Clinical Trials Sponsored by Duke Clinical Research Institute

Total 1843 results

National Human Genome Research Institute (NHGRI)

Recruiting

New Technology and Child Health

Healthy Volunteers

United States
National Human Genome Research Institute (NHGRI)

Recruiting

The NIH MINI Study: Metabolism, Infection, and Immunity in Inborn Errors of Metabolism

Mitochondrial Disorders | Leigh Disease | Oxidative Phosphorylation Deficiencies | Electron Transport Chain Disorders, Mitochondrial

United States
National Institute of Nursing Research (NINR)

Recruiting

Characterizing Fatigue Experienced by Cancer Patients Receiving Primary Treatment and Cancer Survivors

Cancer | Breast Cancer | Fatigue | Prostate Cancer | Cancer Survivor

United States
National Human Genome Research Institute (NHGRI)

Recruiting

Analysis of Specimens From Individuals With Pulmonary Fibrosis

Pulmonary Fibrosis | Healthy Volunteers | Hermansky-Pudlak Syndrome (HPS)

United States
National Human Genome Research Institute (NHGRI)

Recruiting

Study of Chediak-Higashi Syndrome

Chediak-Higashi Syndrome

United States
National Human Genome Research Institute (NHGRI)

Completed

New Approaches for Empowering Studies of Asthma in Populations of African Descent

Asthma

United States
National Human Genome Research Institute (NHGRI)

Completed

Genomics, Environmental Factors and Social Determinants of Cardiovascular Disease in African-Americans Study (GENE-FORECAST): Prospective COVID-19 Natural History Study

Heart Disease

United States
National Human Genome Research Institute (NHGRI)

Enrolling by invitation

Genetics of Obesity, Diabetes, and Heart Disease in African Diaspora Populations

Cardiovascular Disease | Diabetes

United States
National Human Genome Research Institute (NHGRI)

Active, not recruiting

ClinSeq: A Large-Scale Medical Sequencing Clinical Research Pilot Study

Healthy Volunteers | Atherosclerotic Heart Disease

United States
National Human Genome Research Institute (NHGRI)

Active, not recruiting

Genomics, Environmental Factors and Social Determinants of Cardiovascular Disease in African Americans Study (GENE-FORECAST): Sodium Intervention Trial (SIT)

Cardiovascular Disease

United States
National Human Genome Research Institute (NHGRI)

Completed

Where Culture Meets Genetics: Exploring Latinas Causal Attributions of Breast and Colon Cancer and Models of Disease Inheritance

Breast Cancer | Colon Cancer

United States
National Human Genome Research Institute (NHGRI)

Completed

Patient Provider Communication and Interaction in a Virtual Clinical Setting

Healthy Volunteer

United States
National Institute of Nursing Research (NINR)

Terminated

Immersive VR Environments to Induce and Evaluate Cognitive Fatigability

Cognitive Fatigue

United States
National Human Genome Research Institute (NHGRI)

Completed

A Study of the Genetic Analysis of Brain Disorders

Holoprosencephaly

United States
National Institute of Nursing Research (NINR)

Withdrawn

Characterization of Fatigue in Military Personnel With Traumatic Brain Injuries

Fatigue | Sleep Disorder | Traumatic Brain Injury | Neurobehavioral Manifestation

United States
National Human Genome Research Institute (NHGRI)

Completed

Genetics of Type 2 Diabetes Among Han Chinese

Hypertension | Diabetes

China
National Institute of Nursing Research (NINR)

Completed

Evaluation and Diagnosis of People With Pain and Fatigue Syndromes

Fatigue

United States
National Human Genome Research Institute (NHGRI)

Completed

Personalized Genomic Research

Genetics | Birth Defects | Genetic Disease | Genetic Linkage | Genetic Variation

United States
National Human Genome Research Institute (NHGRI)

Completed

Mapping Genes for Type 2 (Non-Insulin Dependent) Diabetes Mellitus

Diabetes | Genetic Variation

Norway, Finland
National Human Genome Research Institute (NHGRI)

Completed

Family Myopia Study

Myopia

United States
National Human Genome Research Institute (NHGRI)

Completed

The Genetic Basis of Acquired Heart Disease in Africa

Acquired Heart Disease | Rheumatic Heart Disease | Rheumatic Fever | Endomyocardial Fibrosis

Uganda, Nigeria
National Human Genome Research Institute (NHGRI)

Completed

Analysis of Data From the Women's Contraceptive and Reproductive Experiences (CARE) Study

Breast Cancer

United States
National Human Genome Research Institute (NHGRI)

Completed

The Experience of Caregivers of Children With Down Syndrome

Down Syndrome

United States
National Human Genome Research Institute (NHGRI)

Completed

Adaptation and Quality of Life Among Adults With Neurofibromatosis Type I

Neurofibromatosis Type 1 | NF1 | Von Recklinghausen Disease

United States
National Institute of Nursing Research (NINR)

Terminated

Developing Therapies for Traumatic Brain Injury

Traumatic Brain Injury

United States
National Human Genome Research Institute (NHGRI)

Completed

Treatment Strategies for Children With Smith-Magenis Syndrome

Mental Retardation | Sleep Disorders, Circadian Rhythm | Developmental Delay Disorders | Chromosome Deletion | Self Injurious Behavior

United States
National Human Genome Research Institute (NHGRI)

Completed

Gene Transfer Therapy for Severe Combined Immunodeficieny Disease (SCID) Due to Adenosine Deaminase (ADA) Deficiency

Severe Combined Immunodeficiency Syndrome

United States
National Institute of Nursing Research (NINR)

Terminated

Development of a Proxy Motor Outcome Measure in Young Children With Neuromuscular Disease

Neuromuscular Disease

United States
National Human Genome Research Institute (NHGRI)

Completed

Positive Exposure: A Photography and Video Intervention for Individuals With Craniofacial Differences

Craniofacial Differences

United States
National Institute of Nursing Research (NINR)

Terminated

Study of Proteins Associated With Complex Regional Pain Syndrome

Healthy | Complex Regional Pain Syndromes

United States
National Human Genome Research Institute (NHGRI)

Terminated

The Role of Family Functioning in Promoting Adaptation in Siblings of Individuals With Duchenne Muscular Dystrophy (DMD)

Communication | Genetic Disease

United States
National Human Genome Research Institute (NHGRI)

Terminated

Genetic Analysis of Neural Tube and Orofacial Cleft Defects in the Irish Population

Hereditary Oral Clefts | Neural Tube Defects (NTDs) | Facial Cleft Defect

United States
National Human Genome Research Institute (NHGRI)

Terminated

Genetics and Clinical Characteristics of Bardet-Biedl Syndrome

Bardet-Biedl Syndrome

United States
National Human Genome Research Institute (NHGRI)

Completed

The Role of Social Comparisons in Coping and Quality of Life Following a Prostate Cancer Diagnosis

Prostate Cancer

United States
National Human Genome Research Institute (NHGRI)

Completed

Use of Population Descriptors in Human Genetic Research

Disease | Qualitative Research | Population Groups | Genetics, Medical | Ethnology

United States
National Institute of Nursing Research (NINR)

Terminated

Effect of Ketamine on Fatigue Following Cancer Therapy

Cancer | Fatigue | Ketamine

United States
National Human Genome Research Institute (NHGRI)

Completed

Informed Consent for Whole Genome Sequencing: Ideals and Norms Referenced by Early Participants

Coronary Artery Disease | Proteus Syndrome | Familial Isolated Hyperparathyroidism | Coffin - Sins Syndrome | Dubouitz Syndrome

United States
National Human Genome Research Institute (NHGRI)

Terminated

Living With Frontotemporal Dementia

Adaptation

United States
National Human Genome Research Institute (NHGRI)

Completed

Where Does Hope Fit In? The Relationship Between Hope, Uncertainty, and Coping Efficacy in Mothers of Children With Duchenne/Becker Muscular Dystrophy

Stress

United States
National Human Genome Research Institute (NHGRI)

Completed

Perspectives of Individuals With Bipolar Disorder and Siblings of Individuals With Bipolar Disorder; A Telephone Interview Study

Bipolar Disorder (BD) | Bipolar

United States
National Human Genome Research Institute (NHGRI)

Completed

The Roles of Trust and Respect in Patient Reactions to Race-based and Personalized Medicine Vignettes: An Experimental Study

Hypertension | Diabetes | Congenital Heart Disease

United States
National Human Genome Research Institute (NHGRI)

Completed

Influence of Genetics on Vitamin Metabolism in Pregnant Women

Pregnancy | Birth Defects

Ireland
National Human Genome Research Institute (NHGRI)

Completed

Informed Choice Regarding Invasive Prenatal Testing

Pregnancy - Prenatal Testing

United States
National Human Genome Research Institute (NHGRI)

Completed

Prevalence of Ambivalence Regarding Prenatal Testing

Pregnancy

United States
National Human Genome Research Institute (NHGRI)

Completed

Making Sense of a Positive Genetic Test Result for Huntington Disease

Huntington Disease

United States
National Human Genome Research Institute (NHGRI)

Completed

Molecular Analysis of Microphthalmia/Anophthalmia

Anophthalmos

United States
National Human Genome Research Institute (NHGRI)

Completed

Genetic Analysis of Parkinson's Disease

Parkinson's Disease

United States
National Human Genome Research Institute (NHGRI)

Completed

Microarray Analysis for Human Genetic Disease

Melanoma | Breast Neoplasm | Ovarian Neoplasm | Hereditary Neoplastic Syndrome

United States, Finland, Iceland, Sweden
National Human Genome Research Institute (NHGRI)

Completed

Patients' Perspectives on Identity, Ancestry and Genetics

Family History

United States
National Human Genome Research Institute (NHGRI)

Completed

Genetic Studies of Inflammatory Bowel Disease

Inflammatory Bowel Disease

United States

Clinical Trials Sponsored by Duke Clinical Research Institute

Sponsors and Collaborators

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CROs in Rwanda

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Rare Diseases

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