Clinical Trials Sponsored by CEN Biotech

Total 7372 results

CHEN Yajun

Enrolling by invitation

Prospective Cohort Study on Cognition and Cardiovascular Disease of Sedentary Behaviors in Children

Sedentary Behavior;Cognition;Cardiovascular-related Disease
BioNTech Research & Development, Inc.

Recruiting

Study of HuMab-5B1 (MVT-5873) in Subjects With Pancreatic Cancer or Other Cancer Antigen 19-9 (CA19-9) Positive Malignancies

Pancreatic Cancer

United States
BioNTech RNA Pharmaceuticals GmbH

Completed

RBL001/RBL002 Phase I Clinical Trial (MERIT)

Melanoma

Austria, Germany
BioNTech Research & Development, Inc.

Terminated

Study of 177Lu Human Monoclonal Antibody 5B1 (MVT-1075) in Combination With a Blocking Dose of MVT-5873 as Radioimmunotherapy

Pancreatic Carcinoma | Tumors That Express CA 19-9

United States
Guangzhou Patronus Biotech Co., Ltd.
Yantai Patronus Biotech Co., Ltd.

Not yet recruiting

Safety and Immunogenicity of Recombinant COVID-19 Trivalent Protein Vaccine （CHO Cell）LYB002V14 in Booster Vaccination

SARS-CoV-2 | COVID-19 Vaccine

China
Guangzhou Patronus Biotech Co., Ltd.
Yantai Patronus Biotech Co., Ltd.

Active, not recruiting

Safety and Immunogenicity of COVID-19 Vaccine in Population Aged 18 Years and Above

COVID-19

China
BioNTech SE

Recruiting

A Clinical Trial in Healthy Volunteers to Study the Safety, Tolerability, and Immune Responses After Vaccination With an Investigational Vaccine Designed to Prevent Genital Herpes Lesions

Genital Herpes Simplex Type 2

United States
XBiotech, Inc.

Recruiting

Natrunix or Placebo in Combination With Methotrexate in Rheumatoid Arthritis

Rheumatoid Arthritis

United States
XBiotech, Inc.

Not yet recruiting

Natrunix Versus Methotrexate in Rheumatoid Arthritis

Rheumatoid Arthritis
BioNTech SE

Recruiting

Safety and Preliminary Efficacy Trial of BNT142 in Patients With CLDN6-positive Solid Tumors

Solid Tumor

United States, Spain, Singapore, United Kingdom
BioNTech SE

Recruiting

Clinical Trial Evaluating the Safety, Tolerability and Preliminary Efficacy of BNT116 Alone and in Combinations in Patients With Advanced Non-small Cell Lung Cancer (LuCa-MERIT-1)

Non-Small Cell Lung Cancer

Spain, Germany, Turkey, United States, Hungary, United Kingdom, Poland
BioNTech SE

Recruiting

Dose Escalation Trial of BNT152+153 in Patients With Cancer

Solid Tumor

United States, Czechia
BioNTech SE

Active, not recruiting

Safety, Pharmacokinetics, Pharmacodynamics, and Preliminary Efficacy Trial of BNT411

Solid Tumor | Extensive-stage Small Cell Lung Cancer

United States, Spain, United Kingdom, Germany
BioNTech SE

Active, not recruiting

Safety and Immune Responses After Vaccination With an Investigational RNA-based Vaccine Against Malaria

Malaria

United States
BioNTech SE

Terminated

PRO-MERIT (Prostate Cancer Messenger RNA Immunotherapy) (PRO-MERIT)

Prostate Cancer

United States, Germany, United Kingdom, Hungary
XBiotech, Inc.

Active, not recruiting

Hutrukin to Analyze Safety and PK in Healthy Volunteers

Pharmacokinetics

United States
XBiotech, Inc.

Active, not recruiting

XB2001 in Combination With ONIVYDE + 5-FU/LV (+Folinic Acid) in Advanced Pancreatic Cancer (1-BETTER)

Pancreatic Cancer

United States
BioNTech SE

Completed

A Trial Investigating the Safety and Effects of One or Two Additional Doses of Comirnaty or One Dose of BNT162b2s01 in BNT162-01 or BNT162-04 Trial Subjects

COVID-19 | SARS-CoV-2 Infection

Germany
Guangzhou Patronus Biotech Co., Ltd.
Yantai Patronus Biotech Co., Ltd.

Not yet recruiting

A Safety and Immunogenicity Trial of the Recombinant Zoster Vaccine （CHO Cell）, LYB004 in Adults Aged 50 to 70 Years

Herpes Zoster

Australia
SOTIO Biotech AG
Merck Sharp & Dohme LLC

Active, not recruiting

A Study of SOT101 in Combination With Pembrolizumab to Evaluate the Efficacy and Safety in Patients With Selected Advanced Solid Tumors

Hepatocellular Carcinoma | Colorectal Cancer | Ovarian Cancer | Non-Small Cell Lung Cancer | Castration-resistant Prostate Cancer | Cutaneous Squamous Cell Carcinoma

Italy, Spain, France, Belgium, Czechia, United States, Poland, Georgia, Hungary
Guangzhou Patronus Biotech Co., Ltd.
Yantai Patronus Biotech Co., Ltd.

Terminated

Efficacy and Safety of COVID-19 Vaccine as Booster Vaccination in Adults 18 Years of Age or Older

COVID-19

China
Guangzhou Patronus Biotech Co., Ltd.
Yantai Patronus Biotech Co., Ltd.

Withdrawn

Immunogenicity and Safety of COVID-19 Vaccine in Population Aged 18 Years and Above

COVID-19

China
BioNTech SE

Recruiting

Safety, Tolerability, and Efficacy of mFOLFIRINOX ± BNT321 as Adjuvant Therapy Following Curative Resection in Patients With Pancreatic Adenocarcinoma

Pancreatic Cancer

United States
BioNTech SE

Recruiting

A Clinical Study Investigating the Safety and Immune Responses After Immunization With Investigational Monkeypox Vaccines

Monkeypox

United Kingdom, United States
XBiotech, Inc.

Recruiting

Natrunix Safety PK Study in Healthy Volunteers

Pharmacokinetics

United States
BioNTech SE

Recruiting

Epidemiological Study to Monitor Study Participants With Resected Stage II (High Risk) or Stage III Colorectal Cancer for Circulating Tumor DNA Before, During and After Their Treatment With Adjuvant Chemotherapy

Colorectal Cancer Stage II | Colorectal Cancer Stage III

United States, Spain, Germany, Belgium
BioNTech SE

Active, not recruiting

BNT151 as a Monotherapy and in Combination With Other Anti-cancer Agents in Patients With Solid Tumors

Solid Tumor

United States, Spain
BioNTech RNA Pharmaceuticals GmbH

Completed

IVAC MUTANOME Phase I Clinical Trial

Melanoma

Austria, Germany
Sunhawk Vision Biotech, Inc.

Not yet recruiting

Efficacy and Safety of SHJ002 Ophthalmic Solution in the Treatment of Corneal Erosion in Sjogren's Patients

Corneal Erosion

Taiwan
Biotech Pharmaceutical Co., Ltd.

Not yet recruiting

Nimotuzumab Combined With Paclitaxel for Recurrent Metastatic Gastric or Esophagogastric Junction Adenocarcinoma (NOTABLE-307)

Gastric or Esophagogastric Junction Adenocarcinoma
Biotech Pharmaceutical Co., Ltd.

Not yet recruiting

Safety and Preliminary Clinical Activity of Itolizumab in ARDS

Acute Respiratory Distress Syndrome
Metro International Biotech, LLC

Recruiting

Effects of MIB-626 With and Without A High-Intensity Multi-Dimensional Exercise Training Program

Healthy

United States
SunWay Biotech Co., LTD.

Recruiting

Effect of Vigiis 101 Lactic Acid Bacteria Powder on Body Weight and Body Fat in Overweight Participants

Overweight | Body Weight | Body Fat

Taiwan
Sinovac Biotech Co., Ltd

Recruiting

A Multi-center, Open-labelled, Randomized, Controlled, Extended Phase Ⅲ Clinical Trial of sIPV Vaccine

Poliomyelitis | Polio

Pakistan, Bangladesh
Legend Biotech USA Inc

Recruiting

DLL3-Directed Chimeric Antigen Receptor T-cells in Subjects With Extensive Stage Small Cell Lung Cancer

Small Cell Lung Cancer Extensive Stage | Large Cell Neuroendocrine Carcinoma of the Lung

United States
Hangzhou Jiayin Biotech Ltd

Recruiting

Clinical Trial to Assess the Safety and Efficacy of EXG001-307 in Patients With Spinal Muscular Atrophy Type 1

Spinal Muscular Atrophy Type I

China
Noile-Immune Biotech, Inc

Recruiting

Study of NIB101 in Participants With Advanced Solid Tumors

Solid Tumor

Japan
Quanta Medical
Cousin Biotech

Recruiting

Study of the Effectiveness of a Polymer Cerclage System Compared to Cerclages Used in Standard Care (CERCPMCF) ) (SERRE)

Femoral Fracture

France
Oneness Biotech Co., Ltd.

Recruiting

Evaluate the Efficacy and Safety of FB704A in Adult With Severe Asthma

Severe Asthma

Taiwan
Oneness Biotech Co., Ltd.

Recruiting

Evaluate the Safety and Efficacy of ON101 Cream for the Treatment of Chronic Diabetic Foot Ulcers

Chronic Diabetic Foot Ulcers

United States
Meridigen Biotech Co., Ltd.

Recruiting

Mesenchymal Stem Cells for The Treatment of Knee Osteoarthritis (KOA).

Osteoarthritis, Knee

Taiwan
Quanta Medical
Cousin Biotech

Recruiting

Efficacy and Safety of IntraSPINE® Associated With Discectomy in the Treatment of Lumbar Disc Herniation. (INTREUR)

Disk Herniated Lumbar

France
Quanta Medical
Cousin Biotech

Recruiting

Safety and Efficacy Study of USTRAP™ in Male Urinary Incontinence (PROSPECT)

Urinary Incontinence

France
Oneness Biotech Co., Ltd.

Recruiting

Evaluate Safety, Tolerability, PK, Preliminary Clinical Activity of OB318 in Patients With Advanced Solid Malignancies

Advanced Solid Malignancies

Taiwan
Eusol Biotech Co., Ltd.

Suspended

A Multicenter, Randomized, Double-blind, Placebo-controlled Phase 3 Study to Evaluate the Safety and Efficacy of ES135 in Subjects With Spinal Cord Injury

Spinal Cord Injuries

Taiwan
A-Mansia Biotech S.A.

Completed

Effect of Pasteurized Akkermansia Muciniphila on Insulin Resistance in Otherwise Healthy Subjects With Dysglycaemia

Metabolic Syndrome | Overweight and Obesity | Pre-diabetes

Ireland, Germany
Metro International Biotech, LLC

Completed

Phase 2a MIB-626 vs. Placebo COVID-19

Covid19 | Stage 1 Acute Kidney Injury

United States
4Moving Biotech

Completed

Safety, Tolerability and Pharmacokinetics of Intra-articular (IA) Single Ascending Dose of 4P-004 in Patient With Kellgren and Lawrence Grade 2 to 4 Osteoarthritic (OA) Knee (LASARE)

Knee Osteoarthritis

Belgium
Dreamhawk Vision Biotech, Inc.

Completed

Phase II Study of SHJ002 Sterile Ophthalmic Solution Compared With Vehicle in Participants With Dry Eye Disease

Dry Eye Disease

Thailand, Australia, Taiwan
Meridigen Biotech Co., Ltd.

Active, not recruiting

Mesenchymal Stem Cells for The Treatment of Chronic Obstructive Pulmonary Disease

Chronic Obstructive Pulmonary Disease Moderate

Taiwan

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