnesota

Completed

Bortezomib and Cetuximab in Treating Patients With Advanced Solid Tumors

Sarcoma | Kidney Cancer | Breast Cancer | Head and Neck Cancer | Colorectal Cancer | Pancreatic Cancer | Lung Cancer | Unspecified Adult Solid Tumor, Protocol Specific

United States
Masonic Cancer Center, University of Minnesota

Terminated

Oxaliplatin, Docetaxel, and Radiation Therapy in Treating Patients With Unresectable Stage II/III or Recurrent NSCLC

Lung Cancer

United States
Masonic Cancer Center, University of Minnesota

Terminated

Amifostine to Protect From Side Effects of PSCT in Treating Patients With Solid Tumors

Sarcoma | Kidney Cancer | Ovarian Cancer | Brain and Central Nervous System Tumors | Chordoma | Neuroblastoma | Retinoblastoma | Liver Cancer | Childhood Germ Cell Tumor

United States
Masonic Cancer Center, University of Minnesota

Completed

Bortezomib and Gemcitabine in Treating Older Patients With Advanced Solid Tumors

Sarcoma | Kidney Cancer | Breast Cancer | Head and Neck Cancer | Colorectal Cancer | Pancreatic Cancer | Ovarian Cancer | Lung Cancer | Prostate Cancer

United States
National Cancer Institute (NCI)

Completed

Bevacizumab and Sorafenib in Treating Patients With Unresectable Stage III or Stage IV Malignant Melanoma

Stage IV Skin Melanoma | Recurrent Melanoma | Stage III Skin Melanoma

United States
Southwest Oncology Group
National Cancer Institute (NCI)

Completed

S0330 Erlotinib in Treating Patients With Unresectable or Metastatic Malignant Peripheral Nerve Sheath Tumor

Sarcoma

United States
OHSU Knight Cancer Institute
National Cancer Institute (NCI)

Completed

Everolimus and Imatinib Mesylate in Treating Patients With Metastatic or Unresectable Kidney Cancer

Kidney Cancer

United States
National Cancer Institute (NCI)

Completed

Eribulin Mesylate as Second-Line Therapy for Locally Advanced, Unresectable, or Metastatic Pancreatic Cancer Patients

Pancreatic Cancer | Adenocarcinoma of the Pancreas | Recurrent Pancreatic Cancer | Stage III Pancreatic Cancer | Stage IV Pancreatic Cancer | Stage II Pancreatic Cancer

Canada
National Cancer Institute (NCI)

Completed

Sunitinib Malate in Treating Patients With Unresectable or Metastatic Kidney Cancer or Other Advanced Solid Tumors

Clear Cell Renal Cell Carcinoma | Recurrent Renal Cell Carcinoma | Stage III Renal Cell Cancer | Stage IV Renal Cell Cancer | Adult Solid Neoplasm

United States
Burzynski Research Institute

Terminated

Antineoplaston Therapy in Treating Patients With Metastatic or Unresectable Colon Cancer

Colon Cancer

United States
Southwest Oncology Group
National Cancer Institute (NCI)

Completed

S0202 Gemcitabine and Capecitabine for Unresectable Locally Advanced Metastatic Gallbladder Cancer or Cholangiocarcinoma

Gallbladder Cancer | Extrahepatic Bile Duct Cancer

United States
National Cancer Institute (NCI)

Completed

Trametinib or Combination Chemotherapy in Treating Patients With Refractory or Advanced Biliary or Gallbladder Cancer or That Cannot Be Removed by Surgery (S1310)

Hilar Cholangiocarcinoma | Advanced Adult Hepatocellular Carcinoma | Localized Non-Resectable Adult Liver Carcinoma | Recurrent Adult Liver Carcinoma | Recurrent Gallbladder Carcinoma | Stage IV Distal Bile Duct Cancer | Unresectable Extrahepatic Bile Duct Carcinoma | Stage II Gallbladder Cancer | Stage... and other conditions

United States
Alliance for Clinical Trials in Oncology
National Cancer Institute (NCI)

Completed

Sorafenib and Bevacizumab in Treating Patients With Metastatic Colorectal Cancer

Stage IV Colon Cancer | Stage IV Rectal Cancer | Recurrent Colon Cancer | Recurrent Rectal Cancer

United States
Alliance for Clinical Trials in Oncology
National Cancer Institute (NCI); Sanofi; Pfizer

Completed

Irinotecan, Oxaliplatin, and Capecitabine as First-Line Therapy in Treating Patients With Metastatic or Unresectable Locally Advanced Small Bowel Cancer

Recurrent Small Intestine Cancer | Small Intestine Adenocarcinoma

United States

Search clinical trials for: unresectable or recurrent colorectal cancer

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