Clinical Trials Sponsored by AFT Pharmaceuticals, Ltd

Total 4551 results

Idorsia Pharmaceuticals Ltd.

Completed

To Study the Effect of Aprocitentan on the Electrical Activity of the Heart in Healthy Men and Women

Healthy Subjects

Germany
Idorsia Pharmaceuticals Ltd.

Completed

The Effect of Reduced Liver Function on Selatogrel Pharmacokinetics

Healthy Subjects | Hepatic Impairment

Germany
Idorsia Pharmaceuticals Ltd.

Completed

To Study the Effect of Cenerimod on the Electrical Activity of the Heart, in Men and Women. To Study the Effect of Cenerimod on the Use of Oral Contraceptives in Women. To Study the Effect That Charcoal Has on the Elimination of Cenerimod From the Body, in Women and Men.

Healthy Subjects

France
Idorsia Pharmaceuticals Ltd.

Completed

A Study to Investigate the Effect of Itraconazole on the Way the Body Absorbs, Distributes, and Gets Rid of ACT-1004-1239 Given as a Single Dose of 10 mg to Healthy Male Subjects

Healthy

Portugal
Neurim Pharmaceuticals Ltd.

Withdrawn

Efficacy and Safety of Slenyto for Insomnia in Children With ASD (ASD)

Autism Spectrum Disorder
Idorsia Pharmaceuticals Ltd.

Completed

Study of the Way the Body Takes up, Distributes, and Gets Rid of ACT-541468 in Subjects With Abnormal Kidney Function Compared to Healthy Subjects

Healthy | Renal Insufficiency

Germany
Avraham Pharmaceuticals Ltd

Completed

Safety and Efficacy Study of Ladostigil in Mild to Moderate Probable Alzheimer's Disease

Cognitive Impairment | Dementia | Alzheimer's Disease | Memory Loss

Austria, Croatia, Germany, Serbia, Spain
Clarity Pharmaceuticals Ltd

Completed

An Imaging Study of 64Cu-SARTATE Using Positron Emission Tomography in Patients With Neuroendocrine Tumours

Neuroendocrine Tumors
Idorsia Pharmaceuticals Ltd.

Completed

Single Oral Dose of 4 mg Cenerimod in Healthy Japanese and Caucasian Subjects

Healthy Volunteers

United States
Idorsia Pharmaceuticals Ltd.

Completed

Efficacy and Safety of ACT-541468 in Elderly Subjects With Insomnia Disorder

Insomnia Disorder

United States, Germany
Idorsia Pharmaceuticals Ltd.

Completed

Clinical Study to Investigate the Biological Activity, Safety, Tolerability, and Pharmacokinetics of ACT-334441 in Subjects With Systemic Lupus Erythematosus

Systemic Lupus Erythematosus

United States, Belarus, Bulgaria, Georgia, Russian Federation, Ukraine
Idorsia Pharmaceuticals Ltd.

Completed

A Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Single Ascending Doses of ACT-1004-1239 in Healthy Male Subjects

Healthy

United States
Idorsia Pharmaceuticals Ltd.

Completed

A Study to Evaluate the Effects of ACT-541468 on Respiration in Patients With Moderate Chronic Obstructive Pulmonary Disease

Chronic Obstructive Pulmonary Disease

Germany
Idorsia Pharmaceuticals Ltd.

Completed

Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of ACT-451840 in Healthy Subjects (Part A)

Healthy

France
Idorsia Pharmaceuticals Ltd.

Completed

Study to Validate the Questionnaire Called IDSIQ™ in Patients With Insomnia Disorder

Insomnia Disorder

United States, Germany
Atlantic Pharmaceuticals Ltd

Completed

Phase 1 Food Effect Study for Alicaforsen Tablets

IBD

United Kingdom
Idorsia Pharmaceuticals Ltd.

Completed

A Study in Healthy Male Subjects to Investigate Whether Administration of Rifampicin Can Affect the Fate of Clazosentan in the Body of Clazosentan

Healthy Subjects

Netherlands
Idorsia Pharmaceuticals Ltd.

Completed

Essential Hypertension (REDUCE-1)

Essential Hypertension

Israel, Serbia
Idorsia Pharmaceuticals Ltd.

Completed

A Study to Assess the Tolerability, Safety, Pharmacodynamics, and Pharmacokinetics of Ascending Single Doses (Including Food Interaction) and Ascending Multiple Doses of ACT-453859, and Multiple Doses of Setipiprant (ACT-129968)

Healthy
Idorsia Pharmaceuticals Ltd.

Completed

Clinical Study to Assess the Pharmacokinetics, Safety, and Tolerability of ACT-129968 in Healthy Subjects

Healthy Subjects

Germany
Idorsia Pharmaceuticals Ltd.

Completed

A Study of ACT-541468 in Healthy Japanese and Caucasian Subjects

Healthy Subjects

Netherlands
Idorsia Pharmaceuticals Ltd.

Completed

A Study to Investigate the Safety, Tolerability, Pharmacokinetics (PK), and Pharmacodynamics (PD) of ACT-541468 in Healthy Young Adults and Elderly Subjects

Healthy Subjects

Netherlands
Idorsia Pharmaceuticals Ltd.

Completed

A Study Conducted in Healthy Male Subjects to Investigate the Safety and Tolerability of AC-76, Its Fate in the Body, and Its Effect on the Body

Healthy Subjects

United States
Idorsia Pharmaceuticals Ltd.

Completed

Tezosentan in Acute Heart Failure (VERITAS 1)

Acute Heart Failure | Acute Decompensation of Chronic Heart Failure | New Onset of Heart Failure

United States, United Kingdom, Israel, Switzerland, Austria, Denmark, France, Germany, Greece, Poland
Idorsia Pharmaceuticals Ltd.

Completed

Clinical Study to Explore the Efficacy of ACT-129968 in Patients With Partly Controlled Asthma (CONTROL)

Asthma

United States, Australia, Bulgaria, Germany, Hungary, Israel, Poland, Russian Federation, Serbia, Singapore, South Africa, Sweden, Ukraine
Idorsia Pharmaceuticals Ltd.

Completed

Pharmacokinetic Interaction Between Midazolam and ID-082 in Healthy Subjects

Healthy

United Kingdom
Neurim Pharmaceuticals Ltd.

Completed

Efficacy and Safety of Circadin® 2 mg in the Treatment of Primary Insomnia Patients

Primary Insomnia

United Kingdom
Avraham Pharmaceuticals Ltd

Completed

A 3 Year Study to Evaluate the Safety and Efficacy of Low Dose Ladostigil in Patients With Mild Cognitive Impairment

Dementia | Mild Cognitive Impairment

Germany, Austria, Israel
BiondVax Pharmaceuticals ltd.

Completed

Phase II Study to Assess Safety & Immunogenicity of Multimeric-001 Influenza Vaccine, Followed by TIV (BVX006)

Influenza

Israel
Faron Pharmaceuticals Ltd

Completed

Safety, Tolerability and Preliminary Efficacy of FP-1201 in ALI and ARDS. Phase I/II

Acute Respiratory Distress Syndrome | Acute Lung Injury

United Kingdom
BiondVax Pharmaceuticals ltd.

Completed

A Study to Assess the Safety and Immunogenicity of M-001 Influenza Vaccine as a Primer to TIV in Elderly Volunteers

Healthy | Influenza

Israel
BiondVax Pharmaceuticals ltd.

Completed

A Double-Dose Safety Study of An Influenza Vaccine (Multimeric-001) Injected to Elderly Volunteers

Influenza

Israel
Sauflon Pharmaceuticals Ltd

Completed

Clinical Performance of All-in-One Light Multi-purpose for Silicone Hydrogel Contact Lenses

Healthy

United Kingdom
Neurim Pharmaceuticals Ltd.

Completed

Sleep Inducing And Maintaining Efficacy Of Circadin In Elderly Insomniacs (Neu I)

Primary Insomnia

France
Corbus Pharmaceuticals Inc.
CSPC Zhongnuo Pharmaceutical (Shijiazhuang) Co., Ltd.

Recruiting

A Phase 1/2 Study to Investigate CRB-701 in Solid Tumors

Solid Tumor, Adult

United States, Spain, Turkey, United Kingdom
MingSight Pharmaceuticals, Inc
Shenzhen MingSight Relin Pharmaceutical Co., Ltd

Recruiting

A Study of MS-553 in Patients With Relapsed or Refractory B-cell Lymphoma

Chronic Lymphocytic Leukemia (CLL) | Small Lymphocytic Lymphoma (SLL) | Mantle Cell Lymphoma (MCL) | Diffuse Large B-cell Lymphoma (DLBCL) | Follicular Lymphoma (FL) | Relapsed or Refractory B-cell Lymphoma | Marginal Zone Lymphoma (MZL)

China
Ascentawits Pharmaceuticals, Ltd

Recruiting

A Phase I/II Study of AST-3424 in Subjects With Advanced Solid Tumors

Hepatocellular Carcinoma | Advanced Solid Tumors

China
AVVA Pharmaceuticals Ltd.

Recruiting

Efficacy of the Dietary Food Supplement ALCOFILTRUM in Alleviating Alcohol Hangover Symptoms

Alcohol Drinking | Alcohol Intoxication

Belarus
Idorsia Pharmaceuticals Ltd.

Recruiting

A Research Study to Evaluate the Efficacy and Safety of Cenerimod in Subjects Suffering From Systemic Lupus Erythematosus (OPUS-2)

Lupus Erythematosus, Systemic

Spain, United States, Georgia, Serbia, Germany, Portugal, Poland, South Africa, Philippines, Czechia, Puerto Rico, Chile, Japan, Peru
Britannia Pharmaceuticals Ltd.

Recruiting

Long-Term Observational Study on Effectiveness and Safety of Lecigon in Patients With Advanced Parkinson's Disease (ELEGANCE)

Advanced Parkinson Disease

Germany, Spain, Austria, Croatia, Romania, Slovenia, Belgium, Bulgaria, Czechia, Hungary, Ireland, Netherlands, Sweden
Clarity Pharmaceuticals Ltd

Recruiting

64Cu-SAR-bisPSMA and 67Cu-SAR-bisPSMA for Identification and Treatment of PSMA-expressing Metastatic Castrate Resistant Prostate Cancer (SECuRE) (SECuRE)

Prostatic Neoplasms, Castration-Resistant

United States
Fochon Pharmaceuticals, Ltd.

Recruiting

A Safety and Tolerability Study of FCN-207 in Healthy Volunteers

Hyperuricemia

China
Orasis Pharmaceuticals Ltd.

Completed

An Evaluation of the Efficacy and Safety of CSF-1 in the Temporary Correction of Presbyopia (NEAR-2) (NEAR-2)

Presbyopia

United States
Orasis Pharmaceuticals Ltd.

Completed

An Evaluation of the Efficacy and Safety of CSF-1 in the Temporary Correction of Presbyopia (NEAR-1) (NEAR-1)

Presbyopia

United States
Kiniksa Pharmaceuticals, Ltd.

Active, not recruiting

Study to Assess the Safety, Pharmacokinetics, and Efficacy of KPL-404 in Participants With Rheumatoid Arthritis With Inadequate Response or Intolerance to at Least One Biologic Disease-modifying Anti-rheumatic Drug or a Janus Kinase Inhibitor

Arthritis, Rheumatoid

United States, Poland, Hungary, Georgia, Czechia, South Africa, Bulgaria
Idorsia Pharmaceuticals Ltd.

Completed

Clinical Research Study With Clazosentan to Evaluate Its Effects on Preventing Complications Due to the Narrowing of the Blood Vessels (Vasospasm) in the Brain, Caused by Bleeding Onto the Surface of the Brain (REACT)

Aneurysmal Subarachnoid Hemorrhage

United States, Spain, Israel, Finland, Poland, Austria, Belgium, Canada, Czechia, Denmark, France, Germany, Hungary, Italy, Sweden
Kiniksa Pharmaceuticals, Ltd.

Completed

Study to Assess the Efficacy, Safety, and Tolerability of Vixarelimab in Reducing Pruritus in Prurigo Nodularis

Prurigo Nodularis | Pruritis

United States, Australia, Austria, Belgium, Canada, Czechia, France, Germany, Italy, Korea, Republic of, Poland, Taiwan, United Kingdom
Idorsia Pharmaceuticals Ltd.

Completed

Efficacy and Safety of Four Doses of Cenerimod Compared to Placebo in Adult Subjects With Active Systemic Lupus Erythematosus

Systemic Lupus Erythematosus

Spain, United States, Italy, Taiwan, Thailand, Poland, Russian Federation, Israel, Ukraine, Mexico, Philippines, Georgia, United Kingdom, Chile, France, Bulgaria, Czechia, Greece, Hungary, Romania, Turkey, Germany, Puerto Rico, Japan
Clarity Pharmaceuticals Ltd

Completed

64Cu-SAR-bisPSMA for Identification of Participants With Recurrence of Prostate Cancer (COBRA) (COBRA)

Biochemical Recurrence of Malignant Neoplasm of Prostate

United States
Faron Pharmaceuticals Ltd

Terminated

Human Intravenous Interferon Beta-Ia Safety and Preliminary Efficacy in Hospitalized Subjects With COVID-19 (HIBISCUS)

Covid19

United States

3

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