Clinical Trials Sponsored by Children's Discovery Institute

Total 2466 results

Children's Oncology Group
National Cancer Institute (NCI)

Completed

Combination Chemotherapy With or Without Gemtuzumab in Treating Young Patients With Newly Diagnosed Acute Myeloid Leukemia

Leukemia

United States, Canada, Australia, Switzerland, New Zealand, Puerto Rico
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Combination Chemotherapy Alone or With Radiation Therapy in Treating Children With Kidney Cancer

Kidney Cancer

United States, Canada, Puerto Rico, Australia, Netherlands, New Zealand, Switzerland
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Levofloxacin in Preventing Infection in Young Patients With Acute Leukemia Receiving Chemotherapy or Undergoing Stem Cell Transplantation

Diarrhea | Fungal Infection | Neutropenia | Secondary Acute Myeloid Leukemia | Recurrent Childhood Acute Lymphoblastic Leukemia | Recurrent Childhood Acute Myeloid Leukemia | Bacterial Infection | Acute Leukemias of Ambiguous Lineage | Musculoskeletal Complications | Untreated Childhood Acute Myeloid Leukemia...

United States, Canada
Seattle Children's Hospital
National Cancer Institute (NCI)

Completed

Preschoolers Learning and Active in PlaY (PLAY)

Physical Activity

United States
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Study to Assess Compliance With Long-Term Mercaptopurine Treatment in Young Patients With Acute Lymphoblastic Leukemia in Remission

Childhood Acute Lymphoblastic Leukemia in Remission

United States, Canada, Australia
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Donor Stem Cell Transplant in Treating Young Patients With Acute Myeloid Leukemia With Monosomy 7, -5/5q-, High FLT3-ITD AR, or Refractory or Relapsed Acute Myelogenous Leukemia

Leukemia

United States, Canada
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Collection of Bone Marrow From Donors Treated With or Without Filgrastim

No Evidence of Disease | Healthy Stem Cell Donor

United States
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Tacrolimus and Methotrexate With or Without Sirolimus in Preventing Graft-Versus-Host Disease in Young Patients Undergoing Donor Stem Cell Transplant for Acute Lymphoblastic Leukemia in Complete Remission

Childhood Acute Lymphoblastic Leukemia in Remission | Graft Versus Host Disease | B-cell Childhood Acute Lymphoblastic Leukemia | L1 Childhood Acute Lymphoblastic Leukemia | L2 Childhood Acute Lymphoblastic Leukemia | T-cell Childhood Acute Lymphoblastic Leukemia

United States, Canada, Australia
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Combination Chemotx in Treating Children or Adolescents With Newly Diagnosed Stg III or Stg IV Lymphoblastic Lymphoma

Lymphoma

United States, Canada, Australia, Switzerland, Puerto Rico
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Erwinia Asparaginase After Allergy to PEG-Asparaginase in Treating Young Patients With Acute Lymphoblastic Leukemia

Childhood Acute Lymphoblastic Leukemia | Adult Acute Lymphoblastic Leukemia

United States
Seattle Children's Hospital
National Cancer Institute (NCI)

Terminated

Combination Chemotherapy and Peripheral Stem Cell Transplantation in Treating Patients With Recurrent or Refractory Solid Tumors

Unspecified Childhood Solid Tumor, Protocol Specific

United States
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Genetic Susceptibility Biomarkers in Children With Neuroblastoma (Also Known as Neuroblastoma Epidemiology in North America [NENA])

Neuroblastoma

United States, Canada
Nationwide Children's Hospital
Stanley Medical Research Institute

Completed

Controlled Trial of Valproate Versus Risperidone in Young Children With Bipolar Disorder

Bipolar Disorder
Steven J. Hardy

Completed

Feasibility and Efficacy of a Home-based, Computerized Cognitive Training Program in Pediatric Sickle Cell Disease

Anemia, Sickle Cell

United States
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Trabectedin in Treating Young Patients With Recurrent or Refractory Soft Tissue Sarcoma or Ewing's Family of Tumors

Recurrent Ewing Sarcoma | Recurrent Childhood Rhabdomyosarcoma | Previously Treated Childhood Rhabdomyosarcoma | Recurrent Childhood Soft Tissue Sarcoma | Peripheral Primitive Neuroectodermal Tumor

United States, Canada
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Combination Chemotherapy in Treating Young Patients With Recurrent or Resistant Malignant Germ Cell Tumors

Testicular Yolk Sac Tumor | Recurrent Ovarian Germ Cell Tumor | Recurrent Childhood Malignant Germ Cell Tumor | Recurrent Malignant Testicular Germ Cell Tumor | Childhood Extracranial Germ Cell Tumor | Childhood Malignant Ovarian Germ Cell Tumor | Childhood Malignant Testicular Germ Cell Tumor | Ovarian... and other conditions

United States, Canada, Australia, Puerto Rico
Children's Oncology Group
National Cancer Institute (NCI)

Withdrawn

Imetelstat Sodium in Treating Younger Patients With Relapsed or Refractory Solid Tumors

Rhabdomyosarcoma | Recurrent Neuroblastoma | Recurrent Osteosarcoma | Hepatoblastoma | Recurrent Childhood Rhabdomyosarcoma | Previously Treated Childhood Rhabdomyosarcoma | Recurrent Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor | Recurrent Childhood Liver Cancer
Children's Oncology Group
National Cancer Institute (NCI)

Withdrawn

Studying Body Mass Index in Younger Patients Who Are Receiving Treatment for High-Risk Acute Lymphoblastic Leukemia

Acute Lymphoblastic Leukemia | Untreated Childhood Acute Lymphoblastic Leukemia

United States
Children's Oncology Group
National Cancer Institute (NCI)

Withdrawn

Palifermin in Preventing Oral Mucositis Caused by Chemotherapy and/or Radiation Therapy in Young Patients Undergoing Stem Cell Transplant

Malignant Neoplasm | Gastrointestinal Mucositis
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Genetic Analysis Using Blood or Bone Marrow From Participants With Neuroblastoma or Noncancerous Conditions

Recurrent Neuroblastoma | Localized Resectable Neuroblastoma | Localized Unresectable Neuroblastoma | Regional Neuroblastoma | Stage 4 Neuroblastoma

United States
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Collecting and Storing Malignant, Borderline Malignant Neoplasms, and Related Samples From Young Patients With Cancer

Juvenile Myelomonocytic Leukemia | Chronic Lymphocytic Leukemia | Secondary Acute Myeloid Leukemia | Childhood Acute Lymphoblastic Leukemia | Prolymphocytic Leukemia | Hairy Cell Leukemia | Acute Undifferentiated Leukemia | Atypical Chronic Myeloid Leukemia, BCR-ABL1 Negative | Childhood Acute Myeloid... and other conditions

United States, Canada, Australia, New Zealand, Puerto Rico, Switzerland
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Etanercept in Treating Young Patients With Idiopathic Pneumonia Syndrome After Undergoing a Donor Stem Cell Transplant

Juvenile Myelomonocytic Leukemia | Secondary Acute Myeloid Leukemia | Childhood Acute Myeloid Leukemia in Remission | Accelerated Phase Chronic Myelogenous Leukemia | Childhood Acute Lymphoblastic Leukemia in Remission | Childhood Chronic Myelogenous Leukemia | Childhood Myelodysplastic Syndromes and other conditions

United States
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Brain Function in Young Patients Receiving Methotrexate for Acute Lymphoblastic Leukemia

Untreated Childhood Acute Lymphoblastic Leukemia | Childhood T Acute Lymphoblastic Leukemia | Neurotoxicity Syndrome | Childhood B Acute Lymphoblastic Leukemia | Cognitive Side Effects of Cancer Therapy | Psychological Impact of Cancer | Long-Term Effects Secondary to Cancer Therapy in Children

United States, Canada, Australia, New Zealand
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Evaluating Dactinomycin and Vincristine in Young Patients With Cancer

Unspecified Childhood Solid Tumor, Protocol Specific | Ewing Sarcoma of Bone | Ewing Sarcoma | Childhood Acute Lymphoblastic Leukemia | Wilms Tumor and Other Childhood Kidney Tumors | Childhood Rhabdomyosarcoma | Childhood Soft Tissue Sarcoma | Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor...

United States, Australia, Canada
Children's Oncology Group
National Cancer Institute (NCI)

Completed

DNA Analysis of Bone Marrow and Blood Samples From Young Patients With Acute Myeloid Leukemia or Acute Lymphoblastic Leukemia

Leukemia
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Assessing Ear Damage in Young Cancer Patients Treated With Cisplatin

Unspecified Childhood Solid Tumor, Protocol Specific | Ototoxicity

Canada, United States, Australia
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Natural History Study of Infants With Adrenal Masses Found on Prenatal and/or Neonatal Imaging

Precancerous Condition | Adrenocortical Carcinoma | Localized Resectable Neuroblastoma

United States, Canada, Australia
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Gene Analysis in Studying Susceptibility to Wilms Tumor

Recurrent Childhood Kidney Neoplasm | Stage I Kidney Wilms Tumor | Stage II Kidney Wilms Tumor | Stage III Kidney Wilms Tumor | Stage IV Kidney Wilms Tumor

United States
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Biomarker Differences in Samples From Patients With Undifferentiated Sarcomas

Soft Tissue Sarcoma

United States
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Studying Mechanisms of Radiation Therapy Resistance in Samples From Younger Patients With Rhabdomyosarcoma

Recurrent Childhood Rhabdomyosarcoma | Previously Treated Childhood Rhabdomyosarcoma | Alveolar Childhood Rhabdomyosarcoma | Embryonal Childhood Rhabdomyosarcoma | Previously Untreated Childhood Rhabdomyosarcoma

United States
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Studying Biomarkers in Samples From Younger Patients With Wilms Tumor

Kidney Cancer
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Biomarkers in DNA Samples From Patients With High-Risk Acute Lymphoblastic Leukemia

Leukemia
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Comparison of Laboratory Test Results of Minimal-Residual Disease in Samples From Patients With Acute Myeloid Leukemia

Leukemia
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Biomarker Expression in Samples From Young Patients With Anaplastic Large Cell Lymphoma

Lymphoma
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Study of Gemtuzumab Ozogamicin Therapy in DNA Samples From Patients With Acute Myeloid Leukemia Treated on COG-AAML0531

Leukemia
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Biomarker in Tumor Tissue Samples From Patients With Rhabdomyosarcoma

Sarcoma
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Cell Samples From Patients With Leukemia

Leukemia
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Genetic Test in Detecting Minimal Residual Disease in Samples From Younger Patients Registered on the COG-AALL08B1 Trial

Leukemia
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Biomarkers in Patients With Rhabdomyosarcoma

Sarcoma
Children's Oncology Group
National Cancer Institute (NCI)

Completed

DNA Variations in the Gene in Young Patients With Wilms' Tumor

Kidney Cancer

United States, Canada, Puerto Rico, Australia, Netherlands, Switzerland, New Zealand
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Biomarkers in Bone Marrow Samples From Pediatric Patients With High-Risk Acute Myeloid Leukemia

Childhood Acute Erythroleukemia (M6) | Childhood Acute Megakaryocytic Leukemia (M7) | Childhood Acute Monoblastic Leukemia (M5a) | Childhood Acute Monocytic Leukemia (M5b) | Childhood Acute Myeloblastic Leukemia With Maturation (M2) | Childhood Acute Myeloblastic Leukemia Without Maturation... and other conditions

United States
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Studying Gene Expression in Samples From Younger Patients With Neuroblastoma

Neuroblastoma | Neoplastic Syndrome
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Obatoclax Mesylate in Samples From Young Patients With Acute Myeloid Leukemia

Leukemia
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Genetic Test To Identify Previously Undetectable Minimal Residual Disease in Cell Samples From Younger Patients With Acute Lymphoblastic Leukemia

Leukemia
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Biomarkers in DNA Samples From Younger Patients With Newly Diagnosed Acute Myeloid Leukemia Receiving Gemtuzumab Ozogamicin

Leukemia
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Biomarkers in Samples From Young Patients With Acute Myeloid Leukemia

Leukemia
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Biomarkers in Predicting Response to Treatment in Bone Marrow Samples From Young Patients With Acute Myeloid Leukemia

Leukemia
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Role of Biomarkers in Disease Progression in Samples From Patients With Acute Myeloid Leukemia

Leukemia
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Study of Tumor Samples From Patients With Ependymoma Treated on the Children's Oncology Group ACNS0121 Trial

Childhood Infratentorial Ependymoma | Childhood Supratentorial Ependymoma | Newly Diagnosed Childhood Ependymoma

United States
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Study to Predict Risk of Relapse in Bone Marrow Cell Samples From Younger Patients With Acute Myeloid Leukemia

Leukemia

Clinical Trials Sponsored by Children's Discovery Institute

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