Search clinical trials for: Long-term Safety

Total 45376 results

Eli Lilly and Company

Completed

Dose Escalation, Double-Blind Treatment With Duloxetine Hydrochloride Once Daily Dosing for Evaluation of Safety in Major Depression

Major Depressive Disorder

United States
Pfizer

Completed

Determine Long-Term Safety and Tolerability of Pregabalin in Patients With Anxiety Disorders.

Anxiety Neuroses

Spain, Belgium, South Africa, Germany, United Kingdom, Poland, Austria, Estonia, France, Israel, Italy, Latvia, Netherlands, Ukraine
Acusphere

Completed

Phase 3 Safety and Imaging Study of AI-700 in Patients With Suspected Coronary Artery Disease Undergoing Coronary Angiography

Coronary Artery Disease

United States
Acusphere

Completed

Phase 3 Imaging and Safety Study of AI-700 in Patients With Suspected Coronary Artery Disease Undergoing SPECT Imaging

Coronary Artery Disease

United States
National Institute of Neurological Disorders and...

Completed

Safety Study of Idebenone to Treat Friedreich's Ataxia

Friedreich Ataxia

United States
Assistance Publique - Hôpitaux de Paris

Completed

Safety Study of Thumb Orthoses in Osteoarthritis in the Base of the Thumb (BTOA)

Osteoarthritis
Lotus Pharmaceutical

Unknown

The Efficacy and Safety of Desloratadine With Levocetirizine in Treatment of Chronic Idiopathic Urticaria

Urticaria | Chronic Idiopathic Urticaria

Taiwan
DOV Pharmaceutical, Inc.

Completed

Efficacy and Safety of Bicifadine in the Treatment of Chronic Low Back Pain

Chronic Low Back Pain
Pfizer

Terminated

A Study to Evaluate the Efficacy and Safety of CP-101,606 in Subjects With an Acute Stroke

Stroke

United States, Italy, Spain, Singapore, Germany, Estonia, Portugal, Hungary
Sun Yat-sen University
Doublle Bioproduct Inc

Unknown

Safety and Efficacy of Adenoviral Endostatin in the Treatment of Advanced Solid Tumor

Advanced Solid Tumor

China
Nantes University Hospital

Terminated

Velcade Combined With High-Dose Dexamethasone in Patients With Newly Diagnosed Multiple Myeloma

Multiple Myeloma

France
National Cheng-Kung University Hospital

Unknown

A Double-Blind, Randomized, Parallel, Comparative Study to Evaluate the Efficacy and Safety of an Antidiabetic Agent Repaglinide for the Treatment of Type 2 Diabetes Mellitus Patients

Diabetes Mellitus, Type 2

Taiwan
University Hospital, Bonn
Medtronic

Completed

Safety of Cardiac Pacemakers in 1.5T Tesla MRI

Heart Diseases

Germany
Glycaemic Index Testing, Inc.
Sydney University Glycaemic Index Research Services; ILSI Europe

Completed

GI Interlab 2 Study: Measuring the Glycaemic Index (GI) of Foods

Healthy

United Kingdom, Australia, Canada, France, United States, China, Denmark, Finland, Germany, Italy, Malaysia, Netherlands, New Zealand, Philippines, South Africa, Sweden, Trinidad and Tobago
Novartis

Completed

A Study to Compare Ocular Safety and Tolerability of Prednisolone Acetate 0.5% Eye Drops Versus Vehicle in Healthy Volunteers

Healthy

Germany
University of Pernambuco

Unknown

Efficacy and Safety of Tadalafil in Hemodialysis Patients

Erectile Dysfunction

Brazil
Mahidol University

Unknown

Efficacy and Safety of Colistin for Therapy of Infections Caused by ESBL Producing K.Pneumoniae or E.Coli

Infections

Thailand
Nissan Chemical Industries

Completed

Efficacy and Safety of NM-702 Tablets for the Treatment of Intermittent Claudication

Intermittent Claudication | Peripheral Vascular Disease

United States
Mitsubishi Tanabe Pharma Corporation

Completed

Efficacy/Safety of Ecraprost in Lipid Emulsion for Treatment of Critical Leg Ischemia Due to Peripheral Arterial Disease

Peripheral Vascular Disease

United States, United Kingdom
Agency for Healthcare Research and Quality (AHRQ)

Unknown

Web Based Renal Transplant Patient Medication Education

Renal Transplant Recipients

United States
Sosei
Novartis

Completed

A Study to Assess the Safety and Efficacy of Different AD 237 Doses in Adults With COPD

COPD

Bulgaria, Poland, Hungary, Romania
University of Oslo School of Pharmacy

Completed

Efficacy and Safety of Nateglinide Treatment in Renal Transplant Recipients

Renal Transplant Recipients | Posttransplant Diabetes Mellitus | Posttransplant Impaired Glucose Tolerance

Norway
Premiere Oncology of Arizona
Genentech, Inc.

Unknown

Safety Study of Bevacizumab to Treat Women With a History of Breast Cancer and Suffering From Upper Extremity Lymphedema

Lymphedema

United States
University of British Columbia
Vancouver Coastal Health Research Institute; 3M

Completed

Safety and Efficacy of Imiquimod Applied in Dose-Cycle for Actinic Keratoses

Actinic Keratoses

Canada
Center for Primary Care and Public Health (Unisante)...
Swiss Tropical & Public Health Institute; Papua New Guinea Institute of Medical...

Terminated

Cotrifazid Safety and Efficacy Against Malaria

Clinical Malaria

Papua New Guinea
IDRI
Bill and Melinda Gates Foundation

Completed

Safety Study to Evaluate the Leish-111f + MPL-SE Vaccine in the Prevention of Cutaneous Leishmaniasis in Healthy Subjects Previously Exposed to the Leishmania Parasite

Cutaneous Leishmaniasis

Colombia
University of Oxford
Sanofi; AstraZeneca

Completed

Efficacy and Safety of Adding Clopidogrel to Aspirin or Use of Metoprolol in Myocardial Infarction

Acute Myocardial Infarction

China, United Kingdom
Eyetech Pharmaceuticals
Pfizer

Completed

A Clinical Trial to Explore Safety and Efficacy of Different Doses of Pegaptanib Sodium, Compared to Sham, in Patients With Wet AMD.

Age-Related Macular Degeneration
Purdue Pharma LP

Completed

The Safety and Efficacy of the Buprenorphine Transdermal Delivery System in Subjects With Osteoarthritis Pain.

Osteoarthritis

United States
Eyetech Pharmaceuticals
Pfizer

Completed

Study of the Safety, Tolerability and Pharmacokinetics of 1 Mg/Eye and 3 Mg/Eye Pegaptanib Sodium in Patients With Exudative Age-Related Macular Degeneration (AMD)

Age-Related Macular Degeneration
Purdue Pharma LP

Completed

The Safety and Efficacy of the Buprenorphine Transdermal Delivery System in Subjects With Chronic Back Pain.

Chronic Low Back Pain

United States
Purdue Pharma LP

Completed

Safety and Effectiveness of Buprenorphine Transdermal System in Elderly Subjects With Chronic Pain: Pilot Study.

Chronic Pain

United States
Purdue Pharma LP

Completed

Safety and Efficacy of the Buprenorphine Transdermal Delivery System in Subjects With Osteoarthritis Pain.

Osteoarthritis

United States
Zeria Pharmaceutical

Terminated

Safety and Tolerability of Z-100 in Patients With Early HIV Infection

HIV Infections

United States
Bavarian Nordic

Completed

Take Rate, Immunogenicity and Safety of Elstree-BN Smallpox Vaccine in Healthy Vaccinia-Naive Subjects

Smallpox

Germany
Purdue Pharma LP

Completed

Safety of the Buprenorphine Transdermal Delivery System in Subjects With Mod-to-Sev Pain Following Orthopedic Surgery.

Postoperative Pain

United States
Harras Pharma Curarina GmbH

Completed

Long-Term Effects of Sucontral(TM) on Mild and Moderate Cases of Diabetes Mellitus (Type 2)

Diabetes Mellitus, Type 2

Slovakia
Bukwang Pharmaceutical

Terminated

Safety and Antiviral Activity of Clevudine in Patients Infected With Hepatitis B Virus

Hepatitis B

Korea, Republic of
Celgene Corporation
Prologue Research International

Terminated

Phase I/II Open-Label, Dose Escalation Study To Determine The Maximum Tolerated Dose And To Evaluate The Safety Profile of Lenalidomide (Revlimid® CC-5013) With Liposomal Doxorubicin In Subjects With Advanced Ovarian and Primary Peritoneal Carcinoma

Ovarian Cancer

United States
Samaritan Pharmaceuticals, Inc

Completed

A Dose Response and Safety Study of Procaine HCl in HIV-Infected Patients

HIV Infections

United States
Nutrition 21, Inc.

Completed

A 30 Day Acute Efficacy and Safety Study of Chromium Picolinate + Biotin on Glycemic Control in Overweight or Obese Subjects With T2DM

Diabetes Mellitus, Type 2

United States
Critical Therapeutics

Terminated

CTI-01 (Ethyl Pyruvate) Safety and Complication Prevention in Cardiac Surgery Patients on Cardiopulmonary Bypass (CPB)

Coronary Disease | Heart Valve Diseases

United States
Otsuka Beijing Research Institute
Zhejiang Otsuka Pharmaceutical Co., Ltd.

Completed

Efficacy and Safety Study of Cilostazol to Prevent Reoccurrence of Stroke

Cerebral Infarction

China
Centers for Disease Control and Prevention

Unknown

Brief Intervention to Increase Safety Belt Use Among ED Patients

Accidents, Traffic
Schaper & Bruemmer GmbH & Co KG

Completed

Comparison of the Efficacy and Tolerability of Black Cohosh Vs Tibolone in Patients With Menopausal Symptoms

Menopause

China
PediaMed Pharmaceuticals

Unknown

Safety and Efficacy Study in the Treatment of Intestinal Problems Associated With Autism

Gastrointestinal Diseases | Signs and Symptoms, Digestive | Autistic Disorder | Child Development Disorders, Pervasive | Autism

United States
Tripler Army Medical Center

Unknown

Safety Study of Membrane Sweeping in Pregnancy

Pregnancy | Prelabor Rupture of Membranes

United States
Bellus Health Inc
FDA Office of Orphan Products Development

Completed

Study of the Safety and Efficacy of NC-503 in Secondary (AA) Amyloidosis

Gastrointestinal Diseases | Kidney Diseases | Rheumatoid Arthritis | Nephrotic Syndrome | Secondary (AA) Amyloidosis | Familial Mediterranean Syndrome

United States, Israel, Finland, France, Italy, Lithuania, Netherlands, Poland, Russian Federation, Spain, Turkey, United Kingdom
Nutrition 21, Inc.

Completed

Efficacy and Safety Study of Chromium Picolinate + Biotin on Glucose and Cholesterol Control in T2DM

Diabetes Mellitus, Type 2
MetaPhore Pharmaceuticals

Terminated

Pilot Study to Evaluate the Safety and Analgesic Activity of M40403 Co-Administered With an Opioid Agent for Cancer Pain

Pain | Cancer

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